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Young-Seok Park

Seoul National University · Medicine

About the Lab

Professor Young-Seok Park's research lab specializes in surgical oncology and neurosurgical interventions, with a strong focus on improving long-term outcomes in patients with gastric cancer and cerebrovascular or epileptic disorders. The lab investigates critical factors such as body composition, sarcopenia, and postoperative nutritional status in gastric cancer patients, while also exploring genetic polymorphisms and surgical techniques in conditions like moyamoya disease and insular epilepsy. Their work integrates clinical outcomes with advanced imaging and personalized surgical strategies, particularly in minimizing postoperative complications and optimizing patient survival. The lab also examines innovative surgical techniques, such as uncinated Roux-en-Y gastrojejunostomy and endoscopic-Gamma Knife approaches for craniopharyngioma, to enhance recovery and reduce recurrence.

gastric cancersarcopeniapostoperative outcomesneurosurgical techniquescraniopharyngioma

Research Overview

Papers
443
Total Citations
8,244
Papers (5y)
114
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
114total
2022
2023
2024
2025
2026
Citations per year (5y)
1,041total
20222023202420252026

Selected Papers

15
1
Article|75 citations·2009
Clinical impact of microsatellite instability in colon cancer following adjuvant FOLFOX therapy
Seung Tae Kim, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Ho Yeong Lim, Won Ki Kang, Jin Yong Kim, Young Ho Kim, Dong Kyung Chang, Poong‐Lyul Rhee, Dae Shick Kim, Hae‐Ran Yun
SJR Q1Cancer Chemotherapy and Pharmacology
Pathology and Forensic MedicineMedicine
2
Article|60 citations·2018
Prognostic Roles of Perioperative Body Mass Index and Weight Loss in the Long-Term Survival of Gastric Cancer Patients
Young Suk Park, Do Joong Park, Yoontaek Lee, Ki Bum Park, Sa-Hong Min, Sang-Hoon Ahn, Hyung‐Ho Kim
SJR Q1Cancer Epidemiology Biomarkers & Prevention

Abstract Background: Most patients with gastric cancer rapidly lose weight after gastrectomy. Therefore, analysis of the effect of body mass index (BMI) on patients with gastric cancer survival should include postoperative BMI and BMI loss and preoperative BMI. This retrospective cohort study analyzed the effect of three BMI variables and their interaction on long-term outcomes. Methods: Preoperative BMI analysis included 2,063 patients with gastric cancer who underwent curative gastrectomy betw

Pulmonary and Respiratory MedicineMedicine
3
Article|58 citations·2012
The Role of VEGF and KDR Polymorphisms in Moyamoya Disease and Collateral Revascularization
Young Seok Park, Young Joo Jeon, Hyun‐Seok Kim, Kyu Young Chae, Seung‐Hun Oh, In Bo Han, Hyun Sook Kim, Wonchan Kim, Ok Joon Kim, Tae Gon Kim, Joong-Uhn Choi, Dong-Seok Kim
SJR Q1PLoS ONEOA

We conducted a case-control study to investigate whether vascular endothelial growth factor (VEGF -2578, -1154, -634, and 936) and kinase insert domain containing receptor (KDR -604, 1192, and 1719) polymorphisms are associated with moyamoya disease. Korean patients with moyamoya disease (n = 107, mean age, 20.9±15.9 years; 66.4% female) and 243 healthy control subjects (mean age, 23.0±16.1 years; 56.8% female) were included. The subjects were divided into pediatric and adult groups. Among the 6

RheumatologyMedicine
4
Article|47 citations·2008
Factors contributing to resectability and seizure outcomes in 44 patients with ganglioglioma
Young Seok Park, Dong-Seok Kim, Kyu‐Won Shim, Jung-Hee Kim, Joong-Uhn Choi
SJR Q2Clinical Neurology and NeurosurgeryOA
GeneticsMedicine
5
Article|43 citations·2021
Prognostic significance of surgery‐induced sarcopenia in the survival of gastric cancer patients: a sex‐specific analysis
Ja Kyung Lee, Young Suk Park, Kanghaeng Lee, Sang Il Youn, Yongjoon Won, Sa-Hong Min, Sang‐Hoon Ahn, Do Joong Park, Hyung‐Ho Kim
SJR Q1Journal of Cachexia Sarcopenia and MuscleOA

BACKGROUND: Preoperative sarcopenia is associated with a poor long-term prognosis in patients with gastric cancer (GC). Most GC patients rapidly lose muscle mass after gastrectomy. This retrospective cohort study analysed the effect of postoperative muscle loss and surgery-induced sarcopenia on the long-term outcomes of patients with GC. METHODS: Preoperative and postoperative 1 year abdominal computed tomography scans were available for 1801 GC patients who underwent curative gastrectomy betwee

PhysiologyMedicine
6
Article|43 citations·2012
Patients with idiopathic trigeminal neuralgia have a sharper-than-normal trigeminal-pontine angle and trigeminal nerve atrophy
Seung Man Ha, Sang Heum Kim, Eun Hye Yoo, Inbo Han, Dong Ah Shin, Kyung Gi Cho, Sang Sup Chung, Young Seok Park
SJR Q1Acta Neurochirurgica
Pathology and Forensic MedicineMedicine
7
Article|41 citations·2012
Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population
Young Seok Park, Young Joo Jeon, Boeun Lee, Tae Gon Kim, Joong-Uhn Choi, Dong-Seok Kim, Nam Keun Kim
SJR Q2Neuroscience LettersOA
RheumatologyMedicine
8
Article|41 citations·2009
Insular epilepsy surgery under neuronavigation guidance using depth electrode
Young Seok Park, Yun Ho Lee, Kyu‐Won Shim, Yoon Jin Lee, Heung Dong Kim, Joon Soo Lee, Dong-Seok Kim
SJR Q2Child s Nervous SystemOA

