东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Toshihira Irisawa's research lab specializes in advanced composite materials, with a primary focus on carbon fiber-reinforced thermoplastics (CFRTPs) and the development of high-performance fiber-reinforced polymer systems. The lab investigates mechanical, tribological, and thermal properties of these materials, emphasizing interfacial adhesion, wear resistance, and sustainable recycling of carbon fibers. A key research direction involves the reuse of recycled carbon fibers in new composite applications, including conductive c/c composites via carbonization and graphitization processes. The lab also explores the role of various nanofillers—such as carbon nanotubes, vapor-grown carbon fibers, and ceramic particles—in enhancing the multifunctional performance of polymer fibers.
Professor Tomoyoshi Takenaka's research lab focuses on translational oncology in non-small cell lung cancer (NSCLC), with a strong emphasis on biomarkers for treatment response and prognosis. The lab investigates DNA repair enzyme expression, EGFR mutation status, and metabolic activity (e.g., FDG-PET SUVmax) to predict chemosensitivity and therapeutic outcomes. Key research directions include identifying biological predictors of response to targeted therapies and chemotherapy, as well as exploring the role of tumor microenvironment markers such as Ki-67 and VEGF. The lab also examines clinical factors influencing recurrence and postoperative complications, particularly in relation to smoking history and treatment strategies.
Professor Shigeto Yamasaki's research lab specializes in the development and characterization of advanced high-temperature structural materials, with a focus on heat-resistant alloys and steels for extreme environments. The lab investigates microstructure-property relationships in materials such as aluminum, nickel-based, and ferritic heat-resistant steels produced via additive manufacturing or advanced processing techniques. Key research directions include creep deformation mechanisms, dislocation evolution, and the role of precipitates and solute elements (e.g., nitrogen, iron, silicon) in enhancing high-temperature strength and stability. The lab employs advanced characterization techniques such as electron backscatter diffraction (EBSD), serial sectioning with electron channeling contrast imaging (ECCI), and 3D dislocation reconstruction to understand deformation and fracture at the microscale.
Professor Ahmed M.S. Mohammed’s research lab specializes in urban dynamics, focusing on the interplay between universities and their surrounding cities. The lab investigates how university campuses—particularly through their spatial configuration, openness, and location—influence urban growth, land use transformation, and socio-spatial patterns. Using advanced methodologies such as space syntax, GIS-based urbanity modeling, and agent-based simulation, the lab explores the spatiotemporal impacts of university expansion on urban development, with a strong emphasis on Fukuoka City and Kyushu University as case studies. The lab also examines citizen participation in urban safety and public space stewardship, particularly in addressing urban vandalism like graffiti.
Professor Kenichi Goushi's research lab specializes in organic optoelectronics, with a focus on the fundamental photophysics of emissive materials and their applications in next-generation light-emitting devices. The lab investigates exciton dynamics, energy transfer processes, and delayed fluorescence mechanisms in organic semiconductors, particularly in phosphorescent iridium complexes, exciplexes, and halogen-bonded cocrystals. A key research direction involves enhancing electroluminescence efficiency through advanced host-guest systems and thermally activated delayed fluorescence (TADF) emitters, aiming to overcome limitations in organic solid-state lasers and light-emitting diodes. The lab also explores fluorescence blinking in quantum dots using nonlinear optical models and anharmonic potential theories.
Professor Sumito Matoba's research lab specializes in polar atmospheric and cryospheric sciences, focusing on the interactions between sea ice, snowpack, and atmospheric chemistry in the Arctic. Key research directions include the chemical and physical processes in frost flowers, brine, and aerosols; ice core paleoclimatology to reconstruct past climate conditions; and the surface energy balance and snowpack evolution under abrupt climate change. The lab integrates field observations, in-situ measurements, and numerical modeling to understand climate feedback mechanisms in the Arctic.
Professor Kousuke Noda's research lab focuses on the molecular mechanisms underlying ocular microvascular diseases, particularly diabetic retinopathy, age-related macular degeneration, and the role of inflammation in disease progression. The lab investigates key molecules such as MMPs, MT1-MMP, VAP-1, and adhesion molecules in vascular remodeling and leukocyte recruitment. Using innovative animal models—including spontaneous models of type 2 diabetes and metabolic syndrome—the lab aims to elucidate disease pathogenesis and identify novel therapeutic targets. A central theme is the interplay between chronic inflammation, extracellular matrix remodeling, and angiogenesis in the retina and choroid.
