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Seung Yong Song

Yonsei University · Medicine

About the Lab

Professor Seung Yong Song's research lab specializes in regenerative medicine and plastic and reconstructive surgery, with a strong focus on adipose-derived stem cells (ASCs) and their therapeutic potential in tissue repair and regeneration. The lab investigates both the paracrine signaling and differentiation capacity of ASCs, exploring pharmacological modulators like megestrol acetate to enhance their proliferation and regenerative functions. Additionally, the lab conducts clinical and translational research in craniofacial reconstruction, including innovative fixation techniques for frontal sinus fractures using absorbable materials, and contributes to ophthalmic infection research, particularly in rare bacterial endophthalmitis cases.

adipose-derived stem cellsregenerative medicinecraniofacial reconstructionparacrine signalingtissue engineering

Research Overview

Papers
181
Total Citations
2,804
Papers (5y)
36
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
36total
2022
2023
2024
2025
2026
Citations per year (5y)
246total
20222023202420252026

Selected Papers

15
1
Review|103 citations·2010
The pivotal role of VEGF in adipose-derived-stem-cell-mediated regeneration
Seung Yong Song, Hyung‐Min Chung, Jong-Hyuk Sung
SJR Q1Expert Opinion on Biological Therapy

Most studies of stem cell regeneration have focused on differentiation of ASCs and their building block function; however, the paracrine effects of ASCs should also be the focus of attention.

GeneticsMedicine
2
Article|85 citations·2018
Nipple-areolar complex ischemia and necrosis in nipple-sparing mastectomy
Sung Jae Ahn, Tae Yong Woo, Dong Won Lee, Dae Hyun Lew, Seung Yong Song
SJR Q1European Journal of Surgical OncologyOA
SurgeryMedicine
3
Article|75 citations·2021
Human Adipose Mesenchymal Stem Cell-Derived Exosomes: A Key Player in Wound Healing
June Seok Heo, Sinyoung Kim, Chae Eun Yang, Youjeong Choi, Seung Yong Song, Hyun Ok Kim
SJR Q1Tissue Engineering and Regenerative MedicineOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
Article|58 citations·2009
Superior lipolytic effect of the 1,444 nm Nd:YAG laser: Comparison with the 1,064 nm Nd:YAG laser
Kwan Chul Tark, Ji Eun Jung, Seung Yong Song
SJR Q1Lasers in Surgery and MedicineOA

BACKGROUND AND OBJECTIVES: Recently developed laser lipolysis systems have been disappointing because they require more time to remove the same amount of fat than other liposuction methods. A new Nd:YAG laser has been introduced that uses the 1,444 nm wavelength, better absorbed by fat. STUDY DESIGN/MATERIALS AND METHODS: This study consisted of two protocols. The first protocol was an in vivo minipig model. Four 10x10 cm(2) areas were treated on the back of the first minipig. Using the same tot

SurgeryMedicine
5
Article|49 citations·2010
Determination of adipose-derived stem cell application on photo-aged fibroblasts, based on paracrine function
Seung Yong Song, Ji Eun Jung, Yeo Reum Jeon, Kwan Chul Tark, Dae Hyun Lew
SJR Q1CytotherapyOA
DermatologyMedicine
6
Article|29 citations·2018
Evaluation of the Relationship Between Flap Tension and Tissue Perfusion in Implant-Based Breast Reconstruction Using Laser-Assisted Indocyanine Green Angiography
Chae Eun Yang, Soon Won Chung, Dong Won Lee, Dae Hyun Lew, Seung Yong Song
SJR Q1Annals of Surgical OncologyOA
SurgeryMedicine
7
Article|28 citations·2007
An Epidemic of Chronic Pseudophakic Endophthalmitis Due toOchrobactrum anthropi: Clinical Findings and Managements of Nine Consecutive Cases
Seung Yong Song, Jae Kyoun Ahn, Gwang Hoon Lee, Yeoung Geol Park
SJR Q2Ocular Immunology and InflammationOA

PURPOSE: To report an epidemic of O. anthropi pseudophakic endophthalmitis. METHODS: The medical records of nine patients with culture-proven O. anthropi endophthalmitis were reviewed. RESULTS: The presenting features were compatible to chronic endophthalmitis. Two patients showed coinfections with P. acnes. Antibiotics sensitivity test revealed susceptibility to quinolones. Pars plana vitrectomy (PPV) with partial capsulectomy (PC) cured infections in seven patients without coinfection of P. ac

EndocrinologyBiochemistry, Genetics and Molecular Biology
8
Article|25 citations·2009
Volume and distances of the maxillary sinus in craniofacial deformities with midfacial hypoplasia
Seung Yong Song, Jong Won Hong, Tai Suk Roh, Yong Oock Kim, Deok Won Kim, Beyoung Yun Park
SJR Q1OtolaryngologyOA

