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Kyungjun Cha

Hanyang University · Medicine

About the Lab

Professor Kyungjun Cha's research lab specializes in biomedical signal analysis, stem cell biology, and advanced materials characterization using spectroscopic and statistical methods. The lab focuses on developing innovative diagnostic tools and predictive models for liver fibrosis, fetal heart rate monitoring, and plant (rice) classification through Raman spectroscopy and machine learning. It also explores noise reduction in engineering systems using statistical design and signal processing techniques. The integration of bioinformatics, biophysics, and data-driven modeling defines the lab’s interdisciplinary approach.

biomedical signal processingstem cell genomicsRaman spectroscopydiagnostic modelingnoise reduction engineering

Research Overview

Papers
127
Total Citations
631
Papers (5y)
15
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
15total
2018
2020
2021
2023
2024
Citations per year (5y)
142total
20182020202120232024

Selected Papers

15
1
Article|108 citations·2002
Kriging interpolation methods in geostatistics and DACE model
Je-Seon Ryu, Min-Soo Kim, Kyung‐Joon Cha, Tae Hee Lee, Donghoon Choi
KSME International Journal
Computational Theory and MathematicsComputer Science
2
Article|62 citations·2013
Random forest as a potential multivariate method for near-infrared (NIR) spectroscopic analysis of complex mixture samples: Gasoline and naphtha
Sanguk Lee, Hangseok Choi, Kyung‐Joon Cha, Hoeil Chung
SJR Q1Microchemical Journal
Analytical ChemistryChemistry
3
Article|51 citations·2006
Profiling of Differentially Expressed Genes in Human Stem Cells by cDNA Microarray
김철근, 이종주, 정대영, 전진선, 허현석, 강호철, 신준호, 조윤신, 차경준, 김찬길, 도병록, 김경숙

Stem cells are unique cell populations with the ability to undergo both self-renewal and differentiation, although a wide variety of adult stem cells as well as embryonic stem cells have been identified and stem cell plasticity has recently been reported. To identify genes implicated in the control of the stem cell state as well as the characteristics of each stem cell line, we analyzed the expression profiles of genes in human embryonic, hematopoietic (CD34+ and CD133+), and mesenchymal stem ce

4
Article|46 citations·2020
Incorporation of two-dimensional correlation analysis into discriminant analysis as a potential tool for improving discrimination accuracy: Near-infrared spectroscopic discrimination of adulterated olive oils
Woosuk Sohng, Yeonju Park, Daeil Jang, Kyung‐Joon Cha, Young Mee Jung, Hoeil Chung
SJR Q1Talanta
Analytical ChemistryChemistry
5
Review|43 citations·2000
Freezing immature oocytes
Kyung‐Joon Cha, Hyung‐Min Chung, Jeong Mook Lim, J.J. Ko, S. Han, Dong Hee Choi, T.K. Yoon
SJR Q1Molecular and Cellular Endocrinology
Public Health, Environmental and Occupational HealthMedicine
6
Article|33 citations·2018
Improving the accuracy of spectroscopic identification of geographical origins of agricultural samples through cooperative combination of near-infrared and laser-induced breakdown spectroscopy
Changhwan Eum, Daeil Jang, Jonghyun Kim, Sanghoi Choi, Kyung‐Joon Cha, Hoeil Chung
SJR Q2Spectrochimica Acta Part B Atomic Spectroscopy
Mechanics of MaterialsEngineering
7
Article|29 citations·2008
Improving Raman spectroscopic differentiation of the geographical origin of rice by simultaneous illumination over a wide sample area
Yongdan Kim, Sanguk Lee, Hoeil Chung, Hangseok Choi, Kyung‐Joon Cha
SJR Q2Journal of Raman Spectroscopy

