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Yeon Seok Choi

Kyung Hee University · Medicine

About the Lab

Professor Yeon Seok Choi's research lab specializes in respiratory medicine and thoracic oncology, with a strong focus on chronic obstructive pulmonary disease (COPD), lung cancer, and interstitial lung diseases. The lab investigates clinical phenotypes, imaging biomarkers, and genomic alterations in lung adenocarcinoma and nontuberculous mycobacterial (NTM) infections, aiming to improve diagnosis, prognosis prediction, and personalized treatment strategies. Key research directions include the application of advanced imaging techniques such as parametric response mapping (PRM) and multidetector CT for assessing small airway disease and tumor characteristics, as well as longitudinal analysis of disease progression in COPD patients exposed to environmental dust. The lab integrates clinical, radiological, and molecular data to enhance understanding of disease mechanisms and patient outcomes.

COPDlung adenocarcinomamedical imaginggenomic alterationsnontuberculous mycobacteria

Research Overview

Papers
22
Total Citations
108
Papers (5y)
13
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2020
2021
2023
2024
2025
Citations per year (5y)
83total
20202021202320242025

Selected Papers

15
1
Article|32 citations·2021
Clinical Characteristics of COPD Patients According to COPD Assessment Test (CAT) Score Level: Cross-Sectional Study
Hyun‐Il Gil, Sungmin Zo, Paul Jones, Bo‐Guen Kim, Noeul Kang, Yeonseok Choi, Hyun Kyu Cho, Danbee Kang, Juhee Cho, Hye Yun Park, Sun Hye Shin
SJR Q1International Journal of COPDOA

PURPOSE: The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is widely used to assess the impact of COPD symptoms on health status. Whilst the CAT consists of eight different items, details on the distribution of each item are limited. This study aimed to investigate the distribution and clinical implication of each CAT item, stratified by CAT severity group, in stable COPD patients. PATIENTS AND METHODS: This was a cross-sectional study at a single referral hospital in South

Pulmonary and Respiratory MedicineMedicine
2
Article|16 citations·2020
Clinicoradiopathological features and prognosis according to genomic alterations in patients with resected lung adenocarcinoma
Yeonseok Choi, Kihwan Kim, Byeong‐Ho Jeong, Kyung Jong Lee, Hojoong Kim, O Jung Kwon, Young Tae Kim, Yoon‐La Choi, Ho Yun Lee, Sang‐Won Um
SJR Q2Journal of Thoracic DiseaseOA

Genomic alterations are associated with clinicoradiopathologic features in patients with resected lung adenocarcinoma. Identifying genomic alterations could help to predict the prognosis of early-stage lung adenocarcinoma.

Pulmonary and Respiratory MedicineMedicine
3
Article|15 citations·2023
The Incidence and Risk Factors of Chronic Pulmonary Infection after Radiotherapy in Patients with Lung Cancer
Yeonseok Choi, Jae Myoung Noh, Sun Hye Shin, Kyungjong Lee, Sang‐Won Um, Hojoong Kim, Hongryull Pyo, Yong Chan Ahn, Byeong‐Ho Jeong
SJR Q1Cancer Research and TreatmentOA

PURPOSE: This study aimed to investigate cumulative incidence and risk factors associated with chronic pulmonary infection (CPI) development after radiotherapy for lung cancer. Materials and Methods: We retrospectively analyzed 1,872 patients with lung cancer who received radiotherapy for lung cancer from 2010-2014, had a follow-up period of ≥ 3 months after radiotherapy, and did not have CPI at the time of radiotherapy. CPI was defined as pulmonary tuberculosis, non-tuberculous mycobacterial pu

Pulmonary and Respiratory MedicineMedicine
4
Article|12 citations·2019
Clinical Characteristics and Outcomes of Surgically Resected Solitary Pulmonary Nodules Due to Nontuberculous Mycobacterial Infections
Yeonseok Choi, Byung Woo Jhun, Jhingook Kim, Hee Jae Huh, Nam Yong Lee
SJR Q1Journal of Clinical MedicineOA

Background: Limited data are available regarding the detailed characteristics and outcomes of surgically resected nontuberculous mycobacterial (NTM) granulomas. Methods: We evaluated the characteristics of 49 NTM granulomas presenting as solitary pulmonary nodules (SPNs) between January 2007 and December 2016. Results: Twenty-five patients (51%) were male and 27 (55%) were never-smokers. Seven (14%) patients had a history of tuberculosis. More than half (51%) of patients were asymptomatic. On ch

