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Jong-Tae Cha

Yonsei University · Medicine

About the Lab

Professor Jong-Tae Cha's research lab specializes in nuclear medicine and molecular imaging, focusing on the clinical application of PET/CT and SPECT/CT in oncology. The lab investigates metabolic and perfusion biomarkers—such as SUVmax, Hounsfield units (HU), and thyroglobulin levels—to improve cancer risk stratification, treatment planning, and prognostic prediction in thyroid, breast, and hepatocellular carcinomas. Key research directions include optimizing I-131 radioiodine therapy using serum thyroglobulin and imaging parameters, evaluating tumor metabolism and vascularity in HCC, and assessing physiological FDG uptake in transposed ovaries to guide radiation oncology. The lab emphasizes translational research that bridges molecular imaging with clinical decision-making.

PET/CTthyroid cancerbreast cancermolecular imagingtumor metabolism

Research Overview

Papers
36
Total Citations
227
Papers (5y)
10
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
10total
2021
2022
2023
2024
2025
Citations per year (5y)
12total
20212022202320242025

Selected Papers

15
1
Article|107 citations·1991
Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain
Sharin Y. Sakurai, Jongtae Cha, John B. Penney, A. Byron Young
SJR Q2NeuroscienceOA
Cellular and Molecular NeuroscienceNeuroscience
2
Article|51 citations·2007
Glutamate receptor abnormalities in the YAC128 transgenic mouse model of Huntington’s disease
Caroline Benn, Elizabeth Slow, Laurie Farrell, Rona K. Graham, Yu Deng, Michael R. Hayden, Jongtae Cha
SJR Q2NeuroscienceOA
Cellular and Molecular NeuroscienceNeuroscience
3
Article|14 citations·2017
Evaluation of 18F-FDG PET/CT Parameters for Detection of Lymph Node Metastasis in Cutaneous Melanoma
Jongtae Cha, Soyoung Kim, Jiyoung Wang, Mijin Yun, Arthur Cho
SJR Q2Nuclear Medicine and Molecular ImagingOA
OncologyMedicine
4
Article|13 citations·2014
Correlation Analysis and Prognostic Impact of 18F-FDG PET and Excision Repair Cross-Complementation Group 1 (ERCC-1) Expression in Non-Small Cell Lung Cancer
Yong Hyu Jeong, Choong‐kun Lee, Kwanhyeong Jo, Sang Hyun Hwang, Jongtae Cha, Jeong Won Lee, Mijin Yun, Arthur Cho
SJR Q2Nuclear Medicine and Molecular ImagingOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
5
Article|8 citations·2018
A hierarchical prognostic model for risk stratification in patients with early breast cancer according to 18F‐fludeoxyglucose uptake and clinicopathological parameters
Jongtae Cha, Hyung Seok Park, Dongwoo Kim, Hyun Jeong Kim, Min Jung Kim, Young Up Cho, Mijin Yun
SJR Q1Cancer MedicineOA

F-fludeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT) for recurrence-free survival (RFS) in patients with early breast cancer who underwent surgery without neoadjuvant chemotherapy. A total of 524 patients with early breast cancer were included. The Cox proportional hazards model was used with clinicopathological variables and maximum standardized uptake value (SUVmax) on PET/CT. After classification and regression tree (CART) modeling, RFS curves were estim

Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|8 citations·2015
Risk Stratification of Thyroid Incidentalomas Found on PET/CT: The Value of Iodine Content on Noncontrast Computed Tomography
Dongwoo Kim, Sang Hyun Hwang, Jongtae Cha, Kwanhyeong Jo, Narae Lee, Mijin Yun
SJR Q1ThyroidOA

BACKGROUND: The Hounsfield unit (HU) ratio of thyroid nodules was assessed compared to the contralateral thyroid lobe on noncontrast computed tomography (CT) to stratify further the risk of malignancy in thyroid incidentalomas found on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/CT (PET/CT). METHODS: This retrospective analysis included 82 patients who had thyroid incidentalomas on PET/CT in 2011. On PET/CT, the maximal standardized uptake value ratios of the thyroid nodule c

