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Koung Mi Kang

Seoul National University · Medicine

About the Lab

Professor Koung Mi Kang's research lab specializes in clinical and quantitative MRI applications, focusing on advanced diffusion and perfusion imaging techniques to improve the diagnosis and characterization of neurological and abdominal tumors. The lab investigates the role of IVIM, DWI, ASL, and contrast-enhanced MRI in differentiating tumor types, assessing malignancy, and understanding cerebrovascular and neurodegenerative pathologies. Their work also explores the impact of MRI contrast agents on tissue relaxation times and the association between cerebrovascular disease and neurodegenerative disorders such as Alzheimer’s disease.

diffusion MRIperfusion imagingbrain tumorneurodegenerationMR contrast agents

Research Overview

Papers
183
Total Citations
2,710
Papers (5y)
78
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
78total
2022
2023
2024
2025
2026
Citations per year (5y)
365total
20222023202420252026

Selected Papers

15
1
Article|161 citations·2013
Intravoxel Incoherent Motion Diffusion-weighted MR Imaging for Characterization of Focal Pancreatic Lesions
Koung Mi Kang, Jeong Min Lee, Jeong Hee Yoon, Berthold Kiefer, Joon Koo Han, Byung Ihn Choi
SJR Q1Radiology

IVIM-derived perfusion-related parameters could be helpful for the differentiation of common malignant tumors in the pancreas and for distinguishing malignant from benign IPMNs. D(fast) and f were more valuable parameters in the differentiation of PACs from NETs than were ADC and D(slow).

Radiology, Nuclear Medicine and ImagingMedicine
2
Article|63 citations·2013
Added value of diffusion‐weighted imaging to MR cholangiopancreatography with unenhanced mr imaging for predicting malignancy or invasiveness of intraductal papillary mucinous neoplasm of the pancreas
Koung Mi Kang, Jeong Min Lee, Cheong‐Il Shin, Jee Hyun Baek, Seung Ho Kim, Jeong Hee Yoon, Joon Koo Han, Byung Ihn Choi
SJR Q1Journal of Magnetic Resonance Imaging

PURPOSE: To investigate the added value of diffusion-weighted imaging (DWI) to magnetic resonance cholangiopancreatography (MRCP) with unenhanced MR imaging for predicting the malignancy or invasiveness of intraductal papillary mucinous neoplasms (IPMNs). MATERIALS AND METHODS: Following Institutional Review Board (IRB) approval, this retrospective study included 52 patients with surgically resected IPMNs and who underwent MRCP, unenhanced MRI, and DWI. Three blinded radiologists evaluated the t

Pulmonary and Respiratory MedicineMedicine
3
Article|37 citations·2017
T1 Shortening in the Globus Pallidus after Multiple Administrations of Gadobutrol: Assessment with a Multidynamic Multiecho Sequence
Koung Mi Kang, Seung Hong Choi, Moonjung Hwang, Tae Jin Yun, Ji‐hoon Kim, Chul‐Ho Sohn
SJR Q1Radiology

Purpose To determine the association between the administration of the macrocyclic contrast medium gadobutrol and T1 relaxation time in the brains of patients with normal renal function by using multidynamic multiecho (MDME) magnetic resonance (MR) imaging sequences. Materials and Methods The institutional review board approved this retrospective study, and the need to obtain written informed consent was waived. This study included 46 patients (revealed by an electronic medical record search) wh

Materials ChemistryMaterials Science
4
Article|29 citations·2017
Detection of crossed cerebellar diaschisis in hyperacute ischemic stroke using arterial spin-labeled MR imaging
Koung Mi Kang, Chul‐Ho Sohn, Seung Hong Choi, Keun‐Hwa Jung, Roh‐Eul Yoo, Tae Jin Yun, Ji‐hoon Kim, Sun‐Won Park
SJR Q1PLoS ONEOA

ASL imaging could detect CCD in 75% of patients with hyperacute infarction. We found that CCD was more prevalent in patients with arterial occlusion, larger ischemic brain volumes, and higher initial NIHSS and mRS scores. In particular, vessel occlusion and initial mRS score appeared to be significantly related with CCD pathophysiology in the hyperacute stage.

