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Yong‐Jae Lee

Yonsei University · Medicine

About the Lab

Professor Yong-Jae Lee's research lab specializes in interdisciplinary biomedical and materials science research, focusing on the development of advanced optical devices for enhanced light extraction in organic semiconductors and the investigation of environmental and biological factors influencing chronic disease progression. The lab integrates computational modeling with experimental validation to optimize photonic structures in optoelectronic devices and explores the clinical and epidemiological links between environmental pollutants, metabolic markers, and systemic diseases such as cancer, cardiovascular disease, and non-alcoholic fatty liver disease. Additionally, the lab examines the role of traditional herbal compounds and routine blood biomarkers in predicting and managing metabolic and inflammatory disorders.

optoelectronic devicesmetabolic syndromeenvironmental pollutantsbiomarkerschronic disease

Research Overview

Papers
433
Total Citations
10,762
Papers (5y)
89
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
89total
2022
2023
2024
2025
2026
Citations per year (5y)
1,197total
20222023202420252026

Selected Papers

15
1
Article|337 citations·2003
A high-extraction-efficiency nanopatterned organic light-emitting diode
Yong‐Jae Lee, Se‐Heon Kim, Joon Huh, Guk-Hyun Kim, Yong-Hee Lee, Sang‐Hwan Cho, Yoon‐Chang Kim, Young Rag
SJR Q1Applied Physics Letters

To improve light extraction from organic light-emitting diodes (OLEDs), we introduced a photonic crystal pattern into the glass substrate of an OLED. The periodic modulation converts the guided waves in the high-refractive-index indium-tin-oxide/organic layers into external leaky waves. We used the finite-difference time-domain method to optimize the structural parameters of the photonic crystal pattern and to analyze the microcavity effect by the metallic cathode of the OLED. With the use of an

Atomic and Molecular Physics, and OpticsPhysics and Astronomy
2
Article|284 citations·2012
Body composition and its association with cardiometabolic risk factors in the elderly: A focus on sarcopenic obesity
Ji-Youn Chung, Hee‐Taik Kang, Duk‐Chul Lee, Hye-Ree Lee, Yong‐Jae Lee
SJR Q1Archives of Gerontology and GeriatricsOA
PhysiologyMedicine
3
Article|203 citations·2020
Triglyceride glucose (TyG) index as a predictor of incident type 2 diabetes among nonobese adults: a 12-year longitudinal study of the Korean Genome and Epidemiology Study cohort
Byoungjin Park, Hye Sun Lee, Yong‐Jae Lee
SJR Q1Translational researchOA
Endocrinology, Diabetes and MetabolismMedicine
4
Review|164 citations·2018
Long-Term Exposure to Air Pollutants and Cancer Mortality: A Meta-Analysis of Cohort Studies
Hong-Bae Kim, Jae‐Yong Shim, Byoungjin Park, Yong‐Jae Lee
SJR Q2International Journal of Environmental Research and Public HealthOA

The aim of this study was to examine the relationship between main air pollutants and all cancer mortality by performing a meta-analysis. We searched PubMed, EMBASE (a biomedical and pharmacological bibliographic database of published literature produced by Elsevier), and the reference lists of other reviews until April 2018. A random-effects model was employed to analyze the meta-estimates of each pollutant. A total of 30 cohort studies were included in the final analysis. Overall risk estimate

Health, Toxicology and MutagenesisEnvironmental Science
5
Review|157 citations·2019
A Review of the Pharmacological Efficacy and Safety of Licorice Root from Corroborative Clinical Trial Findings
Yu‐Jin Kwon, Da‐Hye Son, Tae‐Ha Chung, Yong‐Jae Lee
SJR Q3Journal of Medicinal FoodOA

Since ancient times, licorice, the root of <i>Glycyrrhiza glabra</i>, has been known to have a wide spectrum of therapeutic effects. Glycyrrhizin is cleaved to glycyrrhizic acid, which is subsequently converted to glycyrrhetic acid by human intestinal microflora. Glycyrrhetic acid is a potent inhibitor of 11<i>β</i>-hydroxysteroid dehydrogenase (11<i>β</i>-HSD) and performs a range of corticosteroid-like activities. The pharmacologic effects of licorice contribute to its anti-inflammatory, antio

PharmacologyPharmacology, Toxicology and Pharmaceutics
6
Article|128 citations·2011
Relationship of neutrophil–lymphocyte ratio with arterial stiffness and coronary calcium score
Byoungjin Park, Jae‐Yong Shim, Hye-Ree Lee, Jung‐Hyun Lee, Dong‐Hyuk Jung, Hong-Bae Kim, Ha-Young Na, Yong‐Jae Lee
SJR Q1Clinica Chimica ActaOA
OncologyMedicine
7
Review|119 citations·2022
Usefulness of Complete Blood Count (CBC) to Assess Cardiovascular and Metabolic Diseases in Clinical Settings: A Comprehensive Literature Review
In‐Ho Seo, Yong‐Jae Lee
SJR Q1BiomedicinesOA

