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Sin-Ho Kuk

Sungkyunkwan University · Medicine

About the Lab

Professor Sin-Ho Kuk's research lab specializes in diagnostic breast imaging, with a focus on advancing ultrasound elastography, contrast-enhanced imaging techniques such as CEDM and CEMRI, and image-guided interventions in breast cancer. The lab investigates innovative methods for tumor localization using surgical clips and marker clips, particularly in the context of neoadjuvant chemotherapy and sentinel lymph node biopsy. Their work emphasizes improving diagnostic accuracy, treatment planning, and surgical outcomes through advanced medical imaging technologies.

ultrasound elastographycontrast-enhanced digital mammographyimage-guided localizationbreast cancer imagingsurgical clip

Research Overview

Papers
67
Total Citations
677
Papers (5y)
12
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
12total
2020
2022
2023
2024
2025
Citations per year (5y)
80total
20202022202320242025

Selected Papers

15
1
Review|103 citations·2013
Practice guideline for the performance of breast ultrasound elastography
Su Hyun Lee, Jung Min Chang, Nariya Cho, Hye Ryoung Koo, Ann Yi, Seung Ja Kim, Ji Hyun Youk, Eun Ju Son, Seon Hyeong Choi, Shin Ho Kook, Jin Chung, Eun Suk
SJR Q1ULTRASONOGRAPHYOA

Ultrasound (US) elastography is a valuable imaging technique for tissue characterization. Two main types of elastography, strain and shear-wave, are commonly used to image breast tissue. The use of elastography is expected to increase, particularly with the increased use of US for breast screening. Recently, the US elastographic features of breast masses have been incorporated into the 2nd edition of the Breast Imaging Reporting and Data System (BI-RADS) US lexicon as associated findings. This r

Radiology, Nuclear Medicine and ImagingMedicine
2
Article|97 citations·2000
Metastatic tumors to the breast: mammographic and ultrasonographic findings.
Sang Lee, J M Park, Shin Ho Kook, Boo‐Kyung Han, W K Moon
SJR Q2Journal of Ultrasound in Medicine

We evaluated the mammographic (n = 16) and ultrasonographic (n = 15) findings of 18 patients with metastatic breast carcinoma. Fifteen patients showed multiple or diffuse lesions and three patients showed single lesions. Ten patients (55.6%) had bilateral lesions. Mammography revealed high density (15 cases, 93.8%), round to oval (11 cases, 68.8%) lesions with poorly defined or obscured margins (12 cases, 75.0%). No associated calcification was found in any lesion. Ultrasonographically, poorly d

Reproductive MedicineMedicine
3
Article|64 citations·2018
Diagnostic Value of Contrast-Enhanced Digital Mammography versus Contrast-Enhanced Magnetic Resonance Imaging for the Preoperative Evaluation of Breast Cancer
Eun Young Kim, Inyoung Youn, Kwan Ho Lee, Ji‐Sup Yun, Yong Lai Park, Chan Heun Park, Juhee Moon, Seon Hyeong Choi, Yoon Jung Choi, Soo‐Youn Ham, Shin Ho Kook
SJR Q2Journal of Breast CancerOA

CEDM demonstrated a diagnostic performance comparable with CEMRI in depicting index cancers, secondary cancers, and occult cancer in the contralateral breast. CEDM demonstrated similar changes in surgical management compared with CEMRI.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
4
Article|41 citations·1998
Imaging of tuberculous disease involving breast
K.K. Oh, J. H. Kim, Shin Ho Kook
SJR Q1European Radiology
Radiology, Nuclear Medicine and ImagingMedicine
5
Article|41 citations·2017
Feasibility of Preoperative Axillary Lymph Node Marking with a Clip in Breast Cancer Patients Before Neoadjuvant Chemotherapy: A Preliminary Study
Eun Young Kim, W. Byon, Kwan Ho Lee, Ji‐Sup Yun, Yong Lai Park, Chan Heun Park, In Young Youn, Seon Hyeong Choi, Yoon Jung Choi, Shin Ho Kook, Sung‐Im Do
SJR Q1World Journal of Surgery

BACKGROUND: The aim of this study was to determine the feasibility of image-guided marker-clip placement in axillary lymph nodes (ALNs) for breast cancer upon initial presentation and to assess the reliability of this method with sentinel lymph node biopsy (SLNB) for axillary restaging after neoadjuvant chemotherapy (NAC). METHODS: Between June 2015 and August 2016, a marker clip was placed at a clinically positive ALN under ultrasonography (US) guidance before initiation of NAC in 20 patients.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|38 citations·2015
Ultrasonography-Guided Surgical Clip Placement for Tumor Localization in Patients Undergoing Neoadjuvant Chemotherapy for Breast Cancer
Inyoung Youn, Seon Hyeong Choi, Shin Ho Kook, Yoon Jung Choi, Chan Heun Park, Yong Lai Park, Dong Hoon Kim
SJR Q2Journal of Breast CancerOA

