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Tae-Ju Jeon

Yonsei University · Medicine

About the Lab

Professor Tae-Ju Jeon's research lab specializes in nuclear medicine and molecular imaging, with a focus on advancing diagnostic and therapeutic applications in oncology, cerebrovascular disorders, and metabolic diseases. The lab investigates molecular imaging biomarkers—particularly using 18F-FDG PET/CT and novel radiotracers like [(18)F]Mefway—for early detection, prognosis, and personalized treatment of cancers such as colorectal cancer. It also explores the pathophysiology of conditions like normal-appearing white matter disease, intracranial hypotension due to multiple CSF leaks, and radiation-induced hypothyroidism in differentiated thyroid cancer patients. The lab emphasizes the development of automated, reliable radiofluorination techniques to support clinical translation of new PET tracers.

molecular imagingPET/CTradiotracer developmentoncologycerebrospinal fluid leak

Research Overview

Papers
122
Total Citations
1,397
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2022
2023
2024
2025
2026
Citations per year (5y)
41total
20222023202420252026

Selected Papers

15
1
Article|64 citations·2014
Subclinical vascular inflammation in subjects with normal weight obesity and its association with body Fat: an 18 F-FDG-PET/CT study
Shinae Kang, Chanhee Kyung, Jong Suk Park, Sohee Kim, Seung‐Pyo Lee, Min Kyung Kim, Hye Kyung Kim, Kyung Rae Kim, Tae Joo Jeon, Chul Woo Ahn
SJR Q1Cardiovascular DiabetologyOA

NWO is associated with a higher degree of subclinical vascular inflammation, of which BF is a major contributing factor. These results warrant investigations for subclinical atherosclerosis in NWO patients.

Cardiology and Cardiovascular MedicineMedicine
2
Article|37 citations·2000
Evaluation of cardiac adrenergic neuronal damage in rats with doxorubicin-induced cardiomyopathy using iodine-131 MIBG autoradiography and PGP 9.5 immunohistochemistry
Tae Joo Jeon, Jong Doo Lee, Jong‐Won Ha, Woo Ick Yang, Sang-Ho Cho
SJR Q1European Journal of Nuclear Medicine and Molecular ImagingOA
Cardiology and Cardiovascular MedicineMedicine
3
Article|27 citations·2001
Radionuclide cisternography in spontaneous intracranial hypotension with simultaneous leaks at the cervicothoracic and lumbar levels.
Tae Joo Jeon, Jong Doo Lee, BYUNG IN LEE, Dong‐Ik Kim, Hyung Sik Yoo
SJR Q2Clinical Nuclear Medicine

This case report clearly illustrates defined simultaneous cerebrospinal fluid leaks at the cervicothoracic and upper lumbar areas. A 53-year-old woman without a remarkable medical history was hospitalized for sudden onset of severe headache. The headache lasted more than 1 week and standing or sitting positions exaggerated the symptoms, although it was relieved when the patient was recumbent. Radionuclide cisternography was performed using 150 MBq (4 mCi) Tc-99m DTPA. It revealed two cerebrospin

NeurologyMedicine
4
Article|21 citations·2016
Relationship Between 18F-Fluorodeoxyglucose Uptake and V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Mutation in Colorectal Cancer Patients
Jae‐Hoon Lee, Jeonghyun Kang, Seung Hyuk Baik, Kang Young Lee, Beom Jin Lim, Tae Joo Jeon, Young Hoon Ryu, Seung‐Kook Sohn
SJR Q3MedicineOA

To evaluate clinical values of clinicopathologic and 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT)-related parameters for prediction of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutation in colorectal cancer (CRC) and to investigate their variability depending on C-reactive protein (CRP) levels. In total, 179 CRC patients who underwent PET/CT scans before curative resection and KRAS mutation evaluation following surgery were enrolled

OncologyMedicine
5
Article|14 citations·2014
Mesenteric pseudocyst of the transverse colon: unusual presentation of more common pathology
Seong Eun Park, Tae Joo Jeon, Ji Young Park
SJR Q4BMJ Case ReportsOA

A 72-year-old man presented to the hospital with a cyst in the abdominal cavity as the main finding obtained by abdominal CT. The cyst measured 13.5×9 cm and was located near the proximal wall of the body of the stomach. Endoscopic ultrasonography revealed that, the size of the cyst was 8.6×8.8 cm and that most of it was anechoic. However, partially heterogeneous and hypoechoic solid portions and a septum were detected. This cystic lesion was separated from the stomach wall and pancreas. Surgica

SurgeryMedicine
6
Article|13 citations·2014
Rebound Thymic Hyperplasia Detected by 18 F-FDG PET/CT After Radioactive Iodine Ablation Therapy for Thyroid Cancer
Tae Joo Jeon, Yong Sang Lee, Jae‐Hoon Lee, Hang‐Seok Chang, Young Hoon Ryu
SJR Q1ThyroidOA

RTHP after RIAT showed a strong female predominance, despite the higher administration dose of RAI in male patients. Although the decreased incidence of RTHP after RIAT with age is similar to the pattern of RTHP induced by other causes, the fact that older patients, even sixth decade patients, can present with RTHP after RIAT is noteworthy in the management of DTC.

