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Yun Soo Park

Yonsei University · Medicine

About the Lab

Professor Yun Soo Park's research lab specializes in the intersection of nanophotonics and biomedical engineering, focusing on the development of advanced optoelectronic devices and the epidemiological and clinical investigation of antimicrobial resistance. The lab explores innovative photonic crystal structures to enhance light extraction in GaN-based LEDs, contributing to next-generation lighting and display technologies. Concurrently, it investigates the molecular epidemiology, risk factors, and clinical outcomes of extended-spectrum β-lactamase (ESBL)-producing and carbapenemase-producing Enterobacteriaceae, particularly in community-onset infections, with an emphasis on antimicrobial stewardship and public health implications. The lab integrates materials science with clinical microbiology to address both technological innovation and pressing global health challenges.

photonic crystalsantimicrobial resistanceESBL-producing E. coliLEDsclinical epidemiology

Research Overview

Papers
146
Total Citations
2,282
Papers (5y)
41
Primary Field
Medicine

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
41total
2022
2023
2024
2025
2026
Citations per year (5y)
260total
20222023202420252026

Selected Papers

15
1
Article|333 citations·2005
Enhanced light extraction from GaN-based light-emitting diodes with holographically generated two-dimensional photonic crystal patterns
Dongho Kim, Chi-O Cho, Yeong-Geun Roh, Heonsu Jeon, Yoon Soo Park, Jaehee Cho, Jin Seo Im, Cheolsoo Sone, Yongjo Park, Won Jun Choi, Q‐Han Park
SJR Q1Applied Physics Letters

We observed a significant enhancement in light output from GaN-based light-emitting diodes (LEDs) in which two-dimensional photonic crystal (PC) patterns were integrated. Two-dimensional square-lattice air-hole array patterns with a period that varied from 300 to 700 nm were generated by laser holography. Unlike the commonly utilized electron-beam lithographic technique, the holographic method can make patterns over a large area with high throughput. The resultant PC-LED devices with a pattern p

Condensed Matter PhysicsPhysics and Astronomy
2
Article|298 citations·2012
Community-Associated Extended-Spectrum β-Lactamase–Producing Escherichia coli Infection in the United States
Yohei Doi, Yoon Soo Park, Jesabel I. Rivera, Jennifer Adams‐Haduch, Ameet Hingwe, Emilia Mia Sordillo, James S. Lewis, Wanita J. Howard, Laura E. Johnson, Bruce Polsky, James H. Jorgensen, Sandra S. Richter
SJR Q1Clinical Infectious DiseasesOA

Background. The occurrence of community-associated infections due to extended-spectrum β-lactamase (ESBL)-producing Escherichia coli has been recognized as a major clinical problem in Europe and other regions. Methods. We conducted a prospective observational study to examine the occurrence of community-associated infections due to ESBL-producing E. coli at centers in the United States. Five academic and community hospitals and their affiliated clinics participated in this study in 2009 and 2010

Molecular MedicineBiochemistry, Genetics and Molecular Biology
3
Article|51 citations·2009
Risk factors and clinical features of infections caused by plasmid-mediated AmpC β-lactamase-producing Enterobacteriaceae
Yoon Soo Park, Sunmi Yoo, Miran Seo, Jin Yong Kim, Yong Kyun Cho, Hyunjoo Pai
SJR Q1International Journal of Antimicrobial Agents
Molecular MedicineBiochemistry, Genetics and Molecular Biology
4
Article|42 citations·2010
Extensively drug-resistant Acinetobacter baumannii: risk factors for acquisition and prevalent OXA-type carbapenemases—a multicentre study
Yoon Soo Park, Hyukmin Lee, Kkot Sil Lee, Seung-Sik Hwang, Yong Kyun Cho, Hyo Youl Kim, Young Uh, Bum Sik Chin, Sang Hoon Han, Seok Hoon Jeong, Kyungwon Lee, June Myung Kim
SJR Q1International Journal of Antimicrobial AgentsOA
Molecular MedicineBiochemistry, Genetics and Molecular Biology
5
Article|40 citations·2020
Patterns of viral clearance in the natural course of asymptomatic COVID-19: Comparison with symptomatic non-severe COVID-19
Jae‐Sun Uhm, Jin Young Ahn, Jong Hoon Hyun, Yujin Sohn, Jung Ho Kim, Su Jin Jeong, Nam Su Ku, Jun Yong Choi, Yu-Kyung Park, Yu-Kyung Park, Ho-sung Yi, Sung Kyu Park
SJR Q1International Journal of Infectious DiseasesOA

