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Sungho Shin

Yonsei University · Medicine

About the Lab

Professor Sungho Shin's research lab focuses on clinical and translational research in audiology, otology, and regenerative medicine, with a strong emphasis on gait analysis, hearing loss epidemiology, and otologic surgical outcomes. The lab investigates the validity and reliability of advanced gait assessment systems, explores molecular pathways for hair regeneration (e.g., Wnt/β-catenin activation), and evaluates treatment strategies for middle ear disorders such as cholesteatoma. Their work contributes to evidence-based clinical decision-making and public health policy through population-based hearing studies and surgical outcome analyses.

gait analysishearing losscholesteatomaWnt pathwayotological surgery

Research Overview

Papers
108
Total Citations
1,273
Papers (5y)
20
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
20total
2021
2022
2023
2024
2025
Citations per year (5y)
67total
20212022202320242025

Selected Papers

15
1
Article|159 citations·2018
Comparison of Surgical Invasiveness Between Microdiscectomy and 3 Different Endoscopic Discectomy Techniques for Lumbar Disc Herniation
Kyung-Chul Choi, Hyeong-Ki Shim, Jin-Sup Hwang, Seung Ho Shin, Dong Chan Lee, Hwan Hui Jung, Hyeon Ah Park, Choon-Keun Park
SJR Q2World Neurosurgery
Pathology and Forensic MedicineMedicine
2
Article|134 citations·2014
Concurrent Validity and Test-retest Reliability of the OPTOGait Photoelectric Cell System for the Assessment of Spatio-temporal Parameters of the Gait of Young Adults
Myung Mo Lee, Chang Ho Song, Kyoung Jin Lee, Sang Woo Jung, Doochul Shin, Seung Ho Shin
Journal of Physical Therapy ScienceOA

[Purpose] The purpose of this study was to investigate the concurrent validity and test-retest reliability of the recently introduced OPTOGait Photoelectric Cell System for the assessment of spatio-temporal parameters of gait. [Subjects] Twenty healthy young adults (mean age = 27.35, SD = 7.4) were asked to walk 3 times on walkway at a comfortable speed. [Methods] Concurrent validity was assessed by comparing data obtained using the OPTOGait and GAITRite systems, and reliability was assessed by

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
3
Article|125 citations·2012
Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells
Soung-Hoon Lee, Juyong Yoon, Seung Ho Shin, Muhamad Zahoor, Hyoung Jun Kim, Phil June Park, Won Seok Park, Do Sik Min, Hyun Yi Kim, Kang Choi
SJR Q1PLoS ONEOA

Our findings indicate that small molecules that activate the Wnt/β-catenin pathway, such as VPA, can potentially be developed as drugs to stimulate hair re-growth.

UrologyMedicine
4
Article|72 citations·2010
Classification of External Auditory Canal Cholesteatoma by Computed Tomography
Seung Ho Shin, Jae Han Shim, Ho-Ki Lee
SJR Q1Clinical and Experimental OtorhinolaryngologyOA

This proposed staging is simple and easily applicable for use when deciding the treatment plan for patients with EACC.

OtorhinolaryngologyMedicine
5
Review|70 citations·2013
Current trends in the management of the complications of chronic otitis media with cholesteatoma
Sampath Chandra Prasad, Seung Ho Shin, Alessandra Russo, Giuseppe Di Trapani, Mario Sanna
SJR Q2Current Opinion in Otolaryngology & Head & Neck Surgery

There is considerable debate in the management of almost every complication of cholesteatoma. Multicentric studies to compare the efficacies of various treatment modalities are the need of the hour to come to definitive conclusions regarding the best treatment options.

OtorhinolaryngologyMedicine
6
Article|48 citations·2019
α-Linolenic acid-enriched butter attenuated high fat diet-induced insulin resistance and inflammation by promoting bioconversion of n-3 PUFA and subsequent oxylipin formation
Rong Fan, Judy Kim, Mikyoung You, David Giraud, Ashley M. Toney, Seung Ho Shin, So‐Youn Kim, Kamil Borkowski, John W. Newman, Soonkyu Chung
SJR Q1The Journal of Nutritional BiochemistryOA
Nutrition and DieteticsNursing
7
Article|46 citations·2016
Age- and Gender-Related Mean Hearing Threshold in a Highly-Screened Population: The Korean National Health and Nutrition Examination Survey 2010–2012
Yun Hwi Park, Seung Ho Shin, Sung Wan Byun, Ju Yeon Kim
SJR Q1PLoS ONEOA

The data from KNHANES 2010-2012 showed gender differences at hearing thresholds of 3 kHz, 4 kHz, and 6 kHz in a highly-screened population. The most significant gender difference in relation to hearing threshold was observed at 4 kHz. The hearing thresholds at all of the tested frequencies worsened with increasing age. The mean hearing thresholds suggested in this study will be useful for the formulation of healthcare-related hearing policies and used as reference data for disability ratings for

Cognitive NeuroscienceNeuroscience
8
Article|17 citations·2006
Wheel-shaped cartilage-perichondrium composite graft for the prevention of retraction pocket development
Seung Ho Shin, Won Sang Lee, Hee Nam Kim, Ho-Ki Lee
SJR Q2Acta Oto-LaryngologicaOA

