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Wooseok Sim

Sungkyunkwan University · Medicine

About the Lab

Professor Wooseok Sim's research lab specializes in clinical anesthesiology and pain medicine, with a primary focus on optimizing postoperative analgesia and minimizing complications in thoracic and abdominal surgeries. The lab investigates the efficacy and safety of various analgesic techniques—such as thoracic epidural and intravenous patient-controlled analgesia—in enhancing patient recovery and reducing postoperative complications, including arrhythmias and chronic pain. A significant emphasis is placed on improving diagnostic accuracy and procedural safety in image-guided interventions, such as lumbar medial branch blocks, through real-time fluoroscopy. The lab also contributes to the development of evidence-based clinical guidelines for managing herpes zoster and postherpetic neuralgia.

postoperative analgesiathoracic epiduralpain managementfluoroscopy-guided proceduresherpes zoster neuralgia

Research Overview

Papers
67
Total Citations
410
Papers (5y)
9
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
9total
2014
2015
2016
2022
2023
Citations per year (5y)
34total
20142015201620222023

Selected Papers

15
1
Article|55 citations·2009
Is Intravenous Patient Controlled Analgesia Enough for Pain Control in Patients Who Underwent Thoracoscopy?
Jie Ae Kim, Tae Hyong Kim, Mikyung Yang, Mi Sook Gwak, Gaab Soo Kim, Myung‐Joo Kim, Hyun Sung Cho, Woo Seok Sim
SJR Q2Journal of Korean Medical ScienceOA

This prospective randomized study was conducted to evaluate the efficacy of two common analgesic techniques, thoracic epidural patient-controlled analgesia (Epidural PCA), and intravenous patient-controlled analgesia (IV PCA), in patients undergoing lobectomy by the video-assisted thoracic surgical (VATS) approach. Fifty-two patients scheduled for VATS lobectomy were randomly allocated into two groups: an Epidural PCA group receiving an epidural infusion of ropivacaine 0.2%+fentanyl 5 microg/mL

SurgeryMedicine
2
Article|47 citations·2008
Intravascular Injection in Lumbar Medial Branch Block: A Prospective Evaluation of 1433 Injections
Chul Joong Lee, Yong Chul Kim, Jae Hyuck Shin, Francis Sahngun Nahm, Hyo Min Lee, Yun Suk Choi, Sang Chul Lee, Justin Sang Ko, Tae Hyeong Kim, Woo Seok Sim, Chung Su Kim, Hyun Sung Cho
SJR Q1Anesthesia & Analgesia

The aspiration test with or without spot radiography frequently missed the intravascular uptake of contrast during lumbar MBBs. We strongly advocate the use of real-time fluoroscopy during contrast injection to increase diagnostic and therapeutic value and to avoid possible complications.

Pathology and Forensic MedicineMedicine
3
Article|33 citations·2009
Is Intravenous Patient Controlled Analgesia Enough for Pain Control in Patients Who Underwent Thoracoscopy?
김지애, 김태형, 양미경, 곽미숙, 김갑수, 김명주, 조현성, 심우석
Journal of Korean Medical Science

This prospective randomized study was conducted to evaluate the efficacy of two common analgesic techniques, thoracic epidural patient-controlled analgesia (Epidural PCA), and intravenous patient-controlled analgesia (IV PCA), in patients undergoing lobectomy by the video-assisted thoracic surgical (VATS) approach. Fifty-two patients scheduled for VATS lobectomy were randomly allocated into two groups: an Epidural PCA group receiving an epidural infusion of ropivacaine 0.2%+fentanyl 5 ㎍/mL combi

4
Article|28 citations·2005
Thoracic epidural anesthesia does not improve the incidence of arrhythmias after transthoracic esophagectomy
Hyun Joo Ahn, Woo Seok Sim, Young Mog Shim, Jie Ae Kim
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

OBJECTIVE: The incidence of arrhythmias related to an esophagectomy is high, and its clinical significance has been well accepted. Thoracic epidural anesthesia (TEA) can modulate the sympathetic tone and neuroendocrine responses associated with major operation. This study was aimed to evaluate the effects of TEA on the incidence of arrhythmias in transthoracic esophagectomy patients. METHODS: The records of 185 patients who underwent the Ivor-Lewis operation between 2001 and 2004 by the same ope

SurgeryMedicine
5
Article|26 citations·2008
Treatment of Herpes Zoster and Postherpetic Neuralgia
Woo Seok Sim, Jin Hwan Choi, Kyung Ream Han, Yong Chul Kim
The Korean Journal of Pain

접수일:2008년 7월 26일, 승인일:2008년 7월 31일 책임저자:김용철, (110-460) 서울시 종로구 연건동 28 서울대학교병원 마취통증의학과 Tel: 02-2072-3289, Fax: 02-747-5639 E-mail: pain@snu.ac.kr 이 논문은 대한마취과학회 주관 하에 마련된 대상포진 및 대상포진후신 경통의 표준진료지침의 초안을 요약 정리한 것임. Received July 26, 2008, Accepted July 31, 2008 Correspondence to: Yong Chul Kim Department of Anesthesiology and Pain Medicine, Seoul National University College of Medicine, 28, Yeongeon-dong, Jongno-gu, Seoul 110-460, Korea Tel: +82-2-2072-3289, Fax: +82-2-747-5639 E-mail: pain@snu.ac.kr

EpidemiologyMedicine
6
Article|25 citations·2008
대상포진 및 대상포진후신경통 환자의 치료
심우석, 최진환, 한경림, 김용철

