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Jong Seo Lee

Sungkyunkwan University · Medicine

About the Lab

Professor Jong Seo Lee's research lab specializes in spinal deformity and spinal surgery, with a strong focus on sagittal spinal alignment, proximal junctional failure (PJF), and long-segment spinal instrumentation. The lab investigates biomechanical and clinical risk factors for complications such as proximal junctional kyphosis (PJK) and nonunion at the lumbo-sacral junction, particularly in adult spinal deformity (ASD) and degenerative lumbar conditions. Their work emphasizes optimizing surgical outcomes through individualized spinal balance restoration, implant fixation strategies, and motion-preserving techniques like lumbar total disc replacement (TDR). The lab integrates radiographic analysis, survivorship modeling, and long-term clinical follow-up to guide evidence-based surgical decision-making.

spinal deformityproximal junctional failuresagittal alignmentlumbar disc replacementspinal instrumentation

Research Overview

Papers
293
Total Citations
4,435
Papers (5y)
64
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
64total
2022
2023
2024
2025
2026
Citations per year (5y)
303total
20222023202420252026

Selected Papers

15
1
Article|190 citations·2016
Different Risk Factors of Proximal Junctional Kyphosis and Proximal Junctional Failure Following Long Instrumented Fusion to the Sacrum for Adult Spinal Deformity: Survivorship Analysis of 160 Patients
Se‐Jun Park, Chong-Suh Lee, Sung-Soo Chung, Juneyoung Lee, Sang-Soo Kang, Se-Hwan Park
SJR Q1Neurosurgery

Background: The failure modes, time to development, and clinical relevance are known to differ between proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). However, there are no reports that study the risk factors of PJK and PJF separately. Objective: The aim of this study was to investigate the risk factors for PJK and PJF separately. Methods: A retrospective study of 160 consecutive patients who underwent a long instrumented fusion to the sacrum for adult spinal deformity

SurgeryMedicine
2
Article|157 citations·2011
Normal Patterns of Sagittal Alignment of the Spine in Young Adults Radiological Analysis in a Korean Population
Chong Suh Lee, Sung Soo Chung, Kyung Chung Kang, Se Jun Park, Seong Kee Shin
SJR Q1Spine

The patterns of sagittal alignment could be classified into three types showing that the spinal balance becomes more negative, the lumbar inclination and TLJA increase, the SS and pelvic incidence decrease, and lumbar lordotic curves becomes shorter as the patterns of sagittal curvature move toward type 3. This classification in young adults should be considered individually as a reference for surgeons aiming to restore the lumbar lordosis and sagittal alignment in degenerative lumbar fusion sur

SurgeryMedicine
3
Article|108 citations·2014
In vivo study of chitosan-natural nano hydroxyapatite scaffolds for bone tissue regeneration
Jong Seo Lee, Sang Dae Baek, Jayachandran Venkatesan, Ira Bhatnagar, Hee Kyung Chang, Hui Taek Kim, Se‐Kwon Kim
SJR Q1International Journal of Biological Macromolecules
Biomedical EngineeringEngineering
5
Article|70 citations·2012
Metastatic Spinal Tumor
Chong-Suh Lee, Chul-Hee Jung
SJR Q1Asian Spine JournalOA

In accordance with extending survival periods of cancer patients, number of consecutively developing metastatic spinal tumor is also increasing. There have been improvements in the treatment results of metastatic spine tumor by virtue of the developments in diagnostic radiology, chemotherapy, adjuvant treatment, operative device and technique, discrete preoperative plan, and standardized operation. Accordingly, surgical indication has also increased. Clinically, in case of metastatic spine tumor

SurgeryMedicine
6
Article|60 citations·2013
The effect of simulated knee flexion on sagittal spinal alignment: novel interpretation of spinopelvic alignment
Chong Suh Lee, Se-Jun Park, Sung Soo Chung, Keun Ho Lee
SJR Q1European Spine Journal
SurgeryMedicine
7
Article|57 citations·2019
Rod fracture and related factors after total en bloc spondylectomy
Se‐Jun Park, Chong-Suh Lee, Bong‐Soon Chang, Young-Hoon Kim, Hyoungmin Kim, Sang-Il Kim, Sam-Yeol Chang
SJR Q1The Spine Journal
SurgeryMedicine
8
Article|56 citations·2010
Critical Length of Fusion Requiring Additional Fixation to Prevent Nonunion of the Lumbosacral Junction
Chong-Suh Lee, Sung Soo Chung, Sung Woo Choi, Jae Wook Yu, Min Su Sohn
SJR Q1Spine

The risk of nonunion at the L-S junction was found to increase significantly for more than 3 levels of fusion. We advise that additional stronger fixation is needed in such cases.

