东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Kotaro Imamura's research lab specializes in mental health promotion and workplace well-being, with a focus on developing and evaluating digital mental health interventions—particularly Internet-based cognitive behavioral therapy (iCBT) and smartphone-based stress management programs—for working populations, especially in occupational settings. The lab investigates key psychological factors such as work engagement, psychological safety, and stress resilience, with a strong emphasis on evidence-based, scalable solutions for diverse populations, including nurses and employees in low- and middle-income countries. Their research integrates rigorous clinical trial methodologies with culturally adapted digital tools to improve mental health outcomes and prevent depressive episodes.
Professor Shinsuke Murakami's research lab focuses on sustainable material management and the transition toward a recycling-oriented society (Junkan-gata-shakai). The lab investigates material flow accounting, life cycle assessment, and consumer behavior related to end-of-life products, particularly in the context of electronic waste and circular economy models. Key research directions include developing environmental indicators for mining impacts, analyzing consumer preferences for circular product models (e.g., reuse, refurbishment, subscription), and estimating in-use stocks and lifespans of consumer electronics such as mobile phones. The lab integrates input-output modeling with empirical surveys to support evidence-based policy and industrial strategies for dematerialization and resource sustainability.
Professor Kenta Kimura's research lab specializes in quantum magnetism and multiferroic materials, with a focus on geometrically frustrated lattices such as triangular and pyrochlore structures. The lab investigates emergent phenomena including spin chirality, multiferroicity, and magnetoelectric coupling in antiferromagnets, particularly exploring how spin order induces ferroelectricity and enables field-tunable polarization. A key theme is the interplay between spin, lattice, and electric degrees of freedom, with advanced techniques like x-ray diffraction, strain measurements, and optical dichroism used to probe symmetry-breaking states and topological spin textures.
Professor Genta Ito's research lab focuses on the molecular and cellular mechanisms underlying leucine-rich repeat kinase 2 (LRRK2)-related Parkinson’s disease, with a central emphasis on LRRK2's dual kinase and GTPase activities. The lab investigates how LRRK2 regulates intracellular vesicular trafficking through phosphorylation of Rab GTPases, particularly Rab10, and explores the functional consequences of LRRK2 mutations and knockout in disease-relevant models. Using biochemical, proteomic, and cell biological approaches, the lab examines LRRK2's oligomeric state, post-translational modifications, and its role in organelle homeostasis, especially in lamellar bodies and endolysosomal pathways. Their work bridges structural biochemistry with neurodegenerative disease pathology, aiming to uncover therapeutic targets for Parkinson’s disease.
Professor Kazuya Ishitsuka's research lab specializes in geophysical and remote sensing technologies for monitoring Earth surface dynamics, with a focus on subsurface temperature, pressure, and permeability estimation in geothermal systems. The lab develops advanced data-driven methods—particularly physics-informed machine learning and deep learning—combined with satellite radar (InSAR) and ground-penetrating radar to analyze surface and subsurface changes. Key research directions include land subsidence and uplift monitoring, soil liquefaction detection, and the integration of geophysical data with spatial statistical models for improved environmental hazard assessment.
Professor Takayuki Hama's research lab specializes in advanced forming processes and mechanical behavior of metallic materials, with a focus on sheet and tube hydroforming, springback prediction, and deformation mechanisms in lightweight alloys such as magnesium, titanium, and aluminum. The lab combines experimental investigations with advanced finite element modeling to optimize forming processes, particularly emphasizing the effects of temperature, pressure control, and process parameters on formability and dimensional accuracy. Their work also explores time-dependent material behavior, including stress relaxation and creep, to improve the reliability and efficiency of forming technologies in automotive and structural applications.
Professor Corinthias P. M. Sianipar's research lab focuses on sustainable development and community-centered innovation, particularly in rural and developing contexts. The lab explores appropriate and environmentally sound technologies, with an emphasis on empowering marginalized communities through participatory design and knowledge transfer. Key research directions include community empowerment, sustainable technology adoption, and the role of digital connectivity in shaping rural youth mobility and development. The lab integrates social, technological, and environmental dimensions to create context-sensitive solutions that ensure long-term sustainability.