EpidemiologyMedicine
5
Article|29 citations·2020
Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers
Koung Mi Kang, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Hye Jeong Choi, Eunjung Lee, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Chul‐Ho Sohn, Dong Young Lee
SJR Q1Alzheimer s Research & TherapyOA

BACKGROUND: To clarify whether atherosclerosis of the carotid and intracranial arteries is related to Alzheimer's disease (AD) pathology in vivo, we investigated the associations of carotid and intracranial artery stenosis with cerebral beta-amyloid (Aβ) deposition and neurodegeneration in middle- and old-aged individuals. Given different variations of the pathologies between cognitive groups, we focused separately on cognitively normal (CN) and cognitively impaired (CI) groups. METHODS: C] Pitt

Psychiatry and Mental healthMedicine
6
Article|27 citations·2024
MRI Scoring Systems for Predicting Isocitrate Dehydrogenase Mutation and Chromosome 1p/19q Codeletion in Adult-type Diffuse Glioma Lacking Contrast Enhancement
Koung Mi Kang, Jiyoung Song, Yunhee Choi, Chanrim Park, Ji Eun Park, Ho Sung Kim, Sung‐Hye Park, Chul‐Kee Park, Seung Hong Choi
SJR Q1Radiology

Simple scoring systems using standard clinical MRI were developed and validated for predicting isocitrate dehydrogenase and 1p/19q codeletion status in adult-type diffuse gliomas lacking contrast enhancement.

GeneticsMedicine
7
Article|26 citations·2015
Correlation of Asymmetry Indices Measured by Arterial Spin-Labeling MR Imaging and SPECT in Patients with Crossed Cerebellar Diaschisis
Koung Mi Kang, Chul‐Ho Sohn, B.S. Kim, Y.I. Kim, Seung Hong Choi, Taeho Yun, Ji‐hoon Kim, Sang‐Won Park, Gi Jeong Cheon, Moon Hee Han
SJR Q1American Journal of NeuroradiologyOA

BACKGROUND AND PURPOSE: Crossed cerebellar diaschisis, not only a secondary result of supratentorial infarction but also an indicator of clinical outcomes, has frequently been reported on PET and SPECT but has been rarely described with arterial spin-labeling MR imaging. The purpose of this study was to determine the ability of arterial spin-labeling MR imaging to evaluate crossed cerebellar diaschisis compared with that of SPECT. To our knowledge, this is the first study to validate arterial sp

Pediatrics, Perinatology and Child HealthMedicine
8
Article|25 citations·2017
Evaluation of Gadolinium Retention After Serial Administrations of a Macrocyclic Gadolinium-Based Contrast Agent (Gadobutrol)
Roh‐Eul Yoo, Chul‐Ho Sohn, Koung Mi Kang, Tae Jin Yun, Seung Hong Choi, Ji-hoon Kim, Sun‐Won Park
SJR Q1Investigative Radiology

OBJECTIVE: There has been controversy as to whether gadobutrol, one of the widely used macrocyclic gadolinium-based contrast agents, can lead to gadolinium retention after serial injections. Our aim was to validate whether serial administrations of gadobutrol can cause signal increase in the dentate nucleus (DN) and globus pallidus (GP) on unenhanced T1-weighted magnetic resonance (MR) images due to gadolinium retention. MATERIALS AND METHODS: A total of 189 patients who had undergone at least 2

Materials ChemistryMaterials Science
9
Article|24 citations·2018
Application of Synthetic MRI for Direct Measurement of Magnetic Resonance Relaxation Time and Tumor Volume at Multiple Time Points after Contrast Administration: Preliminary Results in Patients with Brain Metastasis
Koung Mi Kang, Seung Hong Choi, Moonjung Hwang, Roh‐Eul Yoo, Tae Jin Yun, Ji‐hoon Kim, Chul‐Ho Sohn
SJR Q1Korean Journal of RadiologyOA

Magnetic resonance relaxation times and the volumes of the whole tumor and the inner enhancing portion were measured larger on the 10 minutes or 20 minutes delayed images than on the 1 minute delayed images. The MDME sequence immediately after contrast injection cannot fully reflect the effects of gadolinium-based contrast agent leakage in the tissue.