A retraction pocket was observed in three cases (6.7%). Slight protrusion of partial ossicular replacement prosthesis (PORP) and lateral healing of drum was observed in one case each, and there were two cases of postoperative infection. The number of cases with an air-bone gap (ABG)<20 dB increased from 9 (23%) cases before operation, to 20 cases (51%) after operation. The ABG average statistically decreased from 30.0 dB to 24.0 dB, and the mean air conduction thresholds decreased from a preoper

OtorhinolaryngologyMedicine
9
Article|16 citations·2013
Revision Cochlear Implantation With Different Electrodes Can Cause Incomplete Electrode Insertion and Poor Performance
Seung Ho Shin, Se-Ra Park, Won Sang Lee, Heung Dong Kim, Jae Young Choi
SJR Q1Otology & NeurotologyOA

In this study, full electrode insertion was achieved in all cases where the same type of electrode was used during initial and revision CI. In contrast, we noticed incomplete insertion in 4 of 5 patients who had revision electrodes that differed from initial electrodes. While incomplete electrode insertion does not necessitate poor speech performance, some patients with incomplete electrode insertion certainly experience it. Therefore, electrode selection requires circumspection in revision CI.

Cognitive NeuroscienceNeuroscience
10
Article|16 citations·2022
The Time Course of Monocytes Infiltration After Acoustic Overstimulation
Seung Ho Shin, Jinsei Jung, Haeng Ran Park, Nam Suk Sim, Jae Young Choi, Seong Hoon Bae
SJR Q1Frontiers in Cellular NeuroscienceOA

Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to protect hearing function from injury, including acoustic overstimulation. Cochlea macrophage numbers increase at 3–7 days after acoustic stimulation. However, the exact timing of macrophage infiltration and maturation from inflammatory monocytes is unclear. Furthermore, neutrophils may also be involved in this process. Therefore, in this study, we investigated time-dependent immune cell infiltration, macrophage t

ImmunologyImmunology and Microbiology
11
Article|12 citations·2022
Inflammatory Monocytes Infiltrate the Spiral Ligament and Migrate to the Basilar Membrane After Noise Exposure
Seung Ho Shin, Jee Eun Yoo, Jinsei Jung, Jae Young Choi, Seong Hoon Bae
SJR Q1Clinical and Experimental OtorhinolaryngologyOA

OBJECTIVES: Noise exposure leads to an increase in the macrophage population. This increment is thought to be caused by the transformation of infiltrated monocytes into macrophages rather than by proliferation of the cochlear resident macrophages. However, studies on infiltrated monocytes in the cochlea are scarce. Thus, we aimed to investigate the infiltration of monocytes and their transformation into macrophages after noise exposure. METHODS: In wild-type and CX3CR1+/GFP C57/B6 mice, inflamma

Sensory SystemsNeuroscience
12
Article|8 citations·2014
Effect of gait training with additional weight on balance and gait in stroke patients
Seung Ho Shin, Mi Young Lee
Physical therapy rehabilitation scienceOA

To study the effects of gait training with additional weight and gait training with non-additional weight on balance ability and gait ability in patients with chronic stroke through comparative analysis.

RehabilitationMedicine
13
Article|3 citations·2007
A cochlear schwannoma presenting with sudden hearing loss
Seung Ho Shin, Young‐Myoung Chun, Ho-Ki Lee
SJR Q1European Archives of Oto-Rhino-Laryngology
EpidemiologyMedicine
14
Article|1 citations·2025
Middle Ear Neuroendocrine Tumor With Transient Facial Paralysis
Seung Ho Shin, Eunah Shin, Eun Jin Son
SJR Q2Journal of Craniofacial Surgery

Neuroendocrine tumors originating in the middle ear are rare, and presentation with facial paralysis is extremely uncommon. A 19-year-old woman with a history of transient facial paralysis presented with a right-sided middle ear mass. Surgical exploration of the tympanic cavity was performed using a transcanal endoscopic approach. Histopathologic examination confirmed the diagnosis of a middle ear neuroendocrine tumor. After surgical excision of the tumor, no recurrence or facial paralysis occur

OncologyMedicine
15
Article|0 citations·2021
A Case of Merkel Cell Carcinoma of the External Auditory Canal Skin with Annulus and Tympanic Membrane
Ara Cho, Mi Jang, In Seok Moon, Seung Ho Shin
SJR Q4Korean Journal of Otorhinolaryngology - Head and Neck SurgeryOA

Merkel cell carcinoma is an extremely rare neuroendocrine neoplasm of the external auditory canal (EAC) skin, which requires wide excision and adjuvant radiation due to a high recurrence rate. In this report, we describe a case of Merkel cell carcinoma arising from the EAC which was successfully treated with endoscopic excision. A 32-years-old female patient with a history of papillary thyroid cancer was diagnosed with an EAC tumor incidentally. There was a erythematous papular lesion on the pos

OncologyMedicine

Research Areas

SurgeryEpidemiologyPathology and Forensic MedicineOtorhinolaryngologyOcean EngineeringOncology

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