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Kyung-eun Han

Ewha Womans University · Medicine

About the Lab

Professor Kyung-eun Han's research lab specializes in ophthalmic translational medicine, focusing on corneal diseases, ocular surface disorders, and regenerative therapies. The lab investigates genetic factors in corneal dystrophies, such as GCD2, and explores novel treatments for corneal injuries using human-derived biological agents like amniotic membrane and serum. Key research directions include the pathogenesis of corneal neovascularization, the development of safe and effective electrosurgical techniques for lymphangiectasis, and the preclinical evaluation of regenerative therapies in animal models of alkali burns. The lab emphasizes precision medicine through genetic analysis and longitudinal clinical evaluation.

corneal dystrophyocular surface diseaseregenerative ophthalmologycorneal alkali injuryhuman-derived therapies

Research Overview

Papers
98
Total Citations
713
Papers (5y)
25
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
25total
2022
2023
2024
2025
2026
Citations per year (5y)
33total
20222023202420252026

Selected Papers

15
1
Article|187 citations·2014
Evaluation of Dry Eye and Meibomian Gland Dysfunction After Cataract Surgery
Kyung Eun Han, Sangchul Yoon, Ji Min Ahn, Sang Min Nam, R. Doyle Stulting, Eung Kweon Kim, Kyoung Yul Seo
SJR Q1American Journal of OphthalmologyOA
Public Health, Environmental and Occupational HealthMedicine
2
Review|117 citations·2015
Pathogenesis and treatments of TGFBI corneal dystrophies
Kyung Eun Han, Seung‐il Choi, Tae‐im Kim, Yong‐Sun Maeng, R. Doyle Stulting, Yong Woo Ji, Eung Kweon Kim
SJR Q1Progress in Retinal and Eye ResearchOA
Radiology, Nuclear Medicine and ImagingMedicine
3
Article|48 citations·2018
Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea National Health and Nutrition Examination Survey, 2008–2011
Kyung Eun Han, Seunghee Baek, Seung‐Hyun Kim, Key Hwan Lim
SJR Q1PLoS ONEOA

This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.

Pathology and Forensic MedicineMedicine
4
Review|33 citations·2010
Clinical Findings and Treatments of Granular Corneal Dystrophy Type 2 (Avellino Corneal Dystrophy): A Review of the Literature
Kyung Eun Han, Tae‐im Kim, Woosuk Chung, Seung‐il Choi, Bong-Yoon Kim, Eung Kweon Kim
SJR Q2Eye & Contact Lens Science & Clinical PracticeOA

Perfect treatment of exacerbation after corneal surface ablation does not exist until now. To prevent exacerbation, refractive surgeons must do a careful preoperative examination of candidates in refractive surgeries.

Radiology, Nuclear Medicine and ImagingMedicine
5
Article|24 citations·2015
Extremely varied phenotypes in granular corneal dystrophy type 2 heterozygotes
Kyung Eun Han, Seung‐il Choi, Woosuk Chung, Se Hwan Jung, Nicholas Katsanis, Tae‐im Kim, Eung Kweon Kim
PubMedOA

GCD2 heterozygotes have extremely varied phenotypes between individual patients. However phenotypes were broadly consistent within families, suggesting that the observed variable expressivity might be regulated by other genetic factors that could influence the abundance of TGFBIp or the function of the pathway. From a clinical perspective, our data also highlighted that genetic analysis and meticulous slit-lamp examination in both eyes at multiple time intervals is necessary.

Radiology, Nuclear Medicine and ImagingMedicine
6
Article|17 citations·2012
Removal of Lymphangiectasis Using High-Frequency Radio Wave Electrosurgery
Kyung Eun Han, Chul Young Choi, Kyoung Yul Seo
SJR Q1CorneaOA

High-frequency radio wave electrosurgery may be a safe, quick, and effective modality for the treatment of symptomatic lymphangiectasis patients.

SurgeryMedicine
7
Article|15 citations·2013
Comparison of intraocular pressures after myopic laser-assisted subepithelial keratectomy: Tonometry-pachymetry, Goldmann applanation tonometry, dynamic contour tonometry, and noncontact tonometry
Kyung Eun Han, Hye‐Sun Kim, Chan Yun Kim, Ikhyun Jun, Eung Kweon Kim, Tae‐im Kim
SJR Q1Journal of Cataract & Refractive SurgeryOA

No author has a financial or proprietary interest in any material or method mentioned.

