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Woo Jin Hyung

Yonsei University · Medicine

About the Lab

Professor Woo Jin Hyung's research lab specializes in minimally invasive and robotic surgery for gastric cancer, with a strong focus on oncological outcomes, long-term survival, and biomarker-driven treatment strategies. The lab investigates the non-inferiority of laparoscopic and robotic gastrectomy compared to open surgery, particularly in locally advanced and early-stage gastric cancers. Key research directions include microsatellite instability (MSI) and PD-L1 expression as predictive biomarkers for chemotherapy response and prognosis in stage II/III gastric cancer.

gastric cancerminimally invasive surgeryoncological outcomesbiomarkerslaparoscopic gastrectomy

Research Overview

Papers
450
Total Citations
21,248
Papers (5y)
77
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
77total
2021
2022
2023
2024
2025
Citations per year (5y)
1,806total
20212022202320242025

Selected Papers

15
1
Article|506 citations·2019
Effect of Laparoscopic Distal Gastrectomy vs Open Distal Gastrectomy on Long-term Survival Among Patients With Stage I Gastric Cancer
Hyung-Ho Kim, Sang‐Uk Han, Min-Chan Kim, Wook Kim, Hyuk‐Joon Lee, Seung Wan Ryu, Gyu Seok Cho, Chan Young Kim, Han‐Kwang Yang, Do Joong Park, Taeil Son, Sang Il Lee
SJR Q1JAMA OncologyOA

IMPORTANCE: Laparoscopic distal gastrectomy is gaining popularity over open distal gastrectomy for gastric cancer because of better early postoperative outcomes. However, to our knowledge, no studies have proved whether laparoscopic distal gastrectomy is oncologically equivalent to open distal gastrectomy. OBJECTIVE: To examine whether the long-term survival among patients with stage I gastric cancer undergoing laparoscopic distal gastrectomy is noninferior to that among patients undergoing open

Pulmonary and Respiratory MedicineMedicine
2
Article|398 citations·2020
Long-Term Outcomes of Laparoscopic Distal Gastrectomy for Locally Advanced Gastric Cancer: The KLASS-02-RCT Randomized Clinical Trial
Woo Jin Hyung, Han‐Kwang Yang, Young-Kyu Park, Hyuk-Joon Lee, Ji Yeong An, Wook Kim, Hyoung‐Il Kim, Hyung‐Ho Kim, Seung Wan Ryu, Hoon Hur, Min‐Chan Kim, Seong‐Ho Kong
SJR Q1Journal of Clinical OncologyOA

PURPOSE It is unclear whether laparoscopic distal gastrectomy for locally advanced gastric cancer is oncologically equivalent to open distal gastrectomy. The noninferiority of laparoscopic subtotal gastrectomy with D2 lymphadenectomy for locally advanced gastric cancer compared with open surgery in terms of 3-year relapse-free survival rate was evaluated. PATIENTS AND METHODS A phase III, open-label, randomized controlled trial was conducted for patients with histologically proven locally advanc

Pulmonary and Respiratory MedicineMedicine
3
Article|314 citations·2015
Multicenter Prospective Comparative Study of Robotic Versus Laparoscopic Gastrectomy for Gastric Adenocarcinoma
Hyoung‐Il Kim, Sang‐Uk Han, Han‐Kwang Yang, Young‐Woo Kim, Hyuk‐Joon Lee, Keun Won Ryu, Joong‐Min Park, Ji Yeong An, Min-Chan Kim, Sung Soo Park, Kyo Young Song, Sung Jin Oh
SJR Q1Annals of Surgery

The use of robotic systems is assumed to provide a technically superior operative environment for minimally invasive surgery. However, our analysis of perioperative surgical outcomes indicated that robotic gastrectomy is not superior to laparoscopic gastrectomy. Clinical trials identification: NCT01309256.

Pulmonary and Respiratory MedicineMedicine
4
Article|287 citations·2009
Robot-Assisted Gastrectomy With Lymph Node Dissection for Gastric Cancer
Jyewon Song, Sung Jin Oh, Wook Ho Kang, Woo Jin Hyung, Seung Ho Choi, Sung Hoon Noh
SJR Q1Annals of SurgeryOA

This study demonstrated that RAG with lymphadenectomy can be applied safely and effectively for patients with gastric cancer.

Pulmonary and Respiratory MedicineMedicine
5
Article|244 citations·2018
Microsatellite Instability and Programmed Cell Death-Ligand 1 Expression in Stage II/III Gastric Cancer
Yoon Young Choi, Hyunki Kim, Su‐Jin Shin, Ha Yan Kim, Jinae Lee, Han‐Kwang Yang, Woo Ho Kim, Young‐Woo Kim, Myeong‐Cherl Kook, Young Kyu Park, Hyung‐Ho Kim, Hye Seung Lee
SJR Q1Annals of SurgeryOA

OBJECTIVE: We investigated microsatellite instability (MSI) status and programed cell death ligand 1 (PD-L1) expression as predictors of prognosis and responsiveness to chemotherapy for stage II/III gastric cancer. BACKGROUND: The clinical implications of MSI status and PD-L1 expression in gastric cancer have not been well-elucidated. METHODS: Tumor specimens and clinical information were collected from patients enrolled in the CLASSIC trial-a randomized controlled study of capecitabine plus oxa

