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Kyuram Cho

Korea University · Medicine

About the Lab

Professor Kyuram Cho's research lab specializes in diagnostic radiology and medical imaging, with a focus on improving the early detection and characterization of breast cancer using advanced imaging techniques. The lab investigates the diagnostic value of mammography, ultrasound, diffusion-weighted MRI (DWI), and dynamic contrast-enhanced MRI (DCE-MRI), particularly in challenging cases such as non-calcified ductal carcinoma in situ (DCIS). Key research directions include correlating radiological findings with histopathological features, evaluating perfusion parameters via intravoxel incoherent motion (IVIM) modeling, and leveraging computer-aided diagnosis (CAD) to enhance diagnostic accuracy and treatment planning.

breast cancer imagingnon-calcified DCISDWI and DCE-MRIIVIM perfusionradiological-histological correlation

Research Overview

Papers
140
Total Citations
1,608
Papers (5y)
26
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
26total
2022
2023
2024
2025
2026
Citations per year (5y)
127total
20222023202420252026

Selected Papers

15
1
Article|50 citations·2004
A comparative study of 2D and 3D ultrasonography for evaluation of solid breast masses
Kyu Ran Cho, Bo Kyoung Seo, Juneyoung Lee, Etta D. Pisano, Bo‐Kyung Je, Ji Young Lee, Eun Jeong Choi, Kyoo Byung Chung, Yu Whan Oh
SJR Q1European Journal of Radiology
Pathology and Forensic MedicineMedicine
2
Article|36 citations·2008
Non-Calcified Ductal Carcinoma in Situ: Ultrasound and Mammographic Findings Correlated with Histological Findings
Kyu Ran Cho, Bo Kyoung Seo, Chul Hwan Kim, Kyu Won Whang, Yun Hwan Kim, Baek Hyun Kim, Ok Hee Woo, Young Hen Lee, Kyoo Byung Chung
SJR Q2Yonsei Medical JournalOA

Diagnosis of non-calcified DCIS by mammography is not an easy task due to the lack of typical malignant calcifications or masses. High resolution ultrasound can be useful for detecting non-calcified DCIS, and ultrasound findings are correlated with histological features.

Pathology and Forensic MedicineMedicine
3
Article|35 citations·2018
Intravoxel incoherent motion diffusion‐weighted MRI of invasive breast cancer: Correlation with prognostic factors and kinetic features acquired with computer‐aided diagnosis
Sung Eun Song, Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Kyong Hwa Park, Yo Han Son, Robert Grimm
SJR Q1Journal of Magnetic Resonance Imaging

BACKGROUND: As both intravoxel incoherent motion (IVIM) modeling and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provide perfusion parameters, IVIM-derived perfusion parameters might be expected to correlate with the kinetic features from DCE-MRI. PURPOSE: To investigate the association between IVIM parameters and prognostic factors and to evaluate the correlation between IVIM parameters and kinetic features in invasive breast cancer patients using computer-aided diagnosis (CA

Radiology, Nuclear Medicine and ImagingMedicine
4
Article|35 citations·2017
Additional value of diffusion-weighted imaging to evaluate multifocal and multicentric breast cancer detected using pre-operative breast MRI
Sung Eun Song, Eunkyung Park, Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Seung Pil Jung, Sung Bum Cho
SJR Q1European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
5
Article|34 citations·2016
Significance of Additional Non-Mass Enhancement in Patients with Breast Cancer on Preoperative 3T Dynamic Contrast Enhanced MRI of the Breast
Yun Hee Cho, Kyu Ran Cho, Eun Kyung Park, Bo Kyoung Seo, Ok Hee Woo, Sung Bum Cho, Jeoung Won Bae
SJR Q4Iranian Journal of RadiologyOA

The possibility of malignancy is strongly indicated when additional NME lesions show linear or segmental enhancement on preoperative 3T DCE-MRI in patients with recently diagnosed breast cancer.

Radiology, Nuclear Medicine and ImagingMedicine
6
Article|33 citations·2016
Additional Value of Diffusion-Weighted Imaging to Evaluate Prognostic Factors of Breast Cancer: Correlation with the Apparent Diffusion Coefficient
Eunkyung Park, Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Sung Bum Cho, Jeoung Won Bae
SJR Q4Iranian Journal of RadiologyOA

The pre-operative use of the 3.0 Tesla DWI could provide information about the lymph node status and tumor proliferation for breast cancer patients, and could help determine the optimal treatment plan.

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|32 citations·2021
Machine learning with multiparametric breast MRI for prediction of Ki-67 and histologic grade in early-stage luminal breast cancer
Sung Eun Song, Kyu Ran Cho, Yongwon Cho, Kwangsoo Kim, Seung Pil Jung, Bo Kyoung Seo, Ok Hee Woo
SJR Q1European Radiology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
Article|24 citations·2008
Non-Calcified Ductal Carcinoma in Situ: Ultrasound and Mammographic Findings Correlated with Histological Findings
조규란, 서보경, 김철환, 황규원, 김윤환, 김백현, 우옥희, 이영흔, 정규병
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120080490010103

Purpose: To evaluate radiological findings of non-calcified ductal carcinoma in situ (DCIS) and to correlate those with histological features. Materials and Methods: From July 2002 to March 2006, 22 patients with histologically-proven non- calcified DCIS were included. Mammography was obtained in 19 patients, ultrasound in 18 patients, and both examinations in 15 patients. Radiological findings were evaluated according to the Breast Imaging Reporting and Data System by American College of Radiol

9
Article|21 citations·2016
Breast Cancer Detection in a Screening Population: Comparison of Digital Mammography, Computer-Aided Detection Applied to Digital Mammography and Breast Ultrasound
Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Sung Eun Song, Jungsoon Choi, Shin Young Whang, Eun Kyung Park, Ah Young Park, Hyeseon Shin, Hwan Hoon Chung
SJR Q2Journal of Breast CancerOA

For breast cancer screening, breast US alone is satisfactory for all age groups, although FFDM+ CAD+US is the perfect screening method. Patient age, breast composition, and pathological tumor size and type may influence cancer detection during screening.

