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Ko Changnam

Kyung Hee University · Medicine

About the Lab

Professor Ko Changnam's research lab specializes in integrative and complementary medicine, with a primary focus on acupuncture and related therapies for neurological and motor disorders. The lab investigates the efficacy, safety, and physiological mechanisms of acupuncture, electroacupuncture, and moxibustion in conditions such as Parkinson’s disease, stroke-induced spasticity, and other movement disorders. Key research directions include evaluating neurovascular responses (e.g., cerebral blood flow changes) and identifying clinical biomarkers like de qi sensations and short-term treatment reactions.

acupunctureParkinson's diseasestroke spasticitycerebral blood flowcomplementary therapy

Research Overview

Papers
274
Total Citations
2,042
Papers (5y)
73
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
73total
2021
2022
2023
2024
2025
Citations per year (5y)
243total
20212022202320242025

Selected Papers

15
1
Article|166 citations·2012
Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease
Seung‐Yeon Cho, So-Ra Shim, Hak Young Rhee, Hi‐Joon Park, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Ki‐Ho Cho, Seong-Uk Park
SJR Q1Parkinsonism & Related Disorders
PharmacologyMedicine
2
Article|72 citations·2014
Tetramethylpyrazine, a natural alkaloid, attenuates pro-inflammatory mediators induced by amyloid β and interferon-γ in rat brain microglia
Mia Kim, Sung-Ok Kim, Moonsung Lee, Joon‐Hyung Lee, Woo‐Sang Jung, Sang‐Kwan Moon, Young-Suk Kim, Ki‐Ho Cho, Chang‐Nam Ko, Eunjoo H. Lee
SJR Q1European Journal of Pharmacology
NeurologyNeuroscience
3
Review|70 citations·2020
Exercise Therapies for Parkinson’s Disease: A Systematic Review and Meta-Analysis
Hyun-Young Choi, Ki‐Ho Cho, Chul Jin, Ji‐Eun Lee, Tae‐Hun Kim, Woo‐Sang Jung, Sang‐Kwan Moon, Chang‐Nam Ko, Seung‐Yeon Cho, Chan‐Yong Jeon, Tae‐Young Choi, Myeong Soo Lee
SJR Q2Parkinson s DiseaseOA

Recently, rehabilitative exercise therapies have been described as an important method of overcoming the limitations of the conventional therapies for Parkinson's disease. The present study aimed to evaluate efficacy and safety of exercise therapies for Parkinson's disease. Randomized controlled trials that evaluated exercise therapies in patients with Parkinson's disease until December 2016 were searched for in five electronic databases: PubMed, CENTRAL, EMBASE, OASIS, and CNKI. Eighteen studie

NeurologyMedicine
4
Article|63 citations·2002
Fecal metabolic activities of herbal components to bioactive compounds
Dai-Sik Lee, Youngsuk Kim, Chang‐Nam Ko, Ki‐Ho Cho, Hyung-Sup Bae, Kyung-Sup Lee, Jung-Jin Kim, Eunkyung Park, Dong‐Hyun Kim
SJR Q1Archives of Pharmacal Research
PharmacologyPharmacology, Toxicology and Pharmaceutics
5
Article|61 citations·2017
Efficacy of Combined Treatment with Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment for Parkinson's Disease
Seung‐Yeon Cho, Youngeun Lee, Kyeong-Hee Doo, Ji‐Hyun Lee, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Ho Kim, Hak Young Rhee, Hi‐Joon Park, Seong-Uk Park
The Journal of Alternative and Complementary Medicine

It is suggested that the combined treatment of acupuncture and BVA might be safe and useful adjunctive treatment for patients with IPD.

PharmacologyMedicine
6
Article|57 citations·2015
A Prospective Open-Label Study of Combined Treatment for Idiopathic Parkinson's Disease Using Acupuncture and Bee Venom Acupuncture as an Adjunctive Treatment
Kyeong-Hee Doo, Jihyun Lee, Seung‐Yeon Cho, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Ho Kim, Hi‐Joon Park, Seong-Uk Park
The Journal of Alternative and Complementary Medicine

Combined treatment with acupuncture and BVA showed promising results as a safe adjunctive therapy for PD.

