So Young Lim
Sungkyunkwan University · Medicine
About the Lab
Professor So Young Lim's research lab specializes in pediatric craniofacial disorders, with a focus on the genetic, pathological, and clinical aspects of benign tumors and malformations such as fibrous dysplasia, neurofibromatosis, venous malformations, and capillary malformations. The lab investigates the molecular mechanisms underlying these conditions, particularly the role of somatic mutations (e.g., GNAQ) and their clinical manifestations, while also evaluating surgical outcomes and regrowth patterns post-resection. The research integrates clinical imaging, molecular diagnostics, and surgical management to improve diagnosis and treatment strategies in pediatric patients.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Dietary intake and nutritional status of individuals are important factors affecting mental health and the development of psychiatric disorders. Majority of scientific evidence relating to mental health focuses on depression, cognitive function, and dementia, and limited evidence is available about other psychiatric disorders including schizophrenia. As life span of human being is increasing, the more the prevalence of mental disorders is, the more attention rises. Lists of suggested nutritional
Neurofibromatosis type 1 is the most common tumor predisposition syndrome inherited in an autosomal dominant (100% penetrance) fashion with a wide variety of expressivity. From the perspective of plastic surgery, the most significant clinical symptoms, including disfiguration, peripheral neurologic symptoms, and skeletal abnormalities, are caused by various tumors originating from the affected nerves. Surgical removal is the standard of care for these tumors. However, the outcome is frequently u
BACKGROUND: We evaluated the preoperative natural growth pattern of craniofacial fibrous dysplasia and postoperative volume changes in patients undergoing shaving procedures. METHODS: Thirty-three patients who underwent serial computed tomography (CT) preoperatively and/or postoperatively were identified. The natural tumor growth rate was assessed using preoperative CT scans. The postoperative tumor regrowth rates and relevant variables were analyzed. RESULTS: The preoperative tumor growth rates
BACKGROUND: A somatic mutation of GNAQ (c.548G>A, p.Arg183Gln) plays a key role in capillary malformation development. The present study aimed to evaluate clinical manifestations of port-win stain (PWS) associated with this genetic mutation. METHODS: Skin tissue was obtained from 70 patients with capillary malformation who had been treated with excision for lesions. Droplet digital polymerase chain reaction was used to quantify the abundance of cells with the GNAQ mutation. RESULTS: The GNAQ mut
Research Areas
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