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So Hee Lee

Seoul National University · Medicine

About the Lab

Professor So Hee Lee's research lab focuses on translational biomedical research with a strong emphasis on respiratory diseases, neurodegenerative disorders, and medical imaging. The lab investigates the interplay between immune regulation, gut microbiota, and systemic diseases such as asthma and Alzheimer’s disease, while also developing advanced MRI phantoms for validating quantitative susceptibility mapping in neuroimaging. Their work bridges clinical phenotyping, molecular mechanisms, and diagnostic technology innovation.

asthmaAlzheimer’s diseasegut microbiotaMRI phantomsusceptibility imaging

Research Overview

Papers
52
Total Citations
630
Papers (5y)
11
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
11total
2020
2021
2022
2023
2025
Citations per year (5y)
73total
20202021202220232025

Selected Papers

15
1
Article|140 citations·2008
Epidemiologic and clinical features of anaphylaxis in Korea
Min‐Suk Yang, So-Hee Lee, Tae‐Wan Kim, Jae‐Woo Kwon, Sang Min Lee, Sae‐Hoon Kim, Hyouk-Soo Kwon, Changhan Park, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung‐Up Min
SJR Q1Annals of Allergy Asthma & Immunology
Immunology and AllergyMedicine
2
Article|55 citations·2008
Correlation between the Korean Version of Asthma Control Test and Health-Related Quality of Life in Adult Asthmatics
Hyouk‐Soo Kwon, So-Hee Lee, Min‐Suk Yang, Sang Min Lee, Sae‐Hoon Kim, Deok-In Kim, Seong-Wook Sohn, Chang-Han Park, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung-Up Min
SJR Q2Journal of Korean Medical ScienceOA

The Asthma Control Test (ACT) is a patient-completed questionnaire developed to assess asthma control. Health-related quality of life (HRQL) in asthmatics has shown relatively low correlations with parameters of asthma control and the relationship between the ACT and HRQL in asthmatics is yet unclear. Because revalidations of translated versions of questionnaires are critical for its utilization, we first sought to validate the Korean version of ACT and then to evaluate the relationship between

PhysiologyMedicine
3
Article|48 citations·2010
Outcomes of premedication for non-ionic radio-contrast media hypersensitivity reactions in Korea
Sae‐Hoon Kim, So-Hee Lee, Sang Min Lee, Hye‐Ryun Kang, Heung‐Woo Park, Sun-Sin Kim, Sang‐Heon Cho, Kyung-Up Min, You-Young Kim, Yoon‐Seok Chang
SJR Q1European Journal of Radiology
Immunology and AllergyMedicine
4
Article|31 citations·2014
Are asthmatic patients prone to bone loss?
Jae-Woo Jung, Hye‐Ryun Kang, Ju‐Young Kim, So-Hee Lee, Sun-Sin Kim, Sang‐Heon Cho
SJR Q1Annals of Allergy Asthma & Immunology
Pathology and Forensic MedicineMedicine
5
Article|29 citations·2010
Toll-like Receptor Expression on Peripheral Blood Mononuclear Cells in Asthmatics; Implications for Asthma Management
Eunyoung Chun, So-Hee Lee, Soo‐Yeon Lee, Eun-Jin Shim, Sang‐Heon Cho, Kyung‐Up Min, You-Young Kim, Heung‐Woo Park
SJR Q1Journal of Clinical Immunology
PhysiologyMedicine
6
Article|28 citations·2010
Dexamethasone-Induced FKBP51 Expression in Peripheral Blood Mononuclear Cells Could Play a Role in Predicting the Response of Asthmatics to Treatment with Corticosteroids
Eunyoung Chun, Hyun Seung Lee, Bo‐Ram Bang, Tae‐Wan Kim, So-Hee Lee, Ju Han Kim, Sang‐Heon Cho, Kyung-Up Min, You-Young Kim, Heung‐Woo Park
SJR Q1Journal of Clinical Immunology
Molecular BiologyBiochemistry, Genetics and Molecular Biology
7
Article|24 citations·2021
Effect of Lactobacillus dominance modified by Korean Red Ginseng on the improvement of Alzheimer's disease in mice
Mijung Lee, So-Hee Lee, Min‐Soo Kim, Min‐Soo Kim, Kwang‐Sung Ahn, Manho Kim, Manho Kim
SJR Q1Journal of Ginseng ResearchOA

Background: Gut microbiota influence the central nervous system through gut-brain-axis. They also affect the neurological disorders. Gut microbiota differs in patients with Alzheimer's disease (AD), as a potential factor that leads to progression of AD. Oral intake of Korean Red Ginseng (KRG) improves the cognitive functions. Therefore, it can be proposed that KRG affect the microbiota on the gut-brain-axis to the brain. Methods: Tg2576 were used for the experimental model of AD. They were divid

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|22 citations·2014
The Interaction Between Allelic Variants ofCD86andCD40LG: A Common Risk Factor of Allergic Asthma and Rheumatoid Arthritis
So-Hee Lee, Eun-Bong Lee, Eun‐Soon Shin, Jong Eun Lee, Sang‐Heon Cho, Kyung-Up Min, Heung‐Woo Park
SJR Q1Allergy Asthma and Immunology ResearchOA

Our findings suggest that a genetic interaction between CD86 and CD40LG favors the development of both AA and RA.

