Jae-Gwan Lee
Korea University · Medicine
About the Lab
Professor Jae-Gwan Lee's research lab specializes in materials science and biomedical engineering, focusing on the development of advanced functional materials and their applications in health and energy systems. The lab investigates quasicrystalline and amorphous alloys for improved material properties, explores mitochondrial dynamics in viral infections such as Zika virus, and designs novel ultra-wideband filters using defected ground structures for next-generation communication systems. Additionally, the lab contributes to preventive oncology by studying the role of lifestyle factors in cervical cancer risk. These diverse research directions reflect a strong emphasis on interdisciplinary innovation at the intersection of materials engineering, virology, and biomedical applications.
Research Overview
Research Output Trend
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Selected Papers
15We develop a search procedure for project scheduling problems with multiple resource constraints as well as precedence constraints. The procedure is applied to three popular search heuristics, simulated annealing, tabu search and genetic algorithms. In the heuristics, a solution is represented with a string of numbers each of which denotes priority of each activity. The priorities are used to select an activity for scheduling among competing ones. The search heuristics with this encoding method
<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> A novel ultra-wideband (UWB) bandpass filter (BPF) with improved upper stopband performance using a defected ground structure (DGS) is presented in this letter. The proposed BPF is composed of seven DGSs that are positioned under the input and output microstrip line and coupled double step impedance resonator (CDSIR). By using CDSIR and open loop defected ground structure (OLDGS), we can achieve UWB
Our results indicate that in addition to screening for and treatment of CIN, recommendations on the maintenance of an appropriate BMI with an emphasis on physical activity could be an important preventive strategy against the development of cervical cancer.
The functional organization of the human insulin receptor (hIR) promoter was analyzed by deletion mutagenesis and protein-DNA interaction studies. A series of deletion mutants was expressed transiently in two human hepatocytes, HepG2 and PLC. The results revealed that the promoter region between -692 and -345 is essential for efficient transcription of the hIR gene. Multiple trans-acting factors were identified by band shift and footprinting analyses. Sp1 binds to a cluster of GC boxes and two G
Zika virus (ZIKV) remains a global public health threat with the potential risk of a future outbreak. Since viral infections are known to exploit mitochondria-mediated cellular processes, we investigated the effects of ZIKV infection in trophoblast cells in terms of the different mitochondrial quality control pathways that govern mitochondrial integrity and function. Here we demonstrate that ZIKV (PRVABC59) infection of JEG-3 trophoblast cells manipulates mitochondrial dynamics, mitophagy, and f
The kinetic behavior of quasicrystalline phase formation in amorphous Zr65Al7.5Cu12.5Ni10Ag5 alloys has been studied by using differential scanning calorimetry (DSC), x-ray diffractometry, and transmission electron microscopy. DSC trace obtained during continuous heating from 473 to 873 K shows two distinct exotherms with peak temperatures of 727 and 776 K. The first and second exothermic reactions, respectively, correspond to the formation of quasicrystalline phase from the amorphous matrix and
Cervical cancer, the fourth most common cancer among women worldwide, often proves fatal and stems from precursor lesions caused by high-risk human papillomavirus (HR-HPV) infection. Accurate and early diagnosis is crucial for effective treatment. Current screening methods, such as the Pap test, liquid-based cytology (LBC), visual inspection with acetic acid (VIA), and HPV DNA testing, have limitations, requiring confirmation through colposcopy. This study introduces CerviCARE AI, an artificial
BACKGROUND: The association between coffee intake and type 2 diabetes may be modulated by common genetic variation. OBJECTIVE: The purpose of this study was to examine the association between habitual coffee intake and the risk of type 2 diabetes and to determine whether this association varied by genetic polymorphisms related to type 2 diabetes in Korean adults. DESIGN AND METHODS: A population-based cohort study over a follow-up of 4 years was conducted. A total of 4077 Korean men and women ag
Research Areas
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