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Janghyun Baek

Sungkyunkwan University · Medicine

About the Lab

Professor Janghyun Baek's research lab specializes in endovascular interventions for acute ischemic stroke, with a primary focus on mechanical thrombectomy using stent retrievers and adjunctive techniques such as balloon guide catheters. The lab investigates predictors of treatment success, including angiographic occlusion morphology, procedural strategies, and hemodynamic optimization to improve recanalization and functional outcomes. Key research directions include identifying optimal treatment thresholds, evaluating rescue techniques after thrombectomy failure, and refining pre-procedural imaging biomarkers—particularly using CTA—for accurate occlusion type classification and treatment planning.

mechanical thrombectomyintracranial atherosclerosisrecanalizationendovascular treatmentocclusion morphology

Research Overview

Papers
90
Total Citations
2,177
Papers (5y)
50
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
50total
2021
2022
2023
2024
2025
Citations per year (5y)
627total
20212022202320242025

Selected Papers

15
1
Article|159 citations·2018
Outcomes of Endovascular Treatment for Acute Intracranial Atherosclerosis–Related Large Vessel Occlusion
Jang‐Hyun Baek, Byung Moon Kim, Ji Hoe Heo, Dong Joon Kim, Hyo Suk Nam, Young Dae Kim
SJR Q1StrokeOA

Background and Purpose- Endovascular treatment for acute intracranial atherosclerosis-related large vessel occlusion (ICAS [+]-LVO) is one of the challenging issues in modern mechanical thrombectomy era. We evaluated procedural and clinical outcomes of endovascular treatment for the ICAS (+)-LVO. We also compared their outcomes with those of large vessel occlusion not associated with intracranial atherosclerosis (ICAS [-]-LVO). Methods- We retrospectively reviewed consecutive patients with acute

EpidemiologyMedicine
2
Article|130 citations·2016
Stenting as a Rescue Treatment After Failure of Mechanical Thrombectomy for Anterior Circulation Large Artery Occlusion
Jang‐Hyun Baek, Byung Moon Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam, Joonsang Yoo
SJR Q1StrokeOA

BACKGROUND AND PURPOSE: We hypothesized that permanent stenting may be a rescue treatment for stentriever-failed anterior circulation large artery occlusion. We compared the outcomes among patients with permanent stenting and those without stenting after stentriever failure. METHODS: We retrospectively evaluated 208 patients who underwent stentriever thrombectomy for anterior circulation large artery occlusion between September 2010 and September 2015. Modified thrombolysis in cerebral ischemia

EpidemiologyMedicine
3
Article|119 citations·2016
Importance of truncal-type occlusion in stentriever-based thrombectomy for acute stroke
Jang‐Hyun Baek, Byung Moon Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam, Dongbeom Song, Oh Young Bang
SJR Q1NeurologyOA

Angiographic occlusion type is an independent predictor of stentriever refractoriness and of the underlying stroke mechanism.

EpidemiologyMedicine
4
Article|118 citations·2018
Number of Stent Retriever Passes Associated With Futile Recanalization in Acute Stroke
Jang‐Hyun Baek, Byung Moon Kim, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim, Hyungjong Park, Oh Young Bang, Joonsang Yoo, Dong Joon Kim, Pyoung Jeon, Seung Kug Baik, Sang Hyun Suh
SJR Q1StrokeOA

Background and Purpose- Stent retriever (SR) thrombectomy has become the mainstay of treatment of acute intracranial large artery occlusion. However, it is still not much known about the optimal limit of SR attempts for favorable outcome. We evaluated whether a specific number of SR passes for futile recanalization can be determined. Methods- Patients who were treated with a SR as the first endovascular modality for their intracranial large artery occlusion in anterior circulation were retrospec

EpidemiologyMedicine
5
Article|77 citations·2019
Balloon Guide Catheter Is Beneficial in Endovascular Treatment Regardless of Mechanical Recanalization Modality
Jang‐Hyun Baek, Byung Moon Kim, Dong-Hun Kang, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim, Yang‐Ha Hwang, Yong-Won Kim, Yong‐Sun Kim, Dong Joon Kim, Hyo Sung Kwak, Hong Gee Roh
SJR Q1StrokeOA