Surgical clips may replace commercial tissue markers for tumor localization in breast cancer patients undergoing NAC without migration. Surgical clips are well tolerated and safe for the patient, easily visualized on imaging, do not interfere with treatment response, and are cost-effective.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
7
Article|35 citations·2015
Usefulness of the oblique coronal plane in ankle MRI of the calcaneofibular ligament
H.J. Park, S.Y. Lee, N.H. Park, E. Kim, E C Chung, Shin Ho Kook, Joon Woo Lee
SJR Q2Clinical Radiology
Orthopedics and Sports MedicineMedicine
8
Article|34 citations·2019
Contrast enhanced digital mammography versus magnetic resonance imaging for accurate measurement of the size of breast cancer
Inyoung Youn, Seon-Hyeong Choi, Yoon Jung Choi, Ju Hee Moon, Hee Jin Park, Soo‐Youn Ham, Chan Heun Park, Eun Young Kim, Shin Ho Kook
SJR Q1British Journal of RadiologyOA

To compare the accuracy of contrast-enhanced digital mammography (CEDM) and MRI, including maximal intensity projection (MIP) images, for measuring the tumour size of breast cancer. We included 52 females (mean age, 50.9 years) with surgery due to breast cancer, and measured maximum diameter of main mass on mediolateral oblique (MLO) and craniocaudal (CC) views of mammography and CEDM; sagittal, axial MIP images, and early dynamic contrast-enhanced MRI (CEMRI) before surgery. Bland–Altman plot,

Pulmonary and Respiratory MedicineMedicine
9
Article|29 citations·2006
Schwannoma of the breast showing massive exophytic growth: A case report
Eunkyung Lee, Shin Ho Kook, Hyon‐Joo Kwag, Y.L. Park, Won Gil Bae
SJR Q1The Breast
NeurologyMedicine
10
Article|28 citations·2020
Preoperative evaluation of mammographic microcalcifications after neoadjuvant chemotherapy for breast cancer
Eung Yeop Kim, Sung‐Im Do, Jong-Min Yun, Y.L. Park, C.H. Park, Juhee Moon, In Young Youn, Young‐Gwan Choi, Soo‐Youn Ham, Shin Ho Kook
SJR Q2Clinical Radiology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
11
Article|27 citations·2011
Ultrasound and Clinicopathological Characteristics of Triple Receptor-Negative Breast Cancers
Yoon Jung Choi, Min Hyun Seong, Seon Hyeong Choi, Shin Ho Kook, Hyon Joo Kwag, Yong Lai Park, Chan Heun Park
SJR Q2Journal of Breast CancerOA

Tumor characteristics were different between TRN and non-TRN breast cancers, although US cannot differentiate the subtype of breast cancers TRN cancer tend to show somewhat different US morphology.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
12
Article|24 citations·2024
Screening mammography performance according to breast density: a comparison between radiologists versus standalone intelligence detection
Mi-ri Kwon, Yoosoo Chang, Soo‐Youn Ham, Yoosun Cho, Eun Young Kim, Jeonggyu Kang, Eun Kyung Park, Ki Hwan Kim, Minjeong Kim, Tae Soo Kim, Hyeonsoo Lee, Ria Kwon
SJR Q1Breast Cancer ResearchOA

BACKGROUND: Artificial intelligence (AI) algorithms for the independent assessment of screening mammograms have not been well established in a large screening cohort of Asian women. We compared the performance of screening digital mammography considering breast density, between radiologists and AI standalone detection among Korean women. METHODS: We retrospectively included 89,855 Korean women who underwent their initial screening digital mammography from 2009 to 2020. Breast cancer within 12 mo

Artificial IntelligenceComputer Science
13
Article|22 citations·2016
Mammographic Breast Density Evaluation in Korean Women Using Fully Automated Volumetric Assessment
윤인영, 최선형, 국신호, 최윤정
Journal of Korean Medical Science

The purpose was to present mean breast density of Korean women according to age using fully automated volumetric assessment. This study included 5,967 screening normal or benign mammograms (mean age, 46.2 ± 9.7; range, 30-89 years), from cancer-screening program. We evaluated mean fibroglandular tissue volume, breast tissue volume, volumetric breast density (VBD), and the results were 53.7 ± 30.8 cm3, 383.8 ± 205.2 cm3, and 15.8% ± 7.3%. The frequency of dense breasts and mean VBD by age group w

14
Article|17 citations·2011
Ultrasound and Clinicopathological Characteristics of Triple Receptor-Negative Breast Cancers
최윤정, 성민현, 최선형, 국신호, 곽현주, 박용래, 박찬흔
Journal of Breast Cancer

Purpose: Triple receptor-negative (TRN) breast cancer is associated with high risk of recurrence and poor prognosis. The pre- sent study assessed the clinicopathologic characteristics and ultrasound (US) features of TRN breast cancers. Methods: Pathol- ogical and biological data were reviewed for 558 breast cancer patients treated at Kangbuk Samsung Hospital, between January 2003 and December 2009. The patients were separated into TRN breast cancer and non-TRN breast cancer groups, based on the

15
Article|11 citations·2022
Performance analysis of screening mammography in Asian women under 40 years
Mi-ri Kwon, Yoosoo Chang, Boyoung Park, Seungho Ryu, Shin Ho Kook
SJR Q1Breast Cancer
OncologyMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingSurgeryCancer ResearchPulmonary and Respiratory MedicineReproductive MedicineNeurology

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