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Seokhwan Lee

Kyung Hee University · Medicine

About the Lab

Professor Seokhwan Lee's research lab specializes in minimally invasive and oncologic colorectal surgery, with a focus on advanced surgical techniques for colorectal cancer, including laparoscopic and robotic surgery in complex anatomical variants such as situs inversus totalis. The lab is actively involved in investigating organ-preserving strategies, such as total neoadjuvant therapy (TNT), and the application of novel biomarkers like SDC2 methylation in stool DNA for early detection of colorectal cancer. The team emphasizes multidisciplinary approaches to improve patient outcomes, combining surgical innovation with precision diagnostics and enhanced recovery protocols.

colorectal cancerminimally invasive surgeryorgan preservationearly detection biomarkerstotal neoadjuvant therapy

Research Overview

Papers
181
Total Citations
3,221
Papers (5y)
24
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
24total
2021
2022
2023
2024
2025
Citations per year (5y)
459total
20212022202320242025

Selected Papers

15
1
Article|42 citations·2012
Surgical Management of Enterocutaneous Fistula
Suk-Hwan Lee
SJR Q1Korean Journal of RadiologyOA

Enterocutaneous (EC) fistula is an abnormal connection between the gastrointestinal (GI) tract and skin. The majority of EC fistulas result from surgery. About one third of fistulas close spontaneously with medical treatment and radiologic interventions. Surgical treatment should be reserved for use after sufficient time has passed from the previous laparotomy to allow lysis of the fibrous adhesion using full nutritional and medical treatment and until a complete understanding of the anatomy of

Pulmonary and Respiratory MedicineMedicine
2
Article|28 citations·2017
Single-Port Laparoscopic Surgery Can Be Performed Safely and Appropriately for Colon Cancer: Short-Term Results of a Pilot Randomized Controlled Trial
Byung Mo Kang, Sun Jin Park, Kil Yeon Lee, Suk-Hwan Lee
SJR Q2Journal of Laparoendoscopic & Advanced Surgical Techniques

SPLS for colon cancer is feasible and can be performed by following oncologic principles. However, surgeons should be aware of the potential for unexpected adjacent organ injury ( ClinicalTrial.gov identifier: NCT01203969).

SurgeryMedicine
3
Article|25 citations·2018
Single-port laparoscopic surgery in uncomplicated acute appendicitis: a randomized controlled trial
Byung Mo Kang, Sung Il Choi, Bum‐Soo Kim, Suk-Hwan Lee
SJR Q1Surgical Endoscopy
SurgeryMedicine
4
Article|23 citations·2021
Colorectal cancer screening using a stool DNA-based SDC2 methylation test: a multicenter, prospective trial
Chang Woo Kim, Hyunjin Kim, Hyoung Rae Kim, Bong‐Hyeon Kye, Hyung Jin Kim, Byung Soh Min, Tae Jeong Oh, Sungwhan An, Suk-Hwan Lee
SJR Q2BMC GastroenterologyOA

Abstract Background Prevention and early detection of colorectal cancer (CRC) is a global priority, with many countries conducting population-based CRC screening programs. Although colonoscopy is the most accurate diagnostic method for early CRC detection, adherence remains low because of its invasiveness and the need for extensive bowel preparation. Non-invasive fecal occult blood tests or fecal immunochemical tests are available; however, their sensitivity is relatively low. Syndecan-2 ( SDC2

OncologyMedicine
5
Article|16 citations·2020
Quality of life and patient satisfaction after single- and multiport laparoscopic surgery in colon cancer: a multicentre randomised controlled trial (SIMPLE Trial)
Byung Mo Kang, Yoon Suk Lee, Ji Hoon Kim, Hyung Jin Kim, Sang Chul Lee, Chang Woo Kim, Sang Woo Lim, Jun Gi Kim, Suk-Hwan Lee
SJR Q1Surgical Endoscopy
SurgeryMedicine
6
Article|16 citations·2011
Laparoscopic Abdominoperineal Resection for Rectal Cancer in a Patient With Situs Inversus Totalis
Sung Il Choi, Sun Jin Park, Byung Mo Kang, Kil Yeon Lee, Haeng Chul Lee, Suk-Hwan Lee
SJR Q2Surgical Laparoscopy Endoscopy & Percutaneous Techniques

Situs inversus totalis (SIT) is a very rare condition. Laparoscopic surgery in a patient with SIT is difficult because the surgeon's dexterity is compromised during the procedure, and the patient's anatomy is the mirror image of normal. We present a SIT patient who underwent laparoscopic abdominoperineal resection for rectal cancer. The detailed operative procedures and trocar placement considerations are described.

SurgeryMedicine
7
Review|12 citations·2023
Total neoadjuvant therapy for rectal cancer: evidence and challenge
Suk-Hwan Lee
SJR Q2Annals of ColoproctologyOA

Recent advances in the management of rectal cancer have dramatically changed the clinical practice of colorectal surgeons because the main focus of rectal cancer treatment has changed from sphincter-saving to an organ-preserving strategies. Modifying the delivery of systemic chemotherapy to improve patients' survival is another progress in colorectal cancer management, known as total neoadjuvant therapy (TNT). TNT is a new strategy used by colorectal surgeons to improve the quality of life and s

OncologyMedicine
8
Article|9 citations·2010
Endo-Satinsky Clamp for Rectal Transection During Laparoscopic Total Mesorectal Excision
Sun Jin Park, Sung Il Choi, Suk-Hwan Lee, Kil Yeon Lee
SJR Q2Diseases of the Colon & Rectum

The endo-Satinsky clamp is a useful device for rectal transection and irrigation. The use of this device makes it easier to place an endostapler just distal to the clamp and to transect the rectum in a more appropriate position.

