Skip to main content

Sung-hwan Yoo

Yonsei University · Medicine

About the Lab

Professor Sung-hwan Yoo's research lab focuses on translational biomedical research with a strong emphasis on liver diseases, particularly chronic hepatitis B and non-alcoholic fatty liver disease (NAFLD). The lab investigates clinical risk factors, diagnostic biomarkers, and innovative interventions—such as virtual reality for anxiety reduction in endoscopic procedures—while also advancing medical imaging and AI-driven solutions for point cloud segmentation in clinical and radiological applications. Their work bridges clinical medicine, medical technology, and artificial intelligence to improve patient outcomes and diagnostic accuracy.

liver diseasechronic hepatitis BNAFLDmedical AIvirtual reality in medicine

Research Overview

Papers
26
Total Citations
124
Papers (5y)
20
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
20total
2021
2022
2023
2024
2025
Citations per year (5y)
124total
20212022202320242025

Selected Papers

15
1
Article|26 citations·2022
Association between Sarcopenic Obesity Status and Nonalcoholic Fatty Liver Disease and Fibrosis
Wolhwa Song, Sung Hwan Yoo, Jinsun Jang, Su Jung Baik, Byoung Kwon Lee, Hyun Woong Lee, Jong Suk Park
SJR Q1Gut and LiverOA

These results demonstrated that sarcopenic obesity was independently associated with NAFLD and liver fibrosis and increased the risk of NAFLD and liver fibrosis more than obesity or sarcopenia alone.

EpidemiologyMedicine
2
Article|23 citations·2023
Human Vision Based 3D Point Cloud Semantic Segmentation of Large-Scale Outdoor Scenes
Sung Hwan Yoo, Yeonjeong Jeong, Maryam Jameela, Gunho Sohn

This paper proposes EyeNet, a novel semantic segmentation network for point clouds that addresses the critical yet often overlooked parameter of coverage area size. Inspired by human peripheral vision, EyeNet overcomes the limitations of conventional networks by introducing a simple but efficient multi-scale input and a parallel processing network with connection blocks between parallel streams. The proposed approach effectively addresses the challenges of dense point clouds, as demonstrated by

Computational MechanicsEngineering
3
Article|22 citations·2023
Relieving Anxiety Through Virtual Reality Prior to Endoscopic Procedures
Yuna Kim, Sung Hwan Yoo, Jaeyoung Chun, Jie‐Hyun Kim, Young Hoon Youn, Hyojin Park
SJR Q2Yonsei Medical JournalOA

PURPOSE: Endoscopic procedures can cause anxiety, which can lead to more uncomfortable, difficult, and incomplete procedures, in addition to greater use of sedative medication. Here, we investigate whether exposing patients to virtual reality (VR) prior to endoscopic procedures can reduce their anxiety levels. MATERIALS AND METHODS: Forty patients at Gangnam Severance Hospital were enrolled and divided into the VR group and the control group. Patients in the VR group were exposed to VR prior to

Pediatrics, Perinatology and Child HealthMedicine
4
Article|13 citations·2021
Risk assessment of hepatocellular carcinoma and liver‐related events using ultrasonography and transient elastography in patients with chronic hepatitis B
Sung Hwan Yoo, Tae Seop Lim, Hyun Woong Lee, Ja Kyung Kim, Jae Seung Lee, Hye Won Lee, Beom Kyung Kim, Jun Yong Park, Do Young Kim, Sang Hoon Ahn, Jung Il Lee, Kwan Sik Lee
SJR Q2Journal of Viral HepatitisOA

Cirrhosis has prognostic value. We investigated whether the combined use of ultrasonography (US) and transient elastography (TE) to diagnose cirrhosis is beneficial for the risk assessment of hepatocellular carcinoma (HCC) and liver-related events in patients with chronic hepatitis B (CHB). A total of 9300 patients with CHB who underwent US and TE in two institutions between 2006 and 2018 were enrolled. TE value ≥13 kPa was set to indicate cirrhosis. Patients were divided into four groups: US(+)

EpidemiologyMedicine
5
Article|11 citations·2021
Anti-HBc IgG Levels: A Predictor of HBsAg Seroclearance in Chronic Hepatitis B Patients with Nucleos(t)ide Analogue-Induced HBeAg Seroclearance
Saein Kim, Sung Hwan Yoo, Jung Il Lee, Sora Kim, Hye Young Chang, Dokyun Kim, Seok Hoon Jeong, Kwan Sik Lee, Hyun Woong Lee
SJR Q2Digestive Diseases and SciencesOA

