Jihyeon Yeom
Korea Advanced Institute of Science and Technology · Materials Science
About the Lab
Professor Jihyeon Yeom's research lab specializes in the design and functionalization of advanced nanomaterials with tailored chiral, optical, and mechanical properties for biomedical and technological applications. The lab focuses on photon-to-matter chirality transfer, chiral nanomaterials, and surface engineering to enable smart biomaterials that interact selectively with cells and proteins. Key research directions include the development of chiral supraparticles, stimuli-responsive gels, and biocompatible quantum dot systems for medical data encoding and diagnostics.
Research Overview
Research Output Trend
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Selected Papers
15Surface modification is one of the most important techniques in modern science and engineering. The facile introduction of a wide variety of desired properties onto virtually any material surface is an ultimate goal in surface chemistry. To achieve this goal, the incorporation of structurally diverse molecules onto any material surface is an essential capability for ideal surface modification. Here, we present a general strategy of surface modification, in which many diverse surfaces can be func
nanoparticles with chiral distortions of the crystal lattices exhibited chiroptical activity in the visible range that was 10 times as strong as that of nonparamagnetic nanoparticles of comparable size. Transparency of the nanoparticle gels to circularly polarized light beams in the ultraviolet range was reversibly modulated by magnetic fields. These phenomena were also observed for other nanoscale metal oxides with lattice distortions from imprinted amino acids and other chiral ligands. The lar
Interconnectivity of components in three-dimensional networks (3DNs) is essential for stress transfer in hydrogels, aerogels, and composites. Entanglement of nanoscale components in the network relies on weak short-range intermolecular interactions. The intrinsic stiffness and rod-like geometry of nanoscale components limit the cohesive energy of the physical crosslinks in 3DN materials. Nature realizes networked gels differently using components with extensive branching. Branched aramid nanofib
Chirality is ubiquitous in nature and hard-wired into every biological system. Despite the prevalence of chirality in biological systems, controlling biomaterial chirality to influence interactions with cells has only recently been explored. Chiral-engineered supraparticles (SPs) that interact differentially with cells and proteins depending on their handedness are presented. SPs coordinated with d-chirality demonstrate greater than threefold enhanced cell membrane penetration in breast, cervica
Photon-to-matter chirality transfer offers both simplicity and universality to chiral synthesis, but its efficiency is typically low for organic compounds. Besides the fundamental importance of this process relevant for understanding the origin of homochirality on Earth, new pathways for imposing chiral bias during chemical process are essential for a variety of technologies from medicine to informatics. The strong optical activity of inorganic nanoparticles (NPs) affords photosynthetic routes t
Accurate medical recordkeeping is a major challenge in many low-resource settings where well-maintained centralized databases do not exist, contributing to 1.5 million vaccine-preventable deaths annually. Here, we present an approach to encode medical history on a patient using the spatial distribution of biocompatible, near-infrared quantum dots (NIR QDs) in the dermis. QDs are invisible to the naked eye yet detectable when exposed to NIR light. QDs with a copper indium selenide core and alumin
Nanoscale pyrite FeS 2 is considered to be one of few potentially transformative materials for photovoltaics capable of bridging the cost/performance gap of solar batteries. It also holds promise for energy storage applications as the material for high-performance cathodes. Despite prospects, the synthesis of FeS 2 nanostructures and diversity of their geometries has been hardly studied. Moreover, the state-of-the-art aqueous dispersions of nanoscale pyrite, which have special significance for s
A plant-inspired, amine-containing small phenol molecule, 5-pyrogallol 2-aminoethane (PAE), can perform surface functionalization in a material-independent manner. The co-existence of primary amine and pyrogallol moieties are essential for the material-independent coating ability of PAE. The multi-functionality of the PAE-mediated surface chemistry will be useful in many areas including biomedical applications, drug delivery, and the development of energy storage devices. As a service to our aut
Conspectus Chirality is ubiquitous in the universe and in living creatures over detectable length scales from the subatomic to the galactic, as exemplified in the two extremes by subatomic particles (neutrinos) and spiral galaxies. Between them are living creatures that display multiple levels of chirality emerging from hierarchically assembled asymmetric building blocks. Not too far from the bottom of this pyramid are the foundational building blocks with chiral atomic centers on sp 3 carbon at
Research on chiral nanomaterials (NMs) has grown radically with a rapid increase in the number of publications over the past decade. It has attracted a large number of scientists in various fields predominantly because of the emergence of unprecedented electric, optical, and magnetic properties when chirality arises in NMs. For applications, it is particularly informative and fascinating to investigate how chiral NMs interact with electromagnetic waves and magnetic fields, depending on their int
Chiral nanomaterials provide a rich platform for versatile applications. Tuning the wavelength of polarization rotation maxima in the broad range including short-wave infrared (SWIR) is a promising candidate for infrared neural stimulation, imaging, and nanothermometry. However, the majority of previously developed chiral nanomaterials reveal the optical activity in a relatively shorter wavelength range (ultraviolet-visible, UV-vis), not in SWIR. Here, we demonstrate a versatile method to synthe
Chirality, the property whereby an object or a system cannot be superimposed on its mirror image, prevails amongst nature over various scales. Especially in biology, numerous chiral building blocks and chiral-specific interactions are involved in many essential biological activities. Despite the prevalence of chirality in nature, it has been no longer than 70 years since the mechanisms of chiral-specific interactions drew scientific attention and began to be studied. Owing to the advent of chira
ADVERTISEMENT RETURN TO ISSUEViewpointNEXTAtomic Chirality and a Materials RevolutionJihyeon Yeom*Jihyeon YeomDepartment of Materials Science and Engineering, Department of Biological Sciences, KAIST Institute of Health Science and Technology, Korea Advanced Science and Technology (KAIST), Deajeon 34141, Republic of Korea*Email: [email protected]More by Jihyeon YeomView Biographyhttps://orcid.org/0000-0002-3032-8301Cite this: Acc. Mater. Res. 2021, 2, 7, 471–476Publication Date (Web):May 27, 202
Research Areas
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