Skip to main content

Sunggon Kim

Korea University · Medicine

About the Lab

Professor Sunggon Kim's research lab focuses on metabolic and cardiovascular health, with a strong emphasis on adiposity assessment, insulin resistance, and non-alcoholic fatty liver disease (NAFLD) in diverse population groups. The lab investigates novel anthropometric indices such as the weight-adjusted-waist index (WWI) to improve risk prediction for cardiometabolic diseases, while also exploring the role of adipokines like RBP4 in metabolic dysfunction. Longitudinal studies in Korean populations help elucidate the progression and determinants of NAFLD, particularly in nonobese individuals, and examine paradoxical associations such as the obesity paradox in chronic disease and aging. The lab integrates epidemiological, clinical, and biochemical approaches to identify early biomarkers and risk factors for cardiovascular and metabolic complications.

adiposity assessmentNAFLDcardiometabolic riskobesity paradoxRBP4

Research Overview

Papers
456
Total Citations
12,504
Papers (5y)
73
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
73total
2022
2023
2024
2025
2026
Citations per year (5y)
889total
20222023202420252026

Selected Papers

15
1
Article|549 citations·2018
A novel adiposity index as an integrated predictor of cardiometabolic disease morbidity and mortality
Yousung Park, Nam Hoon Kim, Tae Yeon Kwon, Sin Gon Kim
SJR Q1Scientific ReportsOA

We propose a new anthropometric index, weight-adjusted-waist index (WWI), to assess adiposity by standardizing waist circumference (WC) for weight. WWI, calculated as WC (cm) divided by the square root of weight (kg) (cm/√kg), was measured from 465,629 subjects in the Korean nationwide cohort (2008-2013). Cox regression analysis was used to compare WWI with BMI, WC, waist-to-height ratio (WHtR), and a body shape index (ABSI) for cardiometabolic morbidity and mortality risk in diagnostic and prog

Cardiology and Cardiovascular MedicineMedicine
2
Article|105 citations·2015
Body Mass Index and Mortality in the General Population and in Subjects with Chronic Disease in Korea: A Nationwide Cohort Study (2002-2010)
Nam Hoon Kim, Juneyoung Lee, Tae‐Joon Kim, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Rodica Pop‐Busui, Yousung Park, Sin Gon Kim
SJR Q1PLoS ONEOA

Moderate obesity was associated more strongly with a lower risk of mortality than with normal, underweight, and overweight groups in the general population of South Korea. This obesity paradox was prominent in not only the elderly but also individuals with chronic disease.

Pediatrics, Perinatology and Child HealthMedicine
3
Article|100 citations·2007
Serum retinol‐binding protein 4 levels are elevated in non‐alcoholic fatty liver disease
Ji A Seo, Nan Hee Kim, S. Y. Park, H. Y. Kim, Ohk‐Hyun Ryu, K. W. Lee, Juneyoung Lee, D. L. Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim
SJR Q2Clinical EndocrinologyOA

OBJECTIVE: Retinol-binding protein 4 (RBP4) is a recently identified adipokine that is elevated in the serum in several insulin-resistant states. We investigated the relationship between non-alcoholic fatty liver disease (NAFLD) and serum RBP4 in nondiabetic adults. METHODS: One hundred and fifty-nine nondiabetic, non-alcoholic subjects (95 males and 64 females) participated in this study. Division of subjects into a NAFLD group (n = 73; 45 males and 28 females) or a normal group (n = 86; 50 mal

Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
Article|81 citations·2014
Association of metabolically abnormal but normal weight (MANW) and metabolically healthy but obese (MHO) individuals with arterial stiffness and carotid atherosclerosis
Hye Jin Yoo, Soon Young Hwang, Ho Cheol Hong, Hae Yoon Choi, Ji A Seo, Sin Gon Kim, Nan Hee Kim, Dong Seop Choi, Sei Hyun Baik, Kyung Mook Choi
SJR Q1Atherosclerosis
Cardiology and Cardiovascular MedicineMedicine
5
Article|80 citations·2014
Clinical and metabolic factors associated with development and regression of nonalcoholic fatty liver disease in nonobese subjects
Nam Hoon Kim, Joo Hyung Kim, Yoon Jung Kim, Hye Jin Yoo, Hee Young Kim, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi, Sin Gon Kim
SJR Q1Liver International

