Soo Min Ahn
Yonsei University · Medicine
About the Lab
Professor Soo Min Ahn's research lab specializes in bariatric and metabolic surgery, focusing on the physiological and molecular mechanisms underlying the metabolic benefits of gastrointestinal surgeries beyond simple weight loss. The lab investigates the roles of gastric and intestinal interventions in regulating glucose homeostasis and body weight, particularly in the context of type 2 diabetes and severe obesity. Their work spans preclinical models, such as ZDF rats, and clinical studies in adolescents and adults, emphasizing long-term outcomes and the shift from purely weight-reducing to metabolic-disease-modifying surgical approaches. The lab also explores the implications of incidental findings in thyroid imaging, reflecting a broader interest in metabolic and endocrine health.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Offering surgery to treat metabolic disease or diabetes rather than as a mere weight-reduction therapy changes demographical and clinical characteristics of surgical candidates. This has important and practical ramifications for clinical care and support consideration of metabolic/diabetes surgery as a novel practice distinct from traditional bariatric surgery.
OBJECTIVE: To elucidate the specific role of gastric vs. intestinal manipulations in the regulation of body weight and glucose homeostasis. DESIGN AND METHODS: The effects of intestinal bypass alone (duodenal-jejunal bypass -DJB) and gastric resection alone (SG) in Zucker Diabetic Fatty (ZDF) rats were compared. Additional animals underwent a combination procedure (SG + DJB). Outcome measures included changes in weight, food intake (FI), oral glucose tolerance (GT) and gut hormones. RESULTS: DJB
Conventional nonsurgical management of severe obesity in the pediatric population and adolescents has focused on a multidisciplinary approach involving diet, exercise, behavioral modification, and to some extent, pharmaceuticals. Although nonsurgical strategies provide a certain degree of effective weight reduction, most of the severely obese adolescents suffer from a high relapse rate. In recent studies, long-term outcomes of bariatric surgery for severely obese adolescents have shown sustainab
The increased sensitivity of many imaging devices has increased the identification of asymptomatic nodules in the thyroid gland. In this study we investigated the actual incidence of nonpalpable thyroid nodules and occult carcinoma in women. Between January and June 2003, among the women who were scheduled to undergo breast ultrasonography, 697 without palpable thyroid nodules were screened for thyroid nodules. They were classified into four categories according to ultrasonographic findings: neg
Conventional bariatric operations, including Roux-en-Y gastric bypass (RYGB), laparoscopic adjustable gastric banding, and biliopancreatic diversion (BPD) appear to be a safe and effective treatment for many severely obese patients with type 2 diabetes mellitus (T2DM). These operations improve glucose homeostasis through a variety of mechanisms, however, not only due to reduced food intake and body weight. Research to elucidate the weight-independent antidiabetic mechanisms of gastrointestinal (
Abstract Background On November 25, 2021, the IFSO-Asia–Pacific Chapter (IFSO-APC) Virtual Meeting 2021 was held online, and the representatives from the Asia–Pacific region presented 10 years of change in bariatric/metabolic surgery and the influence of COVID-19 in the special session of “IFSO-APC National Reports 2010–2020”. We herein report the summarized data. Methods National bariatric/metabolic surgery data, which included the data of 2010 and 2020, were collected from the representatives
Hypersplenism, secondary to portal hypertension, is common in hepatocellular carcinoma (HCC) with liver cirrhosis. Hepatic resection in the patient with hypersplenic thrombocytopenia (HSTC) may cause a perioperative bleeding episode and sometimes, liver failure. In order to investigate the effect of concomitant splenectomy in HCC patients with HSTC, clinical parameters are retrospectively reviewed for 18 HCC patients who underwent hepatic resection with or without splenectomy. Among 581 HCC pati
In the pediatric population with choledochal cyst, total intracorporeal Roux-en-Y hepaticojejunostomy and jejunojejunostomy during laparoscopic surgery is feasible without the need for exteriorization of the bowel.
Background/Aims: Autoimmune gastritis (AIG) is a corpus-dominant atrophic gastritis in which patients are positive for antiparietal cell antibody (APCA) and/or anti-intrinsic factor antibody. The risk of developing gastric cancer in patients with AIG remains unclear, and reliable frequency data of AIG in patients with gastric cancer are lacking. Methods: We included 624 Korean patients with gastric tumors (612 gastric cancers and 12 neuroendocrine tumors) who had APCA results and were available
1945년 ‘해방’은 제각기 다른 이유로 제국 전역에 흩어져 있었던 사람들을 대규모로 이동시켰다. 귀환은 사람들로 하여금 물리적‧정신적 감각의 급진적인 변화를 요구하는 과정이었고, 또한 많은 이들이 공유했던 집단 경험이었다. 대개 해방 직후 한반도에서 쓰인 귀환서사는 유랑자로서 겪은 고달픈 여정을 바탕으로, 이후 새로운 국민국가에 소속됨으로써 얻을 수 있을 정신적 물리적 안정감을, 그리고 그것에 대한 낙관적인 기대를 표현하는 단순하고 폐쇄적인 서사의 형태를 취했다. 그러나 손소희의 『남풍』은 기존의 귀환서사의 구조를 따르면서도, 민족주의 및 국민국가 이데올로기로 포섭되지 않는다. 이 차이는 작품의 주요 화자가 식민지민 디아스포라라는 점에 기인한다. 역사적으로 큰 변화를 맞이할 때마다 가장 먼저 도태되고 소외되는 이들은 ‘해방’ 이후에도 여전히 난민화된다. ‘해방’, 귀환의 장면은 난민, 디아스포라들의 타자화 뒤에 오는 것이기에 기만적인 것으로 그려질 수밖에 없고, 『남풍』은 이 역사
The PIB preserved the plasma insulin levels and the wider beta-cell area over time and facilitated insulin signaling in the visceral fats. It could be considered as a possible reconstruction strategy for diabetic gastric cancer patients.
Research Areas
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