OBJECTIVES: The aim of this study was to elucidate patterns of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) clearance in the natural course of asymptomatic coronavirus disease 2019 (COVID-19). METHODS: Consecutive patients with non-severe COVID-19 were included retrospectively. Asymptomatic patients with a normal body temperature and no evidence of pneumonia throughout the disease course were assigned to the asymptomatic group. The reverse transcription PCR (RT-PCR) assay was rep

Infectious DiseasesMedicine
6
Article|38 citations·2012
Clinical and Microbiologic Characteristics of Cephalosporin-Resistant Escherichia coli at Three Centers in the United States
Yoon Soo Park, Jennifer Adams‐Haduch, Kathleen A. Shutt, Daniel M. Yarabinec, Laura E. Johnson, Ameet Hingwe, James S. Lewis, James H. Jorgensen, Yohei Doi
SJR Q1Antimicrobial Agents and ChemotherapyOA

We investigated the clinical and microbiologic features of 300 cases of cephalosporin-resistant Escherichia coli producing extended-spectrum β-lactamase (ESBL) or plasmid-mediated AmpC β-lactamase (pAmpC) at three medical centers in the United States. Solid-organ malignancy, connective tissue disease, and a recent history of surgery were more common among pAmpC-producing cases (n = 49), whereas urinary catheter at enrollment, diabetes, and hospitalization in the past year were more common among

Molecular MedicineBiochemistry, Genetics and Molecular Biology
7
Article|37 citations·2018
Changes in Antimicrobial Usage Patterns in Korea: 12-Year Analysis Based on Database of the National Health Insurance Service-National Sample Cohort
Young Ah Kim, Yoon Soo Park, Taemi Youk, Hyukmin Lee, Kyungwon Lee
SJR Q1Scientific ReportsOA

National antimicrobial usage and prescription patterns during the 12 years from 2002 to 2013 were analyzed using the National Health Insurance Service-National Sample Cohort. Antimicrobial usage was analyzed by major illness, sex, age, area of residence, income rank, diagnosis, and type of medical institution for each year. Total antimicrobial prescriptions increased from 15.943 daily defined dose (DDD)/1,000 inhabitants/day in 2002 to 24.219 in 2013. In 2013, 72% of total prescriptions were adm

Applied Microbiology and BiotechnologyImmunology and Microbiology
8
Article|32 citations·2020
Risk Factors for Carbapenemase-Producing Enterobacterales Infection or Colonization in a Korean Intensive Care Unit: A Case–Control Study
Young Ah Kim, Se Ju Lee, Yoon Soo Park, Yeo Jin Lee, Jeong Hwa Yeon, Young Hee Seo, Kyungwon Lee
SJR Q1AntibioticsOA

The purpose of this study is to identify the factors related to the infection and/or colonization of carbapenemase-producing Enterobacterales (CPE) based on clinical and microbiological data for patients in the intensive care unit (ICU). All patients admitted to medical ICU were screened for CPE on admission and weekly, and this 1:2 case–control study included patients with CPE identified by screening or clinical cultures from 2017 to 2018. The clonal relatedness was evaluated by pulsed-field ge

Molecular MedicineBiochemistry, Genetics and Molecular Biology
9
Article|31 citations·2014
Risk Factors and Molecular Epidemiology of Community-Onset Extended-Spectrum β-Lactamase-ProducingEscherichia coliBacteremia
Yoon Soo Park, Il Kwon Bae, Juwon Kim, Seok Hoon Jeong, Seung-Sik Hwang, Yiel-Hea Seo, Yong Kyun Cho, Kyungwon Lee, June Myung Kim
SJR Q2Yonsei Medical JournalOA

The most common types of ESBLs in E. coli causing community-onset bacteremia were CTX-M-15 and CTX-M-14 in Korea. By result of decision tree analysis, the empirical use of carbapenems is suggested only for patients with severe sepsis/septic shock, hepatobiliary infection, or healthcare-associated urinary tract infection.