Professor Masahiko Watanabe's research lab specializes in molecular and cellular neuroscience, focusing on the subcellular organization and functional roles of neurotransmitter receptors and signaling molecules in the mammalian brain. The lab investigates the developmental and regional expression patterns of NMDA receptor subunits, endocannabinoid system components such as 2-AG and DAGLα, and the anatomical basis of cholinergic signaling, particularly muscarinic M1 receptors. Using advanced techniques like in situ hybridization, immunofluorescence, and immunoelectron microscopy, the lab elucidates the cellular mechanisms underlying synaptic transmission and neuromodulation in key brain regions including the cerebellum, forebrain, and hippocampus. Their work provides critical insights into the structural and functional diversity of neural circuits underlying cognition, behavior, and brain development.
Professor Koji Yamazaki's research lab specializes in microbial ecology and molecular microbiology, with a focus on thermophilic and acidophilic bacteria, particularly *Alicyclobacillus acidoterrestris*, a major spoilage organism in acidic beverages. The lab investigates the molecular mechanisms of bacterial heat resistance, bacteriocin activity, and rapid detection methods using molecular techniques such as RT-PCR and 16S rRNA gene sequencing. Research also extends to environmental microbiology, including the impact of stratospheric quasi-biennial oscillations on atmospheric dynamics, linking microbial and atmospheric processes through interdisciplinary approaches.
Professor Victor Parque's research lab specializes in the mathematical and computational foundations of graph representations, optimization, and control systems. The lab focuses on developing succinct, canonical, and efficient encodings for labeled graphs—particularly directed and loopy graphs—enabling applications in machine learning, network topology optimization, and autonomous systems. A key research direction involves leveraging evolutionary computation, such as Differential Evolution, for path planning and control system tuning, especially in mobile robotics and PID controller optimization under tight computational constraints. The lab also explores minimal-length tree layouts in polygonal environments, contributing to efficient networked system design across multi-agent and distributed frameworks.
Professor Seung-Taek Lim's research lab focuses on the intersection of physical activity, metabolic health, and aging, with a particular emphasis on how lifestyle factors such as exercise, sleep patterns, and chronotype influence metabolic syndrome, insulin sensitivity, and age-related functional decline. The lab investigates the molecular and physiological mechanisms underlying sarcopenia, β-cell dysfunction, and adipose tissue metabolism, especially in pre-diabetic and elderly populations. Key research directions include the impact of resistance and aerobic exercise on cognitive reserve, lipolysis, and body composition, as well as genetic factors such as COL5A1 polymorphisms in relation to physical performance and metabolic health in Asian populations.
Professor Milad Delfan Azari's research lab specializes in theoretical and computational astrophysics, focusing on the role of neutrinos in core-collapse supernovae. The lab investigates fast neutrino flavor conversions, neutrino transport, and their impact on supernova explosion mechanisms using advanced, self-consistent Boltzmann simulations. Key research directions include the dynamics of neutrino flavor transitions, energy-dependent neutrino interactions, and the influence of neutrino collective effects on shock wave evolution and energy deposition. The lab integrates realistic astrophysical conditions from hydrodynamic simulations to explore how neutrino behavior shapes supernova outcomes.
Professor Katsunori Masaki's research lab focuses on digital health interventions for chronic disease management, particularly digital therapies for smoking cessation using smartphone applications and mobile monitoring tools. The lab also investigates respiratory and immune-mediated diseases, including the impact of viral burden on symptoms in SARS-CoV-2 infection and adverse pulmonary reactions to biologic therapies like dupilumab. Additionally, the lab explores the immunological mechanisms underlying allergic inflammation, particularly the dual role of IL-23 in allergic sensitization versus airway inflammation. These interdisciplinary efforts integrate clinical medicine, immunology, and digital technology to improve patient outcomes in respiratory and inflammatory conditions.
Professor Hiroshi Kobayashi's research lab specializes in translational oncology with a focus on sarcoma biology, molecular diagnostics, and innovative therapeutic strategies. The lab investigates prognostic factors, rare genetic alterations such as NTRK fusions in sarcomas, and the role of targeted therapies like trabectedin and eribulin in advanced disease. It also explores surgical outcomes and quality-of-life considerations, particularly in challenging cases such as malignant fungating wounds and tumors in patients with TIO. The lab integrates clinical data with molecular pathology to improve patient stratification and treatment personalization.