Professor Yasuyoshi Sakai's research lab focuses on the molecular mechanisms of autophagy, particularly microautophagy and micropexophagy, in yeast and other model organisms. The lab investigates membrane dynamics, organelle degradation, and the roles of specific proteins—such as those in the HOPS complex and the endosomal sorting machinery—in mediating direct lysosomal/vacuolar engulfment of cytoplasmic components. Their work integrates live-cell fluorescence microscopy, electron microscopy, and molecular genetics to dissect the stepwise machinery underlying selective organelle turnover. The lab also explores microbial metabolism, especially in methylotrophs and propane-utilizing bacteria, linking cellular degradation pathways to environmental carbon cycling.
Professor Koichiro Ohmura's research lab focuses on the immunological and genetic mechanisms underlying autoimmune arthritis, particularly rheumatoid arthritis (RA). The lab investigates the distinct immunogenetic profiles of ACPA-negative versus ACPA-positive RA, explores the developmental origins of hematopoietic and lymphoid progenitors in early embryogenesis, and examines the role of innate immune cells—especially neutrophils—in driving inflammatory arthritis through IL-17 production. A key focus is also on the unexpected role of Th2-type cytokines like IL-4 in promoting inflammatory arthritis, challenging traditional views of T-cell subset involvement in autoimmunity.
Professor Hoseok Nam's research lab specializes in sustainable energy systems, environmental pollution control, and advanced materials for clean technology applications. The lab focuses on developing innovative solutions for carbon neutrality, including hydrogen production via fusion-biomass hybrid systems, indoor air quality improvement using functionalized activated carbon filters, and techno-economic analysis of low-carbon technologies. It also conducts policy-relevant research on green financing and corporate environmental management, particularly in the context of urban industrial sectors and carbon pricing mechanisms. The lab integrates materials science, environmental engineering, and energy system modeling to address pressing challenges in climate change mitigation and sustainable development.
Professor Kazuhito Fujiyama's research lab specializes in plant molecular biology and biotechnology, with a primary focus on glyco-engineering of plants for the production of therapeutic proteins. The lab investigates plant-specific N-glycan structures—particularly β1,2-xylose and core α1,3-fucose—and develops genetic tools, such as RNAi, to eliminate these immunogenic modifications. A key achievement includes creating glyco-engineered Nicotiana benthamiana plants with predominantly high-mannose glycans, ideal for producing safe, human-compatible glycoproteins. The lab also explores the post-translational modification of recombinant proteins, exemplified by the production and structural analysis of human lactoferrin in transgenic rice.
Professor Masayuki Imanishi's research lab specializes in the development of high-quality bulk gallium nitride (GaN) single crystals using the Na-flux method, with a focus on enabling large-diameter, low-dislocation-density substrates essential for next-generation power and optoelectronic devices. The lab pioneers innovative techniques such as flux-film coating, coalescence growth from point seeds, and lateral overgrowth control to suppress defects and lattice distortion. Their work also extends to the fabrication and characterization of high-performance vertical GaN transistors, demonstrating excellent device performance with high breakdown voltage and low leakage current. The lab’s research bridges fundamental crystal growth science with practical applications in wide-bandgap semiconductor technology.
Professor Ehab S. Eshak's research lab focuses on nutritional epidemiology and the role of micronutrients in chronic disease prevention, particularly type 2 diabetes and cardiovascular diseases. The lab investigates the impact of dietary intake of water-soluble and fat-soluble vitamins, as well as seafood and lifestyle factors like smoking, on long-term health outcomes. Using large-scale prospective cohort studies in Japanese populations, the lab explores how maternal nutrition during pregnancy influences fetal development and offspring health. The research emphasizes evidence-based public health interventions to address misconceptions and improve preventive strategies.
