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Jun Jeong

Yonsei University · Medicine

About the Lab

Professor Jun Jeong's research lab focuses on translational oncology and patient-centered cancer care, with a strong emphasis on improving outcomes in breast and pancreatic cancers. The lab investigates biomarkers such as tumor-infiltrating lymphocytes (TILs), p16, and p53 proteins to understand tumor biology and predict treatment response. It also explores clinical decision-making in oncology, including the safety of interrupting endocrine therapy for pregnancy and the role of metabolic imaging (e.g., FDG-PET/SUVmax) in predicting recurrence. The research integrates clinical pathology, molecular markers, and health services research to enhance personalized and safe cancer management.

breast cancerpancreatic cancertumor-infiltrating lymphocytesFDG-PEToncology outcomes

Research Overview

Papers
425
Total Citations
8,332
Papers (5y)
142
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
142total
2022
2023
2024
2025
2026
Citations per year (5y)
689total
20222023202420252026

Selected Papers

15
1
Article|83 citations·2006
병원 간호사의 환자안전관리활동 영향요인 연구
정준, 서영준, 남은우

Factors Affecting Patient Safety Management Activities at Nursing Divisions of Two University HospitalsJoon Jeong, Youngjoon Seo‡, Eun Woo NamDept. of Health Administration, Yonsei University

2
Article|64 citations·2020
Comparison of complications according to incision types in nipple-sparing mastectomy and immediate reconstruction
Soeun Park, Chang Ik Yoon, Soong June Bae, Chihwan Cha, Dooreh Kim, Janghee Lee, Sung Gwe Ahn, Tai Suk Roh, Young Seok Kim, Joon Jeong
SJR Q1The BreastOA

Compared with IMF incision, periareolar incision was associated with higher incidences of surgical complications and NAC necrosis. Careful consideration is needed when planning NSM in patients with a large breast volume or a tumor close to the nipple.

SurgeryMedicine
3
Article|54 citations·2021
Who are the women who enrolled in the POSITIVE trial: A global study to support young hormone receptor positive breast cancer survivors desiring pregnancy
Ann H. Partridge, Samuel M. Niman, Monica Ruggeri, Fedro A. Peccatori, Hatem A. Azim, Marco Colleoni, Cristina Saura, Chikako Shimizu, Anna Barbro Sætersdal, Judith R. Kroep, Audrey Mailliez, Ellen Warner
SJR Q1The BreastOA

The characteristics of participants in the POSITIVE study provide insights to which patients and doctors considered it acceptable to interrupt ET to pursue pregnancy. Similarities and variations from a regional, sociodemographic, disease and treatment standpoint suggest specific sociocultural attitudes across the world.

OncologyMedicine
4
Article|48 citations·2018
Comparison of tumor-infiltrating lymphocytes of breast cancer in core needle biopsies and resected specimens: a retrospective analysis
Yoon Jin, Sung Gwe Ahn, Soong June Bae, Chang Ik Yoon, Ja Yeong Seo, Woo Hee Jung, Eun Ju Son, Joon Jeong
SJR Q1Breast Cancer Research and TreatmentOA
OncologyMedicine
5
Article|44 citations·2005
Clinical Significance of p16 Protein Expression Loss and Aberrant p53 Protein Expression in Pancreatic Cancer
Joon Jeong, Young Nyun Park, Joon Seong Park, Dong Sup Yoon, Hoon Sang Chi, Byong Ro Kim
SJR Q2Yonsei Medical JournalOA

Pancreatic cancer is a disease with poor prognosis mainly due to low resection rates and late diagnosis. To increase resectability and improve survival rates, a better understanding of pancreatic cancer pathogenesis and more effective screening techniques are required. New methods, such as genetic and molecular alterations, may suggest novel approaches for pancreatic cancer diagnosis and treatment. We immunohistochemically investigated 44 formalin-fixed, paraffin-embedded specimens of pancreatic

OncologyMedicine
6
Article|37 citations·2018
Comparisons of tumor-infiltrating lymphocyte levels and the 21-gene recurrence score in ER-positive/HER2-negative breast cancer
Sung Gwe Ahn, Yoon Jin, Soong June Bae, Chanik Yoon, Hak Woo Lee, Joon Jeong
SJR Q2BMC CancerOA

BACKGROUND: Recent studies have shown that tumors with extensive tumor-infiltrating lymphocytes (TILs) have a higher probability of pathologic complete response, even in luminal/human epidermal growth factor 2 (HER2)-negative breast cancer. We compared TIL levels and the 21-gene recurrence score (RS) in estrogen receptor (ER)-positive/HER2-negative breast cancer. METHODS: We evaluated the percentage of stromal TILs in 198 ER-positive/HER2-negative patients in whom RS was obtained by examining sl

OncologyMedicine
7
Article|37 citations·2014
Standardized uptake value of 18F-fluorodeoxyglucose positron emission tomography for prediction of tumor recurrence in breast cancer beyond tumor burden
Sung Gwe Ahn, Jong Tae Park, Hak Min Lee, Hak Woo Lee, Tae Joo Jeon, Kyunghwa Han, Seung Ah Lee, Seung Myung Dong, Young Hoon Ryu, Eun Ju Son, Joon Jeong
SJR Q1Breast Cancer ResearchOA

INTRODUCTION: 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) can reveal the metabolic activity of malignant tumors. Recent advances gained from molecular studies suggest that tumor biology can be a good predictor of prognosis in breast cancer. We compared the ability of maximum standardized uptake values (SUVmax) derived by FDG-PET with tumor burden in predicting tumor recurrence for patients with breast cancer. METHODS: 496 patients with breast cancer who underwent preoperative F

Radiology, Nuclear Medicine and ImagingMedicine
8
Article|36 citations·2020
Prognostic value of neutrophil-to-lymphocyte ratio in human epidermal growth factor receptor 2-negative breast cancer patients who received neoadjuvant chemotherapy
Soong June Bae, Yoon Jin, Chang Ik Yoon, Dooreh Kim, Janghee Lee, Soeun Park, Chihwan Cha, Jee Ye Kim, Sung Gwe Ahn, Hyung Seok Park, Seho Park, Seung Il Kim
SJR Q1Scientific ReportsOA

We aimed to investigate the correlation between neutrophil-to-lymphocyte ratio (NLR) and pathologic complete response (pCR) and survival outcomes in human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients who received neoadjuvant chemotherapy. The baseline NLR was evaluated in non-metastatic, HER2-negative breast cancer patients who received neoadjuvant chemotherapy. Baseline NLR was calculated as absolute neutrophil per lymphocyte count from pre-treatment blood samples.

OncologyMedicine
9
Article|33 citations·2000
Rupture of the rectosigmoid colon with evisceration of the small bowel through the anus
Joon Jeong, Joon Seong Park, Chang Gyoo Byun, Dong Sup Yoon, Seung Kook Sohn, Yoon Ho Lee, Hoon Sang
SJR Q2Yonsei Medical JournalOA

Spontaneous rupture of the rectosigmoid colon and herniation of the small intestine through the rupture site and eventual evisceration through the anus is a very rare event. In the literature, only 42 cases have been reported. The majority of them occurred in patients with rectal prolapse and one case was reported in association with a third-degree uterine prolapse. We experienced an 81-year-old female patient with rectal prolapse and second-degree uterine prolapse complicated by spontaneous per

RheumatologyMedicine
10
Article|29 citations·2005
Clinical Significance of p16 Protein Expression Loss and Aberrant p53 Protein Expression in Pancreatic Cancer
정준, 박영년, 박준성, 윤동섭, 지훈상, 김병로
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120050460040519

Pancreatic cancer is a disease with poor prognosis mainly due to low resection rates and late diagnosis. To increase resectability and improve survival rates, a better understanding of pancreatic cancer pathogenesis and more effective screening techniques are required. New methods, such as genetic and molecular alterations, may suggest novel approaches for pancreatic cancer diagnosis and treatment. We immunohistochemically investigated 44 formalin-fixed, paraffin-embedded specimens of pancreatic

11
Article|28 citations·2020
Genomic Signature of the Standardized Uptake Value in 18F-Fluorodeoxyglucose Positron Emission Tomography in Breast Cancer
Seon‐Kyu Kim, Sung Gwe Ahn, Jeong-Yeon Mun, Mi-So Jeong, Soong June Bae, Ju‐Seog Lee, Joon Jeong, Sun-Hee Leem, In‐Sun Chu
SJR Q1CancersOA

The standardized uptake value (SUV), an indicator of the degree of glucose uptake in 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), has been used for predicting the clinical behavior of malignant tumors. However, its characteristics have been insufficiently explored at the genomics level. Here, we aim to identify genomic signatures reflecting prognostic SUV characteristics in breast cancer (BRC). Through integrative genomic profiling of 3710 BRC patients, including 254 patients w

Radiology, Nuclear Medicine and ImagingMedicine
12
Article|26 citations·2020
Radiotherapy-Induced High Neutrophil-to-Lymphocyte Ratio is a Negative Prognostic Factor in Patients with Breast Cancer
Chang Ik Yoon, Dooreh Kim, Sung Gwe Ahn, Soong June Bae, Chihwan Cha, Soeun Park, Seho Park, Seung Il Kim, Hye Sun Lee, Juyoung Park, Joon Jeong
SJR Q1CancersOA

Radiotherapy (RT) is the standard of care following breast-conserving operation in breast cancer patients. The neutrophil-to-lymphocyte ratio (NLR) reflects the systemic change caused as a result of the radiotherapy. We aimed to evaluate the association between RT and the change in NLR following the receipt of RT, and to investigate the prognostic impact. We retrospectively reviewed NLR values of breast cancer patients taken before the administration of the first and the last session of RT. The

OncologyMedicine
13
Article|25 citations·2013
The Difference in Prognostic Factors between Early Recurrence and Late Recurrence in Estrogen Receptor-Positive Breast Cancer: Nodal Stage Differently Impacts Early and Late Recurrence
Sung Gwe Ahn, Hak Min Lee, Sang-Hoon Cho, Suk Jin Bae, Seung Ah Lee, Seung Hyun Hwang, Joon Jeong, Hy-De Lee
SJR Q1PLoS ONEOA

Nodal burden had an attenuated influence on late recurrence, which suggests that, unlike early recurrence, tumor biology might have a more important role than tumor load for late recurrence in ER-positive disease.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
14
Article|24 citations·2019
High A20 expression negatively impacts survival in patients with breast cancer
Chang Ik Yoon, Sung Gwe Ahn, Soong June Bae, Yun Shin, Chihwan Cha, Soeun Park, Ji-Hyung Lee, Akira Ooshima, Hye Sun Lee, Kyung-Min Yang, Seong Jin Kim, Seok Hee Park
SJR Q1PLoS ONEOA

We found that A20 expression is a poor prognostic marker in breast cancer. The prognostic impact of A20 was pronounced in aggressive tumors, such as HER2-positive and TNBC subtypes. Our findings suggested that A20 may be a valuable target in patients with aggressive breast cancer.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
Article|24 citations·2021
Body mass index and absolute lymphocyte count predict disease-free survival in Korean breast cancer patients
Sung Min Ko, Janghee Lee, Soong June Bae, Su Jung Baik, Junghwan Ji, Dooreh Kim, Sung Gwe Ahn, Joon Jeong
SJR Q1British Journal of CancerOA

BACKGROUND: Our study evaluated the association between body mass index (BMI) and absolute lymphocyte count (ALC) in breast cancer patients and healthy females. Additionally, we determined the prognostic value of these factors in breast cancer. METHODS: We retrospectively identified 1225 primary invasive breast cancer patients and 35,991 healthy females. Factors including BMI and complete blood count associated with disease-free survival (DFS) were assessed using a multi-variable Cox proportiona

OncologyMedicine

Research Areas

OncologyCancer ResearchPulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingMolecular BiologySurgery

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