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Sung Yeon Hwang

Sungkyunkwan University · Medicine

About the Lab

Professor Sung Yeon Hwang's research lab specializes in critical care medicine and emergency medicine, with a primary focus on improving outcomes in sepsis and acute respiratory failure. The lab investigates hemodynamic phenotypes in septic shock, including cryptic and overt shock, and evaluates novel biomarkers such as the lactate/albumin ratio for predicting mortality. It also explores the impact of early adjunctive therapies—like vitamin C and thiamine—on ICU delirium and survival. Additionally, the lab conducts research on airway management, particularly endotracheal intubation techniques and first-pass success during cardiopulmonary resuscitation in the emergency department.

sepsiscritical careairway managementlactate/albumin ratiointubation outcomes

Research Overview

Papers
191
Total Citations
2,297
Papers (5y)
80
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
80total
2021
2022
2023
2024
2025
Citations per year (5y)
449total
20212022202320242025

Selected Papers

15
1
Article|230 citations·2016
Neutrophil-to-lymphocyte ratio as a prognostic marker in critically-ill septic patients
Sung Yeon Hwang, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim
SJR Q1The American Journal of Emergency Medicine
EpidemiologyMedicine
2
Article|157 citations·2020
Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study
Sung Yeon Hwang, Seung Mok Ryoo, Jong Eun Park, You Hwan Jo, Dong‐Hyun Jang, Gil Joon Suh, Taegyun Kim, Youn‐Jung Kim, Seonwoo Kim, Hyun Cho, Ik Joon Jo, Sung Phil Chung
SJR Q1Intensive Care MedicineOA
Nutrition and DieteticsNursing
3
Article|131 citations·2018
Prognostic Value of The Lactate/Albumin Ratio for Predicting 28-Day Mortality in Critically ILL Sepsis Patients
Jikyoung Shin, Sung Yeon Hwang, Ik Joon Jo, Won Young Kim, Seung Mok Ryoo, Gu Hyun Kang, Kyuseok Kim, You Hwan Jo, Sung Phil Chung, Young Seon Joo, Jin Ho Beom, Young‐Hoon Yoon
SJR Q1ShockOA

AIM: The aim of this study was to evaluate the clinical utility of the lactate/albumin (L/A) ratio as a predictive factor of 28-day mortality in critically ill sepsis patients. METHODS: This is a retrospective observational study from a prospectively collected multicenter registry of 10 emergency departments (EDs) in teaching hospitals that participated in the Korean Shock Society. It enrolled patients who were 19 years of age or older who had a suspected or confirmed infection and evidence of r

EpidemiologyMedicine
4
Article|117 citations·2017
Low Accuracy of Positive qSOFA Criteria for Predicting 28-Day Mortality in Critically Ill Septic Patients During the Early Period After Emergency Department Presentation
Sung Yeon Hwang, Ik Joon Jo, Se Uk Lee, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim, Tae Gun Shin
SJR Q1Annals of Emergency Medicine
EpidemiologyMedicine
5
Article|62 citations·2015
Comprehensive Interpretation of Central Venous Oxygen Saturation and Blood Lactate Levels During Resuscitation of Patients With Severe Sepsis and Septic Shock in the Emergency Department
Tae Gun Shin, Ik Joon Jo, Sung Yeon Hwang, Kyeongman Jeon, Gee Young Suh, Euna Choe, Young Kun Lee, Tae Rim Lee, Won Chul, Min Seob Sim
SJR Q1Shock

Oxygenation category, as represented by initial Scvo2 and lactate levels, was significantly associated with 28-day mortality in patients with severe sepsis or septic shock. Associations between Scvo2 ≥70% and 28-day survival were observed only in patients without severe lactic acidosis.

