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Soo-Jin Yoon

Kyung Hee University · Medicine

About the Lab

Professor Soo-Jin Yoon's research lab focuses on endocrine and metabolic disorders, with a strong emphasis on diabetes mellitus, pituitary hormone-related diseases such as hyperprolactinemia and acromegaly, and the impact of environmental endocrine disruptors on metabolic health. The lab investigates the pathophysiology of these conditions, particularly their effects on bone metabolism and pancreatic beta-cell function, while also exploring protective roles of natural compounds like oleuropein against toxicological stressors. The research integrates clinical data with in vitro models to evaluate guideline-based management and therapeutic interventions.

diabetes mellitushyperprolactinemiaendocrine disruptorspancreatic beta cellsbone metabolism

Research Overview

Papers
14
Total Citations
100
Papers (5y)
6
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
6total
2022
2023
2024
2025
2026
Citations per year (5y)
43total
20222023202420252026

Selected Papers

14
1
Article|22 citations·2022
Current Status of Low-Density Lipoprotein Cholesterol Target Achievement in Patients with Type 2 Diabetes Mellitus in Korea Compared with Recent Guidelines
Soo Jin Yun, In‐Kyung Jeong, Jin‐Hye Cha, Juneyoung Lee, Ho‐Chan Cho, Sung Hee Choi, SungWan Chun, Hyun Jeong Jeon, Ho‐Cheol Kang, Sang Soo Kim, Seung‐Hyun Ko, Gwanpyo Koh
SJR Q1Diabetes & Metabolism JournalOA

BACKGROUND: We evaluated the achievement of low-density lipoprotein cholesterol (LDL-C) targets in patients with type 2 diabetes mellitus (T2DM) according to up-to-date Korean Diabetes Association (KDA), European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS), and American Diabetes Association (ADA) guidelines. METHODS: This retrospective cohort study collected electronic medical record data from patients with T2DM (≥20 years) managed by endocrinologists from 15 hospitals in

SurgeryMedicine
2
Article|21 citations·2024
Effect of Hyperprolactinemia on Bone Metabolism: Focusing on Osteopenia/Osteoporosis
Soo Jin Yun, Hyunji Sang, So Young Park, Sang Ouk Chin
SJR Q1International Journal of Molecular SciencesOA

Prolactin is a hormone secreted from lactotroph cells in the anterior pituitary gland to induce lactation after birth. Hyperprolactinemia unrelated to lactation is a common cause of amenorrhea in women of a childbearing age, and a consequent decrease in the gonadotropin-releasing hormone (GnRH) by a high prolactin level can result in decreased bone mineral density. Osteoporosis is a common skeletal disorder characterized by decreased bone mineral density (BMD) and quality, which results in decre

Orthopedics and Sports MedicineMedicine
3
Article|19 citations·2021
Descriptive Epidemiology and Survival Analysis of Acromegaly in Korea
Soo Jin Yun, Jungkuk Lee, So Young Park, Sang Ouk Chin
SJR Q2Journal of Korean Medical ScienceOA

The annual incidence rate of Korean patients with acromegaly was similar to that reported in previous studies. Using nationwide population data, our study emphasized the importance of treatment in acromegaly patients.

Endocrinology, Diabetes and MetabolismMedicine
4
Article|12 citations·2021
Descriptive Epidemiology and Survival Analysis of Prolactinomas and Cushing’s Disease in Korea
Jin Sun Park, Soo Jin Yun, Jungkuk Lee, So Young Park, Sang Ouk Chin
SJR Q1Endocrinology and MetabolismOA

Overall, the incidence of prolactinoma and Cushing's disease was similar with those found previously, but the prevalence of two diseases were inconsistent when compared with the early studies. The present study also proposed necessity of treatment in Cushing's disease for improving the survival rate.

Endocrinology, Diabetes and MetabolismMedicine
5
Article|11 citations·2013
포스터 디자인의 메타포(Metaphor)적 표현 유형 분석 - 2000~2008년도 바르샤바 국제 포스터 비엔날레 금상 및 은상 수상작을 중심으로 -
윤수진, 장미경
브랜드디자인학연구

