东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Motohide Uemura's research lab focuses on molecular oncology, particularly the mechanisms underlying hormone-refractory and castration-resistant prostate cancer (CRPC). The lab investigates tumor microenvironment interactions, steroid metabolism, and the role of exosomes in cancer progression and metastasis. Using advanced technologies such as cDNA microarray analysis, proteomics, and serum exosome isolation, the lab identifies novel therapeutic targets and biomarkers for advanced prostate cancer and renal cell carcinoma.
Professor Sreekanth Kumar Mallineni's research lab focuses on advancing dental materials and infection control in clinical dentistry, with a strong emphasis on biocompatibility, nanotechnology, and patient safety. The lab investigates the application of silver nanoparticles in preventing microbial biofilms and enhancing material durability, while also exploring clinical challenges related to special-needs patients and emerging infectious diseases like COVID-19. Research directions include improving diagnostic and therapeutic approaches in oral health, particularly for vulnerable populations such as children and medically compromised individuals.
Professor Gota Kikugawa's research lab specializes in molecular simulation and materials modeling, with a focus on understanding thermal transport, interfacial phenomena, and polymer cross-linking processes at the atomic scale. The lab employs advanced simulation techniques—particularly molecular dynamics (MD) and dissipative particle dynamics (DPD)—to investigate heat conduction in polymers, self-assembled monolayers, and thermoset resins, with applications in advanced composites and nanomaterials. A key emphasis is placed on developing and applying high-performance computing tools, such as specialized MD hardware (e.g., MDGRAPE-3), to enable large-scale, accurate simulations under realistic conditions like periodic boundary conditions and complex reaction kinetics. The lab also pioneers innovative simulation algorithms that integrate both geometric and kinetic criteria to model chemical reactions more realistically, especially in curing processes of epoxy and thermoset resins.
Professor Shikhar Verma's research lab specializes in next-generation wireless communication systems, with a strong focus on the Internet of Things (IoT), high-throughput wireless networks (such as Wi-Fi 7 and 5G/6G), and intelligent radio environments. The lab investigates advanced networking protocols, real-time analytics for massive IoT data, and secure, efficient communication in resource-constrained environments. It also explores innovative physical-layer techniques like Hybrid Intelligent Reflecting/Refracting Surfaces (HIRS) for millimeter-wave and sub-THz communications to enhance spectral efficiency and coverage.
Professor Shintaro Minagawa's research lab specializes in foundational aspects of quantum information theory and thermodynamics, focusing on the interplay between information processing, quantum measurement, and thermodynamic principles. The lab investigates quantum error mitigation, operational derivations of entropy, and the second laws of information thermodynamics, particularly in the context of Maxwell’s Demon and quantum feedback protocols. It also explores information-theoretic frameworks beyond quantum theory, including one-shot capacities and relative entropy in general probabilistic theories. The lab emphasizes operational and axiomatic approaches to derive physical laws from fundamental principles such as repeatability and reversibility.
Professor Ken Kondo's research lab specializes in cryospheric and glaciological processes, focusing on the impacts of climate change on glacier runoff, ice mass loss, and their environmental and societal consequences. The lab investigates the physical mechanisms driving glacier retreat and increased meltwater discharge in polar and alpine regions, particularly in Greenland and Antarctica, using remote sensing, field observations, and numerical modeling. A key focus is understanding the role of atmospheric conditions, such as temperature and wind, in amplifying melt events and their implications for sea-level rise and coastal hazards. The lab also examines the effects of light-absorbing particles, like black carbon, on glacier surface melting and ice albedo reduction.
Professor Weiren Cheng's research lab specializes in the design, synthesis, and in-depth mechanistic investigation of advanced electrocatalysts for sustainable energy conversion and storage technologies. The lab focuses on developing non-precious metal-based electrocatalysts—particularly metal-organic frameworks (MOFs), single-atom catalysts, and nanostructured oxides—engineered with precise atomic and nanoarchitectural control to enhance activity, stability, and selectivity in oxygen evolution (OER) and reduction (ORR) reactions. By integrating operando characterization techniques such as XAFS and synchrotron-based spectroscopies, the lab uncovers dynamic structural evolutions at solid-liquid interfaces, providing fundamental insights that guide the rational design of next-generation electrocatalysts. Their work bridges materials synthesis, electrochemistry, and in situ characterization to advance clean energy applications.