EpidemiologyMedicine
5
Article|6 citations·2020
Clinical T category for lung cancer staging: A pragmatic approach for real‐world practice
Yeonu Choi, Sun‐Hyung Kim, Ki Hwan Kim, Yeonseok Choi, Sung Goo Park, Insuk Sohn, Hye Seung Kim, Sang‐Won Um, Ho Yun Lee
SJR Q2Thoracic CancerOA

BACKGROUND: To determine which components should be measured and which window settings are appropriate for computerized tomography (CT) size measurements of lung adenocarcinoma (ADC) and to explore interobserver agreement and accuracy according to the eighth edition of TNM staging. METHODS: A total of 165 patients with surgically resected lung ADC earlier than stage 3A were included in this study. One radiologist and two pulmonologists independently measured the total and solid sizes of componen

Pulmonary and Respiratory MedicineMedicine
6
Article|5 citations·2025
Longitudinal parametric response mapping on CT in assessing functional small airway disease and emphysema in COPD
Taeyun Kim, Youlim Kim, So Hyeon Bak, Sun Hye Shin, Ho Yun Lee, Yunjoo Im, Yeonseok Choi, Woo Jin Kim, Hye Yun Park
SJR Q1Scientific ReportsOA

Parametric response mapping (PRM) on computed tomography (CT) is an imaging technique for assessing small airway disease (SAD) and emphysema in chronic obstructive pulmonary disease (COPD). This study was aimed to examine the relationship between individual spirometry components decline and PRM-CT-derived data changes over a 6-year observation period in mild and moderate COPD patients using a COPD cohort chronically exposed to dust. This study utilized longitudinal data of the COPD in Dusty Area

Pulmonary and Respiratory MedicineMedicine
7
Article|4 citations·2019
Clinical characteristics and outcomes of surgically resected solitary pulmonary nodules due to nontuberculous mycobacterial infections
Yeonseok Choi, Byung Woo Jhun, Sang‐Won Um, Hojoong Kim, Oh‐Jung Kwon, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Young Mog Shim, Hee Jae Huh, Nam Yong Lee, Won‐Jung Koh

Granulomas caused by nontuberculous mycobacterial (NTM) pulmonary infections can present as solitary pulmonary nodules (SPNs) mimicking pulmonary malignancies or other infectious granulomas. However, limited data are available regarding the detailed characteristics and outcomes of surgically resected NTM granulomas. We evaluated the characteristics of 49 surgically resected NTM granulomas presenting as SPNs of 49 patients between January 2007 and December 2016. Twenty-five (51%) were male and 27

EpidemiologyMedicine
8
Article|4 citations·2018
Unilateral pulmonary artery agenesis manifested by hemoptysis in pregnancy
Yeonseok Choi, Noeul Kang, Yunjoo Im, Junsu Choe, Tae Jung Kim, Hojoong Kim
SJR Q3Respiratory Medicine Case ReportsOA

Unilateral pulmonary artery agenesis (UPAA) is a rare congenital anomaly which can be symptomatic or even asymptomatic. Most of patients with isolated UPAA have mild symptoms and it is difficult to be diagnosed, especially when abnormal findings of chest radiograph are the first presentation. It is often misdiagnosed and is not considered during differential diagnosis. To make a diagnosis of UPAA, various imaging modalities including chest radiograph, computed tomography (CT), and angiography ar

Pulmonary and Respiratory MedicineMedicine
9
Article|4 citations·2021
Favorable Response to Long-Term Azithromycin Therapy in Bronchiectasis Patients with Chronic Airflow Obstruction Compared to Chronic Obstructive Pulmonary Disease Patients without Bronchiectasis
Yeonseok Choi, Sun Hye Shin, Hyun Lee, Hyun Kyu Cho, Yunjoo Im, Noeul Kang, Hye Sook Choi, Hye Yun Park
SJR Q1International Journal of COPDOA

Bronchiectasis patients with CAO could benefit more from long-term azithromycin treatment than COPD patients without bronchiectasis.