EpidemiologyMedicine
6
Article|54 citations·2019
N95 filtering facepiece respirators do not reliably afford respiratory protection during chest compression: A simulation study
Sung Yeon Hwang, Hee Yoon, Aerin Yoon, Taerim Kim, Gun Tak Lee, Kwang Yul Jung, Joo Hyun Park, Tae Gun Shin, Won Chul, Min Seob Sim, Seonwoo Kim
SJR Q1The American Journal of Emergency Medicine
Emergency MedicineMedicine
7
Article|22 citations·2014
Association Between Hemodynamic Presentation and Outcome in Sepsis Patients
Sung Yeon Hwang, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Won Chul, Min Seob Sim, Keun Jeong Song, Yeon Kwon Jeong
SJR Q1Shock

We aimed to compare outcomes of sepsis patients according to their hemodynamic presentation: cryptic shock (CS), cryptic to overt shock (COS), and overt shock (OS). We analyzed the sepsis registry for adult patients who presented to the emergency department (ED) of a tertiary hospital and met the criteria for severe sepsis or septic shock between August 2008 and March 2012. We classified the patients as having CS, COS, or OS. "Cryptic shock" was defined as severe sepsis with a lactate level of 4

EpidemiologyMedicine
8
Article|22 citations·2020
Impact of Vitamin C and Thiamine Administration on Delirium-Free Days in Patients with Septic Shock
Jong Eun Park, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Minsu Park, Hojeong Won, Chi Ryang Chung, Sung Yeon Hwang
SJR Q1Journal of Clinical MedicineOA

Sepsis is a common cause of delirium in the intensive care unit (ICU). Recently, vitamin C and thiamine administration has been gaining interest as a potential adjunct therapy for sepsis. We investigated the impact of early vitamin C and thiamine administration on ICU delirium-free days among critically ill patients in septic shock. We performed a single-center, retrospective study of patients who visited the emergency department (ED) from January 2017 to July 2018. We categorized patients into

Critical Care and Intensive Care MedicineMedicine
9
Article|21 citations·2019
C-MAC Video Laryngoscope versus Conventional Direct Laryngoscopy for Endotracheal Intubation During Cardiopulmonary Resuscitation
Byeong Chul Min, Jong Eun Park, Gun Tak Lee, Tae Rim Kim, Hee Yoon, Won Chul Cha, Tae Gun Shin, Keun Jeong Song, Minsu Park, Heewon Han, Sung Yeon Hwang
SJR Q2MedicinaOA

Background and objectives: To compare the first pass success (FPS) rate of the C-MAC video laryngoscope (C-MAC) and conventional Macintosh-type direct laryngoscopy (DL) during cardiopulmonary resuscitation (CPR) in the emergency department (ED). Materials and Methods: This study was a single-center, retrospective study conducted from April 2014 to July 2018. Patients were categorized into either the C-MAC or DL group, according to the device used on the first endotracheal intubation (ETI) attemp

Emergency MedicineMedicine
10
Article|18 citations·2018
Quality Improvement Program Outcomes for Endotracheal Intubation in the Emergency Department
Sung Yeon Hwang, Joo Hyun Park, Hee Yoon, Won Chul Cha, Ik Joon Jo, Min Seob Sim, Keun Jeong Song, Hyo Jung Woo, Sung Geun Jeong, Tae Gun Shin
SJR Q1Journal of Patient Safety

OBJECTIVES: We describe our 3-year experience with endotracheal intubation (ETI) outcomes during a multidisciplinary emergency department (ED)-based quality improvement (QI) program. METHODS: This was a single-center, observational study taking place during a QI program. We used a registry for airway management performed in the ED from April 2014 to February 2017. The QI program focused on procedural standardization, airway management education, and comprehensive preparation of airway equipment.

