Jong Mo Seo

There has been no report about hereditary and clinical features of retinitis pigmentosa (RP) in Koreans. To evaluate these, data were collected from 365 RP patients including age, gender, visual acuity (VA), spherical equivalent (SE) of refractive errors,funduscopic findings, color vision test, visual field score (VFS) obtained from Goldmann perimetry, and the inheritance patterns from pedigrees. Simplex RP was the most common inheritance pattern (61.9%); followed by autosomal recessive RP (17.3

Saemangeum Reservoir in South Korea is an estuarine system enclosed by a dyke construction, where seawater inflow and retained water outflow are managed by the opening/closing of sluice gates installed in the southern part of the dyke. An exchange of the reservoir water can cause spatiotemporal fluctuations in the salinity and trophic state, which are major drivers determining variation in the composition of biological communities in estuarine systems. Here, we investigated the seasonal and spat

Abstract Risk analyses for invasive species often assume that the characteristics of future invaders will resemble those already successful, but these features may change. Here, we use data from more than 3,500 fish sampling events, sequencing of mitochondrial and nuclear genes and analyses of several traits describing non‐native fish to describe the irruption and rapid expansion of non‐native loaches in Catalonia, north‐east Iberian Peninsula, and framing this surge in the knowledge of previous

목적: 각막굴절교정 렌즈 착용이 근시진행억제에 미치는 영향을 알아보고자 하였다. 대상과 방법: 근시 및 난시를 대상으로 각막굴절교정 렌즈를 1년 이상 착용한 144안을 착용 전과 렌즈착용을 중지한 지 2-4주 후에조절마비 굴절검사 및 각막곡률반경을 측정하여 굴절력의 차이를 비교하였다. 근시 및 난시를 안경으로 교정한 대상을 대조군으로190안을 선정하여 렌즈착용 군과 비교하였다. 나이, 근시 및 난시와의 관계, 근시 및 난시의 진행과 착용시간과의 연관성을 각각 비교하였다. 결과: 각막굴절교정 렌즈를 사용한 대상의 구면렌즈대응치은 평균 -3.36 ± 1.96D였으며, 난시는 평균 -0.86 ± 0.72D, 기간은 평균3.41 ± 1.5년이었고 나이는 평균 10.31 ± 2.37년이었다. 렌즈를 착용한 경우의 1년간 근시진행은 평균 0.25 ± 0.31D로 대조군 0.62± 0.39D와 유의한 차이가 있었고(t-test, p＜0.01), 난시진행도 렌즈를 착용한 군이 평균 0.06 ± 0

Despite being naturally fishless, the widespread introduction of trout and minnows is threatening the conservation of high mountain lakes all over the world. Previous studies have reported that amphibians quickly disappear after trout introduction, followed by many conspicuous invertebrates. Here, we have studied the effects of minnows versus trout on the littoral macroinvertebrate community of 54 high mountain lakes from the Pyrenees, covering a gradient of environmental characteristics. The re

Smartphone technology has spread rapidly around the globe. According to a report released by the Korea Information Society Development Institute, about 95% of Koreans aged more than 30 years old owned smartphones. Recently, blood pressure (BP) measurement using a photoplethysmography-based smartphone algorithm paired with the smartwatch is continuously evolving. In this document, the Korean Society of Hypertension intends to remark the current results of smartphone / smartwatch-based BP measurem

Silicon-micromachined retinal tacks were developed for the xation of the epiretinal-type retina-stimulating microelectrodearray. Silicon retinal tacks were fabricated by using the silicon on insulator (SOI) process, a method of releasing silicon structuresin a SOI wafer. The dimensions of the retinal tack were substantially smaller than those of the conventional titanium tack, at 1.5 mmlong, 150l m wide, and 150l m thick. To enhance the durability and biocompatibility of the retinal tack, 3l m-t

Background Cuffless blood pressure (BP) measurement, enabled by recent advances in wearable devices, allows for BP monitoring in daily life. This study aims to evaluate the feasibility, cresdence, and usefulness of cuffless BP monitoring through a population survey. Methods During the "Daily BP Measurement with Your Galaxy Watch" campaign held by the Korean Society of Hypertension, participants were asked to share their experiences with cuffless BP measurement using a smartwatch application thro

