Sung Yung Lim

The aim of this study was done to assess the association of lung function with insulin resistance (IR), systemic inflammation, and metabolic syndrome (MetS). In 9,581 apparently healthy non-smoking male adults, pulmonary function, fasting glucose, insulin, lipid profiles and serum high-sensitivity C-reactive protein (hs-CRP) levels were measured, and homeostatic model assessment (HOMA) was used to assess IR. The presence of MetS was defined according to the AHA/NHLBI criteria. The prevalence of

The aim of this study was done to assess the association of lung function with insulin resistance (IR), systemic inflammation, and metabolic syndrome (MetS). In 9,581 apparently healthy non-smoking male adults, pulmonary function, fasting glucose, insulin, lipid profiles and serum high-sensitivity C-reactive protein (hs-CRP) levels were measured, and homeostatic model assessment (HOMA) was used to assess IR. The presence of MetS was defined according to the AHA/NHLBI criteria. The prevalence of

MetS is more prevalent in women with early COPD. MetS increased the frequency of exacerbations and the medical costs in women with early COPD.

This real-time PCR assay provides a useful tool for the rapid differentiation of most clinically important Mycobacterium species.

Impaired lung function is a risk factor for cardiovascular (CV) events. However, it has not been well established whether FVC reduction even within normal range is associated with cardiovascular disease (CVD) risk and whether reduced FVC is an independent relationship of CVD irrespective of metabolic syndrome. Thus, we aimed to explore the relationship between FVC and CV-event risk using the FRS beyond the presence of metabolic syndrome or abdominal obesity in a representative Korean population

Higher baseline hsCRP is associated with an increased risk to develop COPD in ever smokers but not in never smokers.

The computed tomography-determined EI has a complex association with components of metabolic syndrome that is associated with increased prevalence of hypertension but decreased prevalence of high TGs, whereas FEV1 (% pred) has an inverse association with metabolic syndrome and most of its components with consistent direction.

Introduction Acute exacerbation (AE) of COPD (AECOPD) is an event that is characterized by episode of acute worsening of the patients respiratory symptoms, particularly dyspnea, cough and sputum production beyond the normal daily variation leads to additional therapy.1 An AECOPD can impact the natural course of COPD in the following ways including worsening of quality of life, deterioration of symptoms and lung function (requiring a few weeks to recover), acceleration of decline of lung function

Background Matrix metalloproteinases(MMP) are essential enzymes for tumor invasion and metastasis. Among the MMP family, elevated MMP-9 and stromelysin-3(STR-3) expression have been reported to be poor prognostic factors in lung cancer patients. To evaluate the possibility of a molecular diagnosis of lung cancer using peripheral blood, the mRNA expression level of MMP-9 and STR-3 was measured using a reverse transcriptase-polymerase chain reaction(RT-PCR) in patients with lung cancer. Methods Ni

<b>Background:</b> The age-dependent increase of COPD prevalence suggests an intimate relationship between the process of aging and the development of COPD. Although it remains incompletely understood how the aging process and COPD are interrelated, some previous studies reported the role of telomere length shortening. We aimed to investigate the association between telomere length and COPD as well as its correlation with CT-measured emphysema severity. <b>Method:</b> We measured telomere length

<b><i>Background:</i></b> Previous cross-sectional studies have shown that low muscle mass is associated with albuminuria in the general population. However, the longitudinal association of low muscle mass with the development of albuminuria is not well known at this time. <b><i>Methods:</i></b> We evaluated 48,101 individuals without chronic kidney disease (CKD) who underwent 2 health check-ups in 2012 and 2016. Participants’ skeletal muscle masses were measured using a bioelectrical impedance

Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined as an acute aggravation of the patient's respiratory symptoms, particularly cough, sputum production, and dyspnea, which requires a change of medication. COPD exacerbation leads to an accelerated decline in lung function, poorer health status, and is the main cause of hospital admission and death in patients with COPD. A majority of COPD exacerbations are triggered by respiratory infection. The Management of acute exac

<b>Background:</b> Increasing evidence indicates that chronic obstructive pulmonary disease (COPD) is associated with systemic inflammation. Systemic inflammatory markers, such as C-reactive protein (CRP), are elevated in patients with COPD. We aimed to test the hypothesis that elevated baseline serum CRP level is causally associated with the risk of developing COPD in healthy individuals. <b>Methods:</b> We analyzed 47, 034 participants out of 226,750 Korean adults from the Kangbuk Samsung Heal