현대 포스터는 그 활용성과 메시지전달 기능의 확장으로 인해 시각적 정보매체로서의 일차적인 목적 위에 문화 예술적인 의미가 더해진 그래픽 아트(Graphic Arts)로서의 위치를 확고히 다지고 있다. 현대인들은 다양한 매스커뮤니케이션 기법의 영향으로 직접적이고 단순하게 표현된 이미지 표현 기법보다는 은유적이고 예술적으로 표현된 비주얼 이미지에 더 많은 흥미를 일으킨다. 따라서 포스터 디자인의 아이캣처(Eye Catcher)로서 적용되는 비주얼 이미지도 설명을 필요로 하지 않는 직접적이고 단순한 접근보다, 대중들 각자에게 정보해석의 여운을 남기고 기억작용을 강화시켜주는 메타포 적(Metaphor) 표현이 효과적이다. 본 연구는 현대 포스터 디자인의 다원적 표현 유형 분석을 통해 포스터 디자인의 시대적 흐름과 커뮤니케이션 매체로서의 기능 및 그 위상을 확인하기 위한 목적을 갖고 있다. 그를 위해서 포스터의 장르, 메타포의 개념의 이해, 시각적 메타포의 역할 및 기능을 고찰하였으며, 이미

6
Article|7 citations·2021
Oleuropein attenuates the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-perturbing effects on pancreatic β-cells
Eun Mi Choi, Kwang Sik Suh, Soo Jin Yun, Jinsun Park, So Young Park, Sang Ouk Chin, Suk Chon
SJR Q2Journal of Environmental Science and Health Part A

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an endocrine disrupting compound and persistent organic pollutant that has been associated with diabetes in several epidemiological studies. Oleuropein, a major phenolic compound in olive fruit, is a superior antioxidant and radical scavenger. This study aimed to examine the effects of oleuropein against TCDD-induced stress response in a pancreatic beta cell line, INS-1 cells. Cells were pre-incubated with various concentrations of oleuropein and the

Organic ChemistryChemistry
7
Preprint|3 citations·2021
Descriptive epidemiology and survival analysis of acromegaly in Korea
Soo Jin Yun, Jungkuk Lee, Jinsun Park, So Young Park, Sang Ouk Chin
Research SquareOA

Abstract Acromegaly is a rare, slowly progressive disease. Its mechanism is not fully understood, and epidemiological research on Korean patients with acromegaly is scarce. To determine the incidence and prevalence of acromegaly and assess the comorbidities and survival benefits based on treatment options. This nationwide population-based cohort study was conducted using data of the Korean Health Insurance Review and Assessment claims database to evaluate the incidence of newly diagnosed acromeg

Endocrinology, Diabetes and MetabolismMedicine
8
Article|3 citations·2014
인쇄매체 타이포그래피의 조형언어 형식에 관한 연구
윤수진, 장미경
브랜드디자인학연구

오늘날의 시각매체(Visual Media) 환경은, 커뮤니케이션 메시지를 수용자(Audience)에게 효과적으로 전달하기 위해 메커니즘의 형식도 점차 다각화, 심층화되어 가고 있는 추세이다. 그러한 변화에 따라 인쇄매체(Print Media) 디자인의 타이포그래피도 단순히「보기 좋은 글자구성」의 차원을 넘어 핵심적 디자인 요소로서 이해하고 조형적인 차별성과 함께 시각적 흥미와 주목성이 표출되어야 하며, 광고를 접하는 소비자에게 브랜드가 추구하는 메시지를 즉시적이며 설득적으로 인식시킬 수 있도록 하는 시각적인 표현기법 연구가 요구된다. 본 연구는 현 시대의 중심적 시각 커뮤니케이션 기능인 조형언어적 타이포그래피의 특성을 인쇄매체 디자인에 한하여 심화 연구하였으며, 그 활용 가능성을 제시함으로써 향후 포스터디자인 및 인쇄매체 광고에 적용되는 타이포그래피의 발전적 양식화를 위한 이론적 근거를 제시하고자 하였다. 그에 따라, 조형언어적 타이포그래피가 인쇄매체 디자인에서 적용된 유형을 3가지

9
Article|1 citations·2011
픽토리얼 타이포그래피(Pictorial typography)의 수사학적 표현 연구
윤수진, 임헌혁
디지털디자인학연구

정보의 홍수 속에 살아가는 현대인들은 다양한 커뮤니케이션 활동을 통해 의사소통을 하고 있다. 커뮤니케이션의 중심 기능을 하는 언어는 고대 그리스 시대의 수사학을 비롯하여 주요 학문의 영역으로서 오래전부터 연구의 대상이었다. 수사학이 언어적 화술로 남을 설득하는 기술이라면 비주얼커뮤니케이션은 시각적 이미지로 고객을 설득하는 역할을 하기 때문에 수사학과 비주얼커뮤니케이션은 일맥상통하는 기능이 있음을 알 수 있다. 따라서 시각적 의사소통을 보다 원활하게 하기 위해서는 커뮤니케이션의 핵심이라고 할 수 있는 타이포그래피의 다양하고 창조적인 시각 표현이 요구되며, 그런 이유로 짧은 시간과 한정된 지면 속에서 함축된 메시지를 효과적으로 전달할 수 있는 픽토리얼 타이포그래피는 강한 메시지를 전달 할 수 있는 수단이 될 수 있다. 본 논문에서는 전통적 언어표현 연구의 수사학에서 현대적 시각언어의 수사적 표현법으로 발전하는 전체적인 흐름을 통해, 시각적 분류방법을 재 정의하고 비주얼커뮤니케이션 디자인

