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Jee Youn Moon

Seoul National University · Medicine

About the Lab

Professor Jee Youn Moon's research lab specializes in clinical pain management and neuromodulation, with a focus on improving patient outcomes through innovative non-pharmacological and pharmacological interventions. The lab investigates the application of virtual reality as a non-sedative distraction technique during spinal anesthesia, explores predictive clinical factors for radiofrequency thermocoagulation success in trigeminal neuralgia, and develops and validates pain assessment tools such as the Korean version of the painDETECT questionnaire. Additionally, the lab examines the neuropharmacological mechanisms of analgesics like nefopam and natural compounds such as eugenol on GABAergic signaling in sensory neurons.

pain managementneuromodulationvirtual realitytrigeminal neuralgiaGABA receptors

Research Overview

Papers
138
Total Citations
2,672
Papers (5y)
36
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
36total
2022
2023
2024
2025
2026
Citations per year (5y)
103total
20222023202420252026

Selected Papers

15
1
Article|62 citations·2018
Virtual Reality Distraction during Endoscopic Urologic Surgery under Spinal Anesthesia: A Randomized Controlled Trial
Jee Youn Moon, Jungho Shin, Jaeyeon Chung, Sang‐Hwan Ji, Soohan Ro, Won Ho Kim
SJR Q1Journal of Clinical MedicineOA

Sedation protocols during spinal anesthesia often involve sedative drugs associated with complications. We investigated whether virtual reality (VR) distraction could be applied during endoscopic urologic surgery under spinal anesthesia and yield better satisfaction than pharmacologic sedation. VR distraction without sedative was compared with pharmacologic sedation using repeat doses of midazolam 1–2 mg every 30 min during urologic surgery under spinal anesthesia. We compared the satisfaction o

Anesthesiology and Pain MedicineMedicine
2
Article|47 citations·2018
Efficacy and Safety of Lidocaine Infusion Treatment for Neuropathic Pain
Yong Chul Kim, Anyela Marcela Castañeda, Chang-Soon Lee, Hyun‐Seung Jin, Keun Seok Park, Jee Youn Moon
SJR Q1Regional Anesthesia & Pain Medicine

This study was registered at ClinicalTrials.gov, identifier NCT02597257.

PhysiologyMedicine
3
Article|44 citations·2015
Predictive Factors Associated with Success andFailure for Radiofrequency Thermocoagulationin Patients with Trigeminal Neuralgia
Jee Youn Moon
SJR Q1Pain PhysicianOA

BACKGROUND: Radiofrequency thermocoagulation (RFT) has been widely used to manage trigeminal neuralgia (TN) refractory to oral medication. Careful selection of patients for managing TN with RFT can decrease morbidity and improve treatment efficacy. OBJECTIVES: The goal of this study was to determine clinical variables related to the treatment outcome in patients with TN undergoing RFT. STUDY DESIGN: Retrospective analysis. SETTING: University hospital in Korea. METHODS: Demographic and clinical

Pathology and Forensic MedicineMedicine
4
Article|43 citations·2016
Korean Version of the painDETECT Questionnaire: A Study for Cultural Adaptation and Validation
Jun Kyung Sung, Jeong‐Hyun Choi, Jinyoung Jeong, Wonjoong Kim, Da Jeong Lee, Sang Chul Lee, Yong Chul Kim, Jee Youn Moon
SJR Q1Pain Practice

OBJECTIVE: The purpose of this study was to adapt the painDETECT Questionnaire (PD-Q) into a Korean version (KPD-Q) and validate it. METHODS: A single-center prospective observational study was performed. During the first phase of the study, linguistic adaptation was carried out to develop the KPD-Q. During the second phase of the study, feasibility, internal consistency, discriminant validity, and concurrent validity were assessed for psychometric validation of the KPD-Q. RESULTS: A total of 23

PhysiologyMedicine
5
Article|37 citations·2012
Analysis of patterns of three-phase bone scintigraphy for patients with complex regional pain syndrome diagnosed using the proposed research criteria (the ‘Budapest Criteria’)
Jee Youn Moon, So Yeon Park, Y.C. Kim, S. C. Lee, Francis Sahngun Nahm, Jae Hun Kim, Hyun‐Chang Kim, Sewoong Oh
SJR Q1British Journal of Anaesthesia
Anesthesiology and Pain MedicineMedicine
6
Article|33 citations·2016
The Effect of Nefopam on Postoperative Fentanyl Consumption: A Randomized, Double-blind Study
Jee Youn Moon, Sang Sik Choi, Shin Young Lee, Mi Kyung Lee, Jung Eun Kim, Ji Eun Lee, So Hyun Lee
SJR Q1The Korean journal of painOA

The concomitant administration of nefopam with fentanyl for postoperative pain management may allow reduction of fentanyl dose, thereby reducing the risk of opioid-related adverse effects.

SurgeryMedicine
7
Article|30 citations·2015
Eugenol Inhibits the GABAA Current in Trigeminal Ganglion Neurons
Sang Hoon Lee, Jee Youn Moon, Sung Jun Jung, Jin Gu Kang, Seung Pyo Choi, Jun Ho Jang
SJR Q1PLoS ONEOA

Eugenol has sedative, antioxidant, anti-inflammatory, and analgesic effects, but also serves as an irritant through the regulation of a different set of ion channels. Activation of gamma aminobutyric acid (GABA) receptors on sensory neurons leads to the stabilization of neuronal excitability but contributes to formalin-induced inflammatory pain. In this study, we examined the effect of eugenol on the GABA-induced current in rat trigeminal ganglia (TG) neurons and in human embryonic kidney (HEK)

Sensory SystemsNeuroscience
8
Article|27 citations·2014
Predictive Factors Associated With Success and Failure for Calmare (Scrambler) Therapy
Jee Youn Moon, Connie Kurihara, Judith P. Beckles, Karen E. Williams, David E. Jamison, Steven P. Cohen
SJR Q1Clinical Journal of Pain

A neuropathic or mixed neuropathic-nociceptive pain condition was associated with a positive treatment outcome. Investigators should consider these findings when developing selection criteria in clinical trials designed to determine the efficacy of Calmare therapy.