Abstract This research substantially improved the differentiation of rice of two geographical origins utilizing a wide area illumination (WAI) scheme capable of collecting Raman spectra of a large sample area (28.3 mm 2 ) synchronously without sample rotation. For the purposes of comparison, we also employed a conventional scheme in which the laser illuminated only small areas. Principal component analysis (PCA) was used to differentiate the two geographical origins using the Raman spectra colle

Analytical ChemistryChemistry
8
Article|18 citations·2005
Pregnancies From Cryopreserved Oocytes Using Vitrification Protocol
T. Kim, Seung Wook Hong, Kyung‐Joon Cha
SJR Q1Fertility and Sterility
Public Health, Environmental and Occupational HealthMedicine
10
Article|12 citations·2020
Alternative selection of Raman or LIBS spectral information in hierarchical discrimination of raw sapphires according to geographical origin for accuracy improvement
Changhwan Eum, Daeil Jang, Siwon Lee, Kyung‐Joon Cha, Hoeil Chung
SJR Q1Talanta
Mechanics of MaterialsEngineering
11
Article|9 citations·2004
The Optimal Design for Low Noise Intake System Using Kriging Method with Robust Design
Kyung‐Joon Cha, Chung-Un CHIN, Je-Seon Ryu, Jae‐Eung Oh
JSME International Journal Series COA

This paper proposes an optimal design scheme to improve an intake's capacity of noise reduction of the exhaust system by combining the Taguchi and Kriging method. As a measuring tool for the performance of the intake system, the performance prediction software which is developed by Oh, Lee and Lee (1996) is used. In the first stage, the length and radius of each component of the current intake system are selected as control factors. Then, the L18 table of orthogonal arrays is adapted to extract

Computational Theory and MathematicsComputer Science
12
Article|9 citations·2018
Discrimination of phthalate species using a simple phage-based colorimetric sensor in conjunction with hierarchical support vector machine
Daun Seol, Daeil Jang, Jin‐Woo Oh, Kyung‐Joon Cha, Hoeil Chung
SJR Q1Environmental ResearchOA
Biomedical EngineeringEngineering
13
Article|6 citations·2024
Modified FIB-4 Index in Type 2 Diabetes Mellitus with Steatosis: A Non-Linear Predictive Model for Advanced Hepatic Fibrosis
Jonghyun Kim, Takanori Ito, Taeang Arai, Masanori Atsukawa, Miwa Kawanaka, Hidenori Toyoda, Takashi Honda, Ming‐Lung Yu, Eileen L. Yoon, Dae Won Jun, Kyung‐Joon Cha, Mindie H. Nguyen
SJR Q2DiagnosticsOA

Background: The Fibrosis-4 (FIB-4) index is widely recommended as a first-tier method for screening advanced hepatic fibrosis; however, its diagnostic performance is known to be suboptimal in patients with Type 2 diabetes mellitus (T2DM). We aim to propose a modified FIB-4, using the parameters of the existing FIB-4, tailored specifically for diabetic patients with metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: A total of 1503 patients who underwent liver biopsy were

EpidemiologyMedicine
14
Article|6 citations·2018
Classification of acoustic noise signals using wavelet spectrum based support vector machine
차경준, 유국현, 이진욱, 문병민, 배석주

Harsh noises come from air-conditioning units are chronic complaining issues to their users. Individual perceptions of noise levels have been generally quantified by means of subjective evaluation such as a jury test. This article proposes a classification approach to acoustic noise signals using a wavelet spectrum analysis. We derive energy spectrums of noise signals using a discrete wavelet transform at pre-specified window length. The energy spectrums are a linear form and represented by a Hu

15
Article|5 citations·2015
Robust estimation of support vector regression via residual bootstrap adoption
Won-Young Choi, Dong-Hoon Choi, Kyung‐Joon Cha
SJR Q2Journal of Mechanical Science and Technology
Computational Theory and MathematicsComputer Science

Research Areas

Public Health, Environmental and Occupational HealthMolecular BiologyComputational Theory and MathematicsAnalytical ChemistryPediatrics, Perinatology and Child HealthGenetics

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