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Lee Yongsung

Yonsei University · Medicine

About the Lab

Professor Lee Yongsung's research lab specializes in urological surgery and regenerative medicine, focusing on innovative surgical techniques for complex urological conditions such as ectopic ureteroceles and horseshoe kidney tumors. The lab also explores cutting-edge regenerative approaches using exosomes and ultrasound-mediated reprogramming to convert fibroblasts into neural progenitor cells. Additionally, the lab investigates pediatric urology, including renal function assessment via ultrasonography and the impact of orofacial disorders on oral health-related quality of life.

urological surgeryexosome-mediated reprogrammingregenerative medicinepediatric urologyultrasonography in renal function

Research Overview

Papers
162
Total Citations
1,395
Papers (5y)
29
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
29total
2022
2023
2024
2025
2026
Citations per year (5y)
81total
20222023202420252026

Selected Papers

15
1
Article|57 citations·2015
Superb microvascular imaging for the detection of parenchymal perfusion in normal and undescended testes in young children
Yong Seung Lee, Myung‐Joon Kim, Sang Won Han, Hye Sun Lee, Young-Jae Im, Hyun Joo Shin, Mi‐Jung Lee
SJR Q1European Journal of RadiologyOA
SurgeryMedicine
2
Article|38 citations·2012
Factors Associated with Complications of the Ureteral Stump After Proximal Ureteroureterostomy
Yong Seung Lee, Yoon Soo Hah, Myung‐Joon Kim, Hyun Jin Jung, Mi‐Jung Lee, Young Jae Im, Sang Won Han
SJR Q1The Journal of Urology

PURPOSE: Ureteroureterostomy is a treatment modality for managing an ectopic ureterocele or ectopic ureter and preserving upper pole kidney function. However, the development of urinary tract infection at the residual ureteral stump is a concern. We analyzed factors affecting the development of urinary tract infection at the residual ureteral stump after proximal ureteroureterostomy. MATERIALS AND METHODS: Between January 2002 and December 2009 proximal ureteroureterostomy was performed in 80 pa

Pediatrics, Perinatology and Child HealthMedicine
3
Article|37 citations·2018
Efficacy and safety of mirabegron, a β3-adrenoceptor agonist, for treating neurogenic bladder in pediatric patients with spina bifida: a retrospective pilot study
Jee Soo Park, Yong Seung Lee, Cho Nyeong Lee, Sung Hoon Kim, Sang Woon Kim, Sang Won Han
SJR Q1World Journal of UrologyOA
UrologyMedicine
4
Article|28 citations·2019
Robot-assisted laparoscopic single-port pyeloplasty using the da Vinci SP® system: initial experience with a pediatric patient
Sung Ku Kang, Won Sik Jang, Sang Woon Kim, Sung Hoon Kim, Sang Won Han, Yong Seung Lee
SJR Q2Journal of Pediatric UrologyOA
SurgeryMedicine
5
Article|25 citations·2010
The feasibility of solo-surgeon living donor nephrectomy: initial experience using video-assisted minilaparotomy surgery
Yong Seung Lee, Hwang Gyun Jeon, Seung Ryeol Lee, Woo Ju Jeong, Seung Choul Yang, Woong Kyu Han
SJR Q1Surgical EndoscopyOA
Public Health, Environmental and Occupational HealthMedicine
6
Article|23 citations·2018
Exosome-Mediated Ultra-Effective Direct Conversion of Human Fibroblasts into Neural Progenitor-like Cells
Yong Seung Lee, Woon Yong Jung, Hyejung Heo, Min Geun Park, Seung-Hun Oh, Byong-Gon Park, Soonhag Kim
SJR Q1ACS Nano

Exosomes, naturally secreted nanoparticles, have been introduced as vehicles for horizontal transfer of genetic material. We induced autologous exosomes containing a cocktail of reprogramming factors ("reprosomes") to convert fibroblasts into neural progenitor cells (NPCs). The fibroblasts were treated with ultrasound and subsequently cultured in neural stem cell medium for 1 day to induce the release of reprosomes composed of reprogramming factors associated with chromatin remodeling and neural

Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|22 citations·2015
Complications After Common Sheath Reimplantation in Pediatric Patients With Complicated Duplex System
Yong Seung Lee, Young Jae Im, Sang Hee Shin, Rosito T. Bascuna, Ji Yong Ha, Sang Won Han
SJR Q2UrologyOA
UrologyMedicine
8
Article|20 citations·2013
The risk factors and clinical significance of acute postoperative complications after unstented pediatric pyeloplasty: A single surgeon’s experience
Yong Seung Lee, Cho Nyeong Lee, Myung Up Kim, Won Sik Jang, Hyeyoung Lee, Young Jae Im, Sang Won Han
SJR Q1Journal of Pediatric SurgeryOA
Pediatrics, Perinatology and Child HealthMedicine
9
Article|16 citations·2017
An ultra-effective method of generating extramultipotent cells from human fibroblasts by ultrasound
Yong Seung Lee, Hyejung Heo, Jong‐Hwan Lee, Sung Ung Moon, Woon Yong Jung, YongKeun Park, Min Geun Park, Seung‐Hun Oh, Soonhag Kim
SJR Q1BiomaterialsOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|15 citations·2015
Is Increased Echogenicity Related to a Decrease in Glomerular Filtration Rate? Objective Measurements in Pediatric Solitary Kidney Patients—A Retrospective Analysis
Yong Seung Lee, Mi‐Jung Lee, Myung‐Joon Kim, Young Jae Im, Sang Woon Kim, Neddy Lee Lim, Sang Won Han
SJR Q1PLoS ONEOA

