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Nam Hee Kim

Sungkyunkwan University · Medicine

About the Lab

Professor Nam Hee Kim's research lab focuses on environmental toxicology and metabolic disease epidemiology, with a particular emphasis on the health impacts of low-level heavy metal exposure—such as lead, mercury, and cadmium—on renal and liver function in the general population. The lab investigates the associations between environmental pollutants, biomarkers of exposure (e.g., blood and urinary levels), and chronic diseases like chronic kidney disease, nonalcoholic fatty liver disease (NAFLD), and pancreatic cancer. Using large-scale, nationally representative cohort data such as KNHANES and objective biomarkers like urinary cotinine, the lab aims to clarify controversial associations in environmental health science. Their work also extends to gastrointestinal oncology, particularly the role of tumor markers in colorectal neoplasia and cancer progression.

heavy metal toxicitychronic kidney diseasenonalcoholic fatty liver diseasepancreatic cancerenvironmental epidemiology

Research Overview

Papers
155
Total Citations
1,854
Papers (5y)
30
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2021
2022
2023
2024
2025
Citations per year (5y)
53total
20212022202320242025

Selected Papers

15
1
Article|188 citations·2015
Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population
Nam Hee Kim, Young Youl Hyun, Kyu‐Beck Lee, Yoosoo Chang, Seungho Rhu, Kook‐Hwan Oh, Curie Ahn
SJR Q2Journal of Korean Medical ScienceOA

Lead (Pb), mercury (Hg), and cadmium (Cd) are common heavy metal toxins and cause toxicological renal effects at high levels, but the relevance of low-level environmental exposures in the general population is controversial. A total of 1,797 adults who participated in the KNHANES (a cross-sectional nationally representative survey in Korea) were examined, and 128 of them (7.1%) had chronic kidney disease (CKD). Our study assessed the association between Pb, Hg, Cd exposure, and CKD. Blood Pb and

Health, Toxicology and MutagenesisEnvironmental Science
2
Article|158 citations·2017
Miss rate of colorectal neoplastic polyps and risk factors for missed polyps in consecutive colonoscopies
Nam Hee Kim, Yoon Suk Jung, Woo Shin Jeong, Hyo‐Joon Yang, Soo‐Kyung Park, Kyu-Yong Choi, Dong Il Park
SJR Q2Intestinal ResearchOA

One-quarter of neoplastic polyps was missed during colonoscopy. We encourage endoscopists to detect smaller and flat or sessile polyps by using the optimal withdrawal technique.

OncologyMedicine
3
Article|82 citations·2015
Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population
김남희, 현영열, 이규백, 장유수, 유승호, 오국환, 안규리
Journal of Korean Medical Science

Lead (Pb), mercury (Hg), and cadmium (Cd) are common heavy metal toxins and causetoxicological renal effects at high levels, but the relevance of low-level environmentalexposures in the general population is controversial. A total of 1,797 adults whoparticipated in the KNHANES (a cross-sectional nationally representative survey in Korea)were examined, and 128 of them (7.1%) had chronic kidney disease (CKD). Our studyassessed the association between Pb, Hg, Cd exposure, and CKD. Blood Pb and Cd l

4
Article|78 citations·2018
Prevalence of and Risk Factors for Colorectal Neoplasia in Asymptomatic Young Adults (20–39 Years Old)
Nam Hee Kim, Yoon Suk Jung, Hyo‐Joon Yang, Soo‐Kyung Park, Jung Ho Park, Dong Il Park, Chong Il Sohn
SJR Q1Clinical Gastroenterology and Hepatology
OncologyMedicine
5
Article|53 citations·2017
Serum CEA and CA 19-9 Levels are Associated with the Presence and Severity of Colorectal Neoplasia
Nam Hee Kim, Mi Yeon Lee, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyu-Yong Choi, Yoon Suk Jung
SJR Q2Yonsei Medical JournalOA

Both elevated serum CEA and CA 19-9 levels were associated with the presence of ACRN, as well as CRC. Elevated CEA levels were also associated with the presence of overall CRN. Moreover, both CEA and CA 19-9 levels were correlated with the severity of CRN.

Pulmonary and Respiratory MedicineMedicine
6
Article|51 citations·2018
Association between cotinine‐verified smoking status and risk of nonalcoholic fatty liver disease
Nam Hee Kim, Yoon Suk Jung, Hyun Pyo Hong, Jung Ho Park, Hong Joo Kim, Dong Il Park, Yong Kyun Cho, Chong Il Sohn, Woo Kyu Jeon, Byung Ik Kim
SJR Q1Liver International

BACKGROUND & AIMS: The relationship between cigarette smoking and nonalcoholic fatty liver disease (NAFLD) has been controversial. Most relevant studies have relied on self-reported questionnaires. We aimed to elucidate the association between smoking status and NAFLD using an objective biomarker of tobacco exposure (urinary cotinine) and self-reported questionnaire. METHODS: A cross-sectional study was conducted on 160 862 asymptomatic examinees who underwent abdominal ultrasonography and urina

EpidemiologyMedicine
7
Article|43 citations·2020
Glycemic Status, Insulin Resistance, and Risk of Pancreatic Cancer Mortality in Individuals With and Without Diabetes
Nam Hee Kim, Yoosoo Chang, Sung Ryol Lee, Seungho Ryu, Hong Joo Kim
SJR Q1The American Journal of Gastroenterology

