Kang Min Kim
Seoul National University · Medicine
About the Lab
Professor Kang Min Kim's research lab specializes in clinical and translational neuroscience, focusing on cerebrovascular diseases such as moyamoya disease and intracranial atherosclerotic stenosis. The lab investigates the natural history, risk factors, and treatment outcomes of intracranial hemorrhage, with an emphasis on radiosurgical interventions and hemodynamic evaluation. Additionally, the lab explores the pharmacokinetics and biological properties of natural compounds, including decursin and probiotic strains like *Bacillus polyfermenticus*, for potential therapeutic applications. The integration of medical imaging, molecular biology, and computational modeling underpins the lab’s multidisciplinary approach to improving neurological outcomes and developing novel treatments.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15BACKGROUND: Recurrent hemorrhage is a serious neurosurgical problem in adult moyamoya disease (MMD) patients. OBJECTIVE: To find the natural history and risk factors of recurrent hemorrhage in cases of adult hemorrhagic MMD. METHODS: One hundred seventy-six adult MMD patients presenting with hemorrhage were enrolled. Patients' medical records and radiological images were retrospectively reviewed. Clinical and radiological features of recurrent hemorrhage, and related risk factors were analyzed.
OBJECTIVE: Gamma Knife Stereotactic Radiosurgery (GK SRS) has become an important treatment modality for vestibular schwannomas. We evaluated the tumor control rate, patterns of tumor volume change and preservation of hearing following low-dose radiation for vestibular schwannomas in a homogeneous cohort group in which the mean marginal dose was 12 Gy. METHODS: A total of 59 patients were enrolled in this study. All enrolled patients were followed-up for at least 5 years and the radiation dose w
The pharmacokinetics of decursin and decursinol angelate (D/DA) was investigated in male SD rats following oral and intravenous administration. D/DA and metabolites obtained from in vitro samples were evaluated by LC/MS. The level of D/DA and metabolized decursinol in the blood following oral and intravenous administration declined according to first-order kinetics, with T1/2 values of 56.67, 58.01 and 57.22 h, respectively, being observed after administration of a dose of 2 mg/kg body weight. T
INTRODUCTION: The effectiveness of a scoring system based on the circle of Willis for evaluations of collateral circulation was studied in patients with intracranial atherosclerotic stenosis. METHODS: Eighty-three patients who underwent medical or endovascular treatment for symptomatic and severe intracranial atherosclerotic stenosis were enrolled in the study. Clinical profiles, status of the circle of Willis (poor and good integrity group), and clinical outcomes were analyzed. Primary endpoint
The identification and characterization of Bacillus polyfermenticus KJS-2 (B. polyfermenticus KJS-2) was conducted using TEM, an API 50CHB kit, 16S rDNA sequencing, a phylogenetic tree, and catalase and oxidase testing. The conversion rate of glucose to lactic acid by B. polyfermenticus KJS-2 was found to be 60.71+/-4.9%. In addition, treatment of B. polyfermenticus KJS-2 with artificial gastric juice (pH 2.0) and bile acid (pH 6.5) for 4 h resulted in a final viability of 140+/-7.9% and 108+/-3
A shift from coal to liquefied natural gas for electricity generation can mitigate CO<sub>2</sub> emissions and respond to the intermittent and variable characteristics of renewable energy. With this objective, numerical simulation was performed in this study to determine the optimal position of the methane injector and evaluate the achievable reduction in NO <i><sub>x</sub></i> emissions before applying methane cofiring to an existing 550 MW tangentially fired pulverized-coal boiler (Boryeong U
The need to reduce global carbon dioxide (CO2) emissions is driving the conversion of coal-fired power plants to use methane, which can reduce CO2 emissions by >40%. However, conducting gas firing in coal boilers changes the heat transfer profile; therefore, preliminary evaluations using computational fluid dynamics are required prior to conversion. Here, methane was used as a heat input source in the simulation of an existing coal boiler, and combustion, nitrogen oxides (NOx) emission charac
BACKGROUND: Reconstructive strategies for unruptured vertebral artery dissecting aneurysms (VADAs) have increasingly relied on newly developed endovascular devices. However, their clinical performance metrics are seldom reported. OBJECTIVE: To compare stent-assisted coil embolization (SACE) and flow-diverting stent (FDS) deployment as treatments for unruptured VADAs, focusing on efficacy and safety. METHODS: A total of 72 VADAs were submitted to SACE (n = 48) or FDS (n = 24) between April 2009 a
In this work, subair injection was proposed to improve the combustibility and NOx emission in a 500 MW tangentially fired coal boiler. The location of injection ports was determined based on the coal particle trajectory and its effect was investigated numerically. The flow rate of subair was set to 0, 5, and 10% of the total combustion air. The secondary air flow rate was decreased appropriately to ensure that the total quantity of combustion air remained constant. The over-fire air was not adju
In this paper, a new synthesis of carbon nanofibers (CNFs)/carbon nanowalls (CNWs) was performed to improve the characteristics of anode materials of lithium-ion batteries by using the advantages offered by CNWs and CNFs. Among the carbon-based nanomaterials, CNWs provide low resistance and high specific surface area. CNFs have the advantage of being stretchable and durable. The CNWs were grown using a microwave plasma-enhanced chemical vapor deposition (PECVD) system with a mixture of methane (
Research Areas
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