Jeong A Tak
Hanyang University · Biochemistry, Genetics and Molecular Biology
About the Lab
Professor Jeong A Tak's research lab specializes in the design and synthesis of novel metal-based complexes and natural product derivatives for applications in renewable energy and cancer therapy. The lab focuses on developing ruthenium(II) sensitizers with tailored ligands for dye-sensitized solar cells (DSSCs), emphasizing molecular engineering to enhance light-harvesting and photostability. Concurrently, the lab investigates artemisinin derivatives and their oligomeric forms for potent antitumor activity, particularly against a range of cancer cell lines. The interdisciplinary approach combines coordination chemistry, medicinal chemistry, and materials science to advance sustainable energy solutions and targeted cancer therapeutics.
Research Overview
Research Output Trend
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Selected Papers
11BACKGROUND: Artemisinin is of special biological interest because of its outstanding antimalarial activity. Recently, it was reported that artemisinin has antitumor activity. Its derivatives, artesunate, arteether, and artemeter, also have antitumor activity against melanoma, breast, ovarian, prostate, CNS, and renal cancer cell lines. Recently, monomer, dimer, and trimer derivatives were synthesized from deoxoartemisinin, and the dimers and the trimers were found to have much more potent antitu
Heteroleptic Ru( II ) complexes were designed based on 4,4′‐bis(( E )‐styryl)‐2,2′‐bipyridine (bsbpy) as an ancillary ligand for dye‐sensitized solar cells ( DSSC s), and those Ru( II ) sensitizers, [Ru(L)(bsbpy)( NCS ) 2 ][ TBA ] ( TBA ; tetrabutylammonium), were synthesized according to a typical one‐pot reaction of [RuCl 2 ( p ‐cymene)] 2 with the corresponding anchoring ligands (where L = 4,4′‐dicarboxy‐2,2′‐bipyridine (dcbpy), 4,4′‐bis(( E )‐carboxyvinyl)‐2,2′‐bipyridine (dcvbpy), 4,7‐dicar
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Research Areas
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