Brain is complex organ composed of numerous glial cellsand neurons to convey information using chemical andelectrical signals. Neural interface technology using theelectrical brain signals has attracted great attention for theclinical and experimental applications. Electrode as theneural interface is the most important part in stimulatingneural cells or recording neural activities. In this paper, weprovide an overview of electrodes for recording the electricalbrain signal. The noninvasive electr

The gold-spotted pond frog (Pelophylax chosenicus) is an endangered amphibian species in South Korea. In order to obtain ecological information regarding the gold-spotted pond frog’s habitat environment and biological interactions, we applied stable isotope analysis to quantify the ecological niche space (ENS) of frogs including black-spotted pond frogs (P. nigromaculatus) and bullfrogs (Lithobates catesbeianus) within the food web of two different habitats—an ecological wetland park and a rice

Sacral nerve stimulation (SNS) is a therapeutic medical procedure that stimulates the sacral nerve using an electrode inserted near the sacral nerve to treat the conditions of overactive bladder and fecal incontinence. The primary challenge in the SNS procedure is that the physician inserts a needle to place an electrode through the narrow structure of the sacrum while relying on fluoroscopic images. We developed a navigation system which relies on an off-the-shelf electromagnetic tracking devic

Purpose Using 18F- fluorodeoxyglucose positron emission tomography (FDG PET), we aimed to assess the cortical areas activated by light and electrical stimuli in rabbits and to determine the nature of the electrically evoked visual perception by comparing the 2 activated cortical images. Methods Three adult white rabbits were used, and 5 18F -FDG PET scans were performed on 5 different days for each rabbit: a resting image, 2 light stimulation images, and 2electrical retinal stimulation images by

목적: 초고선명 화질의 화면 시청이 눈깜박임 양상에 미치는 영향을 알아보고, 건성안과 정상안에서 눈깜박임이 어떻게 다른지 비교하고자 하였다. 대상과 방법: 만 13-69세 남녀 59명(118안)을 대상으로 초고선명 텔레비전의 채도가 높고 움직임이 큰 영상을 10분 동안 시청하도록 하였다. 시청 전후 각각 최대교정시력, 자동굴절검사, 세극등검사로 평가한 눈물막 파괴시간, 각막염색 정도, 결막 충혈 정도를 조사하였고, 이와 함께 눈의 피로도 또는 건성안 증상 평가를 위한 설문조사를 함께 시행하였다. 눈물막 파괴시간이 양안 중 하나라도 5초 이하이거나 결막 충혈이 경도 이상으로 있거나, 각막미란이 뚜렷하게 있을 때를 건성안으로 정의하였고, 시청 초반과 후반에 각각 눈깜박임 횟수 및 시간 등을 영상 분석을 통해 측정하였다. 결과: 정상안군에서 영상을 시청한 후 평균 눈물막 파괴시간이 감소하고(p<0.001), 평균 각막미란 정도도 심해졌지만(p=0.023), 피검사자가 느끼는 주관적 눈의

목적 : 망막색소상피에 대한 자외선, 산화, 저산소 손상에서 Ginkgo biloba extract (EGb)의 세포사멸에 대한 보호효과를 알아보고자 하였다. 대상과 방법 : 배양망막색소상피에 EGb, Vitamin E, 홍삼을 손상 자극 전에 투여하고 자외선 손상, 산화 손상, 저산소 배양 손상을 주었다. 일정 시간 후에 생존 세포수를 결정하고, apoptosis의 정도를 결정하여 이들 약물의 효과를 비교하였다. 결과 : UVB 조사 전에 EGb와 Vitamin E를 투여하였을 때, 투여하지 않은 경우보다 세포 생존율이 높았고, 최대 생존율에 대한 EGb와 Vitamin E의 차이는 없었다. 산화 손상 1시간 전에 EGb를 투여하였을 때 세포 생존율이 높아졌다. 저산소 손상에 대한 최대 약물 보호 효과는 EGb, Vitamin E, 홍삼 중 EGb가 가장 좋았다. 결론 : EGb는 배양망막색소상피에 대한 손상으로부터 세포 사멸을 억제하는 작용이 있으며, 병인에서 망막색소상피세포의