Ewha Womans University · Medicine
Professor Byung-Ho Yoon's research lab specializes in the design and fabrication of advanced porous ceramics, with a focus on freeze-casting techniques using camphene as a template. The lab develops highly aligned, hierarchical porous structures—particularly silicon carbide (SiC) and hydroxyapatite-based ceramics—tailored for biomedical applications such as bone tissue engineering and for structural or functional materials in extreme environments. Key innovations include in situ growth of SiC nanowires via vapor–liquid–solid mechanisms and the creation of large, interconnected pore channels (>100 μm) to enhance cellular infiltration and tissue ingrowth. The lab also explores the biological implications of materials in clinical contexts, such as the impact of thyroid hormone suppression therapy on bone mineral density in postmenopausal patients with differentiated thyroid cancer.
Figures are computed from collected data and may differ slightly.
We fabricated highly aligned porous silicon carbide (SiC) ceramics with well‐defined pore structures by freezing a polycarbosilane (PCS)/camphene solution. In this method, the solution prepared at 60°C was cast into a mold at temperatures ranging from 20° to −196°C, which resulted in a bicontinuous structure, in which each phase (camphene or PCS) was interconnected in a regular pattern. After the removal of the frozen camphene network, the samples showed highly porous structures, in which long s
The present study reports an innovative way to produce large pore channels with a size >100 μm for applications in bone tissue engineering using the camphene‐based freeze casting method, and using an unusually high freezing temperature, which is close to the solidification temperature of the slurry, in order to allow the formation of excessively overgrown camphene dendrites due to the extremely low solidification velocity. To accomplish this, hydroxyapatite (HA)/slurries with various solid lo
We fabricated highly aligned porous silicon carbide (SiC) ceramics decorated with SiC nanowires by the unidirectional freeze casting of SiC/camphene slurries with various polycarbosilane (PCS) contents, ranging from 0 to 20 wt% in relation to the SiC powders, in which the PCS preceramic was used as a binder and source for the in situ growth of the SiC nanowires. In this method, aligned pore channels were formed as a replica of the unidirectionally grown camphene dendrites, while SiC nanowires we
Although the included studies were limited by small numbers, results suggested possible association between chronic TSH suppression therapy and the lower BMD of spine and total hip in postmenopausal women (but not in premenopausal women and men) with DTC. A large, well-designed study with long-term follow-up would provide further insight into the influence of TSH suppression therapy and loss of BMD.
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