Ik-sung Ahn
Yonsei University · Biochemistry, Genetics and Molecular Biology
About the Lab
Professor Ik-sung Ahn's research lab specializes in environmental biotechnology and biochemical engineering, focusing on the microbial degradation of environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds. The lab investigates microbial kinetics, enzyme mechanisms, and the development of biosensors and immobilized enzyme systems for bioremediation and biocatalysis. Key research directions include the design of selective probes for proteases like cathepsin B, the application of deep-sea extremophiles for CO₂ conversion, and the integration of microscale kinetic models into macroscale transport predictions for contaminant fate in soils. The lab also develops advanced functional materials, such as metal-chelated magnetic nanoparticles, for efficient enzyme immobilization and environmental applications.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15The objectives of this work were (1) to demonstrate how the chemostat approach could be modified to allow determination of kinetic parameters for a sparingly soluble, volatile substrate such as naphthalene and (2) to examine the influence of the interactions of various nutrients on possible growth-inhibitory effects of naphthalene. Pseudomonas putida G7 was used as a model naphthalene-degrading microorganism. Naphthalene was found to be toxic to P. putida G7 in the absence of a nitrogen source o
Cathepsin B has been suggested to be a prognostic marker of melanoma, glioma, and a variety of cancers such as brain, breast, colon, esophageal, gastric, lung, ovarian, and thyroid cancers. Cathepsin B inhibitors have also been considered as anticancer drug candidates; hence, there has been a growing need for a probe which enables the selective and simple detection of cathepsin B and its inhibitors. For the purpose of selective assay, a cathepsin B-specific substrate, N,N'-diBoc-dityrosine-glyci
Biological conversion of high-concentration CO<sub>2</sub>in the emission gases using a deep-sea sulfur oxidizing bacterium.
Magnetic particles of size 10 nm have been coated with silica to a mean diameter of 40 nm and charged with Cu2+ ions via a multidentate ligand, iminodiacetic acid (IDA), for the immobilization of His-tagged Bacillus stearothermopilus L1 lipase. Microporous (average pore diameter of 60 Å) silica gel with a mean particle diameter of 115 µm has been used as a comparative support material. The molar ratio of Cu2+ to IDA was found to be 1:1.14 and 1:1.99 in the silica gel and the silica-coated magnet
Three models for sorption/desorption of polycyclic aromatic hydrocarbon (PAH) contaminants from soil were compared for their ability to predict the transport of PAH in soil: a “gamma” model, a “two-site/two-region” nonequilibrium model, and a “hybrid” model. In the “hybrid” model, soil organic matter was conceptually divided into two compartments; a fraction with rapid sorption/desorption kinetics and a compartment with mass-transfer-limited kinetics. Contaminant sorbed in the rapid compartment
Research Areas
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