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Sung Won No

Hanyang University · Medicine

About the Lab

Professor Sung Won No's research lab focuses on the neurobiological and genetic underpinnings of psychiatric disorders, with a particular emphasis on addiction, suicide, and mental health service utilization. The lab investigates brain structure and function in conditions such as Internet use disorder and alcohol dependence, integrating neuroimaging, molecular genetics, and clinical epidemiology. A key focus is understanding the interplay between genetic factors—such as GABRA2 variants—and behavioral responses to substances, as well as the socioeconomic determinants of mental health outcomes. The lab also examines treatment-related complications, such as clozapine-induced cardiomyopathy, highlighting translational research bridging psychiatry and internal medicine.

psychiatric geneticsmental health servicessuicide preventionneuroimagingaddiction neuroscience

Research Overview

Papers
129
Total Citations
1,976
Papers (5y)
38
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
38total
2021
2022
2023
2024
2025
Citations per year (5y)
203total
20212022202320242025

Selected Papers

15
1
Review|72 citations·2016
Neurobiological findings related to Internet use disorders
Byeongsu Park, Doug Hyun Han, Sungwon Roh
SJR Q1Psychiatry and Clinical NeurosciencesOA

In the last 10 years, numerous neurobiological studies have been conducted on Internet addiction or Internet use disorder. Various neurobiological research methods - such as magnetic resonance imaging; nuclear imaging modalities, including positron emission tomography and single photon emission computed tomography; molecular genetics; and neurophysiologic methods - have made it possible to discover structural or functional impairments in the brains of individuals with Internet use disorder. Spec

Psychiatry and Mental healthMedicine
2
Article|68 citations·2010
Role of GABRA2 in Moderating Subjective Responses to Alcohol
Sungwon Roh, Sachio Matsushita, Sachiko Hara, Hitoshi Maesato, Toshifumi Matsui, Go Suzuki, Tomohiro Miyakawa, Vijay A. Ramchandani, Ting‐Kai Li, Higuchi Susumu
Alcoholism Clinical and Experimental ResearchOA

BACKGROUND: Human twin studies have shown that certain responses to alcohol, including subjective perceptions, are genetically influenced. Previous studies have provided evidence that a low level of response to alcohol predicts future alcohol use disorders in humans. Recent genetic studies suggest an association between alcohol dependence and genetic variation in the γ-aminobutyric acid A (GABA(A)) receptor α2 subunit gene (GABRA2). Based on a haplotypic association of alcohol dependence with GA

Molecular BiologyBiochemistry, Genetics and Molecular Biology
3
Article|58 citations·2017
Suicide rates across income levels: Retrospective cohort data on 1 million participants collected between 2003 and 2013 in South Korea
Sang‐Uk Lee, In‐Hwan Oh, Hong Jin Jeon, Sungwon Roh
SJR Q1Journal of EpidemiologyOA

Our results illuminate the relationship between socioeconomic position and suicide rates and can be used to design and implement future policies on suicide prevention.

Clinical PsychologyPsychology
4
Review|40 citations·2016
Mental health services and R&D in South Korea
Sungwon Roh, Sang‐Uk Lee, Minah Soh, Vin Ryu, Hyunjin Kim, Jungwon Jang, Hee Young Lim, Mina Jeon, Jong‐Ik Park, SungKu Choi, Kyooseob Ha
SJR Q1International Journal of Mental Health SystemsOA

World Health Organization has asserted that mental illness is the greatest overriding burden of disease in the majority of developed countries, and that the socioeconomic burden of mental disease will exceed that of cancer and cardiovascular disorders in the future. The life-time prevalence rate for mental disorders in Korea is reported at 27.6 %, which means three out of 10 adults experience mental disorders more than once throughout their lifetime. Korea's suicide rate has remained the highest

Social PsychologyPsychology
5
Article|37 citations·2014
Sociodemographic factors associated with the use of mental health services in depressed adults: results from the Korea National Health and Nutrition Examination Survey (KNHANES)
Se Jin Park, Hong Jin Jeon, Ju Young Kim, Sohye Kim, Sungwon Roh
SJR Q1BMC Health Services ResearchOA

BACKGROUND: The aims of this study were to determine the utilization of mental health services (MHSs) by adults with a depressive mood and to identify the influencing sociodemographic factors, using a nationwide representative Korean sample. METHODS: The study included 2735 subjects, aged 19 years or older, who had experienced a depressive mood continuously for over 2 weeks within the previous year, using the data from the KNHANES IV (Fourth Korea National Health and Nutrition Examination Survey

Social PsychologyPsychology
6
Article|30 citations·2006
Cardiomyopathy associated with clozapine.
Sungwon Roh, Dong Hyun Ahn, Jung Hyun Nam, Byung Hwan Yang, Bang Hun Lee, Yang Suk Kim
SJR Q1Experimental and Clinical Psychopharmacology

Clozapine is an atypical antipsychotic agent that is more effective than the standard neuroleptics currently used for treating refractory schizophrenia. In addition, clozapine is a drug with few extrapyramidal side effects. However, clozapine is also associated with potentially serious adverse effects, such as cardiac complications as well as agranulocytosis. Clozapine-related cardiomyopathy has not been previously reported in East Asia. This report describes a 31-year-old Korean male patient wi