Numerous treatment modalities for acute or subacute herpes zoster and postherpetic neuralgia have been introduced. Therefore, we updated the treatment modalities by conducting a wide review of the medical literature and we created a new treatment algorithm for herpes zoster and postherpetic neuralgia. (Korean J Pain 2008; 21: 93-105)

7
Article|22 citations·2016
Effect of Cervical Interlaminar Epidural Steroid Injection: Analysis According to the Neck Pain Patterns and MRI Findings
Ji Won Choi, Hyung Woo Lim, Jin Young Lee, Won Il Lee, Eun Kyung Lee, Choo Hoon Chang, Jae Young Yang, 심우석

Background: It is widely accepted that cervical interlaminar steroid injection (CIESI) is more effective in treating radicular pain than axial neck pain, but without direct comparison. And the differences of effect after CIESI according to MRI findings are inconsistent. In this retrospective study, we evaluated the therapeutic response of CIESI according to pain sites, durations, MRI findings, and other predictive factors altogether, unlike previous studies, which evaluated them separately. Meth

8
Article|7 citations·2011
A Comparison of the Effects of Preanesthetic Administration of Crystalloid Versus Colloid on Intrathecal Spread of Isobaric Spinal Anesthetics and Cerebrospinal Fluid Movement
Byung Seop Shin, Chung Su Kim, Woo Seok Sim, Chul Joong Lee, Sung Tae Kim, Gunn Hee Kim, Si Ra Bang, Sang Hyun Lee, Sun Ji Hyun, Gaab Soo Kim
SJR Q1Anesthesia & Analgesia

Compared with a colloid preload, which may be comparable to the no-preload condition, crystalloid preload prolonged the time to reach the peak sensory block level in isobaric spinal anesthesia, which might have been caused by a significant decrease in CSF pulsatile movement. This attenuated CSF pulsatile movement in the crystalloid preload group might have resulted from significant increases of CSF production.

SurgeryMedicine
9
Article|7 citations·2004
Radiofrequency Lumbar Medial Branch Denervation Using Bipolar Probe in Patient with Facet Joint Syndrome
Woo Seok Sim, Ae Ryoung Lee
The Korean Journal of Pain

Background: The facet joint is one structure that can cause lower back pain and radiofrequency (RF) denervation of the medial branch has been shown to be effective in treating this type of pain. However, the proper positioning of needle to the medial branch by sensory testing may be difficult when there are severe degenerative changes in the spine. In these cases, bipolar electrodes might be effective in making a wider strip lesion as in a sacroiliac joint. This study performed an RF facet dener

Pathology and Forensic MedicineMedicine
11
Article|4 citations·2005
Zoster Sine Herpete는 원인을 모르는 늑간신경통의 원인인가?- 증례 보고 -
심우석, 김용철, 여진석

Zoster sine herpete (ZSH) is a varicella zoster virus (VZV) reactivation without a zoster that is difficult to diagnose early after onset. This study examined 12 patients who presented with intercostal neuralgia, had no history of trauma, cutaneous eruption and no scar of a herpes zoster on the lesion. Two patients had a vertebral compression fracture. Two patients had a history of a zoster in the other site. No other suspicious findings were observed. Ten of the twelve patients were checked for

12
Article|3 citations·2005
Delayed Subarachnoid Migration of an Epidural Catheter: A case report
Woo Seok Sim, Ae Ryoung Lee, Tae‐Hyoung Kim
SJR Q1Korean Journal of AnesthesiologyOA

(patient controlled analgesia, PCA) PCA . . 1) PCA (subarachnoid space) , ,

NeurologyMedicine
13
Article|3 citations·2011
Application of Botulinum Toxin in Pain Management
심우석

Botulinum toxin has been used for the treatment of many clinical disorders by producing temporary skeletal muscle relaxation. In pain management, botulinum toxin has demonstrated an analgesic effect by reducing muscular hyperactivity, but recent studies suggest this neurotoxin could have direct analgesic mechanisms different from its neuromuscular actions. At the moment, botulinum toxin is widely investigated and used in many painful diseases such as myofascial syndrome, headaches, arthritis, an

14
Article|2 citations·2005
난치성 흉통 환자에서 발견된 양성 및 악성 종양 - 증례 보고 -
심우석, 권민아, 박정헌, 유래근, 김태형

Many patients with intractable chest pain visit pain clinics, two of which, with rare cases of an intraspinal tumor and malignant mesothelioma were experiences at our clinic. A 37-year old female patient presented with exacerbating chest pain, but without neurological manifestations, of 15-months duration. Her laboratory findings, such as blood tests, chest X-ray, EKG, abdominal ultrasonography and chest CT, were normal. MRI revealed an intradural extramedullary schwannoma at the T 5 and 6 level

15
Article|2 citations·2006
추간판 탈출증 환자에서 길잡이철사가 삽입된 경막외카테터를 이용한 미추경막외조영술
심우석, 김지애, 함태수, 김갑수, 조현성, 김태형, 고상욱, 이석진, 황희윤, 최수주, 김정수

=Caudal Epidural Injection with a Guidewire-Reinforced Epidural Catheter inPatients with Herniated Nucleosus PulposeJustin Sangwook Ko, M.D., Seok Jin Lee, M.D., Hee Youn Hwang, M.D., Woo Seok Sim, M.D.,Soo Joo Choi, M.D., Jie Ae Kim, M.D., Chung Su Kim, M.D., Tae Soo Hahm, M.D.,Gaab Soo Kim, M.D., Hyun Sung Cho, M.D., and Tae Hyeong Kim, M.D.

Research Areas

SurgeryPathology and Forensic MedicineNeurologyEpidemiologyPulmonary and Respiratory MedicineEmergency Medicine

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