Endocrinology, Diabetes and MetabolismMedicine
7
Article|10 citations·2013
Optimization of the radiosynthesis of [18F]MEFWAY for imaging brain serotonin 1A receptors by using the GE TracerLab FXFN‐Pro module
Jae Yong Choi, Chul Hoon Kim, Young Hoon Ryu, Young Beom Seo, Phong Truong, Eun Jung Kim, Tae Hyun Choi, JeeHae Kang, Min-Kyung Lee, Dong Goo Kim, Jong Doo Lee, Tae Joo Jeon
SJR Q3Journal of Labelled Compounds and RadiopharmaceuticalsOA

The aim of this study was to develop a highly reliable radiofluorination method for the preparation of N-{2-[4-(2-methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(4-(18) F-fluoromethylcyclohexane)carboxamide ([(18) F]Mefway) by using a fully automated system. The optimal condition is composed of two parts. The extraction system of the trapped F-18 in the anion exchange resin (i.e., quaternary methylamine cartridge) is a complex of Kryptofix 2.2.2. (K222, 4 mg/0.9 mL methanol) and K2 CO3 (1 mg/0

Radiology, Nuclear Medicine and ImagingMedicine
8
Article|9 citations·2014
A Case of Tracheal Metastasis in Colon Cancer
Minkyung Lee, Yu Kyung Lee, Tae Joo Jeon, Seung‐Kook Sohn, Young Hoon Ryu
SJR Q2Clinical Nuclear Medicine

A 44-year-old female patient received proctocolectomy and chemotherapy for a diagnosis of colon cancer 10 years previously and presented here with new onset of cough for 2 months and a progressive increase of her serum CA19-9 level. F-FDG PET/CT imaging revealed a hypermetabolic lesion within the trachea. Immunostaining confirmed that this lesion was a metastatic adenocarcinoma that originated from the patient's initial colon cancer. F-FDG PET/CT enabled localization of unusual endotracheal meta

Pulmonary and Respiratory MedicineMedicine
9
Article|7 citations·2018
The 18F-FDG PET/CT response to radiotherapy for patients with spinal metastasis correlated with the clinical outcomes
Jinhyun Choi, Jun Won Kim, Tae Joo Jeon, Ik Jae Lee
SJR Q1PLoS ONEOA

RT is an effective treatment for patients with spinal metastases, and there were significant changes in PET parameters compared with baseline. The metabolic response measured by SUV and TLG changes in FDG-PET/CT correlated with the clinical outcomes, especially with shorter PFS in patients who had higher residual maximum SUV after treatment.

SurgeryMedicine
10
Article|7 citations·2018
Use of 18F-sodium fluoride bone PET for disability evaluation in ankle trauma: a pilot study
Tae Joo Jeon, Sung Jun Kim, Jin‐Young Park, Jinyoung Park, Eugene Y. Roh, Jung Hyun Park, Eugene Y. Roh
SJR Q2BMC Medical ImagingOA

BACKGROUND: There are no objective and accurate rating tools for permanent impairment of traumatized ankles. The purpose of this study is to assess the role of 18F-Sodium fluoride (18F-NaF) positron emission tomography-computed tomography (PET/CT) bone scans in evaluating patients with limited ankle range of motion (ROM) after trauma. METHODS: 18F-NaF PET/CT was performed in 121 patients (75 men, 46 women; mean age: 45.8) who had ROM < 70% of normal after trauma affecting ankles. Metabolic targe

Orthopedics and Sports MedicineMedicine
11
Article|5 citations·2014
131I Uptake in Intraosseous Hemangioma of the Skull
Minkyung Lee, Yu Kyung Lee, Tae Joo Jeon, Cheong Soo Park, Young Hoon Ryu
SJR Q2Clinical Nuclear Medicine

We report a case of unusual 131I uptake in the skull in a patient who received total thyroidectomy and cervical lymph node dissection for papillary thyroid carcinoma. This uptake mimicked a bone metastasis on posttherapeutic 131I whole-body scan. The lesion was further evaluated by 131I SPECT/CT and MRI, and it was identified as intraosseous hemangioma. For the prevention of unnecessary repeat ablation therapies and physicians' confusion, the nuclear medicine physicians have to consider the 131I

SurgeryMedicine
12
Article|2 citations·2008
^18F-FDG-PET/CT in Prostate Cancer
Tae Joo Jeon
SJR Q2Nuclear Medicine and Molecular Imaging
Pulmonary and Respiratory MedicineMedicine
13
Article|2 citations·2014
Urachal cancer with direct caecal invasion: differential diagnosis from primary colon cancer
Ji Young Park, Tae Joo Jeon, Mi Jin Ryu, Won Chang Shin
SJR Q4BMJ Case Reports

A 56-year-old man who had a history of repeated previous treatment for cystitis was admitted with abdominal distension, dysuria, pollakiuria, nocturia and sensation of urine retention after emptying the bladder. A CT scan showed a 10 cm irregularly shaped soft tissue mass abutting the anterosuperior aspect of the urinary bladder with wall thickening and a soft tissue component in the caecum. Colonoscopy revealed an encircling huge fungating mass on the caecum. The tumour was removed surgically.

SurgeryMedicine
14
Article|1 citations·2009
^18 F-Fluoride-PET in Skeletal Imaging
Tae Joo Jeon
SJR Q2Nuclear Medicine and Molecular Imaging
Radiology, Nuclear Medicine and ImagingMedicine
15
Article|0 citations·2002
Increase of Tc-99m RBC SPECT Sensitivity for Small Liver Hemangioma using Ordered Subset Expectation Maximization Technique
Tae Joo Jeon, Jung Kyun Bong, Hee Joung Kim, Myeong‐Jin Kim, Jong Doo Lee
SJR Q2Nuclear Medicine and Molecular Imaging
Pulmonary and Respiratory MedicineMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingPulmonary and Respiratory MedicineOncologySurgeryCardiology and Cardiovascular MedicineGastroenterology

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