10
Article|1 citations·1996
Depression tendency and Family function of Hemodialysis patients.
Kyun Sang Lee, Soo Jin Yun, Ho Seong Moon, Moon Jae Kim
Gajeong yihag hoeji
Clinical PsychologyPsychology
11
Article|0 citations·2024
7050 Effect of Spironolactone On Reducing Sugar-Induced Cellular Damage In MC3T3-E1 Osteoblastic Cells
Soo Jin Yun, Hyunji Sang, So Young Park, Kwang Sik Suh, Hyun-Sook Kim, Sang Ouk Chin
SJR Q2Journal of the Endocrine SocietyOA

Abstract Disclosure: S. Yun: None. H. Sang: None. S. Park: None. K. Suh: None. H. Kim: None. S. Chin: None. Background: In diabetes, prolonged hyperglycemia causes oxidative stress, resulting in pancreatic beta cells' dysfunction and diabetic complications. Oxidative stress can inhibit osteoblast differentiation and induce dysfunction and apoptosis. Spironolactone is an aldosterone antagonist used to treat hypertension and heart failure. In this study, we observed whether spironolactone can redu

Cancer ResearchBiochemistry, Genetics and Molecular Biology
12
Article|0 citations·2025
708-P: Comparative Effectiveness of Structured Interventions in the Korean Diabetes Prevention Study (KDPS) vs. the Korean Genome and Epidemiology Study (KOGES)
Soo Jin Yun, Hyunji Sang, SUNHAN SHIN, Jihye Choi, YOUNGJI YOON, Suk Chon, Jeong‐Taek Woo
SJR Q1Diabetes

Introduction and Objective: This study aimed to compare the effectiveness of the Korean Diabetes Prevention Study (KDPS) and the Korean Genome and Epidemiology Study (KoGES) in preventing diabetes among prediabetes populations. The primary focus was to evaluate the outcomes of different intervention strategies and their impact on diabetes progression. Methods: KDPS employed three intervention strategies: Standard Management (STM) with biannual education; Lifestyle Modification (LSM) with an inte

Complementary and alternative medicineMedicine
13
Article|0 citations·2023
742-P: Diabetes Prevention Effect of Practically Applicable Intervention in Clinical Settings Based on the Korean Diabetes Prevention Study (KDPS)
Suk Chon, Soo Jin Yun, Jeong‐Taek Woo, THE KOREAN DIABETES PREVENTION STUDY INVESTIGATORS
SJR Q1Diabetes

Background: The Korean Diabetes Prevention Study (KDPS, NCT02981121), a national clinical study to prevent T2DM, started in 2016 and is currently ongoing. This study was to evaluate the preventive effect of KDPS intervention for up to 1 year. Methods: The enrollment criteria are adults aged 30-70 with a BMI ≥ 23 kg/m2 at high risk of T2DM. Three Intervention methods are hospital-based lifestyle modification (hLSM) developed by Korean Diabetes Association, metformin (MET, 250mg~1000mg) and contro

Nutrition and DieteticsNursing
14
Article|0 citations·2026
Effects of spironolactone on cytotoxic damage in osteoblasts
So Park, Kwang Sik Suh, Hyun-Sook Kim, Soo Jin Yun, Hyunji Sang, Sang Ouk Chin
Experimental and Therapeutic MedicineOA

Chronic hyperglycemia in diabetes elevates oxidative stress, damaging pancreatic β-cells and worsening complications. Oxidative stress also disrupts osteoblast function, suppresses their maturation and triggers apoptosis, thereby contributing to bone fragility. Spironolactone, an aldosterone receptor antagonist prescribed for the treatment of hypertension and heart failure, has potential protective effects on skeletal health. The present study examined whether spironolactone could protect osteob

Molecular BiologyBiochemistry, Genetics and Molecular Biology

Research Areas

Endocrinology, Diabetes and MetabolismSurgeryOrthopedics and Sports MedicineOrganic ChemistryClinical PsychologyNutrition and Dietetics

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