Jaegyeom Sim
Korea University · Medicine
About the Lab
Professor Jaegyeom Sim's research lab focuses on clinical and translational studies in internal medicine, with a strong emphasis on rare and complex systemic diseases, including IgG4-related disease, hypereosinophilic syndromes, and complications of common medical treatments such as iron supplement aspiration. The lab investigates clinical presentations, diagnostic challenges, and outcomes in critical care settings, particularly in intensive care units where post-extubation respiratory support and cardiac dysfunction are key concerns. Research also explores patient-centered language in reproductive health, reflecting a broader interest in clinical communication and stigma reduction in sensitive medical contexts.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
11BACKGROUND: The phrase 'termination of pregnancy' has recently been adopted by a number of British medical institutions as a preferred descriptor of induced abortion. How it is used by abortion care providers is unclear, although the ongoing stigmatisation of abortion may play a role. METHODS: A mixed methods study of the views of abortion care providers in Scotland, UK. Self-administered anonymous questionnaires were distributed to abortion care providers at a national conference (Scottish Abor
Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have bee
Background: Cardiac dysfunction patients have long been considered at high risk of reintubation. However, it is based on past studies in which only conventional oxygen therapy was applied after extubation. We investigated association between cardiac dysfunction and reintubation rate in situation where high-flow nasal cannula (HFNC) was widely used during post-extubation period.Methods: We conducted a retrospective observational cohort study of patients treated with HFNC after planned extubation
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Although endobronchial hamartoma is a rare benign tumor, most patients with endobronchial hamartoma have respiratory symptoms such as obstructive pneumonia, hemoptysis, cough, or dyspnea due to bronchial obstruction. It can cause irreversible post-obstructive pulmonary destruction, thus early diagnosis and treatment is very important. Recently, there have been cases of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser and electrocautery procedures for bronchoscopic treatment of malignant or
Background: Mechanical power (MP), which integrates ventilator variables affecting ventilator-induced lung injury, has been reported to be associated with clinical outcomes. Because the original MP equation is derived from paralyzed patients under volume-controlled ventilation, its application in practice could be limited in patients receiving pressure-controlled ventilation (PCV). Recently, a simplified equation for patients under PCV was developed. We investigated the association between MP an
Introduction: To investigate the understanding of breast-feeding in pregnant woman and proper way of encouraging breast-feeding. Methods: Each questionnaire included items on the understanding of breast-feeding. The Questionnaires were filled up by pregnant women visiting obstetric clinics in Seoul and its vicinities, Busan, Choongjoo and Chungjoo from July to August 2001. 1290 questionnaires were analyzed by Chi square test and multiple logistic regression. A follow-up survey was done by teleph
Iron supplements such as ferrous sulfate tablets are usually used to treat iron-deficiency anemia in some elderly patients with primary neurologic disorders or decreased gag reflexes due to stroke, senile dementia, or parkinsonism. While the aspiration of ferrous sulfate is rarely reported, it is a potentially life-threatening condition that can lead to airway necrosis and bronchial stenosis. A detailed history and high suspicion of aspiration are required to avoid delays in diagnosis and treatm
Hypereosinophilia is often associated with eosinphilic infiltration of tissue, which can lead to severe and irreversible organdamage. One of the most characteristic and critical complications is development of thrombosis in cardiac ventricles, and occasionallyin deep veins. We report a rare case of hypereosinophilia, with peripheral vascular thrombosis, caused by Toxocara canisinfection.
Background/Aims: Despite several reports on clinical aspects of anemia and malignancy, little is known of male patients withiron-deficiency anemia (IDA) and malignancy in Korea. We examined the cause of anemia, prevalence of and factors associatedwith malignancy, and treatment response to iron therapy in male IDA patients. Methods: The results of 202 males with IDA seen from March 2008 to June 2013 were analyzed retrospectively. The patients weredivided into two groups based on the causes of ane
Research Areas
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