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Pansik Jang

Seoul National University · Biochemistry, Genetics and Molecular Biology

About the Lab

Professor Pansik Jang's research lab specializes in biocatalysis and carbohydrate chemistry, focusing on the enzymatic and chemical modification of polysaccharides and lipids to enhance their solubility, stability, and functional properties. The lab develops innovative biotechnological approaches such as TEMPO-mediated oxidation of polysaccharides, lipase-catalyzed glycerolysis in microemulsion and reversed micellar systems, and the characterization of novel proteases from medicinal plants. These studies are applied to food science and nanotechnology, aiming to improve food quality, develop smart packaging, and enable sustainable bioprocesses. The lab also integrates advanced analytical techniques like HPLC and backscattering spectroscopy to monitor reaction kinetics and emulsion stability.

biocatalysispolysaccharide modificationlipase systemsnanomaterials in foodprotease characterization

Research Overview

Papers
239
Total Citations
5,248
Papers (5y)
51
Primary Field
Biochemistry, Genetics and Molecular Biology

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
51total
2022
2023
2024
2025
2026
Citations per year (5y)
332total
20222023202420252026

Selected Papers

15
1
Article|187 citations·1996
Oxidation of Primary Alcohol Groups of Naturally Occurring Polysaccharides with 2,2,6,6-Tetramethyl-1-Piperidine Oxoammonium Ion
Pahn‐Shick Chang, John F. Robyt
SJR Q3Journal of Carbohydrate Chemistry

ABSTRACT The primary alcohol groups of ten polysaccharides, with widely different structures and water solubilities, were oxidized to carboxyl groups using 2,2,6,6-tetramethyl-1-piperidine oxoammonium ion (TEMPO) at pH 10.8 and 0°C. The yield and selectivity for the primary alcohol group were high for all ten of the polysaccharides. The oxidation greatly increased the water-solubility of the polysaccharides. Water-insoluble polysaccharides such as amylose, cellulose, and chitin became water-solu

Plant ScienceAgricultural and Biological Sciences
2
Article|133 citations·2018
An Overview of Nanotechnology in Food Science: Preparative Methods, Practical Applications, and Safety
Hyunjong Yu, Jun‐Young Park, Chang Woo Kwon, Sung-Chul Hong, Kyung‐Min Park, Pahn‐Shick Chang
SJR Q2Journal of ChemistryOA

As the researches to utilize nanotechnology in food science are advanced, applications of nanotechnology in various fields of the food industry have increased. Nanotechnology can be applied to the food industry for production, processing, storage, and quality control of foods. Nanomaterials, unlike conventional microscale materials, having novel characteristics can improve sensory quality of foods by imparting novel texture, color, and appearance. Nanotechnology has been used to design nanosenso

Food ScienceAgricultural and Biological Sciences
3
Article|107 citations·2014
Dual-channel detection of Cu2+ and F− with a simple Schiff-based colorimetric and fluorescent sensor
Yu Jeong Na, Ye Won Choi, Jin Yeong Yun, Kyung‐Min Park, Pahn‐Shick Chang, Cheal Kim
SJR Q2Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
SpectroscopyChemistry
4
Article|75 citations·2023
Precise control of liposome size using characteristic time depends on solvent type and membrane properties
Sunghak Choi, Bongsu Kang, Eunhye Yang, Keesung Kim, Moon Kyu Kwak, Pahn‐Shick Chang, Ho‐Sup Jung
SJR Q1Scientific ReportsOA

Controlling the sizes of liposomes is critical in drug delivery systems because it directly influences their cellular uptake, transportation, and accumulation behavior. Although hydrodynamic focusing has frequently been employed when synthesizing nano-sized liposomes, little is known regarding how flow characteristics determine liposome formation. Here, various sizes of homogeneous liposomes (50-400 nm) were prepared according to flow rate ratios in two solvents, ethanol, and isopropyl alcohol (

BiomaterialsMaterials Science
5
Article|69 citations·1991
Continuous glycerolysis of olive oil by Chromobacterium viscosum lipase immobilized in liposome in reversed micelles
Pahn‐Shick Chang, Joon Shick Rhee, Jae‐Jin Kim
SJR Q2Biotechnology and Bioengineering

Chromobacterium viscosum lipase which has adsorbed on liposome and solubilized in microemulsion droplets of glycerol containing a little amount of water could catalyze the glycerolysis of olive oil. Studies on the continuous glycerolysis of olive oil by the immobilized enzyme was done at 37 degrees C in continuous stirred vessel bioreactor with polysulfone membrane. The effect of the flow rate of substrate (olive oil) in isooctane on the conversion and composition of the outlet was investigated