Quantitative measurements of renal echogenicity using a graphic program show close correlation with renal histology in adult patients, but this has neither been applied in pediatric patients nor correlated with glomerular filtration rate (GFR). To determine the direct relationship between echogenicity and GFR, we retrospectively analyzed 91 patients with a solitary functioning kidney under the age of 10, who underwent ultrasonography and serum cystatin C evaluation on a single day between Januar

Pediatrics, Perinatology and Child HealthMedicine
11
Article|15 citations·2015
The vagaries of proper imaging in diagnosing single-system ectopic ureter in children with continuous incontinence and outcomes of simple nephrectomy
Yong Seung Lee, Young Jae Im, Sang Woon Kim, Myung‐Joon Kim, Mi‐Jung Lee, Neddy Lee Lim, Sang Won Han
SJR Q1Journal of Pediatric SurgeryOA
Pediatrics, Perinatology and Child HealthMedicine
12
Article|14 citations·2010
측두하악장애 환자에서 저작 효율 및 구강건강관련 삶의 질 평가
이용승, 안형준, 변영섭, 최종훈
Journal of Oral Medicine and Pain

본 연구에서는 최근 Sato 등이 고안한 mixing ability index(MAI)를 이용하여 측두하악장애 환자 중 통증이 있는 군과 무통성 관절잡음이 있는 군을 대상으로 객관적인 저작 효율을 정상인으로 구성된 대조군과 비교하고, 주관적인 평가 방법인 설문조사법 중에서 음식섭취가능지수(Food Intake Ability Index, FIA)와 저작 능력에 대한 주관적 인식도 평가(Visual Analogue Scale, VAS)를 이용하여 저작 효율을 평가하고, 구강건강과 관련된 삶의 질을 평가하기 위해 Oral Health Impact Profile(OHIP)-49K 설문조사를 시행하였다. 각 평가 방법 간의 상관성을 알아보고, 또한 통증군에 있어서는 치료 후 통증이 감소함에 따라 저작 효율의 변화 양상을 조사하여 다음과 같은 결과를 얻었다. 1. MAI, FIA, VAS는 통증군이 정상군에 비해 통계학적으로 유의하게 감소하였으며, 관절잡음군보다도 감소하여 통증군이 정상군과 관

13
Article|13 citations·2011
Retroperitoneoscopic Partial Nephrectomy in a Horseshoe Kidney
Yong Seung Lee, Ho Song Yu, Myung Up Kim, Ho Sung Jang, Dae Hun Lee, Chan Dong Yeom, Jong Ho Hwang, Won Sik Ham
Korean journal of urologyOA

A 21-year-old woman with a 4 cm enhancing cystic renal mass in the left moiety of a horseshoe kidney was treated through a retroperitoneal laparoscopic approach. The tumor was excised completely with cold scissors, and renal parenchyma suturing with a surgical bolster was done with Vicryl 2-0 sutures. Choosing the proper approach according to the location of the lesion and the surgeon's experience with both approaches are of importance in laparoscopic surgery in horseshoe kidney cases. A preoper

Pediatrics, Perinatology and Child HealthMedicine
14
Article|12 citations·2019
Transurethral incision as initial option in treatment guidelines for ectopic ureteroceles associated with duplex systems
Jee Soo Park, Yong Seung Lee, Cho Nyeong Lee, Sung Hoon Kim, Sang Woon Kim, Hyeyoung Lee, Sang Won Han
SJR Q1World Journal of UrologyOA
Pediatrics, Perinatology and Child HealthMedicine
15
Article|11 citations·2016
Can Hypertrophy of the Contralateral Testis Predict the Absence of a Viable Testis in Infancy with Cryptorchidism: A Prospective Analysis
Hee Seo Son, Yong Seung Lee, Young Jae Im, Sang Woon Kim, Byung Hoon, Sang Won Han
SJR Q1PLoS ONEOA

This prospective study aimed to evaluate whether Contralateral compensatory testicular hypertrophy (CTH) is valid as a predictive tool for a non-viable testis in children aged between 6 and 18 months, and whether CTH is affected by mini-puberty. Seventy-two testes from 60 boys aged between 6 and 18 months were categorized into three groups: 24 testes contralateral to surgically removed non-viable testes (NVTs), 24 testes contralateral to surgically corrected undescended testes (UDTs), and 24 tes

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

Pediatrics, Perinatology and Child HealthUrologyMolecular BiologySurgeryPublic Health, Environmental and Occupational HealthObstetrics and Gynecology

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