INTRODUCTION: The impact of glycemic status and insulin resistance on the risk of pancreatic cancer in the nondiabetic population remains uncertain. We aimed to examine the association of glycemic status and insulin resistance with pancreatic cancer mortality in individuals with and without diabetes. METHODS: This is a cohort study of 572,021 Korean adults without cancer at baseline, who participated in repeat screening examinations which included fasting blood glucose, hemoglobin A1c, and insul

OncologyMedicine
8
Article|33 citations·2018
Preoperative risk factors for early recurrence in patients with resectable pancreatic ductal adenocarcinoma after curative intent surgical resection
Nam Hee Kim, Hong Joo Kim
SJR Q2Hepatobiliary & pancreatic diseases international
OncologyMedicine
9
Article|29 citations·2019
Long‐term efficacy and safety of CT‐P13, a biosimilar of infliximab, in patients with inflammatory bowel disease: A retrospective multicenter study
Nam Hee Kim, Ji Hyun Lee, Sung Noh Hong, Hyuk Yoon, Hyoun Woo Kang, Suck‐Ho Lee, Jong Pil Im, Jae Myung, Chang Soo Eun, Ji Won Kim, Chang Hwan Choi, Dong Il Park
SJR Q1Journal of Gastroenterology and Hepatology

Abstract Background and Aim A biosimilar of infliximab, CT‐P13 (Remsima®) has the potential to reduce treatment costs and enhance access to biological therapy for inflammatory bowel disease (IBD) patients. However, long‐term clinical data on its use for IBD treatment are currently sparse. We aimed to investigate the long‐term efficacy and safety of CT‐P13 therapy in a large, real‐life IBD cohort. Methods A total of 368 IBD patients (227 with Crohn's disease [CD] and 141 with ulcerative colitis [

ImmunologyImmunology and Microbiology
10
Article|27 citations·2016
Does Low Threshold Value Use Improve Proximal Neoplasia Detection by Fecal Immunochemical Test?
Nam Hee Kim, Hyo‐Joon Yang, Soo‐Kyung Park, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyu-Yong Choi, Yoon Suk Jung
SJR Q2Digestive Diseases and Sciences
OncologyMedicine
11
Article|27 citations·2018
Impact of clinically evident portal hypertension on clinical outcome of patients with hepatocellular carcinoma treated by transarterial chemoembolization
Nam Hee Kim, Taeheon Lee, Yong Kyun Cho, Byung Ik Kim, Hong Joo Kim
SJR Q1Journal of Gastroenterology and Hepatology

Abstract Background and Aim The aim of this study is to determine the impact of clinically evident portal hypertension (CEPH) on prognosis of hepatocellular carcinoma (HCC) patients with Child–Pugh A cirrhosis who underwent transarterial chemoembolization (TACE). Methods A retrospective data analysis was performed for a total of 388 treatment‐naïve HCC patients with Child–Pugh A cirrhosis who underwent TACE as first‐line treatment from January 2000 to June 2014. Cumulative occurrence rate of com

HepatologyMedicine
12
Article|26 citations·2020
Diagnostic Performance and Prognostic Relevance of FDG Positron Emission Tomography/Computed Tomography for Patients with Extrahepatic Cholangiocarcinoma
Nam Hee Kim, Sung Ryol Lee, Young Hwan Kim, Hong Joo Kim
SJR Q1Korean Journal of RadiologyOA

FDG PET-CT showed lower sensitivity for detecting primary tumor and regional lymph node involvement than MDCT and MRI. However, the SUV<sub>max</sub> of primary tumors and metastatic lesions derived from FDG PET-CT could have significant implications for predicting prognoses in extrahepatic cholangiocarcinoma patients.

SurgeryMedicine
13
Article|25 citations·2016
The fecal immunochemical test has high accuracy for detecting advanced colorectal neoplasia before age 50
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyu-Yong Choi, Yoon Suk Jung
SJR Q1Digestive and Liver Disease
OncologyMedicine
14
Article|25 citations·2014
Long-Term Clinical Outcomes of Korean Patient With Crohn's Disease Following Early Use of Infliximab
Nam Hee Kim, Yoon Suk Jung, Chang Mo Moon, Shin Yeong Lee, Eun Ran Kim, Young Ho Kim, Chang Kyun Lee, Suck Ho Lee, Jae Hak Kim, Kyu Chan Huh, Soon Man Yoon, Hyun Joo Song
SJR Q2Intestinal ResearchOA

The early use of IFX did not reduce CD-related surgery requirements in Korean patients with CD. These study results suggest that the early use of IFX may have little impact on the clinical outcome of CD in Korean patients in the setting of a conventional step-up algorithm.

GeneticsBiochemistry, Genetics and Molecular Biology
15
Article|23 citations·2016
Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyu-Yong Choi, Yoon Suk Jung
SJR Q3MedicineOA

We investigated the risk factors for adenoma occurrence at surveillance colonoscopy, especially focusing on patient characteristics, including metabolic factors.Surveillance colonoscopy intervals depend on baseline adenoma characteristics. However, patients' characteristics may also influence the occurrence of adenomas.Of 62,171 asymptomatic subjects who underwent colonoscopy for a health check-up between 2010 and 2011, 4869 subjects who underwent follow-up colonoscopy between 2012 and 2013 were

OncologyMedicine

Research Areas

OncologyEpidemiologyPulmonary and Respiratory MedicineSurgeryPhysiologyNutrition and Dietetics

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