Jong-Tae Cha
Yonsei University · Medicine
About the Lab
Professor Jong-Tae Cha's research lab specializes in nuclear medicine and molecular imaging, focusing on the clinical application of PET/CT and SPECT/CT in oncology. The lab investigates metabolic and perfusion biomarkers—such as SUVmax, Hounsfield units (HU), and thyroglobulin levels—to improve cancer risk stratification, treatment planning, and prognostic prediction in thyroid, breast, and hepatocellular carcinomas. Key research directions include optimizing I-131 radioiodine therapy using serum thyroglobulin and imaging parameters, evaluating tumor metabolism and vascularity in HCC, and assessing physiological FDG uptake in transposed ovaries to guide radiation oncology. The lab emphasizes translational research that bridges molecular imaging with clinical decision-making.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15F-fludeoxyglucose (FDG) uptake on positron emission tomography/computed tomography (PET/CT) for recurrence-free survival (RFS) in patients with early breast cancer who underwent surgery without neoadjuvant chemotherapy. A total of 524 patients with early breast cancer were included. The Cox proportional hazards model was used with clinicopathological variables and maximum standardized uptake value (SUVmax) on PET/CT. After classification and regression tree (CART) modeling, RFS curves were estim
BACKGROUND: The Hounsfield unit (HU) ratio of thyroid nodules was assessed compared to the contralateral thyroid lobe on noncontrast computed tomography (CT) to stratify further the risk of malignancy in thyroid incidentalomas found on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/CT (PET/CT). METHODS: This retrospective analysis included 82 patients who had thyroid incidentalomas on PET/CT in 2011. On PET/CT, the maximal standardized uptake value ratios of the thyroid nodule c
BACKGROUND: I-131 treatment (RAI) decision relies heavily on serum thyroglobulin (Tg) levels, as higher Tg levels are assumed to be correlated with higher I-131 uptake. Tg elevation, negative iodine scintigraphy (TENIS) definition is becoming more clinically relevant as alternative treatment methods are available. This study examined the correlation between Tg levels with I-131 uptake in remnant thyroid gland to evaluate the reliability of serum Tg levels in predicting I-131 uptake. METHODS: Fro
1330 Objectives The purpose of this study was to evaluate the correlation of tumor size and metabolism with perfusion in hepatocellular carcinoma (HCC) using dynamic contrast enhanced CT (DCE-CT) and F-18 FDG PET-CT. Methods From April 2008 to July 2013, we retrospectively enrolled 77 patients diagnosed HCC (59 male, 18 female, mean age 56.8 ± 10.4 years old) who underwent dynamic contrast enhance CT and F-18 FDG PET-CT for preoperative staging. Tumor metabolism was evaluated by maximum standard
Research Areas
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