Complete blood count (CBC) is one of the most common blood tests requested by clinicians and evaluates the total numbers and characteristics of cell components in the blood. Recently, many investigations have suggested that the risk of cancer, cardiovascular disease (CVD), arteriosclerosis, type 2 diabetes (T2DM), and metabolic syndrome can be predicted using CBC components. This review introduces that white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR), hemoglobin (Hb), mean corpuscula

OncologyMedicine
8
Article|116 citations·2020
Knee osteoarthritis and its association with mental health and health‐related quality of life: A nationwide cross‐sectional study
H.C. Park, Hyung-Sik Kim, Yong‐Jae Lee
SJR Q2Geriatrics and gerontology international/Geriatrics & gerontology internationalOA

AIM: To investigate the relationship between knee osteoarthritis, mental health and health-related quality of life (QoL). METHODS: This study included 6343 men and women aged ≥50 years from the Korean National Health and Nutrition Examination Survey. Osteoarthritis was defined as Kellgren-Lawrence grade ≥2 in the knee on radiographic images with knee pain. Mental health and health-related QoL were assessed according to three dimensions (depressive mood, psychological distress and suicidal ideati

RheumatologyMedicine
9
Article|87 citations·2011
Biohydrogenation of Linolenic Acid to Stearic Acid by the Rumen Microbial Population Yields Multiple Intermediate Conjugated Diene Isomers
Yong‐Jae Lee, Thomas C. Jenkins
SJR Q1Journal of Nutrition
Nutrition and DieteticsNursing
10
Article|81 citations·2009
Association between serum uric acid and non-alcoholic fatty liver disease in Korean adults
Yong‐Jae Lee, Hye-Ree Lee, Jung‐Hyun Lee, Youn-Ho Shin, Jae‐Yong Shim
SJR Q1Clinical Chemistry and Laboratory Medicine (CCLM)OA

BACKGROUND: Increased uric acid is associated with the metabolic syndrome, conditions linked to oxidative stress and insulin resistance. Non-alcoholic fatty liver disease (NAFLD) is now considered a hepatic manifestation of insulin resistance. However, little has been written regarding the association between uric acid and NAFLD. METHODS: We examined the association between uric acid and the presence of NAFLD in 3768 Koreans (2133 men, 1635 women; aged 20-75 years) in a health examination progra

NephrologyMedicine
11
Article|76 citations·2011
The Relationship Between Arterial Stiffness and Nonalcoholic Fatty Liver Disease
Yong‐Jae Lee, Jae‐Yong Shim, Byung-Soo Moon, Youn-Ho Shin, Dong‐Hyuk Jung, Jung‐Hyun Lee, Hye-Ree Lee
SJR Q2Digestive Diseases and Sciences
EpidemiologyMedicine
12
Article|75 citations·2020
Triglyceride to HDL-cholesterol ratio and the incidence risk of type 2 diabetes in community dwelling adults: A longitudinal 12-year analysis of the Korean Genome and Epidemiology Study
T H Lim, Hye Sun Lee, Yong‐Jae Lee
SJR Q1Diabetes Research and Clinical PracticeOA
Endocrinology, Diabetes and MetabolismMedicine
13
Article|72 citations·2010
Relationship between white blood cell count and nonalcoholic fatty liver disease
Yong‐Jae Lee, Hye-Ree Lee, Jae‐Yong Shim, Byung-Soo Moon, Jung‐Hyun Lee, Jong-Koo Kim
SJR Q1Digestive and Liver DiseaseOA
EpidemiologyMedicine
14
Review|69 citations·2013
Vitamin D status and childhood health
Youn Ho Shin, Hye Jung Shin, Yong‐Jae Lee
Korean Journal of PediatricsOA

Vitamin D is an essential component of bone and mineral metabolism; its deficiency causes growth retardation and skeletal deformities in children and osteomalacia and osteoporosis in adults. Hypovitaminosis D (vitamin D insufficiency or deficiency) is observed not only in adults but also in infants, children, and adolescents. Previous studies suggest that sufficient serum vitamin D levels should be maintained in order to enhance normal calcification of the growth plate and bone mineralization. M

Pathology and Forensic MedicineMedicine
15
Article|68 citations·2018
Relationship Between Handgrip Strength and Pulmonary Function in Apparently Healthy Older Women
Da‐Hye Son, Ji Won Yoo, Mi‐Ra Cho, Yong‐Jae Lee
SJR Q1Journal of the American Geriatrics SocietyOA

OBJECTIVES: To investigate the relationship between handgrip strength and pulmonary function. DESIGN: Cross-sectional study of a representative sample of older Korean women. SETTING: The Korean National Health and Nutrition Examination Survey. PARTICIPANTS: Community-dwelling women aged 65 and older without chronic diseases or pulmonary disease (N=605). MEASUREMENTS: Handgrip strength was measured using a digital hand dynamometer, and pulmonary function was tested according to guidelines of the

PhysiologyMedicine

Research Areas

EpidemiologyMolecular BiologyOncologyEndocrinology, Diabetes and MetabolismReproductive MedicineCardiology and Cardiovascular Medicine

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