BACKGROUND & AIMS: The course of NAFLD (nonalcoholic fatty liver disease) and associated factors in nonobese subjects are not well established. We investigated contributing factors for the development and regression of NAFLD in nonobese Koreans, and whether they would differ from those of obese subjects. METHODS: Two thousand three hundred and seven adults aged over 18 years participated in this longitudinal observational study. The mean duration of follow-up was 28.7 (±13.2) months. The partici

EpidemiologyMedicine
6
Article|79 citations·2014
Efficacy and Safety of Lobeglitazone Monotherapy in Patients with Type 2 Diabetes Mellitus over 24-Weeks: A Multicenter, Randomized, Double-Blind, Parallel-Group, Placebo Controlled Trial
Sin Gon Kim, Doo Man Kim, Jeong‐Taek Woo, Hak Chul Jang, Choon Hee Chung, Kyung Soo Ko, Jeong Hyun Park, Yong Soo Park, Sang Jin Kim, Dong Seop Choi
SJR Q1PLoS ONEOA

Clinicaltrials.gov NCT01001611.

Endocrinology, Diabetes and MetabolismMedicine
7
Article|63 citations·2020
Prevalence and complications of nonsurgical hypoparathyroidism in Korea: A nationwide cohort study
Se Hwa Kim, Yumie Rhee, Yoo Mee Kim, Young Jun Won, Jung Hyun Noh, Hyemi Moon, Juneyoung Lee, Sin Gon Kim
SJR Q1PLoS ONEOA

The prevalence of nonsurgical hypoparathyroidism was very low in Korea but was associated with a higher risk of incident cardiovascular disease and vertebral fracture as well as known complications including renal disease, seizure, and cataract.

SurgeryMedicine
8
Article|48 citations·2006
Effect of rosiglitazone on plasma adiponectin levels and arterial stiffness in subjects with prediabetes or non-diabetic metabolic syndrome
Sin Gon Kim, Ohk Hyun Ryu, Hee Young Kim, Kye Won Lee, Ji A Seo, Nan Hee Kim, Kyung Mook Choi, Juneyoung Lee, Sei Hyun Baik, Yunjung Cho
SJR Q1European Journal of Endocrinology

OBJECTIVE: Thiazolidinediones have favorable influences on surrogate markers of atherosclerosis such as adiponectin, and arterial stiffness in diabetic patients. However, it is not well known whether these beneficial effects occur in subjects without diabetes, such as prediabetes or the non-diabetic metabolic syndrome (MetS). The present study was therefore designed to evaluate the effectiveness of the insulin-sensitizing agent rosiglitazone on circulating adipocytokine levels and brachial-ankle

EpidemiologyMedicine
9
Article|47 citations·2012
North Korean refugee health in South Korea (NORNS) study: study design and methods
Yo Han Lee, Won Jin Lee, Yun Jeong Kim, Myong Jin Cho, Joo Hyung Kim, Yun Jeong Lee, Hee Young Kim, Dong Seop Choi, Sin Gon Kim, Courtland Robinson
SJR Q1BMC Public HealthOA

BACKGROUND: Understanding the health status of North Korean refugees (NKRs), and changes in health during the resettlement process, is important from both the humanitarian standpoint and the scientific perspective. The NOrth Korean Refugee health iN South Korea (NORNS) study aims to document the health status and health determinants of North Korean refugees, to observe various health outcomes as they occur while adapting to the westernized lifestyle of South Korea, and to explain the mechanisms

Sociology and Political ScienceSocial Sciences
10
Article|45 citations·2017
Trends in socioeconomic inequalities in five major risk factors for cardiovascular disease in the Korean population: a cross-sectional study using data from the Korea National Health and Nutrition Examination Survey, 2001–2014
Yoonjung Kim, Ji Sung Lee, Ji Sung Lee, Juri Park, Dong Seop Choi, Doo Man Kim, Kee‐Hyoung Lee, Hoyeon Kim, Sin Gon Kim, Juneyoung Lee, Juneyoung Lee
SJR Q1BMJ OpenOA

OBJECTIVES: To examine trends in socioeconomic inequalities in major cardiovascular disease (CVD) risk factors among the Korean population. DESIGN: Cross-sectional study. SETTING: A nationally representative population survey database. PARTICIPANTS: A total of 42 725 Koreans, aged 25-64 years, who participated in the Korean National Health and Nutrition Examination Survey (KNHANES) II (2001) to VI (2013-2014). MAIN OUTCOME MEASURES: Trends in socioeconomic inequalities in five major CVD risk fac

HealthSocial Sciences
11
Article|45 citations·2008
The Present State of Diabetes Mellitus in Korea
Sin Gon Kim, Dong Seop Choi
SJR Q4Journal of Korean Medical AssociationOA

Focused Issue of This Month (social epidemic) . 70 1.5% (1), 10% (2, 3).