Radiology, Nuclear Medicine and ImagingMedicine
10
Article|23 citations·2021
Differentiation between glioblastoma and primary CNS lymphoma: application of DCE-MRI parameters based on arterial input function obtained from DSC-MRI
Koung Mi Kang, Seung Hong Choi, Park Chul-Kee, Tae Min Kim, Sung‐Hye Park, Joo Ho Lee, Soon‐Tae Lee, Inpyeong Hwang, Roh‐Eul Yoo, Tae Jin Yun, Ji‐hoon Kim, Chul‐Ho Sohn
SJR Q1European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
11
Article|21 citations·2012
Coronary Vasospastic Angina: Assessment by Multidetector CT Coronary Angiography
Koung Mi Kang, Sang Il Choi, Eun Ju Chun, Jeong‐Ah Kim, Tae‐Jin Youn, Dong‐Ju Choi
SJR Q1Korean Journal of RadiologyOA

OBJECTIVE: We aimed to describe the imaging findings of multidetector CT coronary angiography (MDCTA) in cases of vasospastic angina (VA) and to determine the accuracy of MDCTA in the identification of VA as compared with invasive coronary angiography with an ergonovine provocation test (CAG with an EG test). MATERIALS AND METHODS: Fifty-three patients with clinically suspected VA were enrolled in this study. Two radiologists analyzed the stenosis degree, presence or absence of plaque, plaque co

Radiology, Nuclear Medicine and ImagingMedicine
12
Article|21 citations·2016
Application of Cardiac Gating to Improve the Reproducibility of Intravoxel Incoherent Motion Measurements in the Head and Neck
Koung Mi Kang, Seung Hong Choi, Dong‐Eun Kim, Tae Jin Yun, Ji‐hoon Kim, Chul‐Ho Sohn, Sun‐Won Park
SJR Q1Magnetic Resonance in Medical SciencesOA

4b gating was more reproducible with respect to measurements of IVIM parameters in comparison with 4b or 17b.

Radiology, Nuclear Medicine and ImagingMedicine
13
Article|17 citations·2005
중등 예비 생물 교사들의 생명공학에 대한 인식 조사
강경미, 김희백

The purpose of this study was to investigate preservice secondary biology teachers' understanding of biotechnology. Most preservice teachers have heard about biotechnology and they have high recognition about usefulness rather than danger of biotechnology such as genetically modified food, genetically modified animal for medical treatment, genetic test, gene therapy, etc. They have relatively lower understanding about genetic test that have caused social controversy recently than other topics. T

14
Article|16 citations·2020
<p>Prediction of Amyloid Positivity in Mild Cognitive Impairment Using Fully Automated Brain Segmentation Software</p>
Koung Mi Kang, Chul‐Ho Sohn, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Roh‐Eul Yoo, Tae Jin Yun, Seung Hong Choi
SJR Q2Neuropsychiatric Disease and TreatmentOA

Relative hippocampal volume measures provided by automated brain segmentation software can be useful for screening cerebral Aβ positivity in clinical practice for patients with amnestic MCI. The information may also help clinicians interpret structural MRI to predict outcomes and determine early intervention for delaying the progression to Alzheimer's disease dementia.

Psychiatry and Mental healthMedicine
15
Article|11 citations·2022
Enlarged perivascular spaces are associated with decreased brain tau deposition
Koung Mi Kang, Min Soo Byun, Dahyun Yi, Kyung Hoon Lee, Min Jung Kim, Hye‐Jin Ahn, Gijung Jung, Jun‐Young Lee, Yu Kyeong Kim, Yun‐Sang Lee, Chul‐Ho Sohn, Dong Young Lee
SJR Q1CNS Neuroscience & TherapeuticsOA

AIMS: The aim of this study was to investigate the associations of enlarged perivascular spaces (EPVS) in the basal ganglia (BG) and centrum semiovale (CSO) with beta-amyloid (Aβ) and tau deposition in older adults with a diverse cognitive spectrum. METHODS: F] AV-1451 PET, and MRI. EPVS in the BG and CSO and other small vessel disease markers, such as white matter hyperintensities, lacunes, and deep and lobar microbleeds, were assessed. RESULTS: Increased EPVS in the BG showed a significant ass

Cellular and Molecular NeuroscienceNeuroscience

Research Areas

Radiology, Nuclear Medicine and ImagingPsychiatry and Mental healthGeneticsPhysiologyEndocrinology, Diabetes and MetabolismEpidemiology

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