Pulmonary and Respiratory MedicineMedicine
10
Article|4 citations·2018
A rare case of numerous thoracolithiasis with chest discomfort
Noeul Kang, Yeonseok Choi, Yunjoo Im, Junsu Choe, Jhingook Kim, Joungho Han, T. J. Kim, Hojoong Kim
SJR Q3Respiratory Medicine Case ReportsOA

Thoracolithiasis is a rare benign condition with mobile free bodies in the pleural cavity. It is asymptomatic and mostly found incidentally. Up to our knowledge there is no report of symptomatic numerous thoracolithiasis. We report a very rare case of thoracolithiasis in a 36-year-old female with chest discomfort. Images from computed tomography presented a chain of small non-enhancing nodules in the left hemi-diaphragmatic pleura. Exploratory thoracoscopy was performed and twenty-five mobile pe

RheumatologyMedicine
11
Article|3 citations·2024
Causal inference analysis of the radiologic progression in the chronic obstructive pulmonary disease
Yunjoo Im, Kwonsang Lee, Sang Min Lee, Sun Hye Shin, Yeonseok Choi, Jae‐Seung Lee, Yeon‐Mok Oh, Jong‐Hoon Kim, You Jin Oh, Ho Yun Lee, Hye Yun Park
SJR Q1Scientific ReportsOA

There is limited evidence regarding the causal inference of emphysema and functional small airway disease in the subsequent progression of chronic obstructive pulmonary disease (COPD). Patients consisting of two independent cohorts diagnosed with COPD and underwent two serial chest CT scans were included. Total percent emphysema (PRM Emph ) and fSAD (PRM fSAD ) was quantified via PRM. To investigate the progression of emphysema, we divided COPD patients with PRM Emph < 10% into low and high PRM

Pulmonary and Respiratory MedicineMedicine
12
Article|2 citations·2024
Association of moderate-to-vigorous physical activity with reduction of acute exacerbation in COPD patients using a dual ultra-long-acting bronchodilators
Taeyun Kim, Hyunsoo Kim, Sun Hye Shin, Yunjoo Im, Sunga Kong, Hye Sook Choi, Sungmin Zo, Sang Hyuk Kim, Yeonseok Choi, Danbee Kang, Hye Yun Park
SJR Q1Scientific ReportsOA

Inhaler therapy and physical activity (PA) are important methods of chronic obstructive pulmonary disease (COPD) management. This study aimed to investigate the additional benefit of moderate-to-vigorous PA (MVPA) in patients with COPD using a long-acting beta-agonists (LABA)/long-acting muscarinic antagonist (LAMA) combination. We emulated a target trial to estimate the benefit of MVPA in patients with COPD using a dual ultra-long-acting bronchodilators. We enrolled patients aged ≥ 40 who were

Pulmonary and Respiratory MedicineMedicine
13
Article|1 citations·2018
THE USE OF SURGERY IN A REAL-WORLD CLINIC TO DIAGNOSE AND TREAT PULMONARY CRYPTOCOCCOSIS IN IMMUNOCOMPETENT PATIENTS
Bumhee Yang, Yeonseok Choi, Ji Yeon Kang, Sun‐Hyung Kim, Hojoong Kim, Kyung Soo Lee, Sumin Shin, Hyun Lee
SJR Q1CHEST Journal
EpidemiologyMedicine
14
Article|0 citations·2019
COPD AND ASTHMA‐COPD OVERLAP: DIFFERENCES IN CLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES
Yeonseok Choi, Hyun Cho, Sun Hye Shin, Hye Sang Park
SJR Q1RespirologyOA

than NHW and AA (56.3% and 54.6%, P <0.01). The average body mass index (BMI) of NHW and AA was similar (27.9 kg/m2 for both), but Koreans had significantly lower BMI (22.4 kg/m2, P <0.01). SGRQ total score was highest among AA (40.1.), followed by NHW (35.9), and Koreans (35.3, P <0.01). Compared to NHW, AA and Koreans had significantly increased adjusted prevalence ratios (aPRs) of diabetes mellitus (1.63 and 1.58) and decreased aPRs of dyslipidaemia (0.80 and 0.23), gastro-oesophageal reflux

Pulmonary and Respiratory MedicineMedicine
15
Article|0 citations·2024
18F-Fluorodeoxyglucose positron emission tomography/computed tomography for assessing treatment response of nontuberculous mycobacterial pulmonary disease
Yeonseok Choi, Joon Young Choi, Byung Woo Jhun

<bold>Background:</bold> This study aimed to investigate the role of <sup>18</sup>F-Fluorodeoxyglucose (<sup>18</sup>F-FDG) positron emission tomography/computed tomography (PET/CT) in treatment response assessment of nontuberculous mycobacterial pulmonary disease (NTM-PD). <bold>Methods:</bold> We evaluated 26 patients with NTM-PD who underwent NTM-PD treatment and serial <sup>18</sup>F-FDG PET/CT at baseline and 6 and 12 months after treatment. On PET images, the highest lung maximum standardi

EpidemiologyMedicine

Research Areas

Pulmonary and Respiratory MedicineEpidemiologyRheumatologyGeneticsPublic Health, Environmental and Occupational HealthCritical Care and Intensive Care Medicine

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