OncologyMedicine
9
Article|7 citations·2024
A Stool DNA-Based SDC2 Methylation Test for the Early Detection of Colorectal Cancer in an Asymptomatic, High-Risk Population: A Multicenter Prospective Randomized Trial
Chang Woo Kim, Hyunjin Kim, Hyoung Rae Kim, Daeyeon David Won, Woo Jung Nam, Byung Soh Min, Tae Jeong Oh, Sungwhan An, Suk-Hwan Lee
SJR Q1The American Journal of Gastroenterology

INTRODUCTION: Noninvasive stool DNA-based methylation testing has emerged as an effective strategy for the early colorectal cancer (CRC) detection. Syndecan-2 ( SDC2 ) methylation frequently occurs in all stages of CRC; therefore, the aim of this study was to evaluate the clinical performance of a stool DNA-based SDC2 methylation test for detecting CRC in asymptomatic or high-risk CRC populations. METHODS: This multicenter prospective study was conducted to determine the clinical performance of

OncologyMedicine
10
editorial|6 citations·2019
Changing Trend of Rectal Prolapse Surgery in the Era of the Minimally Invasive Surgery
Suk-Hwan Lee
Daehan nae'si'gyeong bog'gang'gyeong oe'gwa haghoeji/Journal of minimally invasive surgeryOA

With the life span of the general population increased, rectal prolapse in elderly patients became a major concern in terms of the decision of the treatment modalities and quality of life of patients. Most elderly patients with rectal prolapse in the past received a perineal approach with the fear of general anesthetic complications rather than the abdominal approach. However, improvement in perioperative care in anesthesiology and minimally invasive surgery, the trend of surgical management of

RheumatologyMedicine
11
Article|5 citations·2025
Short-term outcomes of single-port robotic surgery versus single-port laparoscopic surgery for colon cancer: a multicenter matched-cohort analysis
Gyoung Tae Noh, Young Il Kim, Seung Ho Song, Hye Jin Kim, Songsoo Yang, Yong Sik Yoon, Ji Hoon Kim, Hyung Jin Kim, Byung Mo Kang, Chang Woo Kim, Suk-Hwan Lee, Jun Gi Kim
SJR Q1Surgical Endoscopy
SurgeryMedicine
12
Article|5 citations·2019
How to Achieve a Higher Pathologic Complete Response in Patients With Locally Advanced Rectal Cancer Who Receive Preoperative Chemoradiation Therapy
Suk-Hwan Lee
SJR Q2Annals of ColoproctologyOA

The current standard of care for treating patients with locally advanced rectal cancer includes preoperative chemoradiation therapy (PCRT) followed by a total mesorectal excision and postoperative adjuvant chemotherapy. A subset of these patients has achieved a pathologic complete response (pCR) and they have shown improved disease-free and overall survival compared to non-pCR patients. Thus, many efforts have been made to achieve a higher pCR through PCRT. In this review, results from various o

OncologyMedicine
13
Review|3 citations·2021
Does surgical smoke matter?
Suk-Hwan Lee
Daehan nae'si'gyeong bog'gang'gyeong oe'gwa haghoeji/Journal of minimally invasive surgeryOA

The coronavirus disease 2019 (COVID-19) pandemic has dramatically changed our daily lives and medical practices since it was first reported in December 2019 in Wuhan, China. Unlike the usual transmission patterns of other viral diseases, the asymptomatic or presymptomatic transmission of COVID-19 has caused difficulties in disease control around the globe. Surgical smoke or fumes may carry viruses. However, there is no evidence that the severe acute respiratory syndrome coronavirus 2, which caus

OncologyMedicine
14
Article|3 citations·2005
Current Status of Stoma Researches in Korea
Suk-Hwan Lee, Eung Bum Park
Journal of The Korean Society of Coloproctology

Stoma operations are one of the most frequently performed operation by the colorectal surgeons. And the consequences of the stoma operation of the patients are well known. However, most colorectal surgeons who performed stoma operation were not aware of the problems that are part of the rehabilitation of the ostomates. In order to elucidate the current status of the stoma studies in Korea, literature reviews were performed by using the Korean medical literature database. Most of the Korean liter

SurgeryMedicine
15
Article|1 citations·2006
[TNM staging, molecular staging and prognostic factors of rectal cancer].
Suk-Hwan Lee
PubMed

Pathologic evaluation of the resected specimen is a critical component when managing the patients with rectal cancer, from initial diagnosis through definitive treatment. The best estimation of prognosis in rectal cancer is related to the anatomic extent of disease determined by pathology. Although a large number of staging system has been developed for rectal cancer over the years, use of TNM staging system of the AJCC (American Joint Committee on Cancer) and the UICC (International Union Again

OncologyMedicine

Research Areas

SurgeryOncologyPulmonary and Respiratory MedicinePathology and Forensic MedicineHepatologyGastroenterology

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