Pathology and Forensic MedicineMedicine
9
Article|56 citations·2019
Should Thoracolumbar Junction Be Always Avoided as Upper Instrumented Vertebra in Long Instrumented Fusion for Adult Spinal Deformity?
Se‐Jun Park, Chong-Suh Lee, Jin-Sung Park, Kyung-Jun Lee
SJR Q1Spine

STUDY DESIGN: Retrospective study. OBJECTIVE: The aim of this study was to investigate the risk factors for proximal junctional failure (PJF) following long instrumented fusion stopping at thoracolumbar junction (TLJ) in adult spinal deformity (ASD) and to determine which cases are suitable for TLJ stop without increasing the risk for PJF. SUMMARY OF BACKGROUND DATA: PJF following long fusion for ASD is a well-recognized complication that negatively affects clinical outcomes. Generally, the uppe

SurgeryMedicine
10
Article|52 citations·2006
The Effect of Lumbar Total Disc Replacement on the Spinopelvic Alignment and Range of Motion of the Lumbar Spine
Sung Soo Chung, Chong Suh Lee, Chang Seok Kang, Sang Hyun Kim
Journal of Spinal Disorders & Techniques

A lumbar total disc replacement (TDR) is a type of motion-preserving surgery, which aims to restore and maintain the normal range of motion (ROM) and the sagittal balance of the spine. However, little is known regarding how the spinopelvic alignment and ROM of the lumbar spine are influenced by the lumbar TDR with ProDisc. This study retrospectively analyzed the sagittal alignment and ROM of the lumbar spine in 26 consecutive patients who had undergone the TDR with ProDisc with a minimum follow-

Pathology and Forensic MedicineMedicine
11
Article|48 citations·2017
Spectrum of mutations in leiomyosarcomas identified by clinical targeted next-generation sequencing
Jong Seo Lee, Naomi Yoo, Ian S. Hagemann, John D. Pfeifer, Catherine E. Cottrell, Haley Abel, Eric J. Duncavage
SJR Q1Experimental and Molecular Pathology
Pulmonary and Respiratory MedicineMedicine
12
Article|47 citations·2022
Validation of Age-adjusted Ideal Sagittal Alignment in Terms of Proximal Junctional Failure and Clinical Outcomes in Adult Spinal Deformity
Se‐Jun Park, Chong-Suh Lee, Byeong-Jik Kang, Tae Soo Shin, Il Su Kim, Jin-Sung Park, Keun‐Ho Lee, Dae Hun Shin
SJR Q1Spine

STUDY DESIGN: Retrospective study. OBJECTIVE: To validate the age-adjusted ideal sagittal alignment in terms of proximal junctional failure (PJF) and clinical outcomes. SUMMARY OF BACKGROUND: It is reported that optimal sagittal correction with regard to the age-adjusted ideal sagittal alignment reduces the risk of PJF development. However, few studies have validated this concept. The age-considered optimal correction is likely to be undercorrection in terms of conventional surgical target, such

SurgeryMedicine
13
Article|43 citations·2013
Simple prediction method of lumbar lordosis for planning of lumbar corrective surgery: radiological analysis in a Korean population
Chong Suh Lee, Sung Soo Chung, Se Jun Park, Dong Min Kim, Seong Kee Shin
SJR Q1European Spine JournalOA
SurgeryMedicine
14
Article|42 citations·2016
Long-Term Outcomes Following Lumbar Total Disc Replacement Using ProDisc-II
Se‐Jun Park, Chong-Suh Lee, Sung-Soo Chung, Keun‐Ho Lee, Wan-Seok Kim, Juneyoung Lee
SJR Q1Spine

4.

Pathology and Forensic MedicineMedicine
15
Article|40 citations·2009
Correlation of Pelvic Parameters with Isthmic Spondylolisthesis
Sung Kyun Oh, Sung Soo Chung, Chong-Suh Lee
SJR Q1Asian Spine JournalOA

STUDY DESIGN: A retrospective radiological evaluation. PURPOSE: To verify that PI is related with progression of IS as well as development of IS and to assess the differences of pelvic parameters between the L4 & L5 IS, as well as between single & two level IS. OVERVIEW OF LITERATURE: High pelvic incidence (PI) has been known to be related with development of IS. However, the previous studies were limited to just L5 spondylolisthesis or there was no differentiation between L4 & L5 spondylolisthe

SurgeryMedicine

Research Areas

SurgeryPathology and Forensic MedicineBiomedical EngineeringMolecular BiologyRheumatologyGenetics

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