Background and Purpose- Based on its mechanism, the use of balloon guide catheters (BGCs) may be beneficial during endovascular treatment, regardless of the type of mechanical recanalization modality used-stent retriever thrombectomy or thrombaspiration. We evaluated whether the use of BGCs can be beneficial regardless of the first-line mechanical endovascular modality used. Methods- We retrospectively reviewed consecutive acute stroke patients who underwent stent retriever thrombectomy or throm

EpidemiologyMedicine
6
Article|53 citations·2017
Predictive Value of Computed Tomography Angiography–Determined Occlusion Type in Stent Retriever Thrombectomy
Jang‐Hyun Baek, Byung Moon Kim, Joonsang Yoo, Hyo Suk Nam, Young Dae Kim, Dong Joon Kim, Ji Hoe Heo, Oh Young Bang
SJR Q1StrokeOA

Background and Purpose— We investigated whether occlusion type identified with computed tomography angiography (CTA-determined occlusion type) could predict endovascular treatment success using stent retriever (SR) thrombectomy. Methods— Consecutive patients with stroke who underwent CTA and then endovascular treatment for intracranial large artery occlusion were retrospectively reviewed. CTA-determined occlusion type was classified into truncal-type occlusion or branching-site occlusion and com

EpidemiologyMedicine
7
Review|42 citations·2019
Angiographical Identification of Intracranial, Atherosclerosis-Related, Large Vessel Occlusion in Endovascular Treatment
Jang‐Hyun Baek, Byung Moon Kim
SJR Q2Frontiers in NeurologyOA

Identification of intracranial, atherosclerosis-related, large vessel occlusion (ICAS-LVO) is important to set up an optimal endovascular treatment strategy, as most ICAS-LVOs require specific endovascular modalities for efficient recanalization. However, there is currently no decisive way to identify ICAS-LVO for endovascular treatment. Instead of the few, non-specific, clinical and imaging findings that operators have depended on, this review focused on the occlusion type, one of angiographica

EpidemiologyMedicine
8
Article|40 citations·2010
Favorable Influence of Subclinical Hypothyroidism on the Functional Outcomes in Stroke Patients
Jang‐Hyun Baek, Pil‐Wook Chung, Yong Bum Kim, Heui‐Soo Moon, Bum Chun Suh, Dong-Kwan Jin, Byung Moon Kim, Eun‐Jung Rhee, Yong Taek Lee, Kwang‐Yeol Park
SJR Q2Endocrine JournalOA

Subclinical hypothyroidism (SCH) is thought to have an influence on stroke outcomes. However, few reports demonstrate a favorable relationship between the two. We evaluated this association in acute ischemic stroke. From Jan 2005 to June 2008, 756 acute ischemic stroke patients were recruited within seven days of onset. The patients with overt hypothyroidism/hyperthyroidism or other medical conditions that may affect thyroid function were excluded. Thyroid stimulating hormone (TSH) and free thyr

Endocrinology, Diabetes and MetabolismMedicine
9
Article|40 citations·2017
Predictive value of thrombus volume for recanalization in stent retriever thrombectomy
Jang‐Hyun Baek, Joonsang Yoo, Dongbeom Song, Young Dae Kim, Hyo Suk Nam, Byung Moon Kim, Dong Joon Kim, Hye Sun Lee, Ji Hoe Heo
SJR Q1Scientific ReportsOA

Abstract This retrospective study investigated whether the volume or density of the thrombus is predictive of recanalization in stent retriever (SR) treatment. Consecutive patients treated with SR thrombectomy as the first endovascular modality were enrolled. The thrombus volume and density were measured on thin-section noncontrast computed tomography using 3-dimensional software. The patients were grouped by recanalization status and the number of SR passes. Among 165 patients, recanalization w

EpidemiologyMedicine
10
Article|34 citations·2020
Utility of Leptomeningeal Collaterals in Predicting Intracranial Atherosclerosis-Related Large Vessel Occlusion in Endovascular Treatment
Jang‐Hyun Baek, Byung Moon Kim, Jin Woo Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim
SJR Q1Journal of Clinical MedicineOA

Earlier or preprocedural identification of occlusion pathomechanism is crucial for effective endovascular treatment. As leptomeningeal collaterals tend to develop well in chronic ischemic conditions such as intracranial atherosclerosis (ICAS), we investigated whether leptomeningeal collaterals can be a preprocedural marker of ICAS-related large vessel occlusion (ICAS-LVO) in endovascular treatment. A total of 226 patients who underwent endovascular treatment were retrospectively reviewed. We com