PharmacologyMedicine
7
Article|56 citations·2015
Can the Neutrophil-to-Lymphocyte Ratio Appropriately Predict Carotid Artery Stenosis in Patients with Ischemic Stroke?—A Retrospective Study
Sangho Hyun, Seungwon Kwon, Seung‐Yeon Cho, Seong-Uk Park, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, KiHo Cho
SJR Q1Journal of Stroke and Cerebrovascular Diseases
Pulmonary and Respiratory MedicineMedicine
8
Review|52 citations·2017
Effectiveness and safety of acupuncture in the treatment of Parkinson’s disease: A systematic review and meta-analysis of randomized controlled trials
Hyeon-seok Noh, Seungwon Kwon, Seung‐Yeon Cho, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Seong-Uk Park
SJR Q1Complementary Therapies in Medicine
Complementary and alternative medicineMedicine
9
Article|45 citations·2003
Antispastic Effect of Electroacupuncture and Moxibustion in Stroke Patients
Sang‐Kwan Moon, Yeon-Kyu Whang, Seong-Uk Park, Chang‐Nam Ko, Youngsuk Kim, Hyung-Sup Bae, Ki‐Ho Cho
SJR Q1The American Journal of Chinese Medicine

Spasticity is a frequently observed motor impairment that develops after stroke. The objective of this study was to evaluate the efficacy of electroacupuncture (EA) and moxibustion (Mox) on spasticity due to stroke. The subjects consisted of 35 stroke patients with elbow spasticity whose mean duration of stroke was 2.97 months. Fifteen patients were randomized to the EA group, ten to Mox, and ten to control. Every other day, 30 minutes of electrical stimulation with a frequency of 50 Hz was give

NeurologyMedicine
10
Article|44 citations·2013
Bee venom acupuncture point injection for central post stroke pain: A preliminary single-blind randomized controlled trial
Seung‐Yeon Cho, Jooyoung Park, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Seong-Uk Park
SJR Q1Complementary Therapies in Medicine
PharmacologyMedicine
11
Article|42 citations·2009
Short-Term Reactions to Acupuncture Treatment and Adverse Events Following Acupuncture: A Cross-Sectional Survey of Patient Reports in Korea
Seong-Uk Park, Chang‐Nam Ko, Hyung-sup Bae, Woo‐Sang Jung, Sang‐Kwan Moon, Ki‐Ho Cho, Youngsuk Kim, Jung-Mi Park
The Journal of Alternative and Complementary Medicine

Short-term acupuncture reactions and de qi were related to the age group. With the exception of bleeding, there were no adverse events related to the acupuncture treatment in this study. We consider acupuncture treatment to be very safe if the practitioners are well educated, trained and experienced. The number of post-treatment positive short-term acupuncture reactions was 12 times higher than that of the negative short-term reactions. Overall, subjects were comparatively satisfied with the acu

Complementary and alternative medicineMedicine
12
Article|38 citations·2013
A comparison of brain activity between healthy subjects and stroke patients on fMRI by acupuncture stimulation
Seung‐Yeon Cho, Mia Kim, Jong-joo Sun, Geon‐Ho Jahng, Hengjun J. Kim, Seong-Uk Park, Woo‐Sang Jung, Chang‐Nam Ko, Jung‐Mi Park
SJR Q2Chinese Journal of Integrative Medicine
Complementary and alternative medicineMedicine
13
Article|37 citations·2011
Effects of GV20 Acupuncture on Cerebral Blood Flow Velocity of Middle Cerebral Artery and Anterior Cerebral Artery Territories, and CO 2 Reactivity During Hypocapnia in Normal Subjects
Hyung-sik Byeon, Sang‐Kwan Moon, Seong-Uk Park, Woo‐Sang Jung, Jung‐Mi Park, Chang‐Nam Ko, Ki‐Ho Cho, Young‐Suk Kim, Hyung-sup Bae
The Journal of Alternative and Complementary Medicine

The data suggest that GV20 acupuncture treatment increases cerebral blood flow. The results of this small-scale study provide preliminary evidence for acupuncture effectiveness.

Complementary and alternative medicineMedicine
14
Review|31 citations·2018
Adjunctive herbal medicine treatment for patients with acute ischemic stroke: A systematic review and meta-analysis
Chang-ho Han, Mikyung Kim, Seung‐Yeon Cho, Woo‐Sang Jung, Sang‐Kwan Moon, Jung‐Mi Park, Chang‐Nam Ko, Ki‐Ho Cho, Seungwon Kwon
SJR Q1Complementary Therapies in Clinical Practice
EpidemiologyMedicine
15
letter|28 citations·2020
The end of ‘cordon sanitaire’ in Wuhan: the role of non-pharmaceutical interventions against COVID-19
Kelvin H. Wan, Susan S. Huang, Chang‐Nam Ko, Dennis S.C. Lam
SJR Q1Public HealthOA
Modeling and SimulationMathematics

Research Areas

PharmacologyNeurologyComplementary and alternative medicinePhysiologyAerospace EngineeringEpidemiology

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