Professor Taishin Nomura's research lab specializes in the biomechanics and neural control of human postural stability, focusing on how the central nervous system manages the inherent instability of upright standing through delayed feedback control. The lab investigates both continuous and intermittent control strategies—particularly PD-type feedback controllers—using mathematical modeling and experimental data to understand how the brain stabilizes the body in the presence of time delays and insufficient intrinsic stiffness. A key focus is on developing robust, biologically plausible control mechanisms that explain the complex, stochastic nature of postural sway while accounting for individual variability.
Professor Takeshi Yamamoto's research lab focuses on the molecular mechanisms underlying cellular homeostasis, particularly in the context of kidney disease and metabolic disorders. The lab investigates lysosomal dysfunction, autophagic flux, and lipotoxicity in renal proximal tubular cells, with a strong emphasis on how metabolic stressors like high-fat diets or saturated fatty acids disrupt cellular quality control. Key research directions include the role of transcription factor EB (TFEB) in regulating autophagy during aging and obesity, and the therapeutic potential of metabolites such as eicosapentaenoic acid (EPA) in restoring lysosomal function. The lab also explores immune cell regulation in inflammatory diseases, particularly the role of Dusp10 in modulating type 2 immune responses in eosinophilic inflammation.
Professor Shreyam Chatterjee's research lab specializes in the design and synthesis of novel organic and hybrid materials for advanced energy applications, with a strong focus on organic photovoltaics, thermoelectric materials, and functional nanocomposites. The lab explores the development of nonfullerene acceptors, electron-deficient heterocycles like NTz and FNTz, and supramolecular architectures to enhance optoelectronic properties. Key research directions include tuning molecular and supramolecular morphology, controlling charge transport mechanisms, and engineering nanomaterials such as polypyrrole–zinc oxide composites and bismuth-based oxide glasses for improved performance in solar cells and thermoelectric devices.
Professor Taiichi Otsuji's research lab specializes in terahertz science and nanoelectronics, focusing on the fundamental physics and device applications of two-dimensional electron systems and graphene. The lab explores terahertz plasmonics, including the generation, manipulation, and detection of terahertz waves using high-electron-mobility transistors and graphene-based heterostructures. Key research directions include active plasmonics, tunable terahertz emitters and detectors, and the dynamic control of 2D plasmons through optical and electrical pumping. The lab also develops advanced nanofabricated devices such as grating-gated transistors and vertical cavity structures for enhanced terahertz performance.
Professor Hiroo Uchida's research lab specializes in pediatric surgical innovation, with a primary focus on minimally invasive techniques for treating biliary atresia. The lab investigates the feasibility, safety, and outcomes of laparoscopic Kasai portoenterostomy and laparoscopic revision surgery, aiming to improve long-term biliary drainage and reduce postoperative complications. Their work contributes to advancing surgical standards in pediatric hepatobiliary surgery through clinical research and comparative outcomes analysis.
Professor Takashi Okada's research lab specializes in perinatal mental health, neuropsychiatry, and cognitive neuroscience, with a focus on depression during pregnancy and postpartum, particularly in relation to maternal psychosocial factors and social support. The lab investigates neurocognitive mechanisms underlying attentional processing, such as gaze-cuing effects, in both clinical populations (e.g., autism, schizophrenia) and healthy individuals. It also explores the impact of psychotropic medications on autonomic function and quality of life across the lifespan, especially in ADHD and schizophrenia. The lab integrates clinical, psychological, and neurophysiological approaches to understand mental health across the lifespan.
Professor Shigehiro Ohdo's research lab focuses on the molecular mechanisms linking circadian rhythms to drug metabolism, xenobiotic transport, and chronopharmacology. The lab investigates how clock-controlled transcription factors such as DBP and E4BP4 regulate the rhythmic expression of drug-metabolizing enzymes and transporters like CYP3A4 and ABCG2. Key research directions include understanding the circadian regulation of drug response, the role of nuclear receptors (e.g., PPARα) in metabolic enzyme oscillations, and the impact of biological timing on therapeutic efficacy and toxicity. The lab also explores the translational implications of these rhythms for optimizing drug dosing schedules in conditions like neuropathic pain and cancer chemotherapy.