BACKGROUND/AIMS: We investigated the efficiency of the indirect ratio of anti-HBc IgG at predicting HBsAg seroclearance in patients with nucleos(t)ide analogue (NA)-induced HBeAg seroclearance. METHODS: We performed a retrospective study that included 366 chronic hepatitis B patients (March 2007 to December 2016) at a single tertiary hospital. These patients were HBsAg seropositive, and experienced NA-induced HBeAg seroclearance. The indirect ratio of light absorbance of anti-HBc IgG levels were

EpidemiologyMedicine
6
Article|7 citations·2022
Baseline and on‐treatment HBcrAg levels as predictors of HBeAg seroconversion in chronic hepatitis B patients treated with antivirals
Soo Young Hwang, Sung Hwan Yoo, Hye Young Chang, Sora Kim, Jung Il Lee, Kwan Sik Lee, Young Youn Cho, Kim Hyung Joon, Hyun Woong Lee
SJR Q2Journal of Viral HepatitisOA

Abstract HBeAg seroconversion is an important treatment endpoint. We aimed to identify predictors of seroconversion using serum HBsAg and hepatitis B core‐related antigen (HBcrAg) in HBeAg‐positive patients treated with nucleos(t)ide analogs (NAs). Data and samples from 70 HBeAg‐positive patients treated with entecavir or tenofovir between January 2007 and December 2017 were retrospectively analysed. The mean follow‐up period was 11 years. The predictive power for HBeAg seroconversion of HBcrAg

EpidemiologyMedicine
7
Article|5 citations·2023
Loss of Krüppel-like factor-10 facilitates the development of chemical-induced liver cancer in mice
Sung Hwan Yoo, Ji Hae Nahm, Woon Kyu Lee, Hyun Woong Lee, Hye Young Chang, Jung Il Lee
SJR Q1Molecular MedicineOA

BACKGROUND: Krüppel-like factor 10 (KLF10) is involved in a positive feedback loop that regulates transforming growth factor β (TGFβ) signaling, and TGFβ plays an important role in the pathogenesis of liver disease. Here, we investigated whether KLF10 deletion affects the development of liver fibrosis and hepatocellular carcinoma (HCC). METHODS: We induced KLF10 deletion in C57BL/6 mice. Liver fibrosis was induced by feeding a diet high in fat and sucrose (high-fat diet [HFD]), whereas HCC was p

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|4 citations·2022
Effect of Drinking Warm Water on Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia
Hong Jin Yoon, Young Hoon Youn, Sung Hwan Yoo, Se‐Yeon Jeon, Hyojin Park
SJR Q1Journal of Neurogastroenterology and MotilityOA

Drinking warm water dramatically reduces esophageal food retention and significantly improves the quality of esophageal preparation. This simple protocol is quite useful, safe, and cost-effective in the preparation of achalasia patients for POEM.

GastroenterologyMedicine
9
Article|3 citations·2023
The care cascade for hepatitis C virus and prognosis of chronic hepatitis C patients treated with antiviral agents in a tertiary hospital
Sung Hwan Yoo, Myung Kim, So-Ra Kim, Jung Il Lee, Kwan Sik Lee, Hyun Woong Lee, Jin Hong Lim
SJR Q2BMC GastroenterologyOA

Abstract Background Some studies have analyzed the frequency of HCV RNA testing and actual treatment among anti-HCV positive patients in Korea, which has a low prevalence of HCV infection. This study aimed to analyze the diagnosis process, treatment results, and prognosis according to care cascade in patients who are anti-HCV positive. Methods Three thousand two hundred fifty-three anti-HCV positive patients presented to a tertiary hospital between January 2005 and December 2020. The number of p

HepatologyMedicine
10
Article|3 citations·2025
EyeNet++: A Multiscale and Multidensity Approach for Outdoor 3-D Semantic Segmentation Inspired by the Human Visual Field
Sung Hwan Yoo, Yeonjeong Jeong, Mohammad Moein Sheikholeslami, Gunho Sohn
SJR Q1IEEE Transactions on Geoscience and Remote SensingOA

