Ui-Won Jeong
Yonsei University · Dentistry
About the Lab
Professor Ui-Won Jeong's research lab specializes in oral and maxillofacial implantology, focusing on improving clinical outcomes through advanced biomaterials, minimally invasive drug delivery systems, and innovative surgical techniques. Key research directions include the development of dissolving microneedles for efficient local anesthetic delivery, the evaluation of implant surface decontamination protocols to maintain long-term osseointegration, and the assessment of alveolar ridge preservation techniques to minimize post-extraction bone loss. The lab also investigates the performance and longevity of narrow-diameter implants and utilizes advanced imaging technologies to optimize surgical planning and tissue response prediction.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15BACKGROUND: Periodontal plastic surgery is used to fulfill the esthetic and functional demands of patients. The palatal masticatory mucosa is the main donor site for connective tissue, and the thickness of the graft tissue obtained is an important factor for the success of this technique. The aim of this study was to measure the thickness of masticatory mucosa in the posterior palatal area using computerized tomography (CT). METHODS: The thickness measurements were performed on the images of 100
OBJECTIVES: To test whether or not alveolar ridge preservation reduces vertical changes in the posterior maxilla compared to spontaneous healing following tooth extraction. MATERIALS AND METHODS: Forty subjects requiring extraction of maxillary posterior teeth with root apices protruding into the maxillary sinus floor were consecutively enrolled. Patients were randomly assigned to either one of two surgical interventions: an alveolar ridge preservation procedure using collagenated bovine bone mi
Lidocaine is a local anesthetic agent used in the form of injection and topical cream. However, these formulation types have limitations of being either painful or slow-acting, thereby hindering effective and complete clinical performance of lidocaine. Dissolving microneedles (DMNs) are used to overcome these limitations owing to their fast onset time and minimally invasive administration methods. Using hyaluronic acid and lidocaine to produce the drug solution, a lidocaine HCl encapsulated DMN
OBJECTIVE: To evaluate in vitro the changes in implant surface topography and roughness of commercial implants after instrumentation with five decontamination protocols. MATERIAL AND METHODS: Seventy-two titanium implants with a sandblasted and acid-etched (SLA) surface were placed 5 mm supra-crestally. Five groups of twelve implants were instrumented with the following protocols: a metal scaler tip (SCAL), a thermoplastic scaler tip (PEEK), a round titanium brush (RBRU), a tufted brush with tit
OBJECTIVE: The objectives of this study were to analyze retrospectively the long-term survival and success rates of Narrow implants (NIs) placed with various implant systems, and the association with biological and technical complications. MATERIAL AND METHODS: In total, 338 patients (men = 45.6%, women = 54.4%) who received 541 NIs (≤3.5 mm in diameter) for fixed prostheses were enrolled in this retrospective study. The mean marginal bone level (MMBL) change was calculated. Life table analysis
These HA-coated implants exhibited increased roughness, crystallinity, and wettability when compared with RBM implants.
OBJECTIVES: The purpose of this pilot study was to determine the osteoinductive effect of absorbable collagen sponge (ACS) loaded with Escherichia coli-expressed recombinant human bone morphogenetic protein 2 (ErhBMP-2) and evaluate structural stability of ACS in a standardized rabbit sinus model. MATERIAL AND METHODS: The maxillary sinuses were prepared bilaterally in six male white rabbits. The windows were prepared using a 6 mm trephine bur, and circular bony windows were carefully removed. F
BACKGROUND: Beta tricalcium phosphate (beta-TCP) has been developed as one of the carriers of recombinant human bone morphogenetic protein (rhBMP). However, it is not known whether the particle size of beta-TCP is related to its resorption rate and the degree of bone formation. The purpose of this study was to evaluate the effect of using beta-TCP with different particle sizes on the ability of rhBMP-4 to enhance bone formation in the rat calvarial defect model. METHODS: Calvarial, 8-mm-diameter
AIM: The objective of this study was to determine the efficacy of bone morphogenetic protein 2 (BMP-2) in a bovine hydroxyapatite/collagen (BHC) carrier to augment bone formation in a canine nasal sinus model. METHODS: Eight mongrel dogs, approximately 12 months old and 30 kg in weight were used. Following preparation of bilateral sinus access windows, BHC alone (control) or loaded with E. coli-derived BMP-2 at 0.1 mg/ml was implanted in four animals, and BHC loaded with E. coli-derived BMP-2 at
OBJECTIVES: To evaluate the effect of vertical and periosteal-releasing incisions (PRI) on the extension of the buccal flap in a trapezoidal flap design. MATERIAL AND METHODS: Thirty patients scheduled for implant surgery accompanied by bone augmentation were recruited. The amount of flap extension pulled with a minimal tension of 5 g using a dynamometer was measured before and after the first and the second vertical incisions (VI) and PRI. The results were compared based on gender, surgical sit
PURPOSE: The objective of this study was to determine the effectiveness of collagenated biphasic calcium phosphate (CBCP) as a carrier for bone morphogenetic protein-2 (BMP-2) at the early stage of healing in rabbit sinus. MATERIAL AND METHODS: In 16 rabbits, BMP-2-loaded CBCP was grafted into one sinus (the BMP group) and saline-soaked CBCP was grafted into another sinus (the CTL group). The groups were assigned randomly. After 2 weeks (n = 8) or 4 weeks (n = 8), radiographic and histological a
OBJECTIVES: The aim of this retrospective study was to determine the clinical and the radiographic outcomes of dental implants placed in elderly people older than 65 years. MATERIALS AND METHODS: In total, 902 implants in 346 patients (age: 65-89 years) were followed up for 2-17 years following the implant surgery. The survival rate of these implants was recorded and analyzed. Changes in marginal bone levels were also analyzed in serial radiographs, and Cox regression analysis for implant loss w
BACKGROUND: The palatal area has been the major donor site for obtaining connective tissue for root-coverage procedures. This study evaluated the long-term outcome of using a gingival cuff from the maxillary tuberosity area as a donor site for root coverage procedures. METHODS: Case 1: A 26-year-old female patient complaining of tooth hypersensitivity and gingival recession on the maxillary left canine was treated with root coverage using a pouch technique. A connective tissue graft was obtained
The purpose of this study was to evaluate the effects of a chitosan membrane coated with polylactic and polyglycolic acid (PLGA) on bone regeneration in a rat calvarial defect. Surgical implantation of chitosan membranes resulted in enhanced local bone formation at both 2 and 8 weeks. In conclusion, the chitosan membrane coated with PLGA had a significant potential to induce bone formation in the rat calvarial defect model. Within the selected PLGA dose range and observation intervals, there app
AIM: To test whether soft-type block bone substitute used for guided bone regeneration (GBR) of peri-implant defects leads to a different dimension of the augmented hard tissue than particulate bone substitute. MATERIALS AND METHODS: In 40 patients, 40 two-piece dental implants were placed >2 months after tooth extraction. Following random allocation, 20 peri-implant bone dehiscences were grafted with a soft-type block made of synthetic biphasic calcium phosphate (BCP) + collagen and 20 bone deh
Research Areas
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