Jae Ho Jung
Seoul National University · Medicine
About the Lab
Professor Jae Ho Jung's research lab specializes in ophthalmic pharmacology and surgical ophthalmology, with a focus on the mechanisms of prostaglandin analogs in orbital fat metabolism and their clinical implications in ocular surface and orbital disorders. The lab investigates the pathophysiology of conditions such as deep superior sulcus syndrome and Miller Fisher syndrome, particularly in pediatric populations, and explores surgical techniques for orbital and extraocular muscle disorders. Additionally, the lab examines drug delivery dynamics, including the intraocular pharmacokinetics of triamcinolone acetonide after vitrectomy, to optimize therapeutic outcomes.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15PURPOSE: To investigate the effect of prostaglandin F2α (PGF2α), latanoprost, travoprost, bimatoprost, and tafluprost on human orbital preadipocyte differentiation and intracellular lipid storage, and to reveal the potential mechanisms by which topical prostaglandin analogs induce orbital fat volume reduction and cause deep superior sulcus syndrome. METHODS: Human orbital adipose precursors were treated in vitro for 24 h (day 1) with PGF2α, latanoprost, travoprost, bimatoprost, and tafluprost in
In this series, the functional outcomes of vitrectomy for vitreous hemorrhage associated with AMD were inferior to outcomes of the PCV group. Vitrectomy is beneficial for improving visual function in select cases of breakthrough vitreous hemorrhage.
This surgical technique is an effective method for the correction of coexistent epiblepharon and epicanthal fold without significant complications.
BACKGROUND: We aimed to investigate the characteristic presentation of Miller Fisher syndrome (MFS) in pediatrics and compare it with that in adults. METHODS: We performed a retrospective review of medical records, laboratory findings, and disease course of pediatric MFS. The data were compared with those of adult MFS, and literature review was done. Unpaired and paired comparisons between groups were made using Wilcoxon rank-sum and signed-rank tests, respectively. RESULTS: Median age for pedia
Intravitreal absorption and excretion of TA in the posterior subtenon space are increased after vitrectomy. Although the terminal half-life of TA was shorter, higher early concentration and similar effective duration were achieved in the vitrectomized eyes.
The intraoperative use of bevacizumab reduced inflammatory cell infiltration in the early stage of the procedure, but it was insufficient to prevent postoperative adhesion in rabbit eyes after extraocular muscle surgery.
BACKGROUND: Patients with strabismus are more likely to have mental health problems, including high rates of depressive symptoms and social phobia. Intermittent exotropia (IXT) typically occurs in early childhood and is more common in Asian populations. We aim to assess the health-related quality of life (HRQOL) concerns in children with intermittent exotropia (IXT) using the Intermittent Exotropia Questionaire (IXTQ), and their associations with the clinical severity of IXT and the parents' HRQ
주민참여예산제는 2004년 이후 참여민주적 재정통제장치로서 지방자치단체에 도입되어 2014년 현재 2개의 기초지자체를 제외한 모든 지방자치단체에서 시행되고 있다. 주민참여예산제가 정착됨에 따라 본 논문은 주민참여예산제가 지방재정 건전성 통제장치로서 유효한 역할을 살펴보고자 하였다. 이를 위하여 기초지방자치단체의 선심성 및 전시성 예산을 재정건전성의 대리변수로 선택하여 종속변수로 하였고, 독립변수는 주민참여예산제 도입여부로 하였다. 또한 모형의 설명력을 높이기 위하여 재정자립도, 지방자치단체장 소속정당, 지방선거 투표율, 65세 이상 노령인구비율, 도시지역 여부를 통제변수로서 모형에 포함하였고, 이들 변수들에 대한 2004년에서 2012년까지의 자료를 수집하여 통합회귀분석을 실시하였다. 분석결과 주민참여예산제의 도입은 주민 1인당 절대액으로 정의한 지방자치단체의 선심성 및 전시성예산에 대하여 통계적으로 유의하게 양(+)의 영향을 미치는 것으로 나타났다. 이와 같은 결과는 통제변수를 추
PURPOSE: This study was intended to evaluate the effect of horizontal muscle surgery on anterior segment measurements in patients with strabismus. METHODS: Forty-two eyes of 28 patients with exotropia undergoing recession or recession combined with resection procedure were included. Consecutive cases were imaged using a Pentacam (Oculus, Inc., Berlin, Germany) immediately prior to surgery and 1 and 3 months after surgery. The refractive power of the anterior surface of the cornea on the horizont
Research Areas
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