Endocrinology, Diabetes and MetabolismMedicine
7
Article|5 citations·2015
A Comparison Study of Esophageal Findings on 18F-FDG PET/CT and Esophagogastroduodenoscopy
Kwanhyeong Jo, Soyoung Kim, Jongtae Cha, Sang Hyun Hwang, Narae Lee, Mijin Yun, Won Jun Kang
SJR Q2Nuclear Medicine and Molecular ImagingOA
SurgeryMedicine
8
Article|5 citations·2023
Does high [18F]FDG uptake always mean poor prognosis? Colon cancer with high-level microsatellite instability is associated with high [18F]FDG uptake on PET/CT
Jongtae Cha, Honsoul Kim, Hye Jung Shin, Myeongjee Lee, Seowoong Jun, Won Jun Kang, Arthur Cho
SJR Q1European Radiology
Pathology and Forensic MedicineMedicine
9
Article|5 citations·2024
Correlation between remnant thyroid gland I-131 uptake and serum thyroglobulin levels: can we rely on I-131 whole body scans?
Sang Hyun Hwang, Kwanhyeong Jo, Jongtae Cha, Chun Goo Kang, Jiyoung Wang, Hojin Cho, Won Jun Kang, Arthur Cho
SJR Q1Cancer ImagingOA

BACKGROUND: I-131 treatment (RAI) decision relies heavily on serum thyroglobulin (Tg) levels, as higher Tg levels are assumed to be correlated with higher I-131 uptake. Tg elevation, negative iodine scintigraphy (TENIS) definition is becoming more clinically relevant as alternative treatment methods are available. This study examined the correlation between Tg levels with I-131 uptake in remnant thyroid gland to evaluate the reliability of serum Tg levels in predicting I-131 uptake. METHODS: Fro

Endocrinology, Diabetes and MetabolismMedicine
10
Article|2 citations·2008
Poster 24: Expert Treatment Preferences for the Motor, Mood, and Behavioral Symptoms of Huntington's Disease
LaVonne Goodman, Jongtae Cha, Peter G. Como
SJR Q1Neurotherapeutics
Cellular and Molecular NeuroscienceNeuroscience
11
Article|2 citations·2022
Usefulness and potential pitfalls of pre-operative PET-CT in patients with endometrial cancer undergoing one- and two-step sentinel lymph node mapping: Do negative findings on PET-CT negativity really indicate node negativity?
Yoo‐Na Kim, Dahye Lee, Jongtae Cha, Won Jun Kang, Yong Jae Lee, Jung‐Yun Lee, Eun Ji Nam, Sunghoon Kim, Young Tae Kim, Sang Wun Kim, Sang Wun Kim, Sang Wun Kim
SJR Q1Gynecologic OncologyOA
Obstetrics and GynecologyMedicine
12
Article|2 citations·2009
Effect of metformin on osteoclastogenesis stimulated by bone resorption inducing factors
Eun‐Jung Bak, M. Kim, H. Park, Sunah Kim, Sunah Kim, Jongtae Cha, Yun‐Jung Yoo
SJR Q1Bone
Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
Article|2 citations·2015
Correlation of tumor size and metabolism with perfusion in hepatocellular carcinoma using dynamic contrast enhanced CT and F-18 FDG PET-CT
Sang Hyun Hwang, Jongtae Cha, Kwanhyeong Jo, Yong Hyu Jeong, Hyun Jeong Kim, Arthur Cho, Won Jun Kang, Mijin Yun

1330 Objectives The purpose of this study was to evaluate the correlation of tumor size and metabolism with perfusion in hepatocellular carcinoma (HCC) using dynamic contrast enhanced CT (DCE-CT) and F-18 FDG PET-CT. Methods From April 2008 to July 2013, we retrospectively enrolled 77 patients diagnosed HCC (59 male, 18 female, mean age 56.8 ± 10.4 years old) who underwent dynamic contrast enhance CT and F-18 FDG PET-CT for preoperative staging. Tumor metabolism was evaluated by maximum standard

Radiology, Nuclear Medicine and ImagingMedicine
14
Article|1 citations·2015
Prediction and determination of optimal SUV cutoff values for axillary lymph node metastases (ALNM) on PET/CT in patients with breast cancer.
Jongtae Cha, Sang Hyun Hwang, Kwanhyeong Jo, Yong Hyu Jeong, Hyun Jeong Kim, Arthur Cho, Won Jun Kang, Mijin Yun
Radiology, Nuclear Medicine and ImagingMedicine
15
Book Chapter|1 citations·2009
Triplicate Repeats: Huntington’s disease
Jongtae Cha, Kimberly B. Kegel
Elsevier eBooks
Cellular and Molecular NeuroscienceNeuroscience

Research Areas

Radiology, Nuclear Medicine and ImagingCellular and Molecular NeuroscienceCancer ResearchPulmonary and Respiratory MedicineEndocrinology, Diabetes and MetabolismPathology and Forensic Medicine

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