Yong‐Jae Lee
Yonsei University · Medicine
About the Lab
Professor Yong-Jae Lee's research lab specializes in interdisciplinary biomedical and materials science research, focusing on the development of advanced optical devices for enhanced light extraction in organic semiconductors and the investigation of environmental and biological factors influencing chronic disease progression. The lab integrates computational modeling with experimental validation to optimize photonic structures in optoelectronic devices and explores the clinical and epidemiological links between environmental pollutants, metabolic markers, and systemic diseases such as cancer, cardiovascular disease, and non-alcoholic fatty liver disease. Additionally, the lab examines the role of traditional herbal compounds and routine blood biomarkers in predicting and managing metabolic and inflammatory disorders.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15To improve light extraction from organic light-emitting diodes (OLEDs), we introduced a photonic crystal pattern into the glass substrate of an OLED. The periodic modulation converts the guided waves in the high-refractive-index indium-tin-oxide/organic layers into external leaky waves. We used the finite-difference time-domain method to optimize the structural parameters of the photonic crystal pattern and to analyze the microcavity effect by the metallic cathode of the OLED. With the use of an
The aim of this study was to examine the relationship between main air pollutants and all cancer mortality by performing a meta-analysis. We searched PubMed, EMBASE (a biomedical and pharmacological bibliographic database of published literature produced by Elsevier), and the reference lists of other reviews until April 2018. A random-effects model was employed to analyze the meta-estimates of each pollutant. A total of 30 cohort studies were included in the final analysis. Overall risk estimate
Since ancient times, licorice, the root of <i>Glycyrrhiza glabra</i>, has been known to have a wide spectrum of therapeutic effects. Glycyrrhizin is cleaved to glycyrrhizic acid, which is subsequently converted to glycyrrhetic acid by human intestinal microflora. Glycyrrhetic acid is a potent inhibitor of 11<i>β</i>-hydroxysteroid dehydrogenase (11<i>β</i>-HSD) and performs a range of corticosteroid-like activities. The pharmacologic effects of licorice contribute to its anti-inflammatory, antio
Complete blood count (CBC) is one of the most common blood tests requested by clinicians and evaluates the total numbers and characteristics of cell components in the blood. Recently, many investigations have suggested that the risk of cancer, cardiovascular disease (CVD), arteriosclerosis, type 2 diabetes (T2DM), and metabolic syndrome can be predicted using CBC components. This review introduces that white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR), hemoglobin (Hb), mean corpuscula
AIM: To investigate the relationship between knee osteoarthritis, mental health and health-related quality of life (QoL). METHODS: This study included 6343 men and women aged ≥50 years from the Korean National Health and Nutrition Examination Survey. Osteoarthritis was defined as Kellgren-Lawrence grade ≥2 in the knee on radiographic images with knee pain. Mental health and health-related QoL were assessed according to three dimensions (depressive mood, psychological distress and suicidal ideati
BACKGROUND: Increased uric acid is associated with the metabolic syndrome, conditions linked to oxidative stress and insulin resistance. Non-alcoholic fatty liver disease (NAFLD) is now considered a hepatic manifestation of insulin resistance. However, little has been written regarding the association between uric acid and NAFLD. METHODS: We examined the association between uric acid and the presence of NAFLD in 3768 Koreans (2133 men, 1635 women; aged 20-75 years) in a health examination progra
Vitamin D is an essential component of bone and mineral metabolism; its deficiency causes growth retardation and skeletal deformities in children and osteomalacia and osteoporosis in adults. Hypovitaminosis D (vitamin D insufficiency or deficiency) is observed not only in adults but also in infants, children, and adolescents. Previous studies suggest that sufficient serum vitamin D levels should be maintained in order to enhance normal calcification of the growth plate and bone mineralization. M
OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the
Research Areas
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