Pulmonary and Respiratory MedicineMedicine
6
Article|205 citations·2008
Risk Factors Associated with Complication Following Laparoscopy-Assisted Gastrectomy for Gastric Cancer: A Large-Scale Korean Multicenter Study
Min Chan Kim, Wook Kim, Hyung‐Ho Kim, Seung Wan Ryu, Seong Yeob Ryu, Kyo Young Song, Hyukjoon Lee, Gyu Seok Cho, Sang‐Uk Han, Woo Jin Hyung, Korean Laparoscopic Gastrointestinal Surgery Study (KLASS) Group
SJR Q1Annals of Surgical OncologyOA
Pulmonary and Respiratory MedicineMedicine
7
Article|176 citations·2001
Early gastric carcinoma with signet ring cell histology
Woo Jin Hyung, Sung Hoon Noh, Jun Ho Lee, Jihun J. Huh, Ki Hyeok Lah, Seung Ho Choi, Jin Sik Min
SJR Q1CancerOA

BACKGROUND: There has been much controversy surrounding the biologic behavior and prognosis of early stage gastric signet ring cell carcinoma (SRC). To clarify the biologic behavior of early stage gastric SRC (early SRC), we compared the clinicopathologic features and prognosis of early SRC with other histologic types. METHODS: A total of 933 patients with early gastric carcinoma who had undergone gastrectomy from 1987 to 1995 were retrospectively analyzed. Among them, 263 patients with SRC were

Pulmonary and Respiratory MedicineMedicine
8
Article|174 citations·2018
A feasibility study of laparoscopic total gastrectomy for clinical stage I gastric cancer: a prospective multi-center phase II clinical trial, KLASS 03
Woo Jin Hyung, Han‐Kwang Yang, Sang‐Uk Han, Young‐Jun Lee, Joong‐Min Park, Jin-Jo Kim, Oh Kyung Kwon, Seong Ho Kong, Hyoung‐Il Kim, Hyuk‐Joon Lee, Wook Kim, Seung Wan Ryu
SJR Q1Gastric CancerOA
Pulmonary and Respiratory MedicineMedicine
9
Article|172 citations·2018
Fluorescent Lymphography–Guided Lymphadenectomy During Robotic Radical Gastrectomy for Gastric Cancer
In Gyu Kwon, Taeil Son, Hyoung‐Il Kim, Woo Jin Hyung
SJR Q1JAMA SurgeryOA

This study's findings suggest that fluorescent lymphography may be useful intraoperatively for identifying and retrieving all necessary lymph nodes for a complete and thorough lymphadenectomy.

Pulmonary and Respiratory MedicineMedicine
10
Article|167 citations·2009
Role of robotic gastrectomy using da Vinci system compared with laparoscopic gastrectomy: initial experience of 20 consecutive cases
Jyewon Song, Wook Ho Kang, Sung Jin Oh, Woo Jin Hyung, Seung Ho Choi, Sung Hoon Noh
SJR Q1Surgical EndoscopyOA
Pulmonary and Respiratory MedicineMedicine
11
Article|164 citations·2014
Robotic spleen-preserving total gastrectomy for gastric cancer: comparison with conventional laparoscopic procedure
Taeil Son, Joong Ho Lee, Yoo Min Kim, Hyoung‐Il Kim, Sung Hoon Noh, Woo Jin Hyung
SJR Q1Surgical EndoscopyOA
Pulmonary and Respiratory MedicineMedicine
12
Article|142 citations·2017
Long-term oncologic outcomes of robotic gastrectomy for gastric cancer compared with laparoscopic gastrectomy
Kazutaka Obama, Yoo-Min Kim, Dae Ryong Kang, Taeil Son, Hyoung‐Il Kim, Sung Hoon Noh, Woo Jin Hyung
SJR Q1Gastric CancerOA
Pulmonary and Respiratory MedicineMedicine
13
Article|134 citations·2011
Rapid adaptation of robotic gastrectomy for gastric cancer by experienced laparoscopic surgeons
Sung Soo Park, Min-Chan Kim, Man Sik Park, Woo Jin Hyung
SJR Q1Surgical Endoscopy
Pulmonary and Respiratory MedicineMedicine
14
Article|131 citations·2010
Recurrence Following Laparoscopy-Assisted Gastrectomy for Gastric Cancer: A Multicenter Retrospective Analysis of 1,417 Patients
Korean Laparoscopic Gastrointestinal Surgery Study (KLASS) Group, Jyewon Song, Hyuk‐Joon Lee, Gyu Seok Cho, Sang‐Uk Han, Min‐Chan Kim, Seung Wan Ryu, Wook Kim, Kyo Young Song, Hyung‐Ho Kim, Woo Jin Hyung
SJR Q1Annals of Surgical OncologyOA
Pulmonary and Respiratory MedicineMedicine
15
Article|121 citations·2015
Robotic distal subtotal gastrectomy with D2 lymphadenectomy for gastric cancer patients with high body mass index: comparison with conventional laparoscopic distal subtotal gastrectomy with D2 lymphadenectomy
Juhan Lee, Yoo-Min Kim, Yanghee Woo, Kazutaka Obama, Sung Hoon Noh, Woo Jin Hyung
SJR Q1Surgical EndoscopyOA
Pulmonary and Respiratory MedicineMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryGastroenterologyOncologyPathology and Forensic MedicineCancer Research

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