Artificial IntelligenceComputer Science
10
Article|11 citations·2016
Breast Cancer Detection in a Screening Population: Comparison of Digital Mammography, Computer-Aided Detection Applied to Digital Mammography and Breast Ultrasound
조규란, 서보경, 우옥희, 송성은, 최정순, 황신영, 박은경, 박아영, 신혜선, 정환훈
Journal of Breast Cancer

Purpose: We aimed to compare the detection of breast cancer using full-field digital mammography (FFDM), FFDM with computer-aided detection (FFDM+CAD), ultrasound (US), and FFDM+CAD plus US (FFDM+CAD+US), and to investigate the factors affecting cancer detection. Methods: In this retrospective study conducted from 2008 to 2012, 48,251 women underwent FFDM and US for cancer screening. One hundred seventy-one breast cancers were detected: 115 invasive cancers and 56 carcinomas in situ. Two radiolo

11
Article|9 citations·2016
Radiologic Findings of Metastatic Malignant Melanoma of the Breast: Mammographic, Sonographic, Dynamic Contrast-Enhanced Breast MRI, and 18F-FDG PET-CT Features
Youyeon Kim, Kyu Ran Cho, Bo Kyoung Seo, Ok Hee Woo, Jeong Hyun Lee, Sung Bum Cho
SJR Q4Iranian Journal of RadiologyOA

: Metastatic involvement of the breast from an extra-mammary tumor is rare. However, when a patient with a known primary malignancy complains of a palpable breast mass, both the primary breast cancer and the metastatic lesion must be considered as a differential diagnosis. Melanoma is one of the tumors that commonly metastasizes to the breast, but the characteristic imaging features are not well known. Therefore, an understanding of the characteristic image findings for melanoma would be advanta

OncologyMedicine
12
Article|7 citations·2010
Sonographic Findings of Mammary Duct Ectasia: Can Malignancy be Differentiated from Benign Disease
조규란, 김금원, 서보경, 황규원, 우옥희, 오유환, 김윤환, 배정원, 박용성, 황철목, 이무식, 김광일
Journal of Breast Cancer

Purpose: This study was designed to investigate differences in ultrasonographic findings between malignant and benign mammary duct ectasia. Methods: From January 2003 to June 2005, 54 surgically proven mammary duct ectasia lesions depicted on sonograms were included in this study. We evaluated the ultrasonographic (US) findings in terms of involved ductal location, size, margin, intraductal echogenicity, presence of an intraductal nodule, calcification, ductal wall thickening and echo changes of

13
Article|5 citations·2010
Primary Peripheral T-cell Lymphoma of the Breast: Radiologic and Pathologic Findings
조규란, 임현주, 김인선, 황규원, 서보경, 우옥희, 오유환, 배정원
Journal of Breast Cancer

Primary breast lymphoma is a rare disease entity, particularly the T-cell type. There have been many case reports of primary breast lymphomas; however, these are mostly pathologic reports, with only a few reports in radiology literature. To the best of our knowledge, this is the first report on the radiologic features of primary T-cell type breast lymphoma, including mammography, ultrasonography, MR imaging, and 18 fluorodeoxyglucose positron emission tomography/computed tomography scan. The rad

14
Article|4 citations·2002
Spiral CT Findings of Chromophobe Renal Cell Carcinoma: Correlation with Pathologic Features and Prognosis
Kyu Ran Cho, Cheol Min Park, Hwan Hoon Chung, Hyoung Rae Kim, Bum Jin Park, Young Hen Lee, Bo Kyeong Seo, Sang Hoon, Chang Hee Lee, Kyoo Byung Chung
Journal of the Korean Radiological Society

Purpose: To describe the spiral CT findings of CRCC and to correlate these with the pathologic features, nuclear grading, tumor staging, and prognosis. Materials and Methods: We encountered eleven cases of CRCC among 167 cases of histopathologically proven RCC, retrospectively evaluating the spiral CT findings of CRCC including tumor size, internal texture, attenuation, margin, and the involvement of veins or lymph nodes. In addition, the CT findings were correlated with the pathologic features,

Pulmonary and Respiratory MedicineMedicine
15
Article|3 citations·2008
A Comparative Study of Palpable and Nonpalpable Breast Cancers determined by Ultrasonography
Kyu Ran Cho, Bo Kyoung Seo, Juneyoung Lee, Ki Yeol Lee, Bo‐Kyung Je, Baek Hyun Kim, Sang Hoon, Yu Whan Oh, Seokjin Kim, Jeoung Won Bae
SJR Q2Journal of Breast CancerOA

Purpose: The aim of this study was to investigate any difference of ultrasound findings for palpable and nonpalpable breast cancers. Methods: Two hundred breast cancer patients that had undergone preoperative ultrasound and surgery were enrolled in the study. A total of 126 cancers were palpable, and the remaining 74 cancers were nonpalpable. We compared lesion characteristics using ultrasound images according to the BI-RADS� -Ultrasound guidelines of the American College of Radiology. A crude o

Pathology and Forensic MedicineMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingPathology and Forensic MedicinePulmonary and Respiratory MedicineCancer ResearchSurgeryArtificial Intelligence

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