OBJECTIVE: Craniofacial deformities (CFDs) frequently accompany midfacial hypoplasia. The authors evaluated characteristics of maxillary sinuses that had CFDs with variable degrees of midfacial hypoplasia. STUDY DESIGN: Cross-sectional survey with chart review. SETTING: Department of Plastic and Reconstructive Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea. SUBJECTS AND METHODS: We investigated 40 patients with CFDs having midfacial hypoplasia. Study

GeneticsBiochemistry, Genetics and Molecular Biology
9
Article|21 citations·1999
New soluble light-emitting diode polymer containing oxadiazole unit
Seung Yong Song, M. S. Jang, H. K. Shim, Inyong Song, W.-H. Kim
SJR Q1Synthetic Metals
Electrical and Electronic EngineeringEngineering
10
Article|14 citations·2015
Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Jong-Hyuk Sung, H. An, Jin-Hyun Jeong, Soyoung Shin, Seung Yong Song
SJR Q1Stem Cells Translational MedicineOA

UNLABELLED: : Because adipose-derived stem cells (ASCs) are usually expanded to acquire large numbers of cells for therapeutic applications, it is important to increase the production yield and regenerative potential during expansion. Therefore, a tremendous need exists for alternative ASC stimuli during cultivation to increase the proliferation and adipogenic differentiation of ASCs. The present study primarily investigated the involvement of megestrol acetate (MA), a progesterone analog, in th

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
Article|13 citations·2012
Treatment of Frontal Sinus Fracture Using Bioabsorbable Mesh Plates
Chung Hun Kim, Dae‐Hee Kim, Da Han Kim, Seung Yong Song
SJR Q2Journal of Craniofacial Surgery

Accurate reduction and stable fixation are important in the treatment of frontal sinus fracture. Usually, metal plates and screws were used because of easy handling and delicate fixation. However, palpability and possibility for secondary operation for plate removal were shortcomings. For improving these problems, we used absorbable mesh plate for fixation of reduced frontal bones.In this study, 14 patients with frontal sinus fracture were treated by open reduction and rigid fixation using absor

SurgeryMedicine
12
Article|10 citations·2020
Hypofractionated Radiotherapy With Volumetric Modulated Arc Therapy Decreases Postoperative Complications in Prosthetic Breast Reconstructions: A Clinicopathologic Study
Seung Yong Song, Jee Suk Chang, Kenneth L. Fan, Mi Jung Kim, Hsien Pin Chang, Dae Hyun Lew, Tai Suk Roh, Hyun Roh, Yong Bae Kim, Dong Won Lee
SJR Q2Frontiers in OncologyOA

We demonstrated that hypofractionated RT with VMAT served to reduce radiation-related morbidities in prosthetic reconstruction from a clinicopathologic perspective, compared to conventional RT. It may offer a practical strategy to mitigate radiation-related complications in clinical settings.

SurgeryMedicine
13
Article|10 citations·2009
Gossypiboma After Mandibular Contouring Surgery
Seung Yong Song, Jong Won Hong, Won Min Yoo, Kwan Chul Tark
SJR Q2Journal of Craniofacial SurgeryOA

Gossypiboma must be considered when fever, unilateral swelling, tenderness, or unhealed oral wound is sustained despite an antibiotics therapy and a drainage procedure after a mandible angle surgery. In that case, a computed tomographic scan can be recommended as an effective method for detection of gossypiboma.

HematologyMedicine
14
Article|7 citations·2025
Injectable Human Acellular Adipose Matrix with Crosslinked Hyaluronic Acid and Carboxymethyl Cellulose Gels for Soft Tissue Augmentation
Si Youn Kim, Jung Ki Lee, Soon Won Jung, Kee‐Won Lee, Seung Yong Song
SJR Q1Tissue Engineering and Regenerative MedicineOA
SurgeryMedicine
15
Article|6 citations·2002
SPONTANEOUS REGRESSION OF A SOLITARY ASTROCYTOMA OF THE OPTIC DISK
Seung Yong Song, Man-Seong Seo
SJR Q1Retina

From the Department of Ophthalmology, Chonnam National University Medical School and Hospital, Chonnam National Research Institute for Medical Sciences, Kwangju, Korea. Reprint requests: Man-Seong Seo, MD, PhD, Department of Ophthalmology, Chonnam University Hospital, 8 Hakdong Tongku, Kwangju 501-757, Korea; e-mail: [email protected]

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

SurgeryElectrical and Electronic EngineeringGeneticsDermatologyMolecular BiologyUrology

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