General Health ProfessionsHealth Professions
12
Article|43 citations·2016
Delay of insulin initiation in patients with type 2 diabetes mellitus inadequately controlled with oral hypoglycemic agents (analysis of patient‐ and physician‐related factors): A prospective observational DIPP‐FACTOR study in Korea
Sin Gon Kim, Nam Hoon Kim, Bon Jeong Ku, Ho Sang Shon, Doo Man Kim, Tae Sun Park, Yong‐Seong Kim, In Joo Kim, Yunjung Cho
SJR Q1Journal of Diabetes InvestigationOA

AIMS/INTRODUCTION: To assess the time to initiation of insulin therapy, and concurrently investigate both patient- and physician-related factors associated with delaying insulin therapy in Korean patients with type 2 diabetes uncontrolled by oral hypoglycemic agents (OHAs). MATERIALS AND METHODS: This prospective, observational disease registry study was carried out across 69 centers in Korea. Type 2 diabetes patients who had received two or more OHAs within the past 5 years, had a glycated hemo

Endocrinology, Diabetes and MetabolismMedicine
13
Article|43 citations·2016
Effect ofRubus OccidentalisExtract on Metabolic Parameters in Subjects with Prediabetes: A Proof-of-concept, Randomized, Double-blind, Placebo-controlled Clinical Trial
Jee Hyun An, Dong-Lim Kim, Taebum Lee, Kyeong Jin Kim, Sun Hwa Kim, Sun Hwa Kim, Nam Hoon Kim, Hee Young Kim, Dong Seop Choi, Sin Gon Kim, Sin Gon Kim
SJR Q1Phytotherapy Research

Rubus occidentalis (RO) has beneficial effects on glucose and lipid profiles in vitro. The aim of the study was to investigate RO extract effect on metabolic parameters in prediabetic patients, adopting a 12-week, randomized, double-blind, placebo-controlled trial. Forty-four patients (age 59.0 ± 8.2 years, 70.5% females, HbA1c 5.8 ± 0.4%) were divided into placebo (n = 13), low-dose RO extract (LRE; n = 14), or high-dose RO extract (HRE; n = 17) groups. Either 900 or 1800 mg per day of RO extra

BiochemistryMedicine
14
Article|40 citations·2018
Dipeptidyl peptidase-4 inhibitor use and risk of diabetic retinopathy: A population-based study
Nan Hee Kim, Jong‐Il Choi, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Juneyoung Lee, Sin Gon Kim
SJR Q1Diabetes & Metabolism
Endocrinology, Diabetes and MetabolismMedicine
15
Article|38 citations·2005
Relationship between serum adiponectin concentration, pulse wave velocity and nonalcoholic fatty liver disease
Sin Gon Kim, H. Y. Kim, Ji A Seo, K W Lee, Joung-Hwan Oh, Nan Hee Kim, Kyung Mook Choi, Sei Hyun Baik, Dong Seop Choi
SJR Q1European Journal of EndocrinologyOA

OBJECTIVES: We aimed to investigate the relationship between nonalcoholic fatty liver disease (NAFLD), serum adiponectin concentration and brachial-ankle pulse wave velocity (baPWV) as a risk marker for atherosclerosis. METHODS: A total of 213 nonalcoholic subjects (67 males, 146 females) participated in this study. Division of subjects into the NAFLD group or the normal group was based on the existence of fatty liver detected by sonography. RESULTS: Serum adiponectin levels in the NAFLD group w

EpidemiologyMedicine

Research Areas

Endocrinology, Diabetes and MetabolismAerospace EngineeringEpidemiologyPhysiologySurgeryCardiology and Cardiovascular Medicine

Dive deeper into Sunggon Kim's research on Nubint

Open this lab's papers in the app to read with AI, summarize, and cite in your writing.