OBJECTIVES: The unfavorable surgical results that have been reported with insular epilepsy surgery may be related to inadequate monitoring. Insular epilepsy surgery requires the precise monitoring and tailored removal of the epileptic zone. The purposes of this study were to precisely monitor the hidden cortex and determine the effectiveness of using different monitoring methods, including subpial depth electrodes. MATERIALS AND METHODS: This is a study of a single center series of six patients

Psychiatry and Mental healthMedicine
9
Article|38 citations·2018
7.0 Tesla MRI tractography in patients with trigeminal neuralgia
Hyeong Cheol Moon, Soon-Tae You, Hyeon Man Baek, Young Jai Jeon, Chan-A Park, Jei Jun Cheong, Youn Joo Lee, Young Seok Park
SJR Q2Magnetic Resonance Imaging
Radiology, Nuclear Medicine and ImagingMedicine
10
Article|32 citations·2009
Recurrence rates after neuroendoscopic fenestration and Gamma Knife surgery in comparison with subtotal resection and Gamma Knife surgery for the treatment of cystic craniopharyngiomas
Young Seok Park, Jong Hee Chang, Yong Gou Park, Dong-Seok Kim
SJR Q1Journal of neurosurgeryOA

OBJECT: The object of this study was to compare the recurrence rates of cystic craniopharyngiomas after neuroendoscopic cyst fenestration combined with Gamma Knife surgery (GKS) and after subtotal resection (STR) combined with GKS. METHODS: The records of 27 patients (age range 3-66 years) with cystic craniopharyngiomas that were treated surgically or neuroendoscopically before GKS between January 2000 and December 2007 were reviewed to compare recurrence rates. The patients were divided into 2

Endocrinology, Diabetes and MetabolismMedicine
11
Article|32 citations·2017
Effect of optogenetic modulation on entopeduncular input affects thalamic discharge and behavior in an AAV2-α-synuclein-induced hemiparkinson rat model
Hyeong Cheol Moon, So-Yoon Won, Eung Gook Kim, Hyong Kyu Kim, Chul Bum Cho, Young Seok Park
SJR Q2Neuroscience Letters
NeurologyMedicine
12
Article|32 citations·2018
Roux Stasis Syndrome and Gastric Food Stasis After Laparoscopic Distal Gastrectomy with Uncut Roux‐en‐Y Reconstruction in Gastric Cancer Patients: A Propensity Score Matching Analysis
Young Suk Park, Dong Joon Shin, Sang‐Yong Son, Ki Hyun Kim, Dong Jin Park, Sang Hoon Ahn, Do Joong Park, Hyung‐Ho Kim
SJR Q1World Journal of Surgery

BACKGROUND: Uncut Roux-en-Y gastrojejunostomy (uRYGJ) was developed to prevent slow peristalsis in the Roux limb after Roux-en-Y gastrojejunostomy (RYGJ). This study compared the incidence of Roux stasis syndrome (RSS) and severe gastric food stasis in gastric cancer patients who underwent RYGJ or uRYGJ after laparoscopic curative distal gastrectomy. METHODS: Between January 2006 and June 2012, 319 patients underwent RYGJ or uRYGJ. After covariates were adjusted by propensity score matching, 39

SurgeryMedicine
13
Article|32 citations·2009
Emergency endovascular Stent graft and coil placement for internal carotid artery injury during transsphenoidal surgery
Young Seok Park, Jin Young Jung, Jung Yong Ahn, Dong Joon Kim, Sun Ho Kim
Surgical NeurologyOA
Pulmonary and Respiratory MedicineMedicine
14
Article|31 citations·2011
A Combination Procedure with Double C-Shaped Skin Incision and Dual-Floor Burr Hole Method to Prevent Skin Erosion on the Scalp and Reduce Postoperative Skin Complications in Deep Brain Stimulation
Young Seok Park, Jeong‐han Kang, Hae Yu Kim, Dong Wan Kang, Won Seok Chang, Joo Pyung Kim, Jin Woo Chang
SJR Q1Stereotactic and Functional NeurosurgeryOA

BACKGROUND: The purpose of this study was to introduce a combination procedure with double C-shaped skin incision and an adjusted dual-floor burr hole to prevent skin complications on the scalp with deep brain stimulation (DBS) surgery. METHODS: Between March 2000 and March 2010, 504 DBS electrodes were implanted in 268 patients. We included both bilateral and unilateral DBS surgery cases for Parkinson's disease, tremor, pain, obsessive-compulsive disorder and intractable seizure accompanied wit

NeurologyMedicine
15
Article|31 citations·2009
Neurocognitive and psychological profiles in pediatric arachnoid cyst
Young Seok Park, Soyong Eom, Kyu‐Won Shim, Dong-Seok Kim
SJR Q2Child s Nervous SystemOA
Cellular and Molecular NeuroscienceNeuroscience

Research Areas

Pulmonary and Respiratory MedicineSurgeryPhysiologyNeurologyRheumatologyCellular and Molecular Neuroscience

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