Cognitive NeuroscienceNeuroscience
9
Article|26 citations·2018
Addressing Opioid-Related Chemical Coping in Long-Term Opioid Therapy for Chronic Noncancer Pain: A Multicenter, Observational, Cross-Sectional Study
Anyela Marcela Castañeda, Chang-Soon Lee, Yong Chul Kim, Dasom Lee, Jee Youn Moon
SJR Q1Journal of Clinical MedicineOA

Opioid consumption has increased worldwide, which carries the risk of opioid use disorder (OUD). However, the literature on OUD and opioid-related chemical coping (OrCC) in chronic noncancer pain (CNCP) is heterogeneous, with most studies conducted in the United States. We performed a multicenter, observational, cross-sectional study to address OrCC in long-term opioid therapy (LtOT) for CNCP in South Korea. The objectives were to determine the frequency and predictors of OrCC. We included 258 p

Public Health, Environmental and Occupational HealthMedicine
10
Article|26 citations·2015
An exploratory study on the effectiveness of “Calmare therapy” in patients with cancer-related neuropathic pain: A pilot study
Sang Chul Lee, Keun Suk Park, Jee Youn Moon, Eun Jung Kim, Yong Chul Kim, Hye-Jin Seo, Joon Kyung Sung, Da Jeong Lee
SJR Q1European Journal of Oncology Nursing
PhysiologyMedicine
11
Article|26 citations·2017
Does Temperature Increase by Sympathetic Neurolysis Improve Pain in Complex Regional Pain Syndrome? A Retrospective Cohort Study
Sushmitha Dev, Yongjae Yoo, Ho‐Jin Lee, Dong-Ho Kim, Yong Chul Kim, Jee Youn Moon
SJR Q2World Neurosurgery
Anesthesiology and Pain MedicineMedicine
12
Article|20 citations·2017
A Retrospective Study to Evaluate the Effect of Concentration of Hypertonic Saline on Efficacy and Safety of Epidural Adhesiolysis
Eun Joo Choi, Yong Jae Yoo, Pyung Bok Lee, Yong Chul Kim, Sang Chul Lee, Jee Youn Moon
SJR Q1Anesthesia & Analgesia

BACKGROUND: Percutaneous epidural adhesiolysis (PEA) is a minimally invasive procedure that is performed to relieve low back and/or lower limb pain secondary to adhesions or scarring in the epidural space that is refractory to conservative treatment. The optimal concentration of hypertonic saline might be an important factor in the safety and efficacy of PEA. We evaluated differences in the efficacy and safety of 2 concentrations of hypertonic saline (5% and 10%) used in lumbar PEA at our instit

Pathology and Forensic MedicineMedicine
13
Article|18 citations·2018
Usefulness of the Korean Version of the CAGE-Adapted to Include Drugs Combined With Clinical Predictors to Screen for Opioid-Related Aberrant Behavior
Chang-Soon Lee, Dae‐Hyun Kim, Sang-Yoen Park, Sang Chul Lee, Young‐Chul Kim, Jee Youn Moon
SJR Q1Anesthesia & AnalgesiaOA

BACKGROUND: As national opioid consumption in South Korea has soared, well-validated screening tools for opioid use disorder (OUD) have become indispensable. The aims of our study were to evaluate OUD using the Korean version of the CAGE-Adapted to Include Drugs (CAGE-AID) and the CAGE-Opioid (an alternative version of the CAGE-AID), and to investigate clinical predictors that might be useful to screen for OUD in conjunction with the CAGE-AID/Opioid questionnaires. METHODS: A single-center, pros

Public Health, Environmental and Occupational HealthMedicine
14
Article|18 citations·2016
The Effect of Nefopam on Postoperative Fentanyl Consumption: A Randomized, Double-blind Study
문지연, 최상식, 이신영, 이미경, 김정은, 이지은, 이소현

Background: Nefopam is a non-opioid, non-steroidal, centrally acting analgesic drug. The concomitant use of opioids and nefopam is believed to have many advantages over the administration of opioids alone for postoperative pain management. We conducted a randomized, double-blind study to determine the fentanyl- sparing effect of co-administration of nefopam with fentanyl for postoperative pain management via patient controlled analgesia (PCA). Methods: Ninety female patients who underwent laparo

15
Article|17 citations·2013
An Alternative Distal Approach for the Lumbar Medial Branch Radiofrequency Denervation
Jee Youn Moon, Pyung Bok Lee, Yong Chul Kim, Seung Pyo Choi, Woo Seog Sim
SJR Q1Anesthesia & Analgesia

Patients who underwent LMBRFD by the tunnel vision or distal approaches showed significant pain relief at the 6-month follow-up. Less periprocedural pain was reported in the distal approach group. We consider that the distal approach provides an improved option for LMBRFD.

Pathology and Forensic MedicineMedicine

Research Areas

Anesthesiology and Pain MedicinePathology and Forensic MedicineSurgeryPharmacologyPhysiologyPsychiatry and Mental health

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