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
Article|66 citations·2014
Extraction characteristics of subcritical water depending on the number of hydroxyl group in flavonols
Chan-Ick Cheigh, Seo-Yeon Yoo, Min-Jung Ko, Pahn‐Shick Chang, Myong‐Soo Chung
SJR Q1Food Chemistry
Pathology and Forensic MedicineMedicine
7
Article|63 citations·2020
Microfluidic assembly of liposomes dual-loaded with catechin and curcumin for enhancing bioavailability
Sung-Chul Hong, Kyung‐Min Park, Chi Rac Hong, Jin‐Chul Kim, Seung‐Hoon Yang, Hyung‐Seok Yu, Hyun‐Dong Paik, Cheol‐Ho Pan, Pahn‐Shick Chang
SJR Q1Colloids and Surfaces A Physicochemical and Engineering Aspects
Molecular MedicineBiochemistry, Genetics and Molecular Biology
8
Article|54 citations·2014
Solvent-dependent chromogenic sensing for Cu2+ and fluorogenic sensing for Zn2+ and Al3+: a multifunctional chemosensor with dual-mode
Gyeong Jin Park, Dae Yul Park, Kyung‐Min Park, Youngmee Kim, Sung‐Jin Kim, Pahn‐Shick Chang, Cheal Kim
SJR Q3Tetrahedron
SpectroscopyChemistry
9
Article|47 citations·2018
Hydrophilic and lipophilic characteristics of non-fatty acid moieties: significant factors affecting antibacterial activity of lauric acid esters
Kyung‐Min Park, Seon Joo Lee, Hyunjong Yu, Jun‐Young Park, Ho‐Sup Jung, Keesung Kim, Chang Joo Lee, Pahn‐Shick Chang
SJR Q2Food Science and BiotechnologyOA
Inorganic ChemistryChemistry
10
Article|46 citations·1961
LIPID OXIDATION IN PRE-COOKED BEEF PRESERVED BY REFRIGERATION, FREEZING, AND IRRADIATION.
Pahn‐Shick Chang, MARGARET T. YOUNATHAN, Betty M. Watts
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)
Nutrition and DieteticsNursing
11
Article|41 citations·2016
Erythorbyl laurate as a potential food additive with multi-functionalities: Interfacial characteristics and antioxidant activity
Kyung‐Min Park, Min-Joo Lee, Su-Kyung Jo, Seung Jun Choi, JaeHwan Lee, Pahn‐Shick Chang
SJR Q1Food Chemistry
Organic ChemistryChemistry
12
Article|40 citations·2011
Lipase-catalysed synthesis of erythorbyl laurate in acetonitrile
Kyung‐Min Park, Da Eun Lee, Ho Jin Sung, JaeHwan Lee, Pahn‐Shick Chang
SJR Q1Food Chemistry
Molecular BiologyBiochemistry, Genetics and Molecular Biology
13
Article|40 citations·2014
A New Method for Determining the Emulsion Stability Index by Backscattering Light Detection
Seung Jun Choi, Jong Won Won, Kyung‐Min Park, Pahn‐Shick Chang
SJR Q2Journal of Food Process Engineering

Abstract In the present study, the Δbackscattering (Δ BS ) method was developed as a simple and sensitive tool for determining the emulsion stability index ( ESI ) by backscattering light detection. The backscattering light detection method uses emulsion‐scanning technology to monitor physical behavior in an emulsion as a function of storage time. Emulsions were prepared by the homogenization (8,000 rpm for 2 min at 25C) of distilled water and perilla oil containing Tween 60, and the sample was

Food ScienceAgricultural and Biological Sciences
14
Article|39 citations·2018
Transcriptomic analysis of Staphylococcus aureus under the stress condition of antibacterial erythorbyl laurate by RNA sequencing
Jun‐Young Park, Su-Kyung Jo, Kyung‐Min Park, Hyunjong Yu, Jaewoo Bai, Sangryeol Ryu, Pahn‐Shick Chang
SJR Q1Food Control
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Article|35 citations·1990
Characteristics of Lipase-Catalyzed Glycerolysis of Triglyceride in AOT-Isooctane Reversed Micelles
Pahn‐Shick Chang, Joon Shick Rhee
Biocatalysis

Chromobacterium viscosum lipase, solubilized in microemulsion droplets of glycerol containing small amounts of water and stabilized by a surfactant, could catalyze the glycerolysis of triolein. Kinetic analysis of the lipase-catalyzed reaction was possible in the reversed micellar system. Among surfactants and organic solvents tested, bis(2-ethylhexyl)sodiumsulfosuccinate (AOT) and isooctane were respectively most effective, for the glycerolysis of triolein in reversed micelles. Temperature effe

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

Molecular BiologyFood ScienceOrganic ChemistryBiotechnologyBiomaterialsPathology and Forensic Medicine

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