Professor Keitaro Kubo's research lab specializes in the biomechanics and physiology of human muscle-tendon structures, with a focus on in vivo assessment of tendon viscoelasticity and stiffness using ultrasonography. The lab investigates how various resistance, stretching, and plyometric training protocols influence the mechanical properties of tendons and their contribution to athletic performance, particularly in jumping and strength gains. A central theme is understanding the relationship between tendon structure, muscle-tendon complex stiffness, and neuromuscular function in healthy individuals and trained athletes. The lab combines advanced imaging techniques with biomechanical measurements to quantify changes in tendon elasticity and force transmission.
Professor Hidehiro Yoshida's research lab specializes in the development and processing of advanced ceramic materials, with a primary focus on high-performance oxide ceramics such as spinel, alumina, and yttria. The lab investigates innovative sintering techniques—particularly flash sintering and spark plasma sintering (SPS)—to achieve dense, nanocrystalline ceramics at significantly reduced temperatures and times. Key research directions include grain boundary engineering through rare-earth and transition metal doping to enhance creep resistance and diffusion control, as well as the fundamental understanding of defect chemistry and ionic transport in polycrystalline oxides. The lab combines experimental materials science with advanced characterization techniques and first-principles calculations to design ceramics with superior high-temperature stability and mechanical properties.
Professor Kazuki Shibanuma's research lab specializes in multiscale materials modeling with a focus on predicting the mechanical behavior of metallic materials, particularly steels, under complex loading conditions. The lab develops advanced computational models that bridge microstructural features—such as grain boundaries, phase distribution, and heterogeneous microstructures—with macroscopic fracture and fatigue performance. Key research directions include ductile and cleavage fracture mechanisms, fatigue life prediction in welded joints, and the effects of microstructure evolution on material toughness and reliability. The lab uniquely combines experimental validation with innovative modeling strategies to address real-world engineering challenges in structural materials.
Professor Sumito Ogawa's research lab focuses on molecular mechanisms underlying age-related diseases, with a particular emphasis on the roles of nuclear receptors, transcriptional regulation, and hormonal signaling in sarcopenia and cognitive decline. The lab investigates novel estrogen receptor isoforms, such as ERbetacx, and their functional implications in human physiology and pathology, as well as the involvement of corepressor complexes like NCoR/SMRT in transcriptional control relevant to aging and inflammation. Current research also explores the impact of lifestyle and nutritional factors on neurodegenerative processes and muscle function in aging. The lab integrates molecular biology, cell biology, and translational approaches to uncover therapeutic targets for age-related disorders.
Professor Rodolfo T. Gonçalves's research lab specializes in fluid-structure interaction phenomena in offshore and floating renewable energy systems, with a strong focus on vortex-induced motion (VIM), flow-induced motions (FIM), and the dynamic response of floating offshore wind turbines (FOWTs). The lab conducts experimental and numerical investigations using wave tank testing and advanced signal analysis techniques—such as the Hilbert–Huang transform—to understand nonlinear dynamics, structural flexibility, and fatigue performance of floating platforms. Research directions include the development of cost-effective, lightweight floating wind turbine concepts, particularly those using guyed towers and multi-column semisubmersible designs, and their response under wave and current loading conditions.
Professor Ichio Shimada's research lab specializes in structural and dynamic studies of membrane proteins, particularly G-protein-coupled receptors (GPCRs), using advanced solid-state and in-cell NMR spectroscopy. The lab focuses on understanding the conformational equilibria and signaling mechanisms of GPCRs in lipid environments, with an emphasis on biased signaling, receptor activation, and ligand interactions. By developing innovative NMR techniques—such as deuteration strategies and bioreactor-based in-cell NMR—the lab enables high-resolution analysis of GPCRs in near-physiological conditions, advancing drug discovery and structural biology.