Professor Takashi Goda's research lab specializes in computational mathematics and uncertainty quantification, with a focus on high-dimensional integration, quasi-Monte Carlo methods, and stochastic optimization. The lab develops advanced numerical algorithms—particularly median-based and multilevel Monte Carlo techniques—for efficient and accurate integration in weighted function spaces, including Korobov and Sobolev spaces with arbitrary smoothness. A key research direction involves constructing provably optimal QMC rules using digital nets and polynomial lattice rules, while also addressing challenges in Bayesian experimental design and CO₂ geological storage simulations. The lab bridges theoretical analysis with practical applications in environmental modeling and scientific computing.
Professor Yoshimitsu Tajima's research lab specializes in coastal and ocean engineering, with a focus on storm surge hazards, near-shore hydrodynamics, and coastal change detection. The lab conducts field surveys and develops theoretical and numerical models to understand wave transformation, run-up processes, and inundation characteristics during extreme typhoons. It also pioneers advanced remote sensing techniques, particularly using SAR imagery and machine learning, for robust shoreline monitoring. The integration of field observations, physical modeling, and data-driven methods defines the lab’s interdisciplinary approach to coastal disaster resilience and sustainable management.
Professor Kenji Shimazoe's research lab specializes in advanced medical imaging technologies, focusing on the development of high-resolution, low-power radiation detection systems for positron emission tomography (PET) and single-photon emission computed tomography (SPECT). The lab pioneers innovative signal processing techniques—such as Time-over-Threshold (ToT), Pulse Width Modulation (PWM), and Compton imaging—to enhance energy and time resolution while enabling multi-channel, highly integrated readout systems. A central theme is the utilization of radioactive tracers like 111In for dual-modality imaging through cascade gamma-ray detection and quantum sensing of nuclear spin dynamics. The lab also explores novel detector architectures using scintillators (e.g., Pr:LuAG) and avalanche photodiodes (APDs) for next-generation molecular imaging systems.
Professor Nobutaka Hirokawa's research lab specializes in cellular neuroscience and cytoskeletal biology, focusing on the molecular mechanisms underlying intracellular transport and neuronal morphogenesis. The lab investigates the roles of kinesin and dynein superfamily proteins in organelle and synaptic vesicle trafficking, particularly in neurons, using advanced electron microscopy techniques such as quick-freeze deep-etch and rotary shadowing. Key research directions include the regulation of synaptic plasticity through motor protein interactions with neurotransmitter receptors and scaffolding proteins, as well as the structural organization of cytoskeletal networks in axons and synapses. The lab integrates cell biology, genetics, and high-resolution structural imaging to elucidate how cytoskeletal dynamics support brain development, function, and neuronal survival.
Professor Masayuki Ueno's research lab focuses on gastrointestinal oncology, with a primary emphasis on rectal cancer management, immune-related adverse events from cancer immunotherapy, and the pathogenesis of nonalcoholic fatty liver disease-associated hepatocellular carcinoma. The lab investigates risk factors for metastasis, such as lateral lymph node involvement in advanced rectal cancer, and explores treatment responses and complications related to immune checkpoint inhibitors, including severe pancreatitis. Additionally, the lab contributes to understanding metabolic liver disease and optimizing treatment strategies for hepatocellular carcinoma, particularly in the context of systemic therapy and stereotactic body radiation therapy. These efforts reflect a translational approach integrating clinical oncology, hepatology, and immunology to improve patient outcomes.
Professor Norikazu Mizuochi's research lab specializes in quantum spin dynamics and defect physics in wide-bandgap semiconductors and diamond-based materials, with a focus on using electron paramagnetic resonance (EPR) techniques to investigate spin states and their coherence properties. The lab explores quantum coherence, entanglement, and hyperfine interactions in solid-state systems such as nitrogen-vacancy centers in diamond and silicon vacancy defects in 4H-SiC, aiming to develop robust quantum technologies at room temperature. Advanced pulsed EPR methods, including 2D EPR and nutation spectroscopy, are employed to determine spin multiplicity, electronic structure, and spin-spin interactions in complex defect centers and molecular systems. The research bridges fundamental spin physics with applications in quantum information processing and spin-based sensing.
