Si‐Ho Kim
Sungkyunkwan University · Medicine
About the Lab
Professor Si-Ho Kim's research lab focuses on infectious diseases, antimicrobial resistance, and clinical outcomes in hospitalized patients, with a particular emphasis on bloodstream infections, antibiotic stewardship, and vaccine safety. The lab investigates the epidemiology and pathogenesis of serious bacterial infections, including vancomycin-resistant Enterococcus and Staphylococcus aureus bacteremia, while evaluating the impact of antimicrobial use and host factors on patient mortality. Research also extends to vaccine-associated adverse events and the role of corticosteroids in severe infectious complications such as CAPA (COVID-19-associated pulmonary aspergillosis). The lab integrates clinical microbiology with epidemiological and statistical approaches to improve patient outcomes through evidence-based infection management strategies.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Coronavirus disease 2019 vaccinations for healthcare workers (HCWs) have begun in South Korea. To investigate adverse events (AEs) of the first dose of each vaccine, any symptom was collected daily for seven days after vaccination in a tertiary hospital. We found that 1,301 of 1,403 ChAdOx1 nCoV-19 recipients and 38 of 80 BNT162b2 recipients reported AEs respectively (90.9% vs. 52.5%): injection-site pain (77.7% vs. 51.2%), myalgia (60.5% vs. 11.2%), fatigue (50.7% vs. 7.5%), headache (47.4% vs.
BACKGROUND: The epidemiology of bloodstream infection (BSI) is well-established; however, little is known about the contribution of different pathogens to mortality. To understand true burden of BSI, pathogens contributing to mortality were investigated and compared according to where the BSI was acquired. METHODS: Data from deceased patients in two teaching hospitals in the Republic of Korea were collected. BSI contributing mortality was defined as BSI within 2-weeks before death. Cases were gr
Our study showed that the dose of corticosteroid use might be a risk factor for CAPA development and the possibility of CAPA contributing to adverse outcomes in critically ill COVID-19 patients.
In patients with persistent SAB, PBS at treatment day 4 was associated with 30-day in-hospital mortality rather than defervescence and bacteremia duration. The results of this study could help determine early intensified treatment strategies in persistent SAB patients.
BACKGROUND: Sequence type (ST) 17 vancomycin-resistant Enterococcus faecium (VREF) is frequently isolated in nosocomial settings. The aim of this study was to identify whether ST17 contributes to subsequent bacteremia more often than other STs among hospitalized patients carrying VREF. METHODS: A retrospective cohort study was conducted in patients carrying ST17 VREF and those with non-ST17 VREF. Rectal screening according to hospital policy was used to identify patients with VREF. Subsequent VR
A comprehensive ASP decreased the use of APBL and was associated with improved patient outcomes.
Research Areas
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