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Joongyub Lee

Seoul National University · Medicine

About the Lab

Professor Joongyub Lee's research lab focuses on cerebrovascular diseases, particularly moyamoya disease (MMD), with an emphasis on surgical outcomes, long-term prognosis, and associated systemic conditions such as hypertension. The lab also investigates clinical management strategies in renal replacement therapy, especially incremental peritoneal dialysis for preserving residual renal function. Additionally, the lab contributes to clinical epidemiology and evidence-based medicine by evaluating study quality and bias in medical research. Their work bridges pediatric neurosurgery, nephrology, and health services research through rigorous retrospective and observational studies in single-center cohorts.

moyamoya diseaseperitoneal dialysishypertensionclinical researchevidence-based medicine

Research Overview

Papers
268
Total Citations
5,454
Papers (5y)
59
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
59total
2022
2023
2024
2025
2026
Citations per year (5y)
228total
20222023202420252026

Selected Papers

15
1
Article|215 citations·2010
Pediatric moyamoya disease: An analysis of 410 consecutive cases
Seung‐Ki Kim, Byung‐Kyu Cho, Ji Hoon Phi, Ji Yeoun Lee, Jong‐Hee Chae, Ki Joong Kim, Yong‐Seung Hwang, I. O. Kim, Dong Soo Lee, Joongyub Lee, Kyu‐Chang Wang
SJR Q1Annals of Neurology

OBJECTIVE: Moyamoya disease (MMD) is a cerebrovascular occlusive disease of the bilateral internal carotid arteries that causes a compensatory abnormal vascular network at the base of brain. The rare incidence and various surgical techniques applied have limited the clinical research on MMD. METHODS: We conducted a retrospective analysis of the surgical outcome of 410 pediatric MMD patients. All patients were treated in a relatively uniform scheme at a single institution. The surgical procedures

RheumatologyMedicine
2
Article|65 citations·2018
Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients
Bo Ram Yang, Nam‐Kyong Choi, Mi‐Sook Kim, Jaeyoung Chun, Sang Hyun Joo, Hyesung Kim, Joongyub Lee
SJR Q1PLoS ONEOA

The study confirmed that EIMs are more prevalent among IBD patients than among the general population of Korea. The prevalence of EIMs in IBD patients suggests the need for greater attention and effort in clinical practice.

EpidemiologyMedicine
3
Article|52 citations·2013
A population-based case–control study: proton pump inhibition and risk of hip fracture by use of bisphosphonate
Joongyub Lee, Kyung-Eun Youn, Nam‐Kyong Choi, Jin‐Ho Lee, Dong Yoon Kang, Hong Ji Song, Byung‐Joo Park
SJR Q1Journal of Gastroenterology
GastroenterologyMedicine
4
Article|50 citations·2019
Incremental Peritoneal Dialysis May be Beneficial for Preserving Residual Renal Function Compared to Full-dose Peritoneal Dialysis
Yeonhee Lee, Sung Won Chung, Seokwoo Park, Hyunjin Ryu, Hajeong Lee, Dong Ki Kim, Kwon Wook Joo, Curie Ahn, Joongyub Lee, Kook‐Hwan Oh
SJR Q1Scientific ReportsOA

Maintaining residual renal function (RRF) is a crucial issue in peritoneal dialysis (PD). Incremental dialysis is the practice of initiating PD exchanges less than four times a day in consideration of RRF, and increasing dialysis dose in a step-wise manner as the RRF decreases. We aimed to compare the outcomes of incremental PD and full-dose PD in terms of RRF preservation and other outcomes. This was a single-center, observational study. Data were extracted retrospectively from a cohort of inci

NephrologyMedicine
5
Article|30 citations·2014
Contrast-Induced Nephropathy in Patients Undergoing Intravenous Contrast-Enhanced Computed Tomography in Korea: A Multi-Institutional Study in 101487 Patients
Joongyub Lee, Jeong Yeon Cho, Hak Jong Lee, Yong Yeon Jeong, Chan Kyo Kim, Byung Kwan Park, Deuk Jae Sung, Byung Chul Kang, Sung Il Jung, Eun Ju Lee, Boem-Ha Yi, Seong Jin Park
SJR Q1Korean Journal of RadiologyOA

Risk factors for CIN are prevalent among the patients undergoing CECT. Preventive measures were seemingly underutilized and a system is needed to improve preventive care.

NephrologyMedicine
6
Article|21 citations·2020
High prevalence of systemic hypertension in pediatric patients with moyamoya disease years after surgical treatment
Joongyub Lee, Seung-Ki Kim, Hee Gyung Kang, Il Soo Ha, Kyu‐Chang Wang, Ji Yeoun Lee, Ji Hoon Phi
SJR Q1Journal of Neurosurgery Pediatrics

OBJECTIVE: Although an association between moyamoya disease (MMD) and renovascular hypertension has been acknowledged, the literature on systemic hypertension without renal artery stenosis among patients with MMD is scarce. The authors aimed to evaluate the prevalence and risk factors of hypertension using data from MMD patients who visited an outpatient clinic of a pediatric neurosurgical department in 2016. METHODS: The authors evaluated the blood pressure (BP) of pediatric MMD patients at the

RheumatologyMedicine
7
Article|11 citations·2011
A method to evaluate scientific evidence in clinical preventive medicine
Joongyub Lee, Byung‐Joo Park
SJR Q4Journal of Korean Medical AssociationOA