Professor A. Simionescu's research lab specializes in high-energy astrophysics, focusing on the thermodynamic and chemical properties of the hot intracluster medium (ICM) in galaxy clusters. Using deep X-ray observations from missions such as Suzaku, XMM-Newton, and ROSAT, the lab investigates the spatially resolved temperature, metal abundances, and gas clumping in clusters across a range of environments—from cool-core systems like Hydra A and M87 to non-cool core clusters like Coma and Virgo. A key focus is understanding non-thermal processes such as turbulence, magnetic field suppression of thermal conduction, and large-scale motions driven by minor mergers, often using advanced spectral modeling techniques like the Gaussian-EM distribution model. The lab also contributes to cosmological constraints by measuring baryon fractions and cluster mass profiles with high precision.
Professor Kozo Tomita's research lab specializes in RNA biology and enzymology, focusing on the molecular mechanisms of RNA processing, modification, and function. Key research directions include the structural and functional analysis of RNA-modifying enzymes such as CCA-adding enzymes and METTL16, the role of tRNA modifications in translation fidelity, and the enzymatic mechanisms of viral and bacterial RNA polymerases. The lab integrates structural biology, biochemistry, and molecular genetics to uncover fundamental principles of RNA metabolism in diverse organisms, from bacteria to mitochondria and viruses.
Professor Tsuyoshi Nishikawa's research lab specializes in the development of novel polymerization methodologies and functional polymers with tailored optical, electronic, and stimuli-responsive properties. The lab focuses on designing and synthesizing advanced monomers—particularly those incorporating boron-containing functionalities—enabling access to polymers and copolymers that are difficult to prepare by conventional methods. Key research directions include radical polymerization of unconventional monomers, controlled degradation of polymer backbones via boron-based triggers, and the creation of chiral and circularly polarized luminescent materials. The work integrates synthetic polymer chemistry with computational studies (DFT) and applications in smart materials and responsive systems.
Professor Hisashi Endo's research lab specializes in marine microbial ecology, focusing on the community dynamics, physiological responses, and ecological roles of key phytoplankton groups—particularly diatoms and haptophytes—in marine ecosystems. The lab employs advanced molecular techniques such as next-generation sequencing (NGS), metabarcoding, and qPCR to investigate how environmental factors like iron availability, CO2 levels, and oceanographic conditions shape phytoplankton community structure and function across diverse oceanic regions, including the Pacific Ocean, the Kuroshio Current, and the Oyashio region. A central theme of the lab’s work is understanding the mechanisms underlying phytoplankton community stability, carbon cycling, and responses to global change drivers such as ocean acidification and nutrient limitation.
Professor Yuki Kitazumi's research lab specializes in bioelectrochemistry, focusing on direct electron transfer (DET)-type bioelectrocatalysis using redox enzymes and nanostructured electrodes. The lab investigates the interplay between enzyme structure, electrode nanoarchitecture, and electron transfer kinetics, with applications in biosensors and bioenergy conversion. A key research direction involves protein engineering of enzymes to enhance DET efficiency and enable novel catalytic functions, such as switching from oxidation to reduction under specific conditions. The lab also explores interfacial electrochemistry at liquid-liquid interfaces to understand the fundamental behavior of surface-active ions and their interactions with electric fields.
Professor Takayuki Kato's research lab specializes in structural biology, with a focus on high-resolution cryo-electron microscopy (cryoEM) to unravel the atomic-level architecture of complex biological nanostructures. The lab investigates bacterial flagella, including the basal body, hook, and filament, to understand their mechanical and dynamic properties at near-atomic resolution. A key research direction involves applying advanced cryoEM techniques to visualize the self-assembly and functional mechanisms of macromolecular machines in bacteria such as *Salmonella enterica* serovar Typhimurium. The lab also pioneers structural studies of DNA nanostructures, demonstrating the power of cryoEM for determining absolute stereochemistry and 3D architecture at unprecedented resolution.
Professor Jacqueline Urakami's research lab focuses on human-centered design and interaction in emerging technologies, with a strong emphasis on nonverbal communication, empathy in human-robot interaction, and combating misinformation through intelligent, metacognitive tools. The lab explores how sensory and emotional cues can be integrated into robotic and digital systems to enhance natural, intuitive, and inclusive human interactions. It also investigates the use of serious games and remote longitudinal methods for accessible cognitive assessment, particularly in diverse and international contexts.