In processing dense 3D point cloud data for semantic segmentation, current deep learning networks face challenges maintaining a sufficient neighbourhood search area, limiting their accuracy and scalability. Inspired by the human visual field, EyeNet++ introduces a novel multi-scale and multi-density input strategy, ensuring extensive spatial coverage of a neighbourhood search area while preserving detail. The network is designed to maximize feature extraction from these diverse inputs through in

Environmental EngineeringEnvironmental Science
11
Article|2 citations·2023
Selective hanging maneuver and rubber band retraction technique for pure laparoscopic donor right hepatectomy
Man Ki Ju, Sung Hwan Yoo, Gi Hong Choi, Dong Sup Yoon, Jin Hong Lim
SJR Q2Asian Journal of SurgeryOA

The selective liver parenchymal hanging maneuver and rubber band retraction technique is a simple and effective pure laparoscopic procedure for donor hepatectomy. Our results demonstrate the safety and feasibility of this technique.

HepatologyMedicine
12
Article|2 citations·2022
Long-term survival after CCRT and HAIC followed by ALPPS for hepatocellular carcinoma with portal vein invasion: a case report
In-Jung Kim, Sung Hwan Yoo, Jung Il Lee, Kwan Sik Lee, Hyun Woong Lee, Jin Hong Lim
SJR Q1Journal of Liver CancerOA

There are various methods for treating advanced hepatocellular carcinoma with portal vein invasion, such as systemic chemotherapy, transarterial chemoembolization, transarterial radioembolization, and concurrent chemoradiotherapy. These methods have similar clinical efficacy but are designed with a palliative aim. Herein, we report a case that experienced complete remission through "associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)" after concurrent chemoradioth

HepatologyMedicine
13
Article|1 citations·2022
Low Incidence of Hepatocellular Carcinoma after Antiviral Therapy in Patients with Chronic Hepatitis C and Hemophilia
In Jung Kim, Sung Hwan Yoo, So-Ra Kim, Young Youn Cho, Ki Young Yoo, Hyung Joon Kim, Hyun Woong Lee
SJR Q1Journal of Clinical MedicineOA

Background: Hepatocellular carcinoma (HCC) rarely develops in patients with chronic hepatitis C (CHC) who achieve sustained virological response (SVR). We assessed the incidence of HCC in CHC patients with hemophilia after treatment with pegylated interferon plus ribavirin (PegIFN/RBV) and direct-acting antivirals (DAAs). Methods: Patients (n = 202) were enrolled between March 2007 and July 2019. A total of 139 patients were treated with PegIFN/RBV (genotype 1, n = 98; genotype 2, n = 41). Sixty

HepatologyMedicine
14
Preprint|1 citations·2023
Human Vision Based 3D Point Cloud Semantic Segmentation of Large-Scale Outdoor Scene
Sung Hwan Yoo, Yeongjeong Jeong, Maryam Jameela, Gunho Sohn
arXiv (Cornell University)OA

This paper proposes EyeNet, a novel semantic segmentation network for point clouds that addresses the critical yet often overlooked parameter of coverage area size. Inspired by human peripheral vision, EyeNet overcomes the limitations of conventional networks by introducing a simple but efficient multi-contour input and a parallel processing network with connection blocks between parallel streams. The proposed approach effectively addresses the challenges of dense point clouds, as demonstrated b

Environmental EngineeringEnvironmental Science
15
Article|1 citations·2023
Risk of dementia in the elderly with non-alcoholic fatty liver disease: A nested case-control study in the Republic of Korea
Sung Hwan Yoo, Ju-Young Park, Hye Sun Lee, Hyun Woong Lee, Jung Il Lee
SJR Q3Annals of the Academy of Medicine SingaporeOA

Introduction: Non-alcoholic fatty liver disease (NAFLD) is known to be associated with metabolic syndrome of which diabetes is an important component. Although diabetes is a known risk factor for dementia, studies on the association between NAFLD and dementia still produce conflicting results. This study aimed to determine whether NAFLD would be a risk factor for the development of dementia in an elderly population. Method: This study included 107,369 subjects aged ≥60 years in the Korean Nation

EpidemiologyMedicine

Research Areas

EpidemiologyHepatologyEnvironmental EngineeringSurgeryComputational MechanicsPediatrics, Perinatology and Child Health

Dive deeper into Sung-hwan Yoo's research on Nubint

Open this lab's papers in the app to read with AI, summarize, and cite in your writing.