Anesthesiology and Pain MedicineMedicine
11
Article|16 citations·2019
Delayed Antibiotic Therapy and Organ Dysfunction in Critically Ill Septic Patients in the Emergency Department
Sung Yeon Hwang, Jikyoung Shin, Ik Joon Jo, Jong Eun Park, Hee Yoon, Won Chul Cha, Min Seob Sim, Tae Gun Shin
SJR Q1Journal of Clinical MedicineOA

BACKGROUND: We investigated the effect of antibiotic timing on outcomes based on changes in surrogate markers of organ failure, including platelet, serum bilirubin, serum creatinine levels, and the PaO₂/FiO₂ (P/F) ratio. METHODS: This was a single-center, retrospective observational study of critically ill septic patients who presented to the emergency department (ED). The study period extended from August 2008 to September 2016. The primary outcomes included changes in platelet, serum bilirubin

EpidemiologyMedicine
12
Article|14 citations·2022
Defining the learning curve for endotracheal intubation in the emergency department
Gun Tak Lee, Jong Eun Park, Sook‐Young Woo, Tae Gun Shin, Daun Jeong, Taerim Kim, Se Uk Lee, Hee Yoon, Sung Yeon Hwang
SJR Q1Scientific ReportsOA

To determine the minimum number of endotracheal intubation (ETI) attempts necessary for a novice emergency medicine (EM) trainee to become proficient with this procedure. This single-center study retrospectively analyzed data obtained from the institutional airway registry during the period from April 2014 to March 2021. All ETI attempts made by EM trainees starting their residency programs between 2014 and 2018 were evaluated. We used a first attempt success (FAS) rate of 85% as a proxy for ETI

Anesthesiology and Pain MedicineMedicine
13
Article|11 citations·2023
Prognostic Performance of Sequential Organ Failure Assessment, Acute Physiology and Chronic Health Evaluation III, and Simplified Acute Physiology Score II Scores in Patients with Suspected Infection According to Intensive Care Unit Type
Sung Yeon Hwang, In‐Kyu Kim, Daun Jeong, Jong-Eun Park, Gun Tak Lee, Junsang Yoo, Kihwan Choi, Tae Gun Shin, Kyuseok Kim
SJR Q1Journal of Clinical MedicineOA

We investigated the prognostic performance of scoring systems by the intensive care unit (ICU) type. This was a retrospective observational study using data from the Marketplace for Medical Information in the Intensive Care IV database. The primary outcome was in-hospital mortality. We obtained Sequential Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation (APACHE) III, and Simplified Acute Physiology Score (SAPS) II scores in each ICU type. Prognostic performance was

EpidemiologyMedicine
14
Article|11 citations·2021
Impact of Personal Protective Equipment on Out-of-Hospital Cardiac Arrest Resuscitation in Coronavirus Pandemic
Hyeyoung Ko, Jong-Eun Park, Daun Jeong, Tae Gun Shin, Min-Seob Sim, Ik-Joon Jo, Gun Tak Lee, Sung Yeon Hwang
SJR Q2MedicinaOA

Background and Objectives: This retrospective study evaluated the clinical impact of enhanced personal protective equipment (PPE) on the clinical outcomes in patients with out-of-hospital cardiac arrest. Moreover, by focusing on the use of a powered air-purifying respirator (PAPR), we investigated the medical personnel’s perceptions of wearing PAPR during cardiopulmonary resuscitation. Materials and Methods: According to the arrival time at the emergency department, the patients were categorized

Pulmonary and Respiratory MedicineMedicine
15
Article|10 citations·2018
Usefulness of C-MAC video laryngoscope in direct laryngoscopy training in the emergency department: A propensity score matching analysis
Sung Yeon Hwang, Se Uk Lee, Tae Rim Lee, Hee Yoon, Joo Hyun Park, Won Chul, Min Seob Sim, Ik Joon Jo, Keun Jeong Song, Seonwoo Kim, Sun‐Young Baek, Tae Gun Shin
SJR Q1PLoS ONEOA

Our study suggests that the C-MAC could be useful for training residents in the direct laryngoscopy while ensuring patient safety in the emergency department.

Anesthesiology and Pain MedicineMedicine

Research Areas

EpidemiologyEmergency MedicineCardiology and Cardiovascular MedicineCritical Care and Intensive Care MedicinePulmonary and Respiratory MedicineAnesthesiology and Pain Medicine

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