PhysiologyMedicine
9
Article|20 citations·2014
Influence of Chronic Sinusitis and Nasal Polyp on the Lower Airway of Subjects Without Lower Airway Diseases
Suh‐Young Lee, Soon Ho Yoon, Woo‐Jung Song, So-Hee Lee, Hye‐Ryun Kang, Sun-Sin Kim, Sang‐Heon Cho
SJR Q1Allergy Asthma and Immunology ResearchOA

CT findings suggesting chronic sinusitis and nasal polyp were associated with subclinical lower airway flow limitation even in the absence of underlying lung disease.

OtorhinolaryngologyMedicine
10
Article|18 citations·2013
New insight into the assessment of asthma using xenon ventilation computed tomography
Jae‐Woo Jung, Jae‐Woo Kwon, Tae‐Wan Kim, So-Hee Lee, Kyung-Mook Kim, Hye‐Ryun Kang, Heung‐Woo Park, Chang Hyun Lee, Jin-Mo Goo, Kyung‐Up Min, Sang‐Heon Cho
SJR Q1Annals of Allergy Asthma & Immunology
Atomic and Molecular Physics, and OpticsPhysics and Astronomy
11
Article|18 citations·2010
The effects of PG102, a water-soluble extract from Actinidia arguta, on serum total IgE levels: a double-blind, randomized, placebo-controlled exploratory clinical study
Sae‐Hoon Kim, Sunyoung Kim, So-Hee Lee, Heung‐Woo Park, Yoon‐Seok Chang, Kyung-Up Min, Sang‐Heon Cho
SJR Q1European Journal of Nutrition
PhysiologyMedicine
12
Article|16 citations·2019
Fabrication of a spherical inclusion phantom for validation of magnetic resonance-based magnetic susceptibility imaging
Jun‐Ho Kim, Jung‐Hyun Kim, So-Hee Lee, So-Hee Lee, Jinhyoung Park, Seung‐Kyun Lee, Seung‐Kyun Lee
SJR Q1PLoS ONEOA

Fabrication of a spherical multi-compartment MRI phantom is demonstrated that can be used to validate magnetic resonance (MR)-based susceptibility imaging reconstruction. The phantom consists of a 10 cm diameter gelatin sphere that encloses multiple smaller gelatin spheres doped with different concentrations of paramagnetic contrast agents. Compared to previous multi-compartment phantoms with cylindrical geometry, the phantom provides the following benefits: (1) no compartmental barrier material

Radiology, Nuclear Medicine and ImagingMedicine
13
Article|15 citations·2015
Validation of the Korean version of the European Community Respiratory Health Survey screening questionnaire for use in epidemiologic studies for adult asthma
Woo‐Jung Song, So-Hee Lee, Min‐Gyu Kang, Ju‐Young Kim, Miyoung Kim, Eun‐Jung Jo, Suh‐Young Lee, Seung Eun Lee, Min‐Hye Kim, Min‐Suk Yang, Sae‐Hoon Kim, Hye‐Ryun Kang
SJR Q2Asia Pacific AllergyOA

The present study demonstrated that the Korean version of the ECRHS screening questionnaire was comprehensible, reliable and valid. We suggest the questionnaire to be utilized in further epidemiological studies for asthma in Korean adult populations.

PhysiologyMedicine
14
Article|14 citations·2015
Reliability and Validity of a Korean Version of the Leicester Cough Questionnaire
권재우, 문지용, 김세훈, 송우정, 김민혜, 강민규, 임경환, 이소희, 이상민, 이진영, 권혁수, 김경묵

Purpose: There are no specific tools for measurement of the severity of chronic cough in Korea. We developed a Korean version of the Leicester Cough Questionnaire (LCQ) and tested its scaling and clinical properties. Methods: The LCQ was adapted for Korean conditions following a forward- backward translation procedure. All patients referred to chronic cough clinics at 5 university hospitals between May 2011 and October 2013 completed 2 questionnaires, the LCQ and the Short-Form 36 (SF-36), upon

15
Article|14 citations·2020
Blood Eosinophil Count as a Predictor of Lung Function Decline in Healthy Individuals
So-Hee Lee, Kyung‐Min Ahn, Suh‐Young Lee, Sun-Sin Kim, Heung‐Woo Park
SJR Q1The Journal of Allergy and Clinical Immunology In Practice
PhysiologyMedicine

Research Areas

PhysiologyImmunology and AllergyPharmacologyPathology and Forensic MedicineMolecular BiologyRenewable Energy, Sustainability and the Environment

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