E valuation of scientific evidence in the medical literature is based on the research methodology, which can be the fundamental tool for medical professionals to improve their practice. Since analytic studies usually provide evidence for generating hypotheses and selecting appropriate research designs, this article aims to review the methods for evaluating the study quality in randomized controlled trials (RCTs), cohort studies, and case-control studies. Critical appraisal of systematic errors i

Statistics, Probability and UncertaintyDecision Sciences
8
Article|11 citations·2018
Prescription of Zolpidem and the Risk of Fatal Motor Vehicle Collisions: A Population-Based, Case-Crossover Study from South Korea
Bo Ram Yang, Ye‐Jee Kim, Mi‐Sook Kim, Sun‐Young Jung, Nam‐Kyong Choi, Byungkwan Hwang, Byung‐Joo Park, Joongyub Lee
SJR Q1CNS Drugs
Cardiology and Cardiovascular MedicineMedicine
9
Article|10 citations·2010
Condom Use and Prevalence of Genital <italic>Chlamydia trachomatis</italic> Among the Korean Female Sex Workers
Joongyub Lee, Sun-Young Jung, Dong Seok Kwon, Minsoo Jung, Byung‐Joo Park
SJR Q2Epidemiology and HealthOA

In Korea, FSWs were not practicing enough self-protection at work with a high prevalence of C. trachomatis. Education for constant practice of protection against sexually transmitted diseases is needed, especially for younger FSWs.

Sociology and Political ScienceSocial Sciences
10
Article|10 citations·2020
Patterns of percutaneous transthoracic needle biopsy (PTNB) of the lung and risk of PTNB-related severe pneumothorax: A nationwide population-based study
Bo Ram Yang, Mi‐Sook Kim, Chang Min Park, Soon Ho Yoon, Kum Ju Chae, Joongyub Lee
SJR Q1PLoS ONEOA

Considering the increasing trend of PTNB, more attention needs to be paid to patients with risk factors for severe pneumothorax.

Pulmonary and Respiratory MedicineMedicine
11
Article|9 citations·2020
Effectiveness of bystander cardiopulmonary resuscitation in improving the survival and neurological recovery of patients with out-of-hospital cardiac arrest: A nationwide patient cohort study
Joongyub Lee, Woojoo Lee, Woojoo Lee, Yu Jin Lee, Hyunman Sim, Won Kyung Lee, Won Kyung Lee
SJR Q1PLoS ONEOA

INTRODUCTION: Few studies have focused on enhancing causality and yielding unbiased estimates on the effectiveness of bystander cardiopulmonary resuscitation (BCPR) on the outcomes of out-of-hospital cardiac arrest (OHCA) in a real-world setting. Therefore, this study evaluated the effect of BCPR on the outcomes of OHCA and its differences according to the characteristics of OHCA. METHODS: This study enrolled all patients with OHCA of cardiac etiology treated by emergency medical services (EMS)

Emergency MedicineMedicine
12
Article|9 citations·2009
The Risk of Fracture with Taking Alpha Blockers for Treating Benign Prostatic Hyperplasia
Joongyub Lee, Nam-Kyoung Choi, Sun-Young Jung, Ye‐Jee Kim, Jong-Mi Seong, Seung‐June Oh, Byung‐Joo Park
SJR Q2Journal of Preventive Medicine and Public HealthOA

Alpha blockers for BPH may increase the risk of fracture in elderly patients who have comorbidities and take the concomitant medications. Alpha blockers need to be prescribed with caution, although some have high prostate specificity.

UrologyMedicine
13
Article|8 citations·2018
The association between antidepressant use and deaths from road traffic accidents: a case-crossover study
Bo Ram Yang, Kyoung-eun Kwon, Ye‐Jee Kim, Nam‐Kyong Choi, Mi‐Sook Kim, Sun‐Young Jung, Ju‐Young Shin, Yong Min Ahn, Byung‐Joo Park, Joongyub Lee
SJR Q1Social Psychiatry and Psychiatric Epidemiology
PharmacologyMedicine
14
Article|4 citations·2022
Impact of treatment adherence on the effectiveness and safety of oral anticoagulants in patients with atrial fibrillation: a retrospective cohort study
Won Kyung Lee, Seong Ill Woo, Dong Keun Hyun, Sun‐Young Jung, Mi‐Sook Kim, Joongyub Lee
SJR Q1European Heart Journal - Quality of Care and Clinical OutcomesOA

AIMS: The impact of adherence to oral anticoagulation has not been reported in terms of absolute risk, which would enhance patients' understanding and treatment adherence. METHODS AND RESULTS: This retrospective cohort study analysed data from the National Health Insurance Database of Korea, from January 2010 to December 2018, on 84 227 patients with non-valvular atrial fibrillation (NVAF). The participants were analysed according to their overall adherence to oral anticoagulants (OACs) and furt

Cardiology and Cardiovascular MedicineMedicine
15
Article|3 citations·2016
Risk of motor vehicle collisions associated with medical conditions and medications: rationale and study protocol
Sun-Young Jung, Byungkwan Hwang, Bo Ram Yang, Ye‐Jee Kim, Joongyub Lee
SJR Q2Injury Prevention

BACKGROUND: Medical conditions and medications may be associated with motor vehicle collisions (MVCs), which pose a major public health problem worldwide. Further epidemiological assessment is necessary for certain diseases and medications. Moreover, since disease aetiology and patterns of medication use may differ among ethnicities and healthcare systems, a population-specific approach is necessary. The present epidemiological study is designed to assess the medical conditions and medications a

Safety, Risk, Reliability and QualityEngineering

Research Areas

NephrologySurgeryCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineEpidemiologyRheumatology

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