Psychiatry and Mental healthMedicine
7
Article|26 citations·2013
Acute effects of mecamylamine and varenicline on cognitive performance in non-smokers with and without schizophrenia
Sungwon Roh, Susanne S. Hoeppner, David Schoenfeld, Catherine A. Fullerton, Luke E. Stoeckel, A. Eden Evins
SJR Q1PsychopharmacologyOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|17 citations·2021
Suicidal ideation among the elderly living in the community: Correlation with living arrangement, subjective memory complaints, and depression
Dabin Kim, Daeho Kim, Kounseok Lee, Nayeon Choi, Sungwon Roh
SJR Q1Journal of Affective Disorders
Clinical PsychologyPsychology
9
Article|15 citations·2017
Scientific Evidence for the Addictiveness of Tobacco and Smoking Cessation in Tobacco Litigation
Sungwon Roh
SJR Q2Journal of Preventive Medicine and Public HealthOA

Smokers keep smoking despite knowing that tobacco claims many lives, including their own and others'. What makes it hard for them to quit smoking nonetheless? Tobacco companies insist that smokers choose to smoke, according to their right to self-determination. Moreover, they insist that with motivation and willpower to quit smoking, smokers can easily stop smoking. Against this backdrop, this paper aims to discuss the addictive disease called tobacco use disorder, with an assessment of the addi

PhysiologyMedicine
10
Article|11 citations·2018
Smoking as a Preventable Risk Factor for Rheumatoid Arthritis: Rationale for Smoking Cessation Treatment in Patients with Rheumatoid Arthritis
Sungwon Roh
SJR Q2Journal of Rheumatic DiseasesOA

Rheumatoid arthritis (RA) is a chronic inflammatory disease of multifactorial etiology. Smoking is considered one of the most established environmental risk factors for RA development and severity. A large proportion of patients with RA have a high prevalence of smoking history. Previous studies have provided evidence suggesting that smoking is associated with the development of RA. Smoking has been associated with several pathogenic mechanisms on RA development such as oxidative stress, inflamm

RheumatologyMedicine
11
Article|11 citations·2008
Effects of haloperidol and risperidone on the expression of heat shock protein 70 in MK-801-treated rat C6 glioma cells
Kyungsoo Roh, Sungwon Roh, Byung-Hwan Yang, Jun‐Seok Lee, Young Gyu Chai, Mi Ran Choi, Yong Chon Park, Dai‐Jin Kim, Daeho Kim, Joonho Choi, Seok Hyeon Kim
SJR Q1Progress in Neuro-Psychopharmacology and Biological Psychiatry
Molecular BiologyBiochemistry, Genetics and Molecular Biology
12
Article|8 citations·2020
Effects of various antipsychotics on driving-related cognitive performance in adults with schizophrenia
Seokmin Noh, Euihyeon Na, Se Jin Park, Seok Hyeon Kim, A. Eden Evins, Sungwon Roh
SJR Q1Journal of Psychiatric Research
Psychiatry and Mental healthMedicine
13
letter|5 citations·2015
Effects of LEP, LEPR, ADIPOQ, MC4R and FTO polymorphisms on dyslipidemia in Korean patients with schizophrenia who are taking clozapine
Shi Hyun Kang, Hye Ree Han, Jong‐Il Lee, Rakesh Karmacharya, Hong Jin Jeon, Sungwon Roh
SJR Q1Psychiatry Research
Psychiatry and Mental healthMedicine
14
Article|3 citations·2022
Effects of Chronic Diseases on All-Cause Mortality in People with Mental Illness: A Retrospective Cohort Study Using the Korean National Health Insurance Service-Health Screening
Sujin Son, Yun Jin Kim, Seok Hyeon Kim, Johanna Inhyang Kim, Sojung Kim, Sungwon Roh
SJR Q2International Journal of Environmental Research and Public HealthOA

The aim of this study was to compare mortality and the prevalence of chronic diseases between people with mental illness and the general population, and to explore which chronic diseases increase the risk of all-cause mortality, especially in people with mental illness. This study assessed data from the 2002–2019 Korean National Health Insurance Service-Health Screening sample cohort. Results revealed that all-cause mortality was higher in people with mental illness compared to people without me

Psychiatry and Mental healthMedicine
15
Review|3 citations·2025
Comparative effectiveness of digital versus face-to-face cognitive behavioral therapy for alcohol use disorder: a systematic review and meta-analysis
Jieun Kim, Jiyeong Kim, Na-Yeon Choi, Sang‐Kyu Lee, Hong Seok Oh, Sungwon Roh
SJR Q1Psychological MedicineOA

Abstract Alcohol use disorder (AUD) is a chronic condition that impairs health and function. Cognitive behavioral therapy (CBT) is an evidence-based treatment traditionally delivered face-to-face. Recently, digital CBT delivered online has gained prominence because of access barriers and user preferences. Although many digital CBT studies have emerged, few systematic reviews have directly compared digital and face-to-face CBT in adults with AUD. This systematic review and meta-analysis aimed to

Applied PsychologyPsychology

Research Areas

Psychiatry and Mental healthClinical PsychologyMolecular BiologySocial PsychologySociology and Political SciencePhysiology

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