EpidemiologyMedicine
11
Article|25 citations·2019
Endovascular and Clinical Outcomes of Vertebrobasilar Intracranial Atherosclerosis-Related Large Vessel Occlusion
Jang‐Hyun Baek, Byung Moon Kim, Ji Hoe Heo, Dong Joon Kim, Hyo Suk Nam, Young Dae Kim
SJR Q2Frontiers in NeurologyOA

<b>Background and Purpose:</b> Endovascular treatment (EVT) for acute vertebrobasilar intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) and its outcomes are not well known. We aimed to evaluate endovascular and clinical outcomes of vertebrobasilar ICAS-LVO patients who underwent EVT. <b>Methods:</b> Consecutive acute stroke patients who underwent EVT for vertebrobasilar LVO were retrospectively reviewed. Patients were assigned to the ICAS (+) or the ICAS (-) group based on a

EpidemiologyMedicine
12
Article|25 citations·2022
Clinical outcomes of rescue stenting for failed endovascular thrombectomy: a multicenter prospective registry
Jang‐Hyun Baek, Byung Moon Kim, Byung Moon Kim, Eun Hyun Ihm, Chang‐Hyun Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam, Young Dae Kim, Sang‐il Suh, Byungjun Kim, Byungjun Kim
SJR Q1Journal of NeuroInterventional SurgeryOA

BACKGROUND: Mechanical thrombectomy (MT) is a primary endovascular modality for acute intracranial large vessel occlusion. However, further treatment, such as rescue stenting, is occasionally necessary for refractory cases. We aimed to investigate the efficacy and safety of rescue stenting in first-line MT failure and to identify the clinical factors affecting its clinical outcome. METHODS: A multicenter prospective registry was designed for this study. We enrolled consecutive patients who under

EpidemiologyMedicine
13
Article|14 citations·2017
The Protective Effect of Middle Cerebral Artery Calcification on Symptomatic Middle Cerebral Artery Infarction
Jang‐Hyun Baek, Joonsang Yoo, Dongbeom Song, Young Dae Kim, Hyo Suk Nam, Ji Hoe Heo
SJR Q1StrokeOA

Background and Purpose— The presence of intracranial artery calcification is associated with an increased risk for stroke. However, calcified atherosclerotic plaques are also known to be less vulnerable to rupture. Given this discrepancy, we investigated whether the vulnerability of intracranial arterial atherosclerosis differed based on the presence or absence of calcification. Methods— We considered consecutive patients with acute stroke in the unilateral middle cerebral artery (MCA) territory

Pulmonary and Respiratory MedicineMedicine
14
Article|14 citations·2021
Low Hypoperfusion Intensity Ratio Is Associated with a Favorable Outcome Even in Large Ischemic Core and Delayed Recanalization Time
Jang‐Hyun Baek, Young Dae Kim, Ki Jeong Lee, Jin Kyo Choi, Minyoul Baik, Byung Moon Kim, Dong Joon Kim, Ji Hoe Heo, Hyo Suk Nam
SJR Q1Journal of Clinical MedicineOA

In ischemic brain tissue, hypoperfusion severity can be assessed using the hypoperfusion intensity ratio (HIR). We evaluated the link between HIR and clinical outcomes after successful recanalization by endovascular treatment. We retrospectively reviewed 162 consecutive patients who underwent endovascular treatment for intracranial large vessel occlusion. The HIR was calculated using an automated software program, with initial computed tomography perfusion images. The HIR was compared between pa

EpidemiologyMedicine
15
Review|8 citations·2023
Carotid Artery Stenting for Asymptomatic Carotid Stenosis: What We Need to Know for Treatment Decision
Jang‐Hyun Baek
SJR Q2NeurointerventionOA

A clinical decision on the treatment of asymptomatic carotid stenosis is challenging, unlike symptomatic carotid stenosis. Carotid artery stenting (CAS) has been recommended as an alternative to carotid endarterectomy (CEA) based on the finding that the efficacy and safety of CAS were comparable to CEA in randomized trials. However, in some countries, CAS is often performed more frequently than CEA for asymptomatic carotid stenosis. Moreover, it has been recently reported that CAS is not superio

Pulmonary and Respiratory MedicineMedicine

Research Areas

EpidemiologyCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineOncologyNeurologyEndocrinology, Diabetes and Metabolism

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