Yunwoo Ko

Objectives. The aims of this study were to evaluate the prevalence of otolaryngologic diseases in Korea. Methods. We obtained data from the 2008 Korea National Health and Nutrition Examination Surveys (KNHANES), which were cross-sectional surveys of the civilian, non-institutionalized population of South Korea (n=4,930). A field survey team that included an otolaryngologist, nurses, and interviewers moved with a mobile examination unit and performed otolaryngologic interviews and physical examin

Purpose: Although follicular thyroid cancer (FTC) has a relatively fair prognosis, distant metastasis sometimes results in poorprognosis and survival. There is little understanding of the mechanisms contributing to the aggressiveness potential of thyroidcancer. We showed that hypoxia inducible factor-1α (HIF-1α) induced aggressiveness in FTC cells and identified the underlyingmechanism of the HIF-1α-induced invasive characteristics. Materials and Methods: Cells were cultured under controlled hyp

Objectives. These days, the main injection laryngoplasty technique is cricothyroid (CT) approach. However, patients who have previously undergone other neck treatments, such as thyroidectomy or neck dissection have distorted anatomical landmark makes this approach more difficult. The aim of this study is to determined the efficiency of transcartilaginous (TC) approah as compared with CT approach for unilateral vocal fold paralysis patients, especially for previously neck treated patients. Method

Purpose: To examine the feasibility of endoscopic thyroidectomy (ET) via an axillo-breast approach without gas insufflation for large thyroid tumors and micropapillary carcinomas. Materials and Methods: The patients in the benign group were separated into groups 1 (n=95, <4 cm in tumor diameter) and 2 (n=37, ≥4 cm in tumor diameter). Also, 57 patients in the micropapillary carcinoma group underwent an endoscopic hemithyroidectomy (HT) (group 3) and were compared with 60 patients who received con

Purpose: The treatment of a clinically node-positive (cN+) neck is important in the management of oral cavity squamous cell carcinoma (OSCC). However, the extent of neck dissection (ND) remains controversial. The purpose of our study was to evaluate whether level IV or V can be excluded in therapeutic ND for cN+ OSCC patients. Materials and Methods: We performed a retrospective chart review of 92 patients who underwent a comprehensive or selective ND as a therapeutic treatment of cN+ OSCC from J

Purpose: We hypothesized that comprehensive neck dissection could be achieved via a gasless transaxillary approach using a robotic system. We intended to evaluate the accessibility of level I, IIB and VA nodes with transaxillary robot-assisted neck dissection of four cadavers. Materials and Methods: Transaxillary robotic neck dissection was performed in four cadavers through a 7-cm longitudinal incision at the anterior axilla and a 0.8-cm-sized incision in the chest wall. Results: We successfull

Purpose: The fourth state of matter, plasma is known as an ionized gas with electrons, radicals and ions. The use of non-thermal plasma (NTP) in cancer research became possible because of the progresses in plasma medicine. Previous studies on the potentialNTP-mediated cancer therapy have mainly concentrated on cancer cell apoptosis. In the present study, we compared the inhibitoryeffect of NTP on cell migration and invasion in the oral squamous cancer cell lines. Materials and Methods: We used o

공유차 서비스와 수요대응형 대중교통은 어플리케이션 기반의 온디맨드 모빌리티 서비스로, 승용차 의존도와 도로 면적 점유율 감소를 이끌어내는 지속 가능한 교통수단이다. 그러나 교통 정체가 심각하여 천문학적인 사회적 비용이 발생하는 수도권 통근 상황에서 온디맨드 서비스의 역할을 탐색하는 연구는 부족한 실정이다. 본 연구는 수도권 통근 상황에서 온디맨드 서비스 선호도를 알아보고자 하였다. 이를 위해 현재 통근 실태를 기반으로 승용차, 택시, 대중교통 3개의 기존 교통수단과 편도 공유차 서비스, 왕복 공유차 서비스, 수요대응형 대중교통 3개의 온디맨드 모빌리티 서비스 중 가장 선호하는 수단 하나를 선택하는 피벗 잠재선호 조사를 설계하였다. 가상의 잠재선호 실험은 직교배열법(Orthogonal design)을 사용하여 설계하였다. 그 결과, 54개의 가상 선택상황이 생성되었으며 이를 9개의 구역으로 분할하였다. 응답자는 임의의 하나의 구역의 6개의 선택상황에 응답하였다. 560명의 응답자가 6

Purpose: The aim of this study was to compare the surgical completeness and outcome of total thyroidectomy in two patient groups: One treated by harmonic scalpel (HS) and one by conventional total thyroidectomy (CT). Methods: Between March 2006 and December 2007, 104 patients had total thyroidectomy by HS and 108 patients underwent CT. We analyzed clinicopathological characteristics and stimulated serum thyroid-stimulating hormone (TSH), thyroglobulin (Tg), and anti-Tg antibodies at the time of

Purpose: Acute side effects of radiation such as oral mucositis are observed in most patients. Although several potential radioprotective agents have been proposed,no effective agent has yet been identified. In this study, we investigated the effectiveness of synthetic compound 3-amino-3-(4-fluoro-phenyl)-1H-quinoline-2,4-dione (KR22332) as a radioprotective agent. Materials and Methods: Cell viability,apoptosis, the generation of reactive oxygen species (ROS), mitochondrial membrane potential c

Purpose: Robotic head and neck surgery is widespread nowadays. However, in the reconstruction field, the use of robotic opera tions is not. This article aimed to examine methodologies for conventional head and neck reconstruction after robotic tumor sur gery in an effort to obtain further options for future reconstruction manipulations. Materials and Methods: A retrospective review of all patients who received head and neck robot surgery and conventional recon structive surgery between October 2

Thyroglossal duct carcinoma is uncommon, occurring in approximately 1% of all thyroglossal duct remnants. This rare neo- plasm is characterized by relatively nonaggressive behavior with infrequent lymph nodal spread. Another rare neoplasm of the head and neck region is a carotid body tumor. A 78-year-old woman with a 3-year history of midline and bilateral neck masses was referred to us. Fine needle aspiration biopsies and a computed tomography scan suggested the diagnosis of thy- roglossal duct

Thyroid cancer is the most common malignancy in Korea; in 2012, about 44,000 new cases (19.6% of all malignancies) were registered and the estimated age-standardized incidence rate of thyroid cancer was 73.6 per 100,000 (17.3 and 88.6 per 100,000 in men and women, respectively). Despite the steep increase in its incidence, the agestandardized mortality rate of thyroid cancer has remained stable and 10-year relative survival rate is 99.2%. Increased detection using high-resolution ultrasonography