Molecular MedicineBiochemistry, Genetics and Molecular Biology
10
Article|28 citations·2004
Clinical Outcomes of Tuberculosis in Renal Transplant Recipients
Yoon Soo Park, Jun Yong Choi, Cheong Ho Cho, Kyung Hee Chang, Young Goo Song, Yu Seun Kim, June Myung Kim
SJR Q2Yonsei Medical JournalOA

Tuberculosis (TB) is an important cause of morbidity and mortality in renal transplant recipients. Rifampin has a potent sterilizing activity, but it reduces the serum concentrations of the immunosuppressive agents. Moreover, the possible contribution made by mycobacterial infection to the incidence of graft rejection or renal dysfunction remains unclear. In this study, we investigated the recurrence of TB and graft survival duration according to rifampin usage, and we evaluated the factors that

EpidemiologyMedicine
11
Article|28 citations·2018
Trends in South Korean antimicrobial use and association with changes in Escherichia coli resistance rates: 12-year ecological study using a nationwide surveillance and antimicrobial prescription database
Young Ah Kim, Yoon Soo Park, Taemi Youk, Hyukmin Lee, Kyungwon Lee
SJR Q1PLoS ONEOA

The purpose of this study is to determine the correlation between use of antimicrobials, such as fluoroquinolone, cefoxitin, and cefotaxime, and Escherichia coli resistance using a nationwide database. Nationwide data on antimicrobial consumption for 12 years (2002 to 2013) were acquired from a database of subjects (n = 1,025,340) included in the National Health Insurance Service-National Sample Cohort. National antimicrobial resistance rates of E. coli were obtained from the Korean Antimicrobia

Molecular MedicineBiochemistry, Genetics and Molecular Biology
12
Article|17 citations·2008
Pseudooutbreak of Stenotrophomonas maltophilia bacteremia in a general ward
Yoon Soo Park, Sue-Yun Kim, Shin Young Park, Ji-Hea Kang, Hee Seung Lee, Yiel-Hae Seo, Yong Kyun Cho
SJR Q1American Journal of Infection Control
EndocrinologyBiochemistry, Genetics and Molecular Biology
13
Article|14 citations·2019
Risk factors of community-onset extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteraemia in South Korea using national health insurance claims data
Yongseop Lee, Young Ah Kim, Dokyun Kim, Jong Hee Shin, Young Uh, Kyeong Seob Shin, Jeong Hwan Shin, Seok Hoon Jeong, Yoon Soo Park
SJR Q1International Journal of Antimicrobial AgentsOA
Molecular MedicineBiochemistry, Genetics and Molecular Biology
14
Article|14 citations·2004
Clinical Outcomes of Tuberculosis in Renal Transplant Recipients
박윤수, 최준용, 조정호, 장경희, 송영구, 김유선, 김준명
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120040450050865

Tuberculosis (TB) is an important cause of morbidity and mortality in renal transplant recipients. Rifampin has a potent sterilizing activity, but it reduces the serum concentrations of the immunosuppressive agents. Moreover, the possible contribution made by mycobacterial infection to the incidence of graft rejection or renal dysfunction remains unclear. In this study, we investigated the recurrence of TB and graft survival duration according to rifampin usage, and we evaluated the factors that

15
letter|11 citations·2012
Escherichia coliProducing CMY-2 β-Lactamase in Retail Chicken, Pittsburgh, Pennsylvania, USA
Yoon Soo Park, Jennifer Adams‐Haduch, Jesabel I. Rivera, Scott Curry, Lee H. Harrison, Yohei Doi
SJR Q1Emerging infectious diseasesOA

To the Editor: Rates of resistance to various antimicrobial drugs are rapidly increasing in Escherichia coli, not only in health care settings but also in the community. The food supply is suspected as a potential source of antimicrobial-resistant E. coli strains, which include cephalosporin-resistant E. coli found in retail meat products and other types of food (1).

Molecular MedicineBiochemistry, Genetics and Molecular Biology

Research Areas

Infectious DiseasesMolecular MedicineEpidemiologyEndocrinologyApplied Microbiology and BiotechnologyMicrobiology

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