Radiology, Nuclear Medicine and ImagingMedicine
8
Article|13 citations·2019
Therapeutic effects of three human-derived materials in a mouse corneal alkali burn model*
Kyung Eun Han, Mi Hye Park, Kyoung Hye Kong, Euno Choi, Kyu‐Ryong Choi, Roo Min Jun
SJR Q3Cutaneous and Ocular ToxicologyOA

<b>Purpose:</b> To compare the therapeutic effects of human derivatives in a mouse alkali burn model. <b>Methods:</b> The right eyes of mice were injured using NaOH. After alkali injury, one of the following agents was topically administered for 7 d: human amniotic membrane (hAM) suspension, human umbilical cord serum (hUCS), and human peripheral blood serum (hPBS), or saline. The epithelial defect areas on days 1, 2, and 3 degrees of opacity on days 2, 3, and 7, and corneal neovascularization (

Radiology, Nuclear Medicine and ImagingMedicine
9
Article|13 citations·2012
Changes of Clinical Manifestation of Granular Corneal Deposits Because of Recurrent Corneal Erosion in Granular Corneal Dystrophy Types 1 and 2
Kyung Eun Han, Woosuk Chung, Terry Kim, Kyu Seo Kim, Tae‐im Kim, Eung Kweon Kim
SJR Q1CorneaOA

The disappearance of granular deposits in GCD1 and GCD2 could be interpreted as evidence of drop-off phenomena with recurrent corneal erosion. With drop off of the deposits, various configurations and morphological changes of corneal deposits can occur in these corneal dystrophies.

SurgeryMedicine
10
Article|11 citations·2012
Successful argon laser photocoagulation of diffuse epithelial ingrowth following concomitant persistent pupillary membrane removal and phacoemulsification
Kyung Eun Han, Chan Yun Kim, Jae Lim Chung, Jin Pyo Hong, Bradford Sgrignoli, Eung Kweon Kim
SJR Q1Journal of Cataract & Refractive Surgery

No author has a financial or proprietary interest in any material or method mentioned.

OphthalmologyMedicine
11
Article|11 citations·2013
Epithelial Wound Healing after Cataract Surgery Comparing Two Different Topical Fluoroquinolones
Kyung Eun Han, Woosuk Chung, Tae‐im Kim, Sekyung Kim, Terry Kim, Eung Kweon Kim
SJR Q2Yonsei Medical JournalOA

There were no differences on epithelial wound healing comparing these two different fluoroquinolones at the incision site of cataract surgery.

OphthalmologyMedicine
12
Article|9 citations·2020
Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis
Seung Min Lee, Roo Min Jun, Kyu‐Ryong Choi, Kyung Eun Han
SJR Q1American Journal of Ophthalmology
Public Health, Environmental and Occupational HealthMedicine
13
Article|8 citations·2012
Discrepancies between parental reports and clinical diagnoses of strabismus in Korean children
Kyung Eun Han, Key Hwan Lim
SJR Q2Journal of American Association for Pediatric Ophthalmology and Strabismus
Pathology and Forensic MedicineMedicine
14
Article|8 citations·2018
Conjunctival Flap with Biodegradable Collagen Matrix Implantation for the Treatment of Scleromalacia after Periocular Surgery
Kyung Eun Han, Sangchul Yoon, Roo Min Jun, Tae‐im Kim, Eung Kweon Kim, Kyoung Yul Seo
SJR Q2Ocular Immunology and InflammationOA

<i>Purpose</i>: To report a new surgical procedure using biodegradable collagen matrix (Ologen) implantation with conjunctival flap for reconstruction of scleromalacia after periocular surgery. <i>Methods</i>: A total of 26 areas of 25 eyes in 25 patients were included. We divided all eyes according to the preoperative extent of calcified plaque or scleral defect as follows: small, large, and large and severe. Morphologic outcomes were graded from 0 to 7, with higher scores indicating worse cosm

DermatologyMedicine
15
Article|5 citations·2022
Ocular Surface and Tear Cytokine Changes after Cataract Surgery in Patients with Type 2 Diabetes
Ahyoung Kim, Ji Young Moon, Roo Min Jun, Hyun Jin Kim, Kyung Eun Han
SJR Q2Ocular Immunology and Inflammation

Diabetic patients can experience more prominent changes after surgery and these changes were accompanied by an increase of several tear cytokines.

Public Health, Environmental and Occupational HealthMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingOphthalmologyPublic Health, Environmental and Occupational HealthEpidemiologyMolecular BiologyPathology and Forensic Medicine

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