Jung Jun Lee
Yonsei University · Medicine
About the Lab
Professor Jung Jun Lee's research lab specializes in clinical and translational research in solid organ transplantation, with a focus on improving outcomes in liver and kidney transplant recipients. The lab investigates immunosuppressive strategies, rejection management—particularly steroid-resistant acute rejection—and the impact of metabolic and immunological risk factors on graft and patient survival. Key research directions include the use of biologics like rabbit anti-thymocyte globulin, the role of donor-specific antibodies and panel reactive antibodies in transplant outcomes, and long-term complications such as post-transplant malignancies. The lab also explores interventional approaches to vascular access in dialysis patients, emphasizing endovascular management of immature arteriovenous fistulas.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Acute cellular rejection after liver transplantation (LT) can be treated with steroid pulse therapy, but there is no ideal treatment for steroid-resistant acute rejection (SRAR). We aimed to determine the feasibility and potential complications of rabbit anti-thymocyte globulin (rATG) application to treat SRAR in liver transplant recipients. We retrospectively reviewed medical records of 429 recipients who underwent LT at Severance Hospital between January 2010 and March 2015. We compared clinic
BACKGROUND: Metabolic syndrome (MetS) is prevalent in patients with end-stage kidney disease, and kidney transplantation is expected to modify the metabolic status. However, whether changes in metabolic status at the time of transplantation affect recipient outcomes remains unclear. METHODS: We analyzed 4187 recipients registered in a nationwide prospective cohort from 2014 to 2020. MetS was defined as the presence of three or more components of the metabolic syndrome. Patients were classified b
Advances in patient care and immunosuppressive drugs have improved graft survival, resulting in an increase in kidney transplantation (KT); however, persistent immunosuppression is thought to cause late occurrence of cancer. This population-based study consisted of a total of 14,842 patients whose data from the years 2002 to 2017 were collected from the National Health Information Database in South Korea. Malignancies occurred in 7.6% of the total KT patients. Prostate and thyroid cancers were t
In LDLT, the presence of multiple DSAs and high PRA seemed to be associated with poor graft outcomes, although our results did not reach statistical significance. Large cohort studies are necessary to clarify the impact of DSA and PRA in LDLT.
The optimal immunosuppressive strategy for renal transplant recipients at high immunologic risk remains a topic of investigation. This prospective single arm pilot study was undertaken to evaluate the safety and efficacy of a combined tacrolimus and sirolimus regimen in recipients at immunological high risk and to compare outcomes with a contemporaneous control group received tacrolimus and mycophenolate mofetil. Patients that received a renal allograft between 2010 and 2011 at high risk (define
To evaluate the outcomes and prognostic factors of endovascular management in immature arteriovenous fistula (AVF) for hemodialysis.From April 2007 to September 2017, 54 patients (male:female = 31:23, mean age 65.63 years, range 33-90 years) who underwent endovascular management for the salvage of immature AVF were retrospectively reviewed. Clinical data, procedural details, and results were evaluated. Primary and secondary patency rates and factors influencing the patency were also analyzed.Tec
To reduce hepatitis B virus reinfection after liver transplantation (LT), patients often receive antihepatitis B immunoglobulin (HBIG) alone or combined with antiviral nucleoside/nucleotide analogs (NUCs); however, proximal renal tubular dysfunction (RTD) that was induced by NUCs in liver recipients was rarely reported. Here, we analyzed RTD and renal impairment (RI) following adefovir (ADV) and lamivudine (LAM) treatment in liver recipients. We retrospectively reviewed medical records of patien
The aim of this study is to investigate whether or not delayed graft function (DGF) and pre-transplant sensitization have synergistic adverse effects on allograft outcome after deceased donor kidney transplantation (DDKT) using the Korean Organ Transplantation Registry (KOTRY) database, the nationwide prospective cohort. The study included 1359 cases between May 2014 and June 2019. The cases were divided into 4 subgroups according to pre-sensitization and the development of DGF post-transplant [
Han Hee Lee, M.D., Jung Jun Lee, M.D., Man Ki Ju, M.D., Myoung Soo Kim, M.D., Kyu Ha Huh, M.D., Eyi Sang Yoon, M.D., Dong Jin Joo, M.D., Soo Jin Kim, M.D., Soon Il Kim, M.D. and Yu Seun Kim, M.D.. J Korean Soc Transplant 2009;23:233-6. https://doi.org/10.4285/jkstn.2009.23.3.233
본 논문에서는 모니터 위에 설치된 카메라를 통해 입력된 사용자의 2차원 얼굴 영상을 이용하여, 사용자가 모니터 상에 쳐다보고 있는 응시 위치를 파악하는 방법을 제안한다. 본 논문에서는 사용자의 눈동자 움직임은 고려하지 않고 얼굴의 회전 및 이동만을 고려하였다. 제안하는 방법은 얼굴의 회전에 의한 응시위치와 얼굴의 좌우상하 이동량을 각각 계산하여 이 둘을 결합함으로써 모니터상의 응시위치를 추정하는 것이다. 얼굴 특징점의 기하학적 형태변화를 입력으로 하는 신경망(다층 퍼셉트론)을 이용하여 얼굴의 회전에 의한 응시위치를 구하였으며 영상처리 알고리즘을 이용하여 입력영상으로부터 실시간으로 얼굴의 이동량을 추정하였다. 실험결과 19인치 모니터를 사용하고 사용자가 모니터와의 거리를 50∼70cm 정도 유지하며 얼굴의 이동 및 회전을 통하여 모니터를 바라볼 때 약 2.11인치의 응시 위치 추정 오차를 보이는 것으로 나타났다. 처리시간은 Pentium PC(233MHz)환경에서 320×240 화소
Yun Tae Jung, M.D., Jung Jun Lee, M.D., Su Hyung Lee, M.D., A-Lan Lee, M.D., Kyu Ha Huh, M.D., Myoung Soo Kim, M.D., Soon Il Kim, M.D., Yu Seun Kim, M.D. and Dong Jin Joo, M.D.. J Korean Soc Transplant 2013;27:121-7. https://doi.org/10.4285/jkstn.2013.27.3.121
Research Areas
Dive deeper into Jung Jun Lee's research on Nubint
